KEGG   Dipodomys ordii (Ord's kangaroo rat): 105986178
Entry
105986178         CDS       T07834                                 
Symbol
Pik3r3
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit gamma
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
dord  Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord01521  EGFR tyrosine kinase inhibitor resistance
dord01522  Endocrine resistance
dord01524  Platinum drug resistance
dord04012  ErbB signaling pathway
dord04014  Ras signaling pathway
dord04015  Rap1 signaling pathway
dord04024  cAMP signaling pathway
dord04062  Chemokine signaling pathway
dord04066  HIF-1 signaling pathway
dord04068  FoxO signaling pathway
dord04070  Phosphatidylinositol signaling system
dord04071  Sphingolipid signaling pathway
dord04072  Phospholipase D signaling pathway
dord04081  Hormone signaling
dord04140  Autophagy - animal
dord04150  mTOR signaling pathway
dord04151  PI3K-Akt signaling pathway
dord04152  AMPK signaling pathway
dord04210  Apoptosis
dord04211  Longevity regulating pathway
dord04213  Longevity regulating pathway - multiple species
dord04218  Cellular senescence
dord04360  Axon guidance
dord04370  VEGF signaling pathway
dord04380  Osteoclast differentiation
dord04510  Focal adhesion
dord04550  Signaling pathways regulating pluripotency of stem cells
dord04611  Platelet activation
dord04613  Neutrophil extracellular trap formation
dord04620  Toll-like receptor signaling pathway
dord04625  C-type lectin receptor signaling pathway
dord04630  JAK-STAT signaling pathway
dord04650  Natural killer cell mediated cytotoxicity
dord04660  T cell receptor signaling pathway
dord04662  B cell receptor signaling pathway
dord04664  Fc epsilon RI signaling pathway
dord04666  Fc gamma R-mediated phagocytosis
dord04668  TNF signaling pathway
dord04670  Leukocyte transendothelial migration
dord04722  Neurotrophin signaling pathway
dord04725  Cholinergic synapse
dord04750  Inflammatory mediator regulation of TRP channels
dord04810  Regulation of actin cytoskeleton
dord04910  Insulin signaling pathway
dord04914  Progesterone-mediated oocyte maturation
dord04915  Estrogen signaling pathway
dord04917  Prolactin signaling pathway
dord04919  Thyroid hormone signaling pathway
dord04923  Regulation of lipolysis in adipocytes
dord04926  Relaxin signaling pathway
dord04929  GnRH secretion
dord04930  Type II diabetes mellitus
dord04931  Insulin resistance
dord04932  Non-alcoholic fatty liver disease
dord04933  AGE-RAGE signaling pathway in diabetic complications
dord04935  Growth hormone synthesis, secretion and action
dord04960  Aldosterone-regulated sodium reabsorption
dord04973  Carbohydrate digestion and absorption
dord05010  Alzheimer disease
dord05017  Spinocerebellar ataxia
dord05020  Prion disease
dord05100  Bacterial invasion of epithelial cells
dord05135  Yersinia infection
dord05142  Chagas disease
dord05146  Amoebiasis
dord05160  Hepatitis C
dord05161  Hepatitis B
dord05162  Measles
dord05163  Human cytomegalovirus infection
dord05164  Influenza A
dord05165  Human papillomavirus infection
dord05166  Human T-cell leukemia virus 1 infection
dord05167  Kaposi sarcoma-associated herpesvirus infection
dord05168  Herpes simplex virus 1 infection
dord05169  Epstein-Barr virus infection
dord05170  Human immunodeficiency virus 1 infection
