KEGG   Dromaius novaehollandiae (emu): 112985919
Entry
112985919         CDS       T07572                                 
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like
  KO
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Organism
dne  Dromaius novaehollandiae (emu)
Pathway
dne00140  Steroid hormone biosynthesis
dne01100  Metabolic pathways
Module
dne_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
dne_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
dne_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
dne_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:dne00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    112985919
Enzymes [BR:dne01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
     112985919
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1  steroid Delta-isomerase
     112985919
SSDB
Motif
Pfam: 3Beta_HSD Epimerase GDP_Man_Dehyd NAD_binding_4 Polysacc_synt_2 NAD_binding_10 RmlD_sub_bind NmrA KR
Other DBs
NCBI-GeneID: 112985919
NCBI-ProteinID: XP_025960668
Ensembl: ENSDNVG00000015982
LinkDB
Position
Unknown
AA seq 377 aa
MSLAGVSCLVTGAGGFLGQRIVRLLLEEEEALAEIRLLDKAFSNEALKSFGKFQGKTEVK
ILEGDIRDVTFLHCACQGVSLVIHTASIIDTLGLIEKQLLWEVNVKGTQLLLEACTRCNV
QHFIYTSTIEVTGPNCRGDPVFNGDEDTVYESISKSPYAQSKTLAEDSVLKADGQVLKDG
GMLLTCALRSMYIFGEGCPFLQGHLDKSLLNKNVYLRFSRKEALVNPVYVGNIAWAHVQA
AKALQVPQKAKHIRGQFYYISDDTPHMSYADLNYELTKDLGFGIEPRLPMPLTMLYYFSL
LLEIVSFLLRPFVRYIPSTNRHLVTLLNTPFTFSYSKAQKDFGYMPRYTWEEAKQCTSQW
IAXMVPQRREYLKNKAA
NT seq 1134 nt   +upstreamnt  +downstreamnt
atgtcactggctggggtgagctgtctggtgacaggagcaggagggtttcttggccagagg
attgtccgcttactgctggaagaagaggaggcactggctgagatccgactgctggacaaa
gcttttagcaatgaagcactcaagagctttggaaagttccagggcaagacagaggtgaaa
atcctggaaggggatatccgagatgtgacgttcctgcactgtgcctgccagggggtctcc
ctcgttatccacacagcctccatcattgacaccttgggtcttatagagaagcagctgctc
tgggaagtcaatgtaaaaggtactcagctactgctggaggcatgtacccgttgtaacgtc
cagcacttcatatacactagtactatagaagtgacaggcccgaactgcagaggtgaccca
gttttcaatggtgatgaagatacagtttatgagagtatatcaaaatctccttatgcccaa
agtaagacactggcagaggattctgtgctgaaggccgatggccaggtgttaaaggatggt
ggcatgctgctgacatgtgccctgagatccatgtacatttttggagaaggatgcccattt
cttcagggtcatctggataagagtctactgaacaaaaatgtctacctgcgcttctccagg
aaggaggctttggtgaaccccgtgtatgtgggaaatatcgcctgggcgcatgtacaggca
gccaaagccctgcaggtcccacagaaagccaagcacatcagggggcagttctactacatc
tccgatgacactcctcatatgagctacgctgatctaaattacgagctgactaaggacctg
ggatttggaattgagccccggctccccatgccgctgacaatgctgtattacttctcgctg
ctgctggagatagtgagcttcttgctcaggccctttgtcagatacatcccctctaccaac
cgtcacctggtcactctgctgaacaccccattcaccttttcttacagcaaggcacagaag
gattttggctacatgccccgctacacatgggaagaggccaaacagtgcaccagtcagtgg
attgcctmcatggtcccacagagaagggagtacttgaaaaacaaggctgcctag

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