Danio rerio (zebrafish): 406702
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Entry
406702 CDS
T01004
Symbol
pdha1a
Name
(RefSeq) pyruvate dehydrogenase E1 subunit alpha 1a
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
dre
Danio rerio (zebrafish)
Pathway
dre00010
Glycolysis / Gluconeogenesis
dre00020
Citrate cycle (TCA cycle)
dre00620
Pyruvate metabolism
dre00785
Lipoic acid metabolism
dre01100
Metabolic pathways
dre01200
Carbon metabolism
dre01210
2-Oxocarboxylic acid metabolism
Module
dre_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
406702 (pdha1a)
00020 Citrate cycle (TCA cycle)
406702 (pdha1a)
00620 Pyruvate metabolism
406702 (pdha1a)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
406702 (pdha1a)
Enzymes [BR:
dre01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
406702 (pdha1a)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
406702
NCBI-ProteinID:
NP_998558
ZFIN:
ZDB-GENE-040426-2719
Ensembl:
ENSDARG00000012387
UniProt:
Q6P948
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Position
5:complement(24031314..24044724)
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AA seq
393 aa
AA seq
DB search
MRKMLTIISNVLRGGASRNGARIVVSARTYADFTPQATFDIKKCDVHKLEEGPAVQAVLT
REEGLQYYRTMQTMRRMELKADQLYKQKIIRGFCHLYDGQEACAVGIEAGINLSDHLITA
YRAHGYTLTRGGTVREIMAELTGRRGGIAKGKGGSMHMYTKHFYGGNGIVGAQVPLGAGV
ALACKYQGKNELCVCLYGDGAANQGQIFETYNMASLWKLPCIFICENNKYGMGTSVERAA
ASTDYYKRGDFIPGLRVDGMDVLCVREATKFAAEHCRSGKGPILMELQTYRYHGHSMSDP
GVSYRTREEIQEVRSKSDPISLLKDRMLSNNMASVEELKEIDVEVRKEIEDAAQFATTDP
EPPLEDLCNHIFYNDPPLEVRGTNPWSKLKSIS
NT seq
1182 nt
NT seq
+upstream
nt +downstream
nt
atgagaaagatgctaaccataatttctaacgttctgaggggcggcgccagcaggaacggt
gccaggattgtggtatctgccaggacatatgcagactttacccctcaggccacctttgat
attaagaaatgtgacgtgcacaagctggaagagggcccagcagtgcaggcagtgctaacc
agagaagaaggccttcaatactaccgaacaatgcagaccatgaggcgcatggagctcaaa
gctgatcagctgtacaagcagaagatcatcaggggcttctgtcacctttatgatggacag
gaagcgtgtgccgtgggtattgaggcgggtattaatctatcagatcatctcatcacagcc
taccgtgcccacgggtacacactcaccagaggaggcaccgttcgggagatcatggctgag
ctgactggtcgtagaggaggtattgccaaaggaaagggagggtcaatgcacatgtacact
aaacatttctatggaggaaatggaattgtgggagctcaggtgcctcttggggcgggtgta
gcgttggcctgcaaataccagggcaagaatgagctgtgtgtttgtctctatggtgatggt
gctgctaatcagggtcagatctttgaaacgtataatatggcatctctgtggaagctgccg
tgcatcttcatttgtgagaacaacaaatacggcatgggtacttctgtggagagagcggcc
gctagtactgactactacaaaagaggcgattttatccctggattgagggtggatggcatg
gatgttctttgtgtgagggaggccaccaaatttgctgctgaacactgcagatcaggaaag
ggtcctattctgatggaactgcagacctatcgttatcatggacacagtatgagcgaccca
ggagtcagctaccgcacacgtgaggagatccaggaggtgcgcagcaagagcgaccctatc
tcgttgctgaaggatcgcatgctgagcaacaacatggccagtgtggaggaactgaaggag
attgatgtggaggtaaggaaagagattgaagacgcagctcagtttgccaccacagaccct
gagcctccgctggaggatctttgcaaccacattttctacaatgaccctcctttggaagtg
cgtggcaccaacccctggtccaaactcaagtccatcagctaa
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