Dipodomys ordii (Ord's kangaroo rat): 105990471
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Entry
105990471 CDS
T07834
Symbol
Map2k2
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 2
KO
K04369
mitogen-activated protein kinase kinase 2 [EC:
2.7.12.2
]
Organism
dord
Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord01521
EGFR tyrosine kinase inhibitor resistance
dord01522
Endocrine resistance
dord04010
MAPK signaling pathway
dord04012
ErbB signaling pathway
dord04014
Ras signaling pathway
dord04015
Rap1 signaling pathway
dord04022
cGMP-PKG signaling pathway
dord04024
cAMP signaling pathway
dord04066
HIF-1 signaling pathway
dord04068
FoxO signaling pathway
dord04071
Sphingolipid signaling pathway
dord04072
Phospholipase D signaling pathway
dord04140
Autophagy - animal
dord04148
Efferocytosis
dord04150
mTOR signaling pathway
dord04151
PI3K-Akt signaling pathway
dord04210
Apoptosis
dord04218
Cellular senescence
dord04270
Vascular smooth muscle contraction
dord04370
VEGF signaling pathway
dord04371
Apelin signaling pathway
dord04540
Gap junction
dord04550
Signaling pathways regulating pluripotency of stem cells
dord04613
Neutrophil extracellular trap formation
dord04620
Toll-like receptor signaling pathway
dord04650
Natural killer cell mediated cytotoxicity
dord04660
T cell receptor signaling pathway
dord04662
B cell receptor signaling pathway
dord04664
Fc epsilon RI signaling pathway
dord04720
Long-term potentiation
dord04722
Neurotrophin signaling pathway
dord04730
Long-term depression
dord04810
Regulation of actin cytoskeleton
dord04910
Insulin signaling pathway
dord04912
GnRH signaling pathway
dord04915
Estrogen signaling pathway
dord04916
Melanogenesis
dord04917
Prolactin signaling pathway
dord04919
Thyroid hormone signaling pathway
dord04921
Oxytocin signaling pathway
dord04926
Relaxin signaling pathway
dord04929
GnRH secretion
dord04934
Cushing syndrome
dord04935
Growth hormone synthesis, secretion and action
dord05010
Alzheimer disease
dord05022
Pathways of neurodegeneration - multiple diseases
dord05132
Salmonella infection
dord05135
Yersinia infection
dord05160
Hepatitis C
dord05161
Hepatitis B
dord05163
Human cytomegalovirus infection
dord05164
Influenza A
dord05165
Human papillomavirus infection
dord05166
Human T-cell leukemia virus 1 infection
dord05167
Kaposi sarcoma-associated herpesvirus infection
dord05170
Human immunodeficiency virus 1 infection
dord05200
Pathways in cancer
dord05205
Proteoglycans in cancer
dord05206
MicroRNAs in cancer
dord05207
Chemical carcinogenesis - receptor activation
dord05208
Chemical carcinogenesis - reactive oxygen species
dord05210
Colorectal cancer
dord05211
Renal cell carcinoma
dord05213
Endometrial cancer
dord05214
Glioma
dord05215
Prostate cancer
dord05216
Thyroid cancer
dord05218
Melanoma
dord05219
Bladder cancer
dord05220
Chronic myeloid leukemia
dord05221
Acute myeloid leukemia
dord05223
Non-small cell lung cancer
dord05224
Breast cancer
dord05225
Hepatocellular carcinoma
dord05226
Gastric cancer
dord05230
Central carbon metabolism in cancer
dord05231
Choline metabolism in cancer
dord05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
dord00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105990471 (Map2k2)
