Danio rerio (zebrafish): 406746
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Entry
406746 CDS
T01004
Symbol
fpgs
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
dre
Danio rerio (zebrafish)
Pathway
dre00790
Folate biosynthesis
dre01100
Metabolic pathways
dre01240
Biosynthesis of cofactors
dre04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
406746 (fpgs)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
406746 (fpgs)
Enzymes [BR:
dre01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
406746 (fpgs)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
406746
NCBI-ProteinID:
NP_998602
ZFIN:
ZDB-GENE-040426-2781
Ensembl:
ENSDARG00000044809
UniProt:
F1Q7N0
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Position
21:6114290..6134490
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AA seq
572 aa
AA seq
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MLLFRVLENLRAWTEVSARNRHWTSIVGLSVRFSSTKAAPRYRRMDYQDAVCTLNTLQTN
ASALEQVKRERGHPQLQLQAMRGFLQRAGLKVEELDRLNIIHVTGTKGKGSTCAFTEKIL
RNYGFRTGFYSSPHLVQVRERIRINGQPIGKELFTKYFWQVYGRLEETKDAHGGSMPAYF
RFLTILAFHVFLQEKVDLAVIEVGIGGAYDCTNIIRRPWVCGISSLGIDHTSILGDTIEK
IAWQKGGIFKPGVPAFTVKQPDGPMKVLQERAEEVGCSLSVCPDLDEYESEGSLSLGLAG
QHQRSNASLALQLSHTWLQRHILTDPASPVEFSGVSSAPAFQPSPAMIKGLAETEWPGRN
QTLKHGPVTYYMDGAHTTRSMQACVRWFNEVATQHERNAGGSVLRVLLFNATGERDCAAM
LKLLAPCHFDFAVFCPNITEAIASCNADQQNFNVSVENMLTRCLDNQQSWRVLNGHEEKP
EAELLIGGGLPLVAERHGDTLVFPCILSALQWISQGRDSVLADANKHTIPVKPSINAKAA
PLREAQNIHVLITGSLHLVGGALKHLDPALNS
NT seq
1719 nt
NT seq
+upstream
nt +downstream
nt
atgctgctgttccgcgtgctggagaatttacgcgcgtggactgaagtctcggcgcgtaac
cgacactggaccagcattgtcgggctgtcagtgagattttccagcactaaagctgctccg
cggtaccgaagaatggactatcaggatgcggtttgcaccctcaacaccctccagacgaat
gccagcgctctggagcaggtgaagcgagagcggggacatcctcagctccagctgcaggcc
atgaggggctttcttcagcgagcaggactcaaggtagaagaactggatcgtcttaatatt
attcatgtaactggaacaaaaggaaagggatcaacatgtgccttcacagaaaagattttg
agaaactatggcttccgcactggattctacagttctcctcatttggtgcaagtgagagag
cggatccgaatcaacggtcagccaataggaaaagagcttttcaccaaatacttctggcaa
gtgtatggacgactggaggagacaaaggatgcccatggtggcagcatgcctgcttatttc
cgctttctcactatcttggccttccacgtctttcttcaggagaaggttgatttggccgtt
attgaggtcgggattggtggagcgtacgactgcaccaacattatcaggcgtccttgggtg
tgcggtatctcgtctttaggtatcgatcacactagcattctgggagacaccattgagaaa
atcgcctggcagaaaggagggatttttaagcctggagttcctgcgttcacagtcaaacag
cctgacgggccgatgaaagtgcttcaggagagagcagaagaagttgggtgctcgctgtcg
gtgtgtccagatctggatgagtacgagagcgagggttccctcagcttggggttagctggt
cagcatcagcgcagcaacgcgtctttggctcttcagctctcacacacatggctgcagaga
cacatcctcacagatccagcgtctccagtggagttcagcggtgtgagttcagctccagcg
tttcagcccagtcctgcaatgatcaaaggtcttgcggagactgagtggcctggacgcaat
cagacactaaaacacggtcctgtgacctattacatggatggagctcataccacacgcagc
atgcaggcctgtgtgcgctggttcaatgaggtcgcaacacaacacgagaggaacgcagga
ggttcagtgctgagggttctcttattcaacgctacaggagagagagactgtgccgccatg
ctcaaactgctggcaccctgtcattttgactttgctgtgttttgtccaaacatcacagag
gccatcgcgtcctgtaatgcagaccaacagaacttcaacgtttctgtggagaacatgctg
acccgttgcctggataaccagcagagttggcgcgtcctaaatggacatgaggagaagccg
gaggcagagcttctgattggcggaggcctgccattggttgctgagcgtcacggggacacc
ctggtattcccctgcatcctcagcgccctgcagtggatcagtcagggtcgagactcagtc
ctggcagacgcaaacaaacacacaatacctgtcaagcctagcataaacgctaaagctgcg
ccgcttcgagaggcccagaacatacacgtcctcatcacaggcagcttacacttggtggga
ggagccttaaaacacttggatcccgctttaaactcttaa
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