Dipodomys ordii (Ord's kangaroo rat): 105992308
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Entry
105992308 CDS
T07834
Symbol
Ptk2
Name
(RefSeq) focal adhesion kinase 1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
dord
Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord01522
Endocrine resistance
dord04012
ErbB signaling pathway
dord04062
Chemokine signaling pathway
dord04148
Efferocytosis
dord04151
PI3K-Akt signaling pathway
dord04360
Axon guidance
dord04370
VEGF signaling pathway
dord04510
Focal adhesion
dord04670
Leukocyte transendothelial migration
dord04810
Regulation of actin cytoskeleton
dord04935
Growth hormone synthesis, secretion and action
dord05100
Bacterial invasion of epithelial cells
dord05135
Yersinia infection
dord05146
Amoebiasis
dord05163
Human cytomegalovirus infection
dord05165
Human papillomavirus infection
dord05170
Human immunodeficiency virus 1 infection
dord05200
Pathways in cancer
dord05202
Transcriptional misregulation in cancer
dord05205
Proteoglycans in cancer
dord05208
Chemical carcinogenesis - reactive oxygen species
dord05222
Small cell lung cancer
dord05417
Lipid and atherosclerosis
dord05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
dord00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
105992308 (Ptk2)
04370 VEGF signaling pathway
105992308 (Ptk2)
04151 PI3K-Akt signaling pathway
105992308 (Ptk2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
105992308 (Ptk2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
105992308 (Ptk2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
105992308 (Ptk2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
105992308 (Ptk2)
04062 Chemokine signaling pathway
105992308 (Ptk2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
105992308 (Ptk2)
09158 Development and regeneration
04360 Axon guidance
105992308 (Ptk2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105992308 (Ptk2)
05202 Transcriptional misregulation in cancer
105992308 (Ptk2)
05205 Proteoglycans in cancer
105992308 (Ptk2)
05208 Chemical carcinogenesis - reactive oxygen species
105992308 (Ptk2)
09162 Cancer: specific types
05222 Small cell lung cancer
105992308 (Ptk2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
105992308 (Ptk2)
05163 Human cytomegalovirus infection
105992308 (Ptk2)
05165 Human papillomavirus infection
105992308 (Ptk2)
09171 Infectious disease: bacterial
05135 Yersinia infection
105992308 (Ptk2)
05100 Bacterial invasion of epithelial cells
105992308 (Ptk2)
09174 Infectious disease: parasitic
05146 Amoebiasis
105992308 (Ptk2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105992308 (Ptk2)
05418 Fluid shear stress and atherosclerosis
105992308 (Ptk2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
105992308 (Ptk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dord01001
]
105992308 (Ptk2)
01009 Protein phosphatases and associated proteins [BR:
dord01009
]
105992308 (Ptk2)
Enzymes [BR:
dord01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
105992308 (Ptk2)
Protein kinases [BR:
dord01001
]
Non-receptor tyrosine kinases
FAK family
105992308 (Ptk2)
Protein phosphatases and associated proteins [BR:
dord01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
105992308 (Ptk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
105992308
NCBI-ProteinID:
XP_012880590
Ensembl:
ENSDORG00000014660
UniProt:
A0A1S3FW28
LinkDB
All DBs
Position
Unknown
AA seq
1007 aa
AA seq
DB search
MAAAYLDPNLNHTPSSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD
ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
LKFFEILSPVYRYDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQ
TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFII
RPQKEGERALPSIPKLANSEKQGVRTHTVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRE
RIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDH
PHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK
RFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFT
SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA
YDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGY
PSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTESWNHRPQE
ISMWQPNMEDSAVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLS
RGSIDREDGSLQGPLSCQLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPA
PPEEYVPMVKEVGLALRTLLATVDETIPGLPASTHREIEMAQKLLNSDLGELIGKMKLAQ
QYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKTLGQTRPH
NT seq
3024 nt
NT seq
+upstream
nt +downstream
nt
atggcagctgcttaccttgacccaaacttgaatcatacaccaagttcaagtactaagact
cacctgggtactggtatggaacgttctcctggtgcgatggagcgagtattaaaggtcttt
cattattttgaaagcaatagtgagccaaccacctgggccagtattattagacatggagat
gctactgatgtgaggggcatcattcagaagatagtggacagtcacaaggtaaagcatgtg
gcctgctatggattccgcctcagtcacctgcggtcggaggaggtacactggctccacgtg
gacatgggtgtctccagtgtgagggagaagtatgagctcgcccacccaccagaggagtgg
aagtatgaattaagaattcgttatttgccaaaaggatttctaaaccagtttactgaagac
aaaccaactctgaatttcttctaccaacaggtgaagagcgactacatgttagagatagct
gatcaggtggaccaggagattgctttgaagttgggttgtctagaaatacggcgatcatac
tgggagatgcgaggcaatgcgttagaaaagaagtctaactatgaagtattagaaaaagat
gttggcttaaagcgattttttcctaagagtttactggattctgtcaaggccaaaacatta
agaaaactgatacaacaaacatttagacaatttgccaaccttaatagagaagaaagtatt
ctgaaattctttgaaatcctttctccagtgtatcgatatgacaaagaatgtttcaagtgt
gctcttgggtcaagctggattatttcagtggaactggcaattggcccagaagaagggatc
agctacctgacagacaagggctgcaatcccacacatctggctgacttcaaccaagtgcag
acaattcagtattcaaacagtgaagacaaggacagaaaaggaatgctgcagctcaaaatc
gcaggtgcacctgagcctctgacagtgacggcaccatccctaactatcgcagagaacatg
gctgacctgatagatggctactgccggctggtgaatggagcaacacagtcctttatcatc
agaccccagaaagaaggtgaacgggcattgccatcaataccaaagttggccaacagcgaa
aagcaaggagttcgaacacacacagtctccgtgtcagagacagatgattatgctgagatc
attgatgaagaagacacctacacaatgccctcaacgagggattatgagatccaaagagaa
agaatagaacttggacgatgtattggagaaggccagtttggagatgtacatcaaggagtg
tatatgagtccggagaacccagctttggcagttgcaattaaaacgtgtaagaactgtact
tcggacagcgtgagagagaaattccttcaagaagccttaacaatgcgtcagtttgaccat
cctcatattgtgaagctgattggagtcatcacagagaatcctgtctggataatcatggag
ctgtgcaccctgggagagctgagatcatttttgcaagtaaggaagtacagcttggatctg
gcgtctttgatcctgtatgcttatcaacttagtacagcacttgcgtatctggagagcaaa
agatttgtacacagggacattgctgctcggaatgttctggtatcctcaaatgattgtgta
aaattaggagactttggcttatcgcgttatatggaagacagtacttattacaaagcttca
aaaggaaaattgcctataaaatggatggctccagagtcaatcaattttcgacggtttacc
tcagctagtgacgtatggatgtttggtgtatgtatgtgggagatactgatgcatggtgtg
aagccctttcaaggagtgaagaacaatgatgtgatcggtcgaattgaaaatggggaaaga
ttaccaatgcctccaaattgtcctcctaccctctacagccttatgacgaaatgctgggct
tatgaccccagcaggcggcccaggtttactgaacttaaagctcagctcagcacaatcctg
gaagaggaaaaagctcagcaagaagaacgaatgaggatggaatccagaagacaggccacc
gtgtcttgggactctggagggtctgatgaagcaccgcccaagcccagtaggcctggttat
cctagtccaagatccagtgaaggattttaccccagccctcagcacatggtacagaccaat
cattatcaggtctctggctaccctggttcacatggaatcacagccatggccggcagcatc
tacccaggccaagcatctcttctggaccagacagagtcatggaatcatagacctcaagag
atatccatgtggcagcccaacatggaggactcagcagtcttggacctgcgaggcatcggg
caagtgctacccacccacctgatggaagagcggttgatccgacagcagcaggaaatggaa
gaagatcaacgctggctggaaaaagaggagagatttctgaaacctgacgtgaggctctcc
cgaggcagtatcgaccgggaagacgggagtcttcagggcccattgtcttgtcagcttcag
ccccaggaaatcagtccccctcccactgccaacctggacaggtccaatgacaaggtatat
gagaacgtgacgggcctggtgaaagccgtgattgagatgtccagcaaaatccagccagcc
ccaccggaggagtacgtccccatggtgaaggaggttggcttggccctgcggacattactg
gccactgtggatgaaaccattcctggcctgccagccagcacgcaccgagagattgagatg
gcgcagaagctgctcaactccgacctgggcgagctcattggcaagatgaagctggcacag
caatatgtcatgaccagcctgcagcaggagtacaagaagcagatgctgacggctgcccac
gccctggctgtggatgccaagaacctgctggatgtcattgaccaagcgaggctgaaaacg
ctaggacagacgaggcctcactga
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integrated database retrieval system