dord05171  Coronavirus disease - COVID-19
dord05200  Pathways in cancer
dord05203  Viral carcinogenesis
dord05205  Proteoglycans in cancer
dord05206  MicroRNAs in cancer
dord05207  Chemical carcinogenesis - receptor activation
dord05208  Chemical carcinogenesis - reactive oxygen species
dord05210  Colorectal cancer
dord05211  Renal cell carcinoma
dord05212  Pancreatic cancer
dord05213  Endometrial cancer
dord05214  Glioma
dord05215  Prostate cancer
dord05218  Melanoma
dord05220  Chronic myeloid leukemia
dord05221  Acute myeloid leukemia
dord05222  Small cell lung cancer
dord05223  Non-small cell lung cancer
dord05224  Breast cancer
dord05225  Hepatocellular carcinoma
dord05226  Gastric cancer
dord05230  Central carbon metabolism in cancer
dord05231  Choline metabolism in cancer
dord05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
dord05415  Diabetic cardiomyopathy
dord05417  Lipid and atherosclerosis
dord05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dord00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    105986178 (Pik3r3)
   04014 Ras signaling pathway
    105986178 (Pik3r3)
   04015 Rap1 signaling pathway
    105986178 (Pik3r3)
   04370 VEGF signaling pathway
    105986178 (Pik3r3)
   04630 JAK-STAT signaling pathway
    105986178 (Pik3r3)
   04668 TNF signaling pathway
    105986178 (Pik3r3)
   04066 HIF-1 signaling pathway
    105986178 (Pik3r3)
   04068 FoxO signaling pathway
    105986178 (Pik3r3)
   04070 Phosphatidylinositol signaling system
    105986178 (Pik3r3)
   04072 Phospholipase D signaling pathway
    105986178 (Pik3r3)
   04071 Sphingolipid signaling pathway
    105986178 (Pik3r3)
   04024 cAMP signaling pathway
    105986178 (Pik3r3)
   04151 PI3K-Akt signaling pathway
    105986178 (Pik3r3)
   04152 AMPK signaling pathway
    105986178 (Pik3r3)
   04150 mTOR signaling pathway
    105986178 (Pik3r3)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    105986178 (Pik3r3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105986178 (Pik3r3)
  09143 Cell growth and death
   04210 Apoptosis
    105986178 (Pik3r3)
   04218 Cellular senescence
    105986178 (Pik3r3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105986178 (Pik3r3)
   04550 Signaling pathways regulating pluripotency of stem cells
    105986178 (Pik3r3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105986178 (Pik3r3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105986178 (Pik3r3)
   04613 Neutrophil extracellular trap formation
    105986178 (Pik3r3)
   04620 Toll-like receptor signaling pathway
    105986178 (Pik3r3)
   04625 C-type lectin receptor signaling pathway
    105986178 (Pik3r3)
   04650 Natural killer cell mediated cytotoxicity
    105986178 (Pik3r3)
   04660 T cell receptor signaling pathway
    105986178 (Pik3r3)
   04662 B cell receptor signaling pathway
    105986178 (Pik3r3)
   04664 Fc epsilon RI signaling pathway
    105986178 (Pik3r3)
   04666 Fc gamma R-mediated phagocytosis
    105986178 (Pik3r3)
   04670 Leukocyte transendothelial migration
    105986178 (Pik3r3)
   04062 Chemokine signaling pathway
    105986178 (Pik3r3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105986178 (Pik3r3)
   04923 Regulation of lipolysis in adipocytes
    105986178 (Pik3r3)
   04929 GnRH secretion
    105986178 (Pik3r3)
   04915 Estrogen signaling pathway
    105986178 (Pik3r3)
