Dipodomys ordii (Ord's kangaroo rat): 105981663
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Entry
105981663 CDS
T07834
Symbol
Plcg1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
KO
K01116
phosphatidylinositol phospholipase C, gamma-1 [EC:
3.1.4.11
]
Organism
dord
Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord00562
Inositol phosphate metabolism
dord01100
Metabolic pathways
dord01521
EGFR tyrosine kinase inhibitor resistance
dord04012
ErbB signaling pathway
dord04014
Ras signaling pathway
dord04015
Rap1 signaling pathway
dord04020
Calcium signaling pathway
dord04062
Chemokine signaling pathway
dord04064
NF-kappa B signaling pathway
dord04066
HIF-1 signaling pathway
dord04070
Phosphatidylinositol signaling system
dord04072
Phospholipase D signaling pathway
dord04360
Axon guidance
dord04370
VEGF signaling pathway
dord04613
Neutrophil extracellular trap formation
dord04650
Natural killer cell mediated cytotoxicity
dord04658
Th1 and Th2 cell differentiation
dord04659
Th17 cell differentiation
dord04660
T cell receptor signaling pathway
dord04664
Fc epsilon RI signaling pathway
dord04666
Fc gamma R-mediated phagocytosis
dord04670
Leukocyte transendothelial migration
dord04722
Neurotrophin signaling pathway
dord04750
Inflammatory mediator regulation of TRP channels
dord04919
Thyroid hormone signaling pathway
dord04933
AGE-RAGE signaling pathway in diabetic complications
dord04935
Growth hormone synthesis, secretion and action
dord05012
Parkinson disease
dord05022
Pathways of neurodegeneration - multiple diseases
dord05135
Yersinia infection
dord05167
Kaposi sarcoma-associated herpesvirus infection
dord05170
Human immunodeficiency virus 1 infection
dord05171
Coronavirus disease - COVID-19
dord05200
Pathways in cancer
dord05205
Proteoglycans in cancer
dord05206
MicroRNAs in cancer
dord05214
Glioma
dord05223
Non-small cell lung cancer
dord05225
Hepatocellular carcinoma
dord05231
Choline metabolism in cancer
dord05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
dord05417
Lipid and atherosclerosis
Module
dord_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
dord00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
105981663 (Plcg1)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
105981663 (Plcg1)
04014 Ras signaling pathway
105981663 (Plcg1)
04015 Rap1 signaling pathway
105981663 (Plcg1)
04370 VEGF signaling pathway
105981663 (Plcg1)
04064 NF-kappa B signaling pathway
105981663 (Plcg1)
04066 HIF-1 signaling pathway
105981663 (Plcg1)
04020 Calcium signaling pathway
105981663 (Plcg1)
04070 Phosphatidylinositol signaling system
105981663 (Plcg1)
04072 Phospholipase D signaling pathway
105981663 (Plcg1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
105981663 (Plcg1)
04650 Natural killer cell mediated cytotoxicity
105981663 (Plcg1)
04660 T cell receptor signaling pathway
105981663 (Plcg1)
04658 Th1 and Th2 cell differentiation
105981663 (Plcg1)
04659 Th17 cell differentiation
105981663 (Plcg1)
04664 Fc epsilon RI signaling pathway
105981663 (Plcg1)
04666 Fc gamma R-mediated phagocytosis
105981663 (Plcg1)
04670 Leukocyte transendothelial migration
105981663 (Plcg1)
04062 Chemokine signaling pathway
105981663 (Plcg1)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
105981663 (Plcg1)
04919 Thyroid hormone signaling pathway
105981663 (Plcg1)
09156 Nervous system
04722 Neurotrophin signaling pathway
105981663 (Plcg1)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
105981663 (Plcg1)
