KEGG   Danio rerio (zebrafish): 337167
Entry
337167            CDS       T01004                                 
Symbol
tsc1a
Name
(RefSeq) TSC complex subunit 1a
  KO
K07206  tuberous sclerosis 1
Organism
dre  Danio rerio (zebrafish)
Pathway
dre04140  Autophagy - animal
dre04150  mTOR signaling pathway
dre04218  Cellular senescence
dre04910  Insulin signaling pathway
dre05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:dre00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    337167 (tsc1a)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    337167 (tsc1a)
  09143 Cell growth and death
   04218 Cellular senescence
    337167 (tsc1a)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    337167 (tsc1a)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    337167 (tsc1a)
SSDB
Motif
Pfam: Hamartin
Other DBs
NCBI-GeneID: 337167
NCBI-ProteinID: NP_956346
ZFIN: ZDB-GENE-030131-9111
Ensembl: ENSDARG00000026048
UniProt: Q7SXZ2
LinkDB
Position
5:29652468..29668982
AA seq 1128 aa
MAKEQPSVFDLIPLLGSTDLHELEQVKTLLQETLSADKGTMLLNSLVDYFLQTNSSQAVD
ILSSVREPHDKYLLDKMNECMGKQSCRLSTITLLGHVVRKQPPWIHKIARFPLLVSLLKC
LKTDSDVVVLITGVLVLITLMPMIPQTNKQLLCDYFDIFGRLAAWNQRHPGHAQGVFAVH
LHASVYSLFHRLYGMYPCNFVSYLRAYYSMKENVDTFEEVVKPMLEHVRIHPELITGTKD
YEVDPIRWKRFEPHDIVIECAKISLDSKEASSEEGYSSLADHIQRRAVHHSQSCSELSFH
EISSVTPIGAICQSLSKSQPYLTVTQDSGSSAQTPNNQSDEVKSSGMKEELWSPSSICGM
STPPSSRGMSPTTVSDISLSASHLSGRIPSTPGDGKWTLSPSTPSGSSPLPSLSEEIGQA
AQNTSSTQAKTCEEVKKVTSRSINNSSENGGDAKTPVSLAQLSDIVKRTEGEREDDTINE
EILSLTHGKLDFGSRPGLESSFSGSLDTLLSSHPNHEQNLVSTPDRVECSAKAGEHQLPR
SLWPFTPIENGKHSKCSLSDLTKESMPYEPLFDLALPKVASLFLERKTAEAFRRVEGERD
HQDEMEGEDLSVTSPLEVLDRVIQQGHDTHGKVLKRTFSSPSQSSDPHLKGLVPAVSDEL
DMLRSQLLLLHNQLLYERHKREQHALRNRRLFGRIVNTTALEEQNNSMKTQLKLQEVEIQ
AVKVSLKEEQRRSVHIQEDREAVVNQLQTQIQQLQKERNDYYSKMQVLKSELQENQTKAG
KMEAELQKANNKVCNMGHMLSQLSIKLNNSENMEQQMAFLNKQLLLLGEANKLYMEEIDR
LGPEAHKELNMLQASSVREGERLRQSSLQQSQRLEAAQQRITDLENQLTKKEQVIREQKK
LLDNVKRQATEQLQASENRYLAQKNITQALQTELLELYSKIELKNLKTNAPAEPISDPSS
PTNQRPNGNSAGPSAPSLPADLMKREEGAHVCVNGEISAASPQTPTALINGSQEEDLSAL
THSFPSLPCQPFAVGSYPSTRSFLGKKAREMFRNKSESHYDGDSPTLTCLSKDLKVEPIT
DPTESLESEEAADQFDLQPMDRPRAYNVQSRRHQDLRIMDYNETHHVH
NT seq 3387 nt   +upstreamnt  +downstreamnt
atggccaaagagcagccaagtgtgtttgacctcatccctcttctggggtccactgaccta
catgagctggaacaggtcaaaaccctgctgcaggaaactctcagtgcagataaagggacc
atgttgctgaatagccttgtagactatttccttcagacaaactcatctcaagctgtggac
atcctgtcttctgtccgggagcctcatgataagtatcttttagataagatgaatgaatgc
atgggcaagcagagctgtcgtctctccaccatcaccctccttggtcatgttgttcgcaaa
cagccaccatggatccacaagatcgcacgcttccctctgcttgtctcactgctcaaatgc
ctcaagactgactcagatgtagtagttctcataaccggtgtgctggtgctgatcactcta
atgcccatgattcctcaaaccaacaaacaacttctttgcgactactttgatatctttgga
cgtcttgctgcctggaaccaacgtcatccaggccatgctcagggagtgtttgcagtccat
ctacatgccagcgtgtactctcttttccatcgtttatatggcatgtatccttgtaatttc
gtttcgtacctgcgtgcctattacagtatgaaggaaaatgttgacacgttcgaggaagtg