   04914 Progesterone-mediated oocyte maturation
    105986178 (Pik3r3)
   04917 Prolactin signaling pathway
    105986178 (Pik3r3)
   04926 Relaxin signaling pathway
    105986178 (Pik3r3)
   04935 Growth hormone synthesis, secretion and action
    105986178 (Pik3r3)
   04919 Thyroid hormone signaling pathway
    105986178 (Pik3r3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    105986178 (Pik3r3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    105986178 (Pik3r3)
  09156 Nervous system
   04725 Cholinergic synapse
    105986178 (Pik3r3)
   04722 Neurotrophin signaling pathway
    105986178 (Pik3r3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105986178 (Pik3r3)
  09158 Development and regeneration
   04360 Axon guidance
    105986178 (Pik3r3)
   04380 Osteoclast differentiation
    105986178 (Pik3r3)
  09149 Aging
   04211 Longevity regulating pathway
    105986178 (Pik3r3)
   04213 Longevity regulating pathway - multiple species
    105986178 (Pik3r3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105986178 (Pik3r3)
   05206 MicroRNAs in cancer
    105986178 (Pik3r3)
   05205 Proteoglycans in cancer
    105986178 (Pik3r3)
   05207 Chemical carcinogenesis - receptor activation
    105986178 (Pik3r3)
   05208 Chemical carcinogenesis - reactive oxygen species
    105986178 (Pik3r3)
   05203 Viral carcinogenesis
    105986178 (Pik3r3)
   05230 Central carbon metabolism in cancer
    105986178 (Pik3r3)
   05231 Choline metabolism in cancer
    105986178 (Pik3r3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105986178 (Pik3r3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105986178 (Pik3r3)
   05212 Pancreatic cancer
    105986178 (Pik3r3)
   05225 Hepatocellular carcinoma
    105986178 (Pik3r3)
   05226 Gastric cancer
    105986178 (Pik3r3)
   05214 Glioma
    105986178 (Pik3r3)
   05221 Acute myeloid leukemia
    105986178 (Pik3r3)
   05220 Chronic myeloid leukemia
    105986178 (Pik3r3)
   05218 Melanoma
    105986178 (Pik3r3)
   05211 Renal cell carcinoma
    105986178 (Pik3r3)
   05215 Prostate cancer
    105986178 (Pik3r3)
   05213 Endometrial cancer
    105986178 (Pik3r3)
   05224 Breast cancer
    105986178 (Pik3r3)
   05222 Small cell lung cancer
    105986178 (Pik3r3)
   05223 Non-small cell lung cancer
    105986178 (Pik3r3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105986178 (Pik3r3)
   05170 Human immunodeficiency virus 1 infection
    105986178 (Pik3r3)
   05161 Hepatitis B
    105986178 (Pik3r3)
   05160 Hepatitis C
    105986178 (Pik3r3)
   05171 Coronavirus disease - COVID-19
    105986178 (Pik3r3)
   05164 Influenza A
    105986178 (Pik3r3)
   05162 Measles
    105986178 (Pik3r3)
   05168 Herpes simplex virus 1 infection
    105986178 (Pik3r3)
   05163 Human cytomegalovirus infection
    105986178 (Pik3r3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105986178 (Pik3r3)
   05169 Epstein-Barr virus infection
    105986178 (Pik3r3)
   05165 Human papillomavirus infection
    105986178 (Pik3r3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    105986178 (Pik3r3)
   05100 Bacterial invasion of epithelial cells
    105986178 (Pik3r3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    105986178 (Pik3r3)
   05142 Chagas disease
    105986178 (Pik3r3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105986178 (Pik3r3)
