Danio rerio (zebrafish): 30280 Help Entry 30280             CDS       T01004                                  Symbol jak1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism dre  Danio rerio (zebrafish) Pathway dre04217   Necroptosis dre04620   Toll-like receptor signaling pathway dre04621   NOD-like receptor signaling pathway dre05168   Herpes simplex virus 1 infection Brite KEGG Orthology (KO) [BR:dre00001]  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     30280 (jak1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     30280 (jak1)    04621 NOD-like receptor signaling pathway     30280 (jak1)  09160 Human Diseases   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     30280 (jak1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:dre01001]     30280 (jak1) Enzymes [BR:dre01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      30280 (jak1) Protein kinases [BR:dre01001]  Non-receptor tyrosine kinases   JAK family [OT]    30280 (jak1) SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 Jak1_Phl SH2_1 FERM_F1 ABC1 SH2 Motif Other DBs NCBI-GeneID:  30280 NCBI-ProteinID:  NP_571148 ZFIN:  ZDB-GENE-980526-142 Ensembl:  ENSDARG00000020625 UniProt:  A0A8N7V0P0 Q7ZU16 LinkDB All DBs Position 6:33883851..33942171 Genome browser AA seq 1153 aa AA seqDB search MPELAVMDLGRQLCVKMKKQRKAEMTIPTAMKGLEIHFYLADTHQLEFFKACYTAEDLCV EAAKRCRISPLCHNLFALYEESQDLWYAPNHVFKVTDETSIKLHYRMRFYFTNWHGTSEI ESPVWRHTLSKQKSVLNSQKTTEGTPLLDAASLDYLFAQGQYDFLRGLSPVRPTQNDEEH REIENECLGMAVLAITHHAKSNNLPLSGAGAETSYKRFIPDSLNRTIKQRNFLTRIRISN VFKNFLNEFNSKTIQDSNIGLYDLKVKYLSTLETLTQGVGREIFKPKNLKVTGESEGSPA QMLPLGDNGMGYEVQVYGTTGISWRRKPAPNQLILKDKPKSKKIKGDKQWNDKKKDSGWT LFSDFHEITHIVIKDCCVTIYRQDNKTMELDLFYRDAALSFAALVDGYFRLTVDAHHYLC TDVAPSSVVQNLENGCHGPICTEYAIHKLRQEGNEEGTYVLRWSCTEYNFIIMTVVCIEL DLCESRPVPQYKNFQIETSPQGYRLYGTDTFRPTLKELLEHLQGQLLRTDNLRFQLRRCC PPQPREISNLLVMTTDREPVPQKKTQVSQLSFDRILKEEIVQGEHLGRGTRTNIYAGILK PKSDDEDDLGGYSQEVKVVLKVLGSGHRDISLAFFETASMMRQISHKHIALLYGVCVRHQ ENIMVEEFVQYGPLDLFMRRQTTPLSTAWKFQVAKQLASALSYLEDKKMVHGYVCSKNIL VARDGLDGEGGPFIKLSDPGIPITVLSREECVDRIPWIAPECVKDTANLSIAADKWSFGT TLWEICYNGEIPLKDKKLTEKERFYAAQCQLATPDCDELAKLMTHCMTYDPRQRLFFRAI VRDIVMVEKQNPSIQPVPMLEVDPTVFEKRFLKKIRDLGEGHFGKVELCRYDPRGDRTGE LVAVKSLKPENREEQSNNLWREIHILRELYHENIVKYKGICNEEGGRSIKLIMEFLPAGS LKEYLPRNKAHINLKTLLNYSVQICQGMDYLGSRNYIHRDLAARNVLVENEGTVKIGDFG LTKSIKDNEGYYTVKDDLDSPVFWYAPECLIHCKFYRASDVWSFGVTMYELLTYCDASCS PMSVFLKLIGPTHGQMTVTRLVKVLEEGKRLPRPDDCSEQLYNLMRRCWEATPEKRINFK SLIANFQQMLDNQ NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgccagaactagcagtcatggatctgggcaggcaactgtgtgtgaagatgaaaaaacag aggaaggcagagatgaccattcctactgccatgaagggacttgagatccacttctacctt gctgacacacaccagctcgagttcttcaaagcctgctacactgcggaagacctgtgcgtg gaggctgccaagagatgccgcatctcacctttgtgccacaacctgtttgcactctatgaa gaaagccaggatctctggtatgctccaaatcacgtgttcaaggtcacagatgagaccagc atcaaacttcattatcgcatgaggttttatttcacaaactggcatggaaccagtgagatt gagtctccagtttggagacacacactcagcaaacagaaaagtgtattaaacagtcagaag accaccgagggaacacctctactagatgccgcatctcttgattacctgtttgcgcagggc cagtatgatttcctgagaggtctgtctcctgttcgtccaactcagaatgatgaagagcat