gtgaagcccatgttggaacatgttcggatacatcctgagctcatcactggaaccaaagac
tacgaggttgatccaattagatggaagagatttgagccacatgatattgtgattgaatgt
gccaaaatttcactggattctaaagaggcatcatctgaagagggctactcctctttggcg
gatcacatacagcgacgcgctgtacaccatagccaatcatgttcagagctcagtttccat
gaaatctcatcagtcacaccaataggtgctatttgtcagtctctctctaaatcacaacct
tatctcactgtaacccaagactcaggttccagcgcacagacccccaacaatcaaagtgat
gaggtcaaatcctcagggatgaaggaggagctgtggagcccttcctcgatatgtgggatg
agcacccctcccagttctagaggaatgtccccaaccacagtttctgacatctcacttagt
gcctcacacctctcaggacggatccccagcaccccaggggatggaaagtggactctatct
ccctccacaccctcggggtcatcccctctcccatcgctctcagaggaaatagggcaggct
gcccaaaacaccagcagtacccaggctaagacgtgcgaagaggtgaagaaagtcacatcc
agaagtattaataacagcagtgagaatggaggtgatgccaagactccagtgtcgttggca
cagctctctgacattgtcaaaaggacagagggggagcgagaggatgatacaatcaatgag
gagattttaagtctaacacatgggaaactagactttggatctaggcctggtctggaatcc
tcattttctggctccttagacacccttctctcatctcatcccaaccatgagcagaatttg
gtatccacaccagacagggttgaatgctcggctaaagcaggagagcaccagcttcctagg
tctctctggccgttcacccccattgaaaatgggaagcacagtaaatgttctctgtctgat
ctcacaaaagaatccatgccttatgagccgctgtttgacctcgccctgccgaaggtggca
tctctgtttttggagaggaagactgctgaggcctttcggagggttgaaggagaaagagat
caccaagatgagatggaaggagaggatctttctgtcacctcccctctggaggtgttggac
cgggttatccagcagggtcacgacacccatgggaaagtgctgaagagaactttctcttct
ccaagccaatcatcagacccacacttgaaaggtcttgtgcctgcagtgtcggatgagcta
gacatgttacgcagtcaattgctgctgctgcataaccagttgctttatgagagacataag
agagagcaacatgcgcttcgtaaccgtcgtctgtttggccgcatcgtcaacactactgca
ctggaagagcaaaataactccatgaaaacgcagctcaaacttcaggaagttgagatccag
gctgtaaaggtaagcctgaaagaggagcagcggcgctctgtgcacatacaggaagacaga
gaggctgtcgtgaaccagttacagactcaaattcagcagttacagaaggagcggaatgac
tactactcaaagatgcaggtgctaaagagcgagttgcaggagaatcagacaaaggctggc
aaaatggaggcagaactgcagaaagccaataacaaagtgtgtaatatgggtcacatgctc
agccagctatctatcaagctgaacaatagcgaaaacatggagcagcagatggctttcctg
aataagcagctgctgcttttgggtgaagccaacaagttatacatggaagaaattgaccgc
ttgggccctgaggcgcacaaggagctgaatatgctgcaagcatcttcagtgcgggagggt
gagcgtttgaggcagagctctcttcagcagagtcagagacttgaggctgcacagcagcgc
atcacagacctggagaaccaactcaccaagaaagagcaagtcattcgggagcaaaagaaa
ctgctggacaatgtcaaacgacaggccacggagcagctgcaggcttcagaaaacaggtat
ttggctcagaagaacatcactcaggcattacaaactgagctgcttgagctctatagcaag
atagagctcaaaaacctgaaaactaatgcaccagcagagcccatttctgatcccagcagt
cccaccaaccagaggccaaatggcaacagtgcaggcccatctgctccctctctaccggct
gacctgatgaaaagagaggaaggggcgcatgtgtgtgtcaatggtgaaatatctgcagcg
tctcctcaaacacccacagcactcattaatggcagtcaggaagaagatctttccgccctt
actcattcatttccctccctcccctgccaaccctttgcagttggctcttaccccagcacc
agaagctttttgggtaagaaagccagagaaatgttccgcaataagagtgagagccactat
gatggcgactcgcccaccctcacctgcctctcaaaggatcttaaagttgagccaatcaca
gaccccacagagagtttggagtccgaggaagctgctgaccagtttgacctgcagccaatg
gatagaccccgggcatataatgttcagagtaggaggcatcaggatctgcggatcatggac
tataatgagacccaccatgtgcattga

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