Danio rerio (zebrafish): 449537
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Entry
449537 CDS
T01004
Symbol
hsd17b2
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
dre
Danio rerio (zebrafish)
Pathway
dre00140
Steroid hormone biosynthesis
dre01100
Metabolic pathways
Module
dre_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
449537 (hsd17b2)
Enzymes [BR:
dre01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
449537 (hsd17b2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
449537 (hsd17b2)
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Motif
Pfam:
adh_short
adh_short_C2
DUF1776
Motif
Other DBs
NCBI-GeneID:
449537
NCBI-ProteinID:
NP_001035278
ZFIN:
ZDB-GENE-040928-1
Ensembl:
ENSDARG00000045553
UniProt:
Q1PLL0
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All DBs
Position
25:38526711..38539779
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AA seq
358 aa
AA seq
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MYTSGIVLYVSFIRSNKRPIAFTSKWRSRGAVAVELSIERRPLVILSSLTTLYFRKIFTL
AGVFSCDSGFGHELAQVLDRAGMRVFAGVLDELSPGALKLKESASVNLTVLQLDITNNTQ
ITQTHQFIKSQTGKTGLWALVNNAGVLGYVCDGEILPMKMYKSCLDVNFLGSVMMTHTFL
PLIRQSRGRVINITSMAGEVPLVGFAGYGASKAALNIYSGAIRQELSRWGVRVIIVQPGA
FRTNILGSSEQWERAQEQILSGLSEEVKDSYGEEYIHSMQKRLLDMSSASSEDKGPFLQS
LKHAILSSNPKHFYYPGAGAWVLSLLYRYCPTALSDKIFSGMFMSGVQPAELARAIPH
NT seq
1077 nt
NT seq
+upstream
nt +downstream
nt
atgtacacctctggcattgttttgtatgtgtcgttcataagatccaataaacggccgatc
gctttcacttcaaaatggcggagtcgcggggctgttgctgtggaactttctattgagcgt
cgccccttggtgattttaagctctttgaccacactgtactttcggaaaatcttcaccctg
gccggagttttcagttgtgactcagggtttggtcatgaactggcccaggttttggaccgt
gcggggatgcgtgtgtttgcaggagttctggatgaactcagtcctggagctctgaaactg
aaggagtctgcatctgtaaacctcaccgtcctgcagttagacatcaccaacaacacacag
atcacacaaacgcatcagttcatcaagagccaaactgacaaaacaggactctgggctctg
gtgaacaatgcgggagtgctgggatacgtgtgcgatggggaaattctgcctatgaaaatg
tataaatcgtgcttggatgtgaatttcctcggcagtgtcatgatgacacacacatttctg
cctctgatacgacaatccagaggaagagtcatcaacatcaccagtatggcaggagaggtc
cctcttgtggggtttgcaggttatggcgcatcaaaagcagcgttgaatatttacagcgga
gcgatcagacaagagctgtccagctggggtgtcagagtcatcatcgttcagcccggagct
ttcagaaccaatatcctgggcagcagcgagcagtgggagcgcgctcaggagcagatcctc
agtggtttatcagaagaggtgaaggactcgtatggtgaagaatacattcactccatgcag
aagcggctgctggatatgtctttagcatcaagtgaagacaaggggccgtttctgcagtct
ttaaagcacgcgatactgtcctccaacccgaaacacttctactaccccggggccggagcg
tgggtgctgtctttactgtacagatactgtccgacggcactgtccgataaaatcttctcc
gggatgtttatgagcggcgtccagcctgcaaaactcgccacagcgattccacattaa
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