KEGG   Dipodomys merriami (Merriam's kangaroo rat): 138836372
Entry
138836372         CDS       T11079                                 
Symbol
Pak1
Name
(RefSeq) serine/threonine-protein kinase PAK 1
  KO
K04409  p21-activated kinase 1 [EC:2.7.11.1]
Organism
dmer  Dipodomys merriami (Merriam's kangaroo rat)
Pathway
dmer04010  MAPK signaling pathway
dmer04012  ErbB signaling pathway
dmer04014  Ras signaling pathway
dmer04024  cAMP signaling pathway
dmer04062  Chemokine signaling pathway
dmer04360  Axon guidance
dmer04392  Hippo signaling pathway - multiple species
dmer04510  Focal adhesion
dmer04625  C-type lectin receptor signaling pathway
dmer04650  Natural killer cell mediated cytotoxicity
dmer04660  T cell receptor signaling pathway
dmer04666  Fc gamma R-mediated phagocytosis
dmer04810  Regulation of actin cytoskeleton
dmer05132  Salmonella infection
dmer05170  Human immunodeficiency virus 1 infection
dmer05205  Proteoglycans in cancer
dmer05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:dmer00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    138836372 (Pak1)
   04012 ErbB signaling pathway
    138836372 (Pak1)
   04014 Ras signaling pathway
    138836372 (Pak1)
   04392 Hippo signaling pathway - multiple species
    138836372 (Pak1)
   04024 cAMP signaling pathway
    138836372 (Pak1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    138836372 (Pak1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    138836372 (Pak1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    138836372 (Pak1)
   04650 Natural killer cell mediated cytotoxicity
    138836372 (Pak1)
   04660 T cell receptor signaling pathway
    138836372 (Pak1)
   04666 Fc gamma R-mediated phagocytosis
    138836372 (Pak1)
   04062 Chemokine signaling pathway
    138836372 (Pak1)
  09158 Development and regeneration
   04360 Axon guidance
    138836372 (Pak1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    138836372 (Pak1)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    138836372 (Pak1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    138836372 (Pak1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    138836372 (Pak1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dmer01001]
    138836372 (Pak1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dmer04131]
    138836372 (Pak1)
   03036 Chromosome and associated proteins [BR:dmer03036]
    138836372 (Pak1)
Enzymes [BR:dmer01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     138836372 (Pak1)
Protein kinases [BR:dmer01001]
 Serine/threonine kinases: STE group
  STE20 family
   138836372 (Pak1)
Membrane trafficking [BR:dmer04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    138836372 (Pak1)
 Endocytosis
  Macropinocytosis
   Kinases
    138836372 (Pak1)
Chromosome and associated proteins [BR:dmer03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     138836372 (Pak1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT
Other DBs
NCBI-GeneID: 138836372
NCBI-ProteinID: XP_069891038
LinkDB
Position
Unknown
AA seq 544 aa
MSTNGLDTQDKPPAPPMRNTSTMIGAGGKDTATLNHGSKPLPPNPEEKKKKDRFYRSILP
GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN
PQAVLDVLEFYNSKKTTNSQKYMSFTDKSAEDYNSSNTLNVKTVSETPAVPPVSEDEDDD
DDATSPPVIAPRPEHTKSVYTRSVIEPLPITPTRDVATSPISPTENNTTPPDALTRNIEK
QKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQM
NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCM
DEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKR
STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGT
PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT
KNNH
NT seq 1635 nt   +upstreamnt  +downstreamnt
atgtcaactaacggcctagatactcaggacaaacccccagcccctccgatgagaaacacc
agcactatgattggagctggcggcaaagacactgcaaccctaaaccatggttccaaacct
ctgcctccaaacccagaggagaagaaaaagaaggatcgattttaccgatccattttacct
ggagataaaacaaataagaagaaggagaaggagcggccagagatttctcttccttcagat
tttgagcacacaattcatgtcggttttgatgctgtcacaggggagtttacaggcatgcca
gagcagtgggcccgcttgcttcaaacatcaaatatcactaaatcagagcaaaagaaaaac
ccacaggctgttctggatgtgttagaattttacaactctaagaagaccaccaacagtcag
aagtacatgagctttacagataagtcagccgaagattataattcttccaacactttgaat
gtgaagactgtgtctgagacccctgcggtgccacccgtttccgaagatgaagatgatgat
gatgatgctacttcccctccagtgattgctccacgcccagagcacacaaagtctgtatat
acaaggtctgtgattgaaccacttcctatcactccaactcgggatgtggctacgtctccc
atttcacctactgagaataataccactccaccagatgcgttgacccggaatattgagaag
cagaagaagaaacccaaaatgtctgatgaggagatcttagagaaattacggagcatagtg
agtgtgggcgatcctaagaagaagtatactcggtttgagaagattggacaaggtgcttca
ggaactgtgtacactgcgatggatgtagccacaggacaggaggtggccattaagcagatg
aatcttcagcagcagccgaagaaagagctgattattaatgagatcctggtcatgagggaa
aacaagaacccaaatattgtgaactacttggacagttaccttgtaggagatgagctatgg
gttgtcatggaatacttggctggaggctccttgacagatgtggtgacagaaacctgtatg
gatgaaggccagattgctgctgtgtgccgtgagtgtctgcaggccctagagttcctacat
tcaaaccaggtcattcacagagacatcaagagcgacaatattctgttgggaatggatggt
tctgtcaagttaaccgattttggattctgtgcacagataactccagaacagagcaaaagg
agcaccatggtgggaactccatattggatggcacctgaggttgtaacgcggaaggcctat
ggacccaaggttgacatctggtccctgggcatcatggctattgaaatgattgaaggggag
cccccatacctcaatgagaaccctctgagagccttgtacctcattgccaccaatgggacc
ccagaacttcagaatccagagaagctgtctgctatcttccgggactttttaaaccgctgt
ctggagatggatgtggaaaagagaggatcagctaaagagctcctgcagcatcagttcctc
aagattgccaagcccctctccagcctcactccattgattgctgcagcaaaggaggcaacc
aagaacaatcactaa

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