| Entry |
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| Symbol |
MAP3K5
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| Name |
(RefSeq) mitogen-activated protein kinase kinase kinase 5
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| KO |
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| Organism |
dnm Dasypus novemcinctus (nine-banded armadillo)
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| Pathway |
| dnm04141 | Protein processing in endoplasmic reticulum |
| dnm04932 | Non-alcoholic fatty liver disease |
| dnm05022 | Pathways of neurodegeneration - multiple diseases |
| dnm05208 | Chemical carcinogenesis - reactive oxygen species |
| dnm05418 | Fluid shear stress and atherosclerosis |
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| Brite |
KEGG Orthology (KO) [BR:dnm00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101411083 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101411083 (MAP3K5)
04668 TNF signaling pathway
101411083 (MAP3K5)
04071 Sphingolipid signaling pathway
101411083 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
101411083 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
101411083 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
101411083 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
101411083 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
101411083 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
101411083 (MAP3K5)
05012 Parkinson disease
101411083 (MAP3K5)
05014 Amyotrophic lateral sclerosis
101411083 (MAP3K5)
05016 Huntington disease
101411083 (MAP3K5)
05017 Spinocerebellar ataxia
101411083 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
101411083 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101411083 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
101411083 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101411083 (MAP3K5)
04932 Non-alcoholic fatty liver disease
101411083 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101411083 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:dnm01001]
101411083 (MAP3K5)
Enzymes [BR:dnm01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
101411083 (MAP3K5)
Protein kinases [BR:dnm01001]
Serine/threonine kinases: STE group
STE11 family
101411083 (MAP3K5)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1366 aa
MSTEAADGITFSVPPLGASDSCAPAEGSGGRRGAAAPATADDPPPPPAGSFWNVESAGAS
GPGCPAADALRSRGTPGDPGGRRTAVAYVINEASPGQLVVAESEALQSLREACEAAGATL
ETLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDT
NSDSLHSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELFLG
PICLPLVDRFIQLLKVAQASSSQYFRESILHDIRKARTLYTGKELATELARIRQRVDNIE
VLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGD
RAKALDVMIPLVQSEGQVASDMYCLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEP
TLQSGINYAVLLLAAGHQFNIGFTVHLSGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVL
ANDHTRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTAEQPVAKQELVDFWMDFLV
EATKTEVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSAS
SVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVDTMTEEKGRSTEEGDCD
GDSLEYDYEYDENGDRVVLGKGTYGVVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIA
LHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQI
LEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMA
PEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESM
SAEAKAFILKCFEPDPVRRACANDLLMDDFLKVSSKKKKTQPKLSALSAGSSEYLRSISL
PVPVLVEDTSSSSEYGSVSPDTELKADPFSFKTRPKSCGERDVKGMRTLFLGIPDENFED
HSAPPSPEEKDSGFFLLRKDSERRATLHRILTEDQDKVVRNLMESLAQGTEEPKLKWEHI
TTLIASLREFVRSTDRKIIASTLSKLKLELDFDSHGINQVQVVLFGFQDAVNKVLRNHNI
KPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDAADQDDMDVEDDRKEPSNPTVH
RPHAVVEDAVATSGVSTLSSTVSHDSQAAHRSLNIQLGRMKIETNRLLEELVQKEKELQA
LLHQAIEEKDQEIKHLKLKTQPIDIPGLPVCHLTSPGSNTEDSELTDWLKENGADEDTIS
RFLAEDYTLVDVLYYVTRDDLKCLRLRGGVLCSLWKAITDFRDKRF |
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| NT seq |
4101 nt +upstreamnt +downstreamnt
atgagcaccgaggcggccgacggcatcaccttctccgtcccgcccctcggcgcctcggac
tcctgcgcccctgccgagggcagcggcggccggcggggggcagcggccccggcgaccgcc