04012 ErbB signaling pathway
105990471 (Map2k2)
04014 Ras signaling pathway
105990471 (Map2k2)
04015 Rap1 signaling pathway
105990471 (Map2k2)
04370 VEGF signaling pathway
105990471 (Map2k2)
04371 Apelin signaling pathway
105990471 (Map2k2)
04066 HIF-1 signaling pathway
105990471 (Map2k2)
04068 FoxO signaling pathway
105990471 (Map2k2)
04072 Phospholipase D signaling pathway
105990471 (Map2k2)
04071 Sphingolipid signaling pathway
105990471 (Map2k2)
04024 cAMP signaling pathway
105990471 (Map2k2)
04022 cGMP-PKG signaling pathway
105990471 (Map2k2)
04151 PI3K-Akt signaling pathway
105990471 (Map2k2)
04150 mTOR signaling pathway
105990471 (Map2k2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
105990471 (Map2k2)
04148 Efferocytosis
105990471 (Map2k2)
09143 Cell growth and death
04210 Apoptosis
105990471 (Map2k2)
04218 Cellular senescence
105990471 (Map2k2)
09144 Cellular community - eukaryotes
04540 Gap junction
105990471 (Map2k2)
04550 Signaling pathways regulating pluripotency of stem cells
105990471 (Map2k2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
105990471 (Map2k2)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
105990471 (Map2k2)
04620 Toll-like receptor signaling pathway
105990471 (Map2k2)
04650 Natural killer cell mediated cytotoxicity
105990471 (Map2k2)
04660 T cell receptor signaling pathway
105990471 (Map2k2)
04662 B cell receptor signaling pathway
105990471 (Map2k2)
04664 Fc epsilon RI signaling pathway
105990471 (Map2k2)
09152 Endocrine system
04910 Insulin signaling pathway
105990471 (Map2k2)
04929 GnRH secretion
105990471 (Map2k2)
04912 GnRH signaling pathway
105990471 (Map2k2)
04915 Estrogen signaling pathway
105990471 (Map2k2)
04917 Prolactin signaling pathway
105990471 (Map2k2)
04921 Oxytocin signaling pathway
105990471 (Map2k2)
04926 Relaxin signaling pathway
105990471 (Map2k2)
04935 Growth hormone synthesis, secretion and action
105990471 (Map2k2)
04919 Thyroid hormone signaling pathway
105990471 (Map2k2)
04916 Melanogenesis
105990471 (Map2k2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
105990471 (Map2k2)
09156 Nervous system
04720 Long-term potentiation
105990471 (Map2k2)
04730 Long-term depression
105990471 (Map2k2)
04722 Neurotrophin signaling pathway
105990471 (Map2k2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105990471 (Map2k2)
05206 MicroRNAs in cancer
105990471 (Map2k2)
05205 Proteoglycans in cancer
105990471 (Map2k2)
05207 Chemical carcinogenesis - receptor activation
105990471 (Map2k2)
05208 Chemical carcinogenesis - reactive oxygen species
105990471 (Map2k2)
05230 Central carbon metabolism in cancer
105990471 (Map2k2)
05231 Choline metabolism in cancer
105990471 (Map2k2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
105990471 (Map2k2)
09162 Cancer: specific types
05210 Colorectal cancer
105990471 (Map2k2)
05225 Hepatocellular carcinoma
105990471 (Map2k2)
05226 Gastric cancer
105990471 (Map2k2)
05214 Glioma
105990471 (Map2k2)
05216 Thyroid cancer
105990471 (Map2k2)
05221 Acute myeloid leukemia
105990471 (Map2k2)
05220 Chronic myeloid leukemia
105990471 (Map2k2)
05218 Melanoma
105990471 (Map2k2)
05211 Renal cell carcinoma
105990471 (Map2k2)
05219 Bladder cancer
105990471 (Map2k2)
05215 Prostate cancer