09158 Development and regeneration
04360 Axon guidance
105981663 (Plcg1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105981663 (Plcg1)
05206 MicroRNAs in cancer
105981663 (Plcg1)
05205 Proteoglycans in cancer
105981663 (Plcg1)
05231 Choline metabolism in cancer
105981663 (Plcg1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
105981663 (Plcg1)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
105981663 (Plcg1)
05214 Glioma
105981663 (Plcg1)
05223 Non-small cell lung cancer
105981663 (Plcg1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
105981663 (Plcg1)
05171 Coronavirus disease - COVID-19
105981663 (Plcg1)
05167 Kaposi sarcoma-associated herpesvirus infection
105981663 (Plcg1)
09171 Infectious disease: bacterial
05135 Yersinia infection
105981663 (Plcg1)
09164 Neurodegenerative disease
05012 Parkinson disease
105981663 (Plcg1)
05022 Pathways of neurodegeneration - multiple diseases
105981663 (Plcg1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105981663 (Plcg1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
105981663 (Plcg1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105981663 (Plcg1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dord04131
]
105981663 (Plcg1)
Enzymes [BR:
dord01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
105981663 (Plcg1)
Membrane trafficking [BR:
dord04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
105981663 (Plcg1)
Endocytosis
Macropinocytosis
Phospholipase C
105981663 (Plcg1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
PH
C2
SH3_1
EF-hand_PLCG1
SH3_9
SH3_2
PH_12
GDPD
EF-hand_6
EF-hand_7
Motif
Other DBs
NCBI-GeneID:
105981663
NCBI-ProteinID:
XP_012866352
Ensembl:
ENSDORG00000012133
UniProt:
A0A1S3ESD6
LinkDB
All DBs
Position
Unknown
AA seq
1291 aa
AA seq
DB search
MAGAASPCANGCGPGTPSDAEVLHLCRNLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
SLQATSEDEVNMWIKGLTWLTEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNM
LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRT
GERPELCRVSLSEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA
QQRNMAQYFKKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSVM
YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASG
STELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDALYDLITHYQQVPLRCNEFEMRLSEPVPQT
NAHESKEWYHSSLTRTQAEHMLMRVPRDGAFLVRKRSEPNSYAISFRAEGKIKHCRVQQE
GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
GFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLW
FPSNYVEEMISPAALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS
MTSVTHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYC
RPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDS
SNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKS
SLRGLEPCAICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSVKQKTEFVVDNGLNPVW
PAKPFHFQISNPKFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDL
ELASLLIKIDIFPAKENGDLSPFGGTSLRERSSDASSNQLFHGRAREGSLEGRYQQPFED
FRISQEHLADHFDSRERRAPRRTRVNGDNRL
NT seq
3876 nt
NT seq
+upstream
nt +downstream
nt
atggcgggcgccgcgtctccctgcgccaacggctgcgggcccggcacgccctcggacgcc
gaggtgctgcacctctgccgcaacctcgaggtgggcaccgtcatgactttgttctactcc
aagaagtcgcagcggcccgagaggaagaccttccaggtcaagctggagacgcgccagatc
acgtggagccgtggcgccgacaagatcgagggggccattgatattcgtgaaattaaggag
attcgcccagggaagacctcacgggactttgaccgctatcaagaggaccctgctttccgg
cctgaccagtcacactgctttgtcatcctctatggaatggaattccgcttgaagaccctg
agcctgcaagccacgtctgaggatgaagtcaacatgtggatcaaaggcttaacttggttg
acagaggacacattgcaggcagccacgcccctacagattgagaggtggcttcggaaacag