gacgacccgccgccgccgcccgcgggcagcttctggaacgtggagagcgctggcgcctcg
ggcccgggctgtcccgccgccgacgccctgcggagccggggcacccccggggaccccggc
gggcgccgcacggcggtggcctacgtgatcaacgaagcgagcccgggccagctggtggtg
gccgagagcgaggccctgcagagcctgcgggaggcgtgcgaggcggcgggcgccacgctg
gagaccctgcactttggcaagctggacttcggggagaccacggtgctggaccgcttctac
aacgcagacattgccgtggtggagatgagcgacgccttccggcagccttccttgttctac
cacctcggggtgagagagagtttcagcatggctaacaacatcatcctctactgtgatact
aactcagactccctgcattccctcaaggaaatcatttgccagaaaaatactatgtgtact
gggaactacacgttcgtgccatacatgataacgccacataacaaggtctactgctgtgat
agcagcttcatgaaagggctgacggagctgatgcagccgaatttcgagctgtttcttgga
cccatctgcttacctcttgtggatcggtttattcagcttttgaaggtggcacaagcaagt
tccagccaatatttccgggaatctatactccatgacatccggaaagctcgtactttgtat
accggtaaagaactggcaaccgaactggcaagaattcggcagcgagtcgataatattgaa
gtcttgacggcagatattgttataaatctgttgctttcctacagagatatccaggactat
gattctattgtgaagctggtagagactttagagaaactgccaacctttgatttggcctcc
catcaccatgtgaaatttcattatgcatttgcgctgaataggagaaatctccctggagat
agagcaaaagctcttgatgttatgattcccctggtgcaaagtgaaggacaagttgcttca
gatatgtactgcttagtggggcgaatctacaaagatatgtttttggactctaatttcaca
gacactgaaagtagagaccatggagcctcttggttcaaaaaggcatttgaatctgagcca
acactacagtcaggaattaattacgcggtcctcctcctggcagccgggcaccagtttaac
attggatttactgttcatctttcaggggtgaagctaagtagtcttcttggtaaaaagggg
aacttggaaaaactccagagctactgggaagttggattttttctgggggccagtgtcctg
gccaatgaccacacaagagtcattcaggcatccgaaaagctctttaagctgaagaccccg
gcatggtacctaaagtctattgtagagacaattttgatatacaagcattttgtgaagctc
actgcagaacagcctgtggccaagcaggaactcgtggacttctggatggatttcctggtg
gaggccacaaaaacagaggtcactgtggtccggtttccagtattaatattagaaccaact
aaaatctatcagccttcttatttgtctatcaacaatgaagtcgaggaaaagacaatatca
atttggcatgtgcttcctgatgataagaaaggtatacacgagtggaattttagtgcatct
tctgtcaggggagtgagtatttctaaatttgaggagcggtgctgcttcctttatgtactt
cataattctgatgatttccaaatctacttctgtacagaacttcattgtaaaaagtttttt
gaaatggtggataccatgacggaagagaagggaaggagcaccgaggagggcgactgtgat
ggcgactccctggagtatgactatgaatatgacgaaaatggtgacagagtcgttttagga
aaaggcacctacggggtcgtctacgcaggccgagacctgagcaaccaggtcagaattgct
attaaagaaatcccagagagagacagcagatactcccagcccctacatgaagaaatagca
ttgcataaacatctgaagcacaaaaatattgtccagtatctgggctctttcagtgagaat
ggcttcattaaaatcttcatggagcaggtcccaggaggaagtctttctgctctccttcgt
tccaaatggggcccgttaaaagacaacgagcaaacaattggcttttatacaaagcaaata
ctcgaaggattaaaataccttcatgacaatcagatcgttcaccgggatataaagggtgac
aacgtgctgattaacacctacagcggagtgctcaagatctcggactttgggacctcaaag
aggcttgctggcataaatccatgcactgaaactttcactggtacccttcagtacatggca
ccagaaataatagacaaaggacccaggggctacggaaaagccgccgacatctggtccctg
ggctgcacgatcatcgagatggccactgggaaaccgcccttctatgaactgggagagcca
caagcagccatgttcaaggtgggaatgtttaaagtccaccccgagatccccgagtccatg
tctgcggaggccaaggcattcatcctgaaatgttttgaaccggaccccgtcaggagggcc
tgcgcgaatgacttgcttatggacgatttcctgaaagtttccagcaagaagaaaaagaca
cagcctaagctctcagctctttcagctggatccagcgagtacctcaggagcatctccctg
ccagtgcctgtgctggtggaggacacgagcagcagcagcgagtacggctccgtctccccc
gacacggagctcaaggcagaccccttctctttcaagacgagacccaaatcctgtggggag
agagatgtgaaaggaatgcgcacgctcttcttgggcattccagatgaaaatttcgaagat
cacagtgccccaccctctcctgaagaaaaggattccggcttctttctgctgagaaaggac
agtgagcggcgagccaccctccacaggatcctaaccgaagaccaggacaaagtcgtgagg
aacctgatggaatccttggctcagggcaccgaagagccgaaactcaaatgggaacacatc
acaaccctcattgccagcctccgtgaattcgtgagatccacggaccgcaaaatcatagcc
agcacgctgtcgaagctgaagttagagctggacttcgacagccacggcataaatcaagtc
caggtggtcctcttcggctttcaagatgctgtcaacaaagtccttcggaatcacaacatc
aagccgcactggatgtttgccttggacagtatcatccggaaagcagtgcagacagctatc
accattctggttccagagctgaggccacattttagcctcgcgtctgagagcgatgccgcc
gaccaagacgacatggatgtggaagacgaccgcaaggagccctcaaacccaaccgtccac
agacctcacgccgttgtcgaggatgccgtggccacgtcgggggtgagcacgctcagctct
accgtgtcccacgattcccaggccgctcaccgctccctgaacatacagcttggaaggatg
aaaatagaaacaaacagattactggaagaattggttcaaaaagagaaagaattacaagca
ctccttcatcaagcgattgaagaaaaagatcaagaaattaagcacctgaagcttaaaacc
caaccaatagatattcctggattacctgtgtgtcaccttacttctcctggctcaaatact
gaagattctgaacttactgactggctgaaagaaaatggagctgacgaagacactataagc
cggtttttggctgaggattatacactagtggacgttctctactatgttacacgtgatgat
ttaaaatgcctgagactaagaggaggggtgctgtgctccctgtggaaggccatcaccgac
ttccgggacaagcgtttttga |
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