Dipodomys ordii (Ord's kangaroo rat): 105994705 Help Entry 105994705         CDS       T07834                                  Symbol Jak3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism dord  Dipodomys ordii (Ord's kangaroo rat) Pathway dord04062   Chemokine signaling pathway dord04151   PI3K-Akt signaling pathway dord04217   Necroptosis dord04550   Signaling pathways regulating pluripotency of stem cells dord04630   JAK-STAT signaling pathway dord04658   Th1 and Th2 cell differentiation dord04659   Th17 cell differentiation dord05161   Hepatitis B dord05162   Measles dord05166   Human T-cell leukemia virus 1 infection dord05169   Epstein-Barr virus infection dord05200   Pathways in cancer dord05203   Viral carcinogenesis dord05223   Non-small cell lung cancer dord05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:dord00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     105994705 (Jak3)    04151 PI3K-Akt signaling pathway     105994705 (Jak3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     105994705 (Jak3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     105994705 (Jak3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     105994705 (Jak3)    04659 Th17 cell differentiation     105994705 (Jak3)    04062 Chemokine signaling pathway     105994705 (Jak3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105994705 (Jak3)    05203 Viral carcinogenesis     105994705 (Jak3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     105994705 (Jak3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105994705 (Jak3)    05161 Hepatitis B     105994705 (Jak3)    05162 Measles     105994705 (Jak3)    05169 Epstein-Barr virus infection     105994705 (Jak3)   09163 Immune disease    05340 Primary immunodeficiency     105994705 (Jak3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:dord01001]     105994705 (Jak3) Enzymes [BR:dord01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      105994705 (Jak3) Protein kinases [BR:dord01001]  Non-receptor tyrosine kinases   JAK family [OT]    105994705 (Jak3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 Jak1_Phl SH2_1 FERM_C_FAK1 ABC1 LRR_RI_capping Haspin_kinase Motif Other DBs NCBI-GeneID:  105994705 NCBI-ProteinID:  XP_012883788 UniProt:  A0A1S3G4P2 LinkDB All DBs Position Unknown AA seq 1272 aa AA seqDB search MAPLSEETPLISQRSCSLSSSEAGALDVLLPALGPGPPQRLSFSFGELSAEELCVQAAKA SGILPVYHPLFALATEDLSYWFPPSHIFSVEDAGTQVLVYRLRFHFPNWFGLEKCHRFGL RKDLAGAVFDLRVLEHLFAQHRGDLVAGRLAVGLGLRDQGECLSLAVLDLARLCRERAQR PRELLRTVSYKACLPPGLRGLIQGLSFVTRKRIRRTVRRALRRVAASQADRHSLLAKYIM DLERLDPARHAETFRVGLPGPAGDQGAPGLLRVAGGSGIAWSAGEAEDFQPFCDFPEVVD ISVKQAPGAGEHRLVTLTRTDKQMLEAEFPGLPEALSFVALVDGYFRLTCDPHHFFCKEA APPRLLEEAAWGCCGPITLDFAIHKLKAAGALPGSFVLRRSPQDFHSVLLTVCVQGPLVS TGAARSSRTHIGFPPSPSSVEKSNLVVVRGGYGLAPQACAAPRGPRKPGPMTFHTIPAHS LQRHENLGHGSFTKIYRGLRHEAVDGEARETEVLLKVMDATHRHCMESFLEAASLMSQVS YPHLVLLHGVCMAGDSTMVQEFVPLGAVDTYLLKRGQQVPASWKLQVIKQLAYALSYLED KELPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQCPR EPQALGLEADKWGFGATAWEVFSGAPMPVSALEPAEKLRFYEQRQQLPPPKWTELASLIQ DCMAYEPGRRPSFRAVIRDLNSLTTSDYELLADPTAGGLEPRDGLWSSARLYACQDPTIF EERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKA MHSDYIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLRRHRARLDAGRLLLYASQICKGM EYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPE SLADSVFSRQSDVWSFGVLLYELFTYGDKSCSPSAVSGQGPLVKSLISFAGRGPGASPGA GGDALAPTLTPFLSSSRPLPSPPGRARWGAGRGLRLGGPCGRLRTVGDPRQRRTRLRRMN GTFGLQQERQQHAEPSRPASVALNDPVNIHEPKAAAFWAPTGPWGTGFSPEHSGAIRPSA KVGTKPAPPPADPALSPAKPRAGTLRAANPAPAPRVPLPGSAPARGHSPRDVPPLRLPGA VRKFSPGPSPRLPPAPSFLQPSHLLPALAARGPPSSRAAELRVPDWLTAPRPRPTHSMLS PYGPAPKAPPLS NT seq 3819 nt NT seq  +upstreamnt  +downstreamnt atggcgcctctgagcgaggagacccccctcatctcccagcgctcctgcagcctgtcctcc tcagaggccggggccttggatgtgctgctcccagctctgggccctgggcctcctcagcgc