KEGG   DRUG: ヒドララジン塩酸塩
エントリ  
D01302                      Drug                                   
一般名   
ヒドララジン塩酸塩 (JP18);
Hydralazine hydrochloride (JP18/USP)
商品名   
米国の商品 
  後発品
HYDRALAZINE (Nivagen Pharmaceuticals), HYDRALAZINE HCL (DirectRX), HYDRALAZINE HYDROCHLORIDE (A-S Medication Solutions), HYDRALAZINE HYDROCHLORIDE (A-S Medication Solutions), HYDRALAZINE HYDROCHLORIDE (A-S Medication Solutions), HYDRALAZINE HYDROCHLORIDE (A-S Medication Solutions), HYDRALAZINE HYDROCHLORIDE (American Health Packaging), HYDRALAZINE HYDROCHLORIDE (American Health Packaging), HYDRALAZINE HYDROCHLORIDE (American Health Packaging), HYDRALAZINE HYDROCHLORIDE (American Regent), HYDRALAZINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), HYDRALAZINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), HYDRALAZINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), HYDRALAZINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), HYDRALAZINE HYDROCHLORIDE (Ascend Laboratories), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Bryant Ranch Prepack), HYDRALAZINE HYDROCHLORIDE (Cadila Pharmaceuticals Limited), HYDRALAZINE HYDROCHLORIDE (Camber Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (Cardinal Health 107), HYDRALAZINE HYDROCHLORIDE (Cardinal Health 107), HYDRALAZINE HYDROCHLORIDE (Cardinal Health 107), HYDRALAZINE HYDROCHLORIDE (Cardinal Health 107), HYDRALAZINE HYDROCHLORIDE (Cardinal Health 107), HYDRALAZINE HYDROCHLORIDE (Chartwell RX), HYDRALAZINE HYDROCHLORIDE (Civica), HYDRALAZINE HYDROCHLORIDE (Denton Pharma), HYDRALAZINE HYDROCHLORIDE (Direct_Rx), HYDRALAZINE HYDROCHLORIDE (Eugia US LLC), HYDRALAZINE HYDROCHLORIDE (Exelan Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (Fresenius Kabi USA), HYDRALAZINE HYDROCHLORIDE (Fresenius Kabi USA), HYDRALAZINE HYDROCHLORIDE (Fresenius Kabi USA), HYDRALAZINE HYDROCHLORIDE (Glenmark Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (HF Acquisition Co LLC), HYDRALAZINE HYDROCHLORIDE (HF Acquisition Co LLC), HYDRALAZINE HYDROCHLORIDE (HF Acquisition Co LLC), HYDRALAZINE HYDROCHLORIDE (Henry Schein), HYDRALAZINE HYDROCHLORIDE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (Hikma Pharmaceuticals USA), HYDRALAZINE HYDROCHLORIDE (Macleods Pharmaceuticals Limited), HYDRALAZINE HYDROCHLORIDE (Major Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (McKesson Corporation dba SKY Packaging), HYDRALAZINE HYDROCHLORIDE (McKesson Corporation dba SKY Packaging), HYDRALAZINE HYDROCHLORIDE (Medical Purchasing Solutions), HYDRALAZINE HYDROCHLORIDE (Medical Purchasing Solutions), HYDRALAZINE HYDROCHLORIDE (Medical Purchasing Solutions), HYDRALAZINE HYDROCHLORIDE (Medical Purchasing Solutions), HYDRALAZINE HYDROCHLORIDE (Modavar Pharmaceuticals LLC), HYDRALAZINE HYDROCHLORIDE (Mylan Institutional), HYDRALAZINE HYDROCHLORIDE (NCS HealthCare of KY), HYDRALAZINE HYDROCHLORIDE (Northwind Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (Northwind Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (Northwind Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (NuCare Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (NuCare Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (NuCare Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (NuCare Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (Preferred Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (Preferred Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (Proficient Rx LP), HYDRALAZINE HYDROCHLORIDE (Proficient Rx LP), HYDRALAZINE HYDROCHLORIDE (Proficient Rx LP), HYDRALAZINE HYDROCHLORIDE (Proficient Rx LP), HYDRALAZINE HYDROCHLORIDE (REMEDYREPACK), HYDRALAZINE HYDROCHLORIDE (REMEDYREPACK), HYDRALAZINE HYDROCHLORIDE (REMEDYREPACK), HYDRALAZINE HYDROCHLORIDE (REMEDYREPACK), HYDRALAZINE HYDROCHLORIDE (REMEDYREPACK), HYDRALAZINE HYDROCHLORIDE (REMEDYREPACK), HYDRALAZINE HYDROCHLORIDE (REMEDYREPACK), HYDRALAZINE HYDROCHLORIDE (REMEDYREPACK), HYDRALAZINE HYDROCHLORIDE (Radha Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (ScieGen Pharmaceuticals), HYDRALAZINE HYDROCHLORIDE (Strides Pharma Science Limited), HYDRALAZINE HYDROCHLORIDE (Teva Pharmaceuticals USA)
組成式   
C8H8N4. HCl
質量    
196.0516
分子量   
196.64
構造式   
Simcomp   
クラス   
心血管系用薬
 DG03231  血圧降下薬
 DG02046  ヒドラジノフタラジン誘導体
代謝酵素基質薬
 DG02928  NAT基質薬
代謝酵素阻害薬
 DG01645  CYP2D6阻害薬
コード   
薬効分類: 2142
ATCコード: C02DB02
化学構造グループ: DG00261
商品 (DG00261): D01302<JP/US>
商品 (mixture): D10209<US>
効能    
血圧降下薬
  疾患
本態性高血圧症 [DS:H01633]
妊娠高血圧症候群 [DS:H00603]
高血圧性緊急症 [DS:H01633]
コメント  
ヒドラジノフタラジン誘導体
末梢血管直接作用性降圧薬
代謝    
Enzyme: NAT [HSA:9 10]
相互作用  
CYP inhibition: CYP2D6 [HSA:1565]

階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  21  循環器官用薬
   214  血圧降下剤
    2142  ヒドララジン製剤
     D01302  ヒドララジン塩酸塩 (JP18)
医療用医薬品のATC分類 [BR:jp08303]
 C 循環器系
  C02 降圧薬
   C02D 細動脈平滑筋作用薬
    C02DB ヒドラジノフタラジン誘導体
     C02DB02 ヒドララジン
      D01302  ヒドララジン塩酸塩 (JP18) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 心血管治療薬
  血管拡張薬
   動脈直接作用型血管拡張薬
    ヒドララジン
     D01302  ヒドララジン塩酸塩 (JP18)
医薬品グループ [BR:jp08330]
 心血管系用薬
  DG03231  血圧降下薬
   DG00261  ヒドララジン
    D01302  ヒドララジン塩酸塩
  DG02046  ヒドラジノフタラジン誘導体
   DG00261  ヒドララジン
    D01302  ヒドララジン塩酸塩
 代謝酵素基質薬
  DG02928  NAT基質薬
   DG00261  ヒドララジン
    D01302  ヒドララジン塩酸塩
 代謝酵素阻害薬
  DG01645  CYP2D6阻害薬
   DG00261  ヒドララジン
    D01302  ヒドララジン塩酸塩
医薬品クラス [BR:jp08332]
 心血管系用薬
  DG03231  血圧降下薬 [商品一覧]
   D01302  ヒドララジン塩酸塩
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D01302  ヒドララジン塩酸塩
  D01302  ヒドララジン塩酸塩錠
  D01302  ヒドララジン塩酸塩散
  D01302  注射用ヒドララジン塩酸塩
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D01302
医薬品グループ [BR:jp08330]
 心血管系用薬
  DG03231  血圧降下薬
   DG00261  ヒドララジン
  DG02046  ヒドラジノフタラジン誘導体
   DG00261  ヒドララジン
 代謝酵素基質薬
  DG02928  NAT基質薬
   DG00261  ヒドララジン
 代謝酵素阻害薬
  DG01645  CYP2D6阻害薬
   DG00261  ヒドララジン
リンク   
CAS: 304-20-1
PubChem: 7848365
ChEBI: 31672
LigandBox: D01302
日化辞: J257.318K
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