catgagattgagaacgagtgcttgggaatggctgttttagctattacccatcatgccaag agcaataatttgccattatcaggagctggagccgagacaagctataagcgcttcattcca gatagtctgaaccgcaccattaagcaacgcaacttcctcacacgcatacgcatcagtaac gtcttcaagaatttcctcaatgagttcaatagcaagaccatccaggacagcaatataggt ctgtatgacctgaaggtcaagtatttgtccactctcgagacgctgactcaaggagtgggt agggagattttcaagcccaagaacctaaaagtaacgggtgagagtgagggatccccagca cagatgcttcccttgggggacaacggaatgggttatgaggtgcaagtatacggaactact gggatctcatggaggagaaagcccgcaccgaatcaattgatattgaaagacaaacccaaa tctaaaaagatcaagggcgacaagcagtggaatgacaaaaagaaagacagcggatggacg cttttctccgactttcatgaaataacccacatcgtcattaaggactgctgtgtcaccatt tacagacaagacaataaaaccatggagttggatctgttttatcgtgatgcagccctgtct tttgctgcactggtggacggttacttcagattgactgtggatgcccatcattacctgtgc actgatgtcgccccctcatcggtagtccagaatttagaaaacggctgtcacggacctatc tgcacagagtatgccattcataaacttcgacaggagggaaatgaagaaggaacctatgtg ctgcgctggagctgcacagaatacaactttattatcatgacggttgtctgcattgagctc gacctgtgtgaatccagaccagttccccagtataagaacttccagattgaaacgagccct cagggctacagactgtatgggacagacacattcagacccactctgaaggagctgctggag cacctgcagggccagttactgcgcaccgacaatctgcgcttccagctgcgccgctgctgc ccaccacaacccagagaaatttctaacctattagtgatgaccacagaccgagagcctgtc ccgcagaaaaaaactcaagtcagccagctgagtttcgaccgcattcttaaagaggagatt gtacagggtgaacatttgggtcgaggcacaaggacaaacatctatgctggtattctgaag ccgaagagtgatgatgaagatgatctgggaggatactcgcaggaggtgaaagtggttttg aaggtgctgggctcaggacatagagatatttctctggcattctttgagaccgctagcatg atgcgtcagatctctcacaaacacatcgccctgctctacggagtgtgtgtgcgtcaccag gagaatatcatggtggaggagtttgttcagtacggccctttggatctgttcatgcgcagg cagaccacacctctgagcactgcatggaagttccaggttgccaagcagttagccagtgcc ctcagctatctggaggataagaagatggtccatggatatgtgtgcagtaagaacattctg gtagctcgagatggtttagatggagaaggaggacccttcatcaagctgagtgaccccggg atacccattactgtcctcagcagagaagagtgtgtggacaggattccttggattgctcca gagtgtgtgaaagacacagctaatctgagcatagcggctgataagtggagtttcgggaca actctttgggagatatgttacaacggagagattcctctgaaagataagaaactcactgag aaggagaggttttacgcagcgcagtgtcagttggcaacccctgactgtgatgagctggcc aaactcatgacccactgcatgacttacgacccccgacagaggctcttcttcagggccatc gtcagggacattgttatggtggagaaacagaatccatccattcagcctgttcccatgctt gaagtggacccgacagtgtttgagaagaggttcctcaagaagattcgagaccttggagag ggtcattttgggaaggtggagttgtgccggtatgacccacgtggagatcggactggagag ctagtggctgtgaagtctctgaagccagagaaccgcgaagagcagagcaataacctgtgg cgtgagattcacatcctgagagaactttaccatgagaatatcgtcaaatacaagggcatc tgcaatgaagagggtgggagatccattaagctcatcatggagtttttgcctgcaggcagt ctaaaggaatacctccccagaaacaaggctcacataaaccttaaaactctgctcaactat tctgtgcagatctgccagggtatggactacctgggatctcgcaactacatccacagagac ctggcagcccgcaatgttctggtggagaatgaaggcacggtaaagattggagacttcggc ctgaccaaaagcattaaggataacgagggatactacactgtgaaagacgatctggacagt ccagtgttctggtatgctccagaatgtttgatccactgcaagttctacagggcatctgat gtctggtcttttggagtgaccatgtatgagctcctcacgtactgtgatgcttcatgtagc cccatgtcggtgttccttaagttgattggtccaacacatggacaaatgactgtcacccga ttggtcaaagtcctggaggagggaaagagacttccaagaccagatgactgctcagagcag ttgtacaacctgatgaggagatgctgggaagcaacacccgaaaaaaggatcgacttcaaa agcctgattgccaactttcagcagatgcttgacaatctgtaa

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