ttctactcggtggatcgcaatcgtgaggatcgtatatcagccaaggacctgaaaaacatg
ctgtctcaggtcaactaccgggtgcctaacatgcgcttcctccgggagcggctgacggac
ctggagcagcgcagcggggatatcacctatggacagtttgcacagttgtaccgcagcctc
atgtacagcgcccagaagacgatggacctccctttcttggaagccagcactctgaggact
ggagaacggccagaactctgccgagtgtctctttcagaattccagcagttcctccttgag
taccagggggagctgtgggctgttgaccggctccaggtacaggaattcatgctcagcttt
ctccgagatcccttgcgagagatcgaggagccatacttcttcctggatgagtttgtcacc
ttcctgttctccaaagagaacagtgtgtggaactctcagctggatgcagtgtgcccagac
accatgaacaaccctctgtcccactactggatctcctcctcacacaatacatacctgacc
ggggaccagttctccagcgagtcttccctggaagcctatgctcgctgcctgcggatgggc
tgccgctgcatcgagttggactgctgggatggcccagacggcatgcctgtcatttaccat
gggcacacccttaccaccaagataaagttctcagacgttctgcacaccatcaaagagcat
gcctttgtggcctcagaatacccagtcatcctgtccattgaggaccactgtagcatagcc
cagcagcggaacatggcccagtacttcaagaaggtgctcggggatactctcctcaccaag
cccgtggacattgctgctgatgggcttccctcacccaaccagcttaagaggaagatcctc
atcaagcacaagaagctggctgagggcagtgcctatgaggaagtgcccacctctgtgatg
tactctgagaatgacatcagcaactccatcaagaatggtattctgtacctggaggaccct
gtgaaccatgaatggtatccccattacttcgttctgaccagcagcaagatctactactct
gaggagaccagcagtgatcagggcaacgaggatgaggaggagcccaaagaggccagtggg
agcacagagctacactccagtgagaagtggttccatgggaagcttggggctggccgggat
gggcggcacattgccgagcgcctgctcaccgagtactgcatcgagactggggcccccgac
ggctccttcctagtgcgggagagtgagaccttcgtgggcgactacacgctctctttctgg
cggaatgggaaagtccagcattgccgcatccattcccggcaggatgctgggacccccaag
ttcttcttgaccgacaaccttgtctttgacgccctctatgacctcatcacacactatcag
caggtgcctctacgctgcaatgagtttgagatgcgcctttcagagcccgtcccacagacc
aatgcccacgagagcaaagagtggtaccattcaagcctgaccagaacacaggctgagcac
atgctgatgcgtgtgccccgtgatggagccttcctggtgcggaaacggagcgagcccaat
tcgtatgccatctccttccgggctgagggcaaaatcaagcactgtcgagtccagcaggag
ggccagactgtgatgctggggaactctgagtttgacagccttgtcgatctcatcagctac
tatgagaagcacccattgtaccgcaagatgaagctgcgctaccccatcaatgaggaggct
ctggagaagatcggcactgctgagcccgactatggggccctgtacgagggacgcaatcct
ggtttctatgtggaggcgaaccctatgccaacattcaagtgtgcagtcaaagccctcttt
gactacaaggcccagagagaggatgagcttaccttcaccaagagcgccatcatccagaac
gtggagaagcaagacgggggctggtggaggggagattatggtgggaagaagcagctgtgg
ttcccatcaaattatgtggaagagatgatcagccctgcagctctggagcctgagagggag
cacttggacgagaacagccctctgggggacttgctgcggggggtcttggatgtgccagcc
tgtcagattgccatccgtcctgagggcaagaacaaccggctcttcgtcttctccatcagc
atgacatcagtaacccactggtccttagatgttgctgcagactcacaggaggagctgcaa
gactgggtgaagaagatccgtgaagtggcgcagaccgcagatgccaggctcaccgagggg
aagatgatggaaaggaggaagaagattgccctggagctttctgaacttgtcgtctactgc
cggcctgttccctttgatgaagagaagattggcacagaacgggcctgctaccgggatatg
tcatccttcccggaaaccaaggctgagaagtatgtgaacaaggccaaaggcaagaagttc
ctccagtacaaccggctgcagctctcccgcatctaccccaagggccagcggctggattcc
tctaattatgaccctttgcctatgtggatctgtggcagtcaacttgtagcgctcaacttc
cagaccccagacaagcctatgcaaatgaaccaggccctcttcatggcgggtgggcactgt
ggctacgtgctgcaaccaagcaccatgcgagatgaggcctttgacccgtttgacaagagc
agcctccggggactagagccctgcgctatctgcatcgaggtactgggggcccggcatctg
ccaaagaatggccggggcattgtgtgtcctttcgtggagattgaggtagctggggctgag
tatgacagcgttaagcagaagacagagttcgtagtggacaatggtctgaaccctgtatgg
cctgccaagccctttcacttccagattagtaaccctaaatttgccttccttcgctttgtg
gtatatgaggaagacatgtttagtgaccagaacttcttggctcaggctactttcccagta
aagggattgaagactggatacagagcagtgcctttgaaaaacaactacagtgaagacctg
gagttggcttccctgctcatcaagattgacattttccctgctaaggagaatggagacctc
agtccctttggtggtacatccctgcgggaacggagctcagatgcctcctccaaccagctg
ttccatggccgggcccgagaagggtccttggaaggccgctatcagcagccgtttgaggac
ttccgcatctcccaggagcatcttgcagaccattttgacagtcgagagcgaagggcccca
agaaggactcgagtcaatggagacaaccgcctctag
DBGET
integrated database retrieval system
