Danio rerio (zebrafish): 554124
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Entry
554124 CDS
T01004
Symbol
bckdha
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
dre
Danio rerio (zebrafish)
Pathway
dre00280
Valine, leucine and isoleucine degradation
dre00640
Propanoate metabolism
dre00785
Lipoic acid metabolism
dre01100
Metabolic pathways
dre01210
2-Oxocarboxylic acid metabolism
Module
dre_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
554124 (bckdha)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
554124 (bckdha)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
554124 (bckdha)
Enzymes [BR:
dre01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
554124 (bckdha)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
554124
NCBI-ProteinID:
NP_001019590
ZFIN:
ZDB-GENE-050522-376
Ensembl:
ENSDARG00000040555
UniProt:
Q4VBU0
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All DBs
Position
18:38986941..39001898
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AA seq
446 aa
AA seq
DB search
MAAARAVKKLYGIGLHAIRQNTALKATTLLQQRGFRVNGVLRQQSIDDSDEKPQFPGASA
EFIDHLEFIQPNVISGIPVYRVMDRQGQIINPSEDPQLSKETVLNFYQKMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHIGSAAALDPSDLVFGQYREAGVLMYRGFPLDLFMAQCY
ANADDLGKGRQMPVHYGSKDLNFVTISSPLATQIPQAAGAAYAVKRENANRVVICYFGEG
AASEGDAHAGFNFSATLECPLIFFCRNNGYAISTPTNEQYRGDGIAARGPGYGLMSIRVD
GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRHYMTARDWWGEDEERAWRKQSRKLVMEAFERAERRLKPNPDLMFTDVYDEMVPH
IAKQKDSMWRHVQQYKEHYPLDHYEK
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atggcggctgctagagctgtgaagaaattatatggcattgggcttcatgcaattcgtcaa
aacacagcattaaaagcaacaacgcttctccaacaaaggggattccgcgtcaatggagtt
cttcgtcagcagtcgattgatgattccgacgagaagccgcagtttcctggtgcctcggcg
gagtttattgatcacctggagtttattcagcccaatgtgatctcaggaatccctgtctac
agagtgatggacagacagggccagatcatcaatccctccgaagatccgcagctctcgaaa
gagaccgttttgaatttctatcagaagatgacgttactaaacacaatggaccgtattctt
tatgagtctcagaggcagggccgaatttcattctacatgaccaattacggtgaggagggc
acacatattggaagcgctgcagctcttgacccttctgatctggtctttggccaataccgg
gaagctggtgtgttgatgtacagaggtttccctctggatctgtttatggcacagtgctat
gccaacgctgatgaccttggtaagggcagacaaatgccagttcattacggctccaaagac
ctcaattttgtcaccatctcttcaccacttgccactcagatcccccaagcggctggagca
gcgtacgcagtgaagagggagaacgcaaaccgcgtggtgatctgttactttggagaagga
gctgccagtgaaggagatgctcatgctggatttaacttctccgcaacacttgagtgtcct
ctcatattcttctgccgcaacaacggttatgccatctctacacccaccaatgaacagtac
agaggagatggtattgctgctcgaggtccaggatatggcctgatgtcgatccgtgtagat
ggcaatgatgtatttgcagtgtataatgccacgaaagaggcccgccgcagagctgtggct
gaaaaccagcccttcctcattgaagcgatgacctacaggatcggtcatcacagcaccagt
gacgacagctctgcctaccgttcagtggacgaggtgaactactgggacaagcaggaccac
cccatctctcgcctgcgccactacatgacagcccgcgattggtggggagaggatgaggag
cgcgcctggaggaagcagtcacgaaaactcgtcatggaggccttcgaaagagccgagaga
cgcctgaaacccaaccctgacctgatgttcaccgacgtctacgatgagatggtgcctcac
atcgccaagcagaaagattccatgtggagacacgtccagcaatataaagagcattaccca
cttgaccactatgagaaataa
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