Dipodomys merriami (Merriam's kangaroo rat): 138841091
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Entry
138841091 CDS
T11079
Symbol
Hsd11b1
Name
(RefSeq) 11-beta-hydroxysteroid dehydrogenase 1 isoform X1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
dmer Dipodomys merriami (Merriam's kangaroo rat)
Pathway
dmer00140
Steroid hormone biosynthesis
dmer00980
Metabolism of xenobiotics by cytochrome P450
dmer01100
Metabolic pathways
dmer05204
Chemical carcinogenesis - DNA adducts
Brite
KEGG Orthology (KO) [BR:
dmer00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
138841091 (Hsd11b1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
138841091 (Hsd11b1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
138841091 (Hsd11b1)
Enzymes [BR:
dmer01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
138841091 (Hsd11b1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
DUF1776
2-Hacid_dh_C
Shikimate_DH
Pyr_redox_3
Pyr_redox_2
3HCDH_N
Motif
Other DBs
NCBI-GeneID:
138841091
NCBI-ProteinID:
XP_069897693
LinkDB
All DBs
Position
Unknown
AA seq
351 aa
AA seq
DB search
MKQKEKQRREREKRSKRGKEFNQKEVKPTWNLTSWAAMIQICDFLKSGQGGLLGPVPCLM
AFMNKYVLSLLVLFLAFYYYSENEEFKPEMLQGKKVIVTGASKGIGREIAYHLAKMGAHV
VVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMAFAEQFVAKAGKLLGGLDMLILNHI
TNSSLSPFHDDIHYVRKSMEVNFFSYVVLTVAALPMLKQSNGSIAVVSSMAGKISHPLIA
AYSASKFALDGFFSSIRTEHSLLKVNVSITLCILGLIDTDTAMEAIAGVMNLNPAPKEEC
ALEIIKGAALRQDELYYDKSRWTIFLLGNPGRKILEFFSLKNYNMEKFIKN
NT seq
1056 nt
NT seq
+upstream
nt +downstream
nt
atgaaacagaaggaaaagcagaggagggaaagagagaagaggagcaaaagaggaaaggag
ttcaatcaaaaagaagtcaaacctacttggaacctcacgagttgggcagctatgatacag
atttgtgacttcctaaaatctggacagggtggactccttgggccagttccctgtctgatg
gcttttatgaacaaatatgtgctctctcttctggtgctcttcttggccttctactactat
tctgaaaatgaagaattcaaaccagagatgctccaaggaaagaaagtgattgtgacaggg
gccagcaaggggattggaagagaaatagcttatcatctggcaaaaatgggggcccatgtg
gtggtgacagcaaggtcaaaagaaactctacaaaaggtggtatcccactgcctagaactt
ggcgcagcctcagcacactacattgctggcaccatggaagacatggcatttgcagaacaa
tttgttgctaaagcaggaaaactcctgggaggactagacatgcttattctcaaccacatc
accaactcttcattgagtccttttcatgatgatatccactatgtgcgaaaaagcatggag
gtcaactttttcagttacgtggtcctaaccgtagccgccttgcccatgctgaagcaaagc
aatggaagcatcgctgttgtctcttcaatggctgggaaaatctctcatcctctgattgct
gcctactctgcaagcaagtttgctctggatgggttcttctcttctattaggacagaacac
tcacttctgaaggtcaatgtgtcaatcactctctgtatccttggcctcatagacacagac
acagctatggaagcaatcgctggggtaatgaatttaaacccagctccaaaggaagagtgt
gcactggagatcatcaaaggggcagctctacgtcaagatgaactatactatgacaagtca
cgctggaccatattccttcttggcaatccagggaggaaaatcttggagtttttctcacta
aagaactataatatggaaaagtttataaaaaactag
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