ctctccttctcctttggggagctatctgcagaggagttgtgtgtgcaggctgccaaggcc agcggcatcctgcccgtgtatcacccactctttgccctggccactgaggacctctcctac tggttccccccaagccacatcttctccgtggaggacgcaggcacccaagtcttggtctac aggctgcgcttccatttccccaactggttcgggctggagaaatgccaccggtttgggctg cgcaaggacctggctggcgccgtcttcgacttgcgggtcctggaacacctcttcgcccag caccgcggggacctggtggccgggcgcctggccgtcggcctgggcctccgggaccagggg gagtgcctcagcctggcggtgctggacctggcccggctgtgccgcgagcgggcgcagcgg ccccgggagctgctgaggacggtgagctacaaggcctgcctgccgcccggcctgcgcggc ctcatccagggcctcagtttcgtcacccgcaagcgcatccgcaggaccgtgcgccgcgcg ctgcgccgcgtggccgccagccaggccgaccggcactcgctcctggccaagtacatcatg gacctggagcggctggacccggcccggcacgccgagaccttccgcgtggggctcccgggg cccgcgggggaccagggcgcgccggggctgctgcgcgtggccggcggcagcggcatcgcc tggagcgcgggagaggctgaggacttccagcccttctgtgactttccggaggtggtggac atcagcgtgaagcaggcgcccggggcgggcgagcaccgcctggtgaccctcaccaggacg gacaagcagatgctggaggccgagttcccggggctgcccgaggcgctgtccttcgtggcc ctggtggatggctacttccgcctcacctgcgacccgcaccacttcttctgcaaggaggcg gcgccgccgcggctgctggaggaggcggcgtggggctgctgcgggcccatcacgctggac ttcgccatccacaaactcaaggccgcgggggccctgcccggctccttcgtcctccgccgc agcccccaggacttccacagcgtcctgctcacggtctgcgtgcagggcccgctggtctcc acaggagcggcccgcagctcccgcacccacatcggtttcccgccctctccctcctctgta gagaagtccaacctggtggtggtgcggggcgggtacggcctggccccgcaggcctgcgcc gcaccccgtggcccccgcaagccgggccccatgaccttccacaccatcccggcccacagc ctgcagcggcacgagaacctgggccacgggtccttcaccaagatctaccggggcctccgc cacgaggccgtggacggggaggcccgcgagaccgaggtgctgctgaaggtgatggacgcc acgcacaggcactgcatggagtccttcctggaagctgccagcctgatgagccaggtctcc tacccgcatctggtgctgctgcacggcgtgtgcatggctggcgacagcaccatggtgcag gaatttgtccccctgggagccgtggacacgtacctgctcaagcgtggccagcaggtgccg gccagctggaagctgcaggtcatcaaacagctggcctacgccctcagctacctggaggac aaagagctgcctcacggcaacgtgtccgcgcggaaggtgctgctggctcgggaaggggcc gacgggagcccccctttcatcaagctgagcgaccccggggtcagccccacagtgctcagc ctggaaatgctcaccgacaggatcccctgggtggcccccgagtgcctgcagtgcccccgg gagccgcaggccctgggcctggaagccgacaagtggggcttcggcgccacggcctgggag gtgttcagtggcgccccgatgcccgtcagcgcgctggagcccgccgagaaactcaggttc tacgagcagcggcagcagctgccgccgcccaagtggacagagctggcctcgctgatccag gactgcatggcctacgagccgggccggcggccctccttccgggctgtcatccgggaccta aacagcctcaccacgtcagactacgagctgctcgcagaccccacagccggcggcctggag cctcgagatgggctctggagcagcgcccgactctacgcctgccaggaccccacgatcttc gaggagagacacctcaaatacatctcacagctgggcaagggcaacttcggcagcgtggag ctgtgccgctatgacccgctgggagacaacaccggcgccctggtggctgtgaagcagctg cagcacagcggcccggaccagcagagggacttccagcgcgagatccagattcttaaagcc atgcacagcgactacatcgtcaagtaccgcggcgtcagttacggcccaggccgccagagc ctgcgtctggtcatggagtacctgcccagcggctgcctgcgcgacttcctgcgccgccac cgcgcccgcctcgacgcggggcgcctcctgctctatgcctcgcagatctgcaagggcatg gagtacctgggctcccgccgctgcgtgcaccgcgacctggccgcgcgcaacatcctggtg gagagcgaggcgcacgtgaagatcgccgacttcggcctcgccaagctgctgccgctcgac aaagactactacgtggtccgcgagcccggccagagccccatcttctggtacgcgcccgag tccctggcggacagcgtcttctcacgccagtccgacgtctggagcttcggggtcctgctg tacgagctgttcacctacggcgacaagagctgcagcccctcggctgtgagtgggcagggg cccctcgtgaaaagcctcatttcttttgctggccggggcccaggagcctccccaggcgca ggtggcgacgccctggccccgaccctcaccccattcctctccagctccaggcccctgccc agcccgccgggccgcgcccgctggggcgccgggcggggcctgaggttgggaggcccctgc ggccggctgaggacggtgggggaccccaggcagcgccggacgcggctccgccggatgaac gggacgttcgggcttcaacaggaacgccagcaacacgcggaaccttctagacctgcctcg gtggcccttaatgaccctgtgaatattcatgagcccaaggccgccgccttctgggcccca acgggcccctggggcactggcttcagccccgaacattccggagccatccgaccttctgcc aaagttgggacgaagccggccccgccgcccgcagaccccgccctgagccccgccaagccc cgggccgggacgctccgcgccgcgaaccccgcgccggccccccgagtcccgctccccggc tccgctcccgcccgcggccactcaccacgcgacgtcccgcctctgaggctcccgggagcg gtcagaaagttttcacctggaccgagcccccgcctcccgccggctccttccttcctgcag ccctcccacctcctgcccgccctcgccgcccgcgggcctccttccagccgcgccgcggag ctccgagtcccggactggcttaccgcgccacgcccccggcccacccactccatgctgtct ccctacggccctgccccgaaagccccgcccctctcatag

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