Dipodomys ordii (Ord's kangaroo rat): 105981481 Help Entry 105981481         CDS       T07834                                  Symbol Casp8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism dord  Dipodomys ordii (Ord's kangaroo rat) Pathway dord01524   Platinum drug resistance dord04115   p53 signaling pathway dord04210   Apoptosis dord04215   Apoptosis - multiple species dord04217   Necroptosis dord04620   Toll-like receptor signaling pathway dord04621   NOD-like receptor signaling pathway dord04622   RIG-I-like receptor signaling pathway dord04623   Cytosolic DNA-sensing pathway dord04625   C-type lectin receptor signaling pathway dord04657   IL-17 signaling pathway dord04668   TNF signaling pathway dord04932   Non-alcoholic fatty liver disease dord04936   Alcoholic liver disease dord05010   Alzheimer disease dord05016   Huntington disease dord05022   Pathways of neurodegeneration - multiple diseases dord05132   Salmonella infection dord05134   Legionellosis dord05142   Chagas disease dord05145   Toxoplasmosis dord05152   Tuberculosis dord05160   Hepatitis C dord05161   Hepatitis B dord05162   Measles dord05163   Human cytomegalovirus infection dord05164   Influenza A dord05165   Human papillomavirus infection dord05167   Kaposi sarcoma-associated herpesvirus infection dord05168   Herpes simplex virus 1 infection dord05169   Epstein-Barr virus infection dord05170   Human immunodeficiency virus 1 infection dord05200   Pathways in cancer dord05203   Viral carcinogenesis dord05416   Viral myocarditis dord05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:dord00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     105981481 (Casp8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     105981481 (Casp8)    04215 Apoptosis - multiple species     105981481 (Casp8)    04217 Necroptosis     105981481 (Casp8)    04115 p53 signaling pathway     105981481 (Casp8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     105981481 (Casp8)    04621 NOD-like receptor signaling pathway     105981481 (Casp8)    04622 RIG-I-like receptor signaling pathway     105981481 (Casp8)    04623 Cytosolic DNA-sensing pathway     105981481 (Casp8)    04625 C-type lectin receptor signaling pathway     105981481 (Casp8)    04657 IL-17 signaling pathway     105981481 (Casp8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105981481 (Casp8)    05203 Viral carcinogenesis     105981481 (Casp8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     105981481 (Casp8)    05161 Hepatitis B     105981481 (Casp8)    05160 Hepatitis C     105981481 (Casp8)    05164 Influenza A     105981481 (Casp8)    05162 Measles     105981481 (Casp8)    05168 Herpes simplex virus 1 infection     105981481 (Casp8)    05163 Human cytomegalovirus infection     105981481 (Casp8)    05167 Kaposi sarcoma-associated herpesvirus infection     105981481 (Casp8)    05169 Epstein-Barr virus infection     105981481 (Casp8)    05165 Human papillomavirus infection     105981481 (Casp8)   09171 Infectious disease: bacterial    05132 Salmonella infection     105981481 (Casp8)    05134 Legionellosis     105981481 (Casp8)    05152 Tuberculosis     105981481 (Casp8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     105981481 (Casp8)    05142 Chagas disease     105981481 (Casp8)   09164 Neurodegenerative disease    05010 Alzheimer disease     105981481 (Casp8)    05016 Huntington disease     105981481 (Casp8)    05022 Pathways of neurodegeneration - multiple diseases     105981481 (Casp8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105981481 (Casp8)    05416 Viral myocarditis     105981481 (Casp8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     105981481 (Casp8)    04932 Non-alcoholic fatty liver disease     105981481 (Casp8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     105981481 (Casp8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:dord01002]     105981481 (Casp8) Enzymes [BR:dord01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      105981481 (Casp8) Peptidases and inhibitors [BR:dord01002]  Cysteine peptidases   Family C14: caspase family    105981481 (Casp8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  105981481 NCBI-ProteinID:  XP_012866129 UniProt:  A0A1S3ERR8 LinkDB All DBs Position Unknown AA seq 473 aa AA seqDB search MDFSGYLYKIGEQLDSDELASLKFLSLDHIPQKKQEPIKDALTLFEILQEKGMLEDDNLF FLKELLFRISRLDLLQNFLSTSKENMEKELQTLGRAQISAYRVMLFQISEDVSKLELKSF KFLLSKELPRCKLDDDMSLLDIFMEMEKRVLLGDRNLDVLKKICEQINKSLLIKINDYES NRNDRTERSMSLERSPDSFLDGNMPTNLPQTPGFPGEDNQSETLDKVYQMKNKPRGYCLI FNNYDFSEARKLPSLQKMKDRNGTKLDEDTLCQTFKELHFETVLFQNYTAGDISEVLQSY QNTDHSEKDCFICCILSHGDRGIIYGTDGKKASIYDLTSYFTGSNCPSLVGKPKIFFIQA CQGQSYHKAVPVETDSETDSESQKKYIPDEADFLLGMATVKNCVSYRDPVKGTWYIQSLC QNLRERCPQGDDILTILTKVNYEVSEKIDWKNMGKQMPQPIFTLRKKLFFPPN NT seq 1422 nt NT seq  +upstreamnt  +downstreamnt atggatttcagtggatatctttacaaaatcggggaacaactggacagtgatgagttggcc tccctcaagttcctgagcctggaccacatcccacaaaagaagcaggagcccatcaaggat gccttgacattatttgagatattacaggagaagggaatgttggaggatgacaatctgttc ttcctgaaggagctgcttttccgaattagtagactagatctcctgcaaaattttctgagc acaagtaaggaaaacatggaaaaggagctccagactctaggcagggctcagatttctgcc tacagggtcatgctttttcagatttcagaagatgtaagcaaactggaattgaagtctttt aagtttttgttaagcaaggagctacccaggtgtaagctggatgatgacatgagtttgctt gatatttttatggagatggagaaaagggtccttctaggggacagaaacttagacgtcctg aagaaaatctgtgagcaaatcaacaagagcctactgatcaagataaatgattacgaatca aatagaaatgacaggacagagagaagcatgagccttgaaagaagtccagattcatttttg gatgggaatatgcccactaacttgccgcaaacaccaggctttccaggagaagacaaccag tcagagacattggacaaggtttaccaaatgaagaacaaacctcgaggatattgtttgatc ttcaacaattacgattttagcgaggcacggaagttaccttcacttcagaaaatgaaggat aggaatggaacaaaattggatgaagacaccttgtgccagacctttaaggagcttcatttt gagactgtacttttccaaaattacacagcaggggacatcagtgaggttctgcaatcctac caaaatacagaccacagtgagaaggactgcttcatctgctgtatcctgtcccatggagac aggggcattatctatggcactgatggaaagaaggcctccatctatgatctgacctcttat ttcactggttccaattgcccttcactggttggaaaaccaaaaatcttttttattcaagct tgccaagggcagagctatcacaaagctgtacctgttgagactgactcagagacagactca gaatctcaaaagaaatatatccctgatgaggctgactttctgctggggatggctactgta aaaaactgtgtatcctaccgagatcctgtgaaggggacgtggtatatccaatctctttgc cagaacctgagggaaagatgtcctcaaggtgatgatatccttactatcctgaccaaagtg aattatgaagtaagcgagaaaattgattggaagaacatggggaaacagatgcctcagcct attttcacactaaggaaaaaactctttttccctcctaattaa

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