   05017 Spinocerebellar ataxia
    105986178 (Pik3r3)
   05020 Prion disease
    105986178 (Pik3r3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105986178 (Pik3r3)
   05418 Fluid shear stress and atherosclerosis
    105986178 (Pik3r3)
   05415 Diabetic cardiomyopathy
    105986178 (Pik3r3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    105986178 (Pik3r3)
   04932 Non-alcoholic fatty liver disease
    105986178 (Pik3r3)
   04931 Insulin resistance
    105986178 (Pik3r3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105986178 (Pik3r3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105986178 (Pik3r3)
   01524 Platinum drug resistance
    105986178 (Pik3r3)
   01522 Endocrine resistance
    105986178 (Pik3r3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dord04131]
    105986178 (Pik3r3)
Membrane trafficking [BR:dord04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    105986178 (Pik3r3)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 SH2_1 Legum_prodom PI_PP_I Exonuc_VII_L
Other DBs
NCBI-GeneID: 105986178
NCBI-ProteinID: XP_012872428
Ensembl: ENSDORG00000025153
UniProt: A0A1S3F702
LinkDB
Position
Unknown
AA seq 497 aa
MEERSRAERLGEIKVKVKDVLFVVFVDPENSRTPGAMYNTVWSMDRDDADWREVMMPYST
ELIFYIEMDPPALPPKPPKPMTSAVTNGMKDSCVALQDAEWYWGDISREEVNDKLRDMPD
GTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELINHYHHES
LAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKKLQEYHSQYQEKSKEYDRLYEEYTR
TSQEIQMKRTAIEAFNETIKIFEEQCHTQEQYSKEYIERFRREGNEKEIERIMMNFDKLK
SRLGEIHDSKMRLEQDLKKQALDNREIDKKMNSIKPDLIQLRKIRDQHLVWLNHKGVRQK
RLNTWLGIKNEDVDESYYINEEEENLPHYDEKTWFVEDINRVQAEDLLCGKPDGSFLIRE
SSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYNLYSSLKELVLHYQQTSLVQHNDSL
NVRLAYPVHAQMPSLCR
NT seq 1494 nt   +upstreamnt  +downstreamnt
atggaagaaaggagccgggcagaacggttgggagagataaaagtcaaggtgaaggacgtc
ctcttcgtcgtgtttgtggaccctgagaattctcgtaccccgggcgccatgtacaatacg
gtgtggagtatggaccgcgatgacgcagactggagggaggtgatgatgccctattcgaca
gaactgatattttatattgaaatggatcctccagctcttccaccaaagccacctaagcca
atgacttcagcagttacaaatgggatgaaagacagttgcgttgctcttcaggatgcagaa
tggtactggggggatatttccagggaggaggtaaatgacaaattacgggacatgccagat
ggtaccttcttggttcgagatgcctcaacaaaaatgcagggagattatactttgactttg
aggaaaggaggcaataataagttaataaagatctatcatcgggatggtaaatacggcttt
tctgatcctttgacatttaattctgtggtggagctcattaaccactatcatcatgaatct
cttgctcagtacaatcccaaacttgacgtgaagctgatgtacccagtgtccagatatcaa
caggatcagttggtaaaagaagataatattgatgcagtaggcaaaaaacttcaagagtac
cactctcagtatcaggaaaagagtaaagaatatgacaggctatatgaagaatataccaga
acatcccaggaaatacaaatgaagaggactgccattgaagcttttaatgaaacaattaaa
atatttgaggagcaatgtcacacacaagagcaatatagcaaagaatatattgagcggttt
cgcagagaaggaaatgaaaaggaaattgaacgaattatgatgaattttgacaaattgaaa
tcacgtcttggtgagattcatgatagcaaaatgcgtctggaacaggatttgaagaaacaa
gctttggacaaccgggaaatagataaaaaaatgaacagtatcaaacctgacctgatccag
ctgcgcaagatacgagatcagcatcttgtgtggcttaatcacaaaggagtgagacagaag
cgcctcaatacctggctgggaataaaaaatgaggatgttgatgagtcctattatatcaat
gaggaagaggaaaacctgccacattatgatgagaaaacttggtttgttgaggatatcaat
cgagtacaagccgaggacttgctctgtgggaagcctgatggttcattcttaattcgtgag
agcagcaagaaaggatgctatgcttgttctgtagttgctgatggggaggtgaagcactgt
gtgatctacagtacggcacgaggatatggcttcgcagagccctacaacctgtacagctcc
ctgaaggagctggtgctccactaccagcagacatccctggtccagcacaacgactccctc
aatgtcaggcttgcctaccctgtccatgcacagatgccttcgctctgcagataa

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