105990471 (Map2k2)
05213 Endometrial cancer
105990471 (Map2k2)
05224 Breast cancer
105990471 (Map2k2)
05223 Non-small cell lung cancer
105990471 (Map2k2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
105990471 (Map2k2)
05170 Human immunodeficiency virus 1 infection
105990471 (Map2k2)
05161 Hepatitis B
105990471 (Map2k2)
05160 Hepatitis C
105990471 (Map2k2)
05164 Influenza A
105990471 (Map2k2)
05163 Human cytomegalovirus infection
105990471 (Map2k2)
05167 Kaposi sarcoma-associated herpesvirus infection
105990471 (Map2k2)
05165 Human papillomavirus infection
105990471 (Map2k2)
09171 Infectious disease: bacterial
05132 Salmonella infection
105990471 (Map2k2)
05135 Yersinia infection
105990471 (Map2k2)
09164 Neurodegenerative disease
05010 Alzheimer disease
105990471 (Map2k2)
05022 Pathways of neurodegeneration - multiple diseases
105990471 (Map2k2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
105990471 (Map2k2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105990471 (Map2k2)
01522 Endocrine resistance
105990471 (Map2k2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dord01001
]
105990471 (Map2k2)
Enzymes [BR:
dord01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
2.7.12.2 mitogen-activated protein kinase kinase
105990471 (Map2k2)
Protein kinases [BR:
dord01001
]
Serine/threonine kinases: STE group
STE7 family
105990471 (Map2k2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
Haspin_kinase
CAMSAP_CC1
Kdo
Seadorna_VP7
APH
Motif
Other DBs
NCBI-GeneID:
105990471
NCBI-ProteinID:
XP_012878361
Ensembl:
ENSDORG00000001269
UniProt:
A0A1S3FP56
LinkDB
All DBs
Position
Unknown
AA seq
400 aa
AA seq
DB search
MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQ
GTHYSVQSDIWSMGLSLVELSIGRYPIPPPDAKELEAIFGRPVTDGAEGEPHSISPRPRP
PGRPVSGHGMDSRPTMAIFELLDYIVNEPPPKLPSGVFSPDFQEFVNKCLIKNPAERADL
KMLMNHSFIKRAEVEEVDFAGWLCRTLRLKQPSTPTRTAV
NT seq
1203 nt
NT seq
+upstream
nt +downstream
nt
atgctggcccggaggaagccggtgctgccggcgctcaccatcaaccccaccatcgccgag
ggcccgtcccccaccagcgagggcgcctccgaggcaaacctagtggacctgcagaagaag
ctggaggaactggaactagatgagcagcagaaaaagcgtctcgaggctttccttacccag
aaggccaaagtcggcgagctcaaggatgatgactttgaaagaatctcagaactgggagct
ggcaatggcggggtggtcaccaaggtccaacacagaccatcaggtcttatcatggccagg
aagctgatccacctggagatcaagccagctatccggaaccagatcatccgcgagctgcag
gtgctgcacgagtgcaactccccgtacatcgtgggcttttatggcgccttctacagcgac
ggggagatcagcatctgcatggagcacatggatggcggctccttggaccaggtgctgaaa
gaagccaagcggattccagaggagatcctggggaaggtcagcatcgcggtgctccggggc
ctggcctacctgcgggagaagcaccagatcatgcaccgagacgtgaagccttccaacatc
ctcgtcaactcccgaggggagatcaagctgtgtgacttcggggtgagcgggcagctcatt
gactccatggccaactcgttcgtgggcacccggtcctacatgtctccagaacggctgcag
ggcacccactactccgtgcagtcggacatctggagcatgggcctgtccctggtggagcta
tccatcgggaggtaccccattcccccgccggacgccaaggagctggaggccatctttggc
cggcccgtgacggacggggcggaaggagagccccacagcatctcaccacggcccagaccc
cctggacgccccgtcagcggtcacgggatggacagccggcccaccatggccatctttgag
ctgctggactacatcgtgaacgagccgcctcctaagctgcccagtggggtgttcagccca
gacttccaggagtttgtaaataaatgcctcattaagaacccagcagaacgagcggatctg
aagatgctcatgaaccactcgttcatcaagcgggccgaggtggaagaagtggactttgcg
ggctggctgtgccgaaccctgcggctgaagcagcccagcacgcccacgcgcacggccgtg
tga
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integrated database retrieval system
