Danio rerio (zebrafish): 559080
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Entry
559080 CDS
T01004
Symbol
cftr
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
dre
Danio rerio (zebrafish)
Pathway
dre02010
ABC transporters
dre04530
Tight junction
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
559080 (cftr)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
559080 (cftr)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
dre02000
]
559080 (cftr)
Enzymes [BR:
dre01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
559080 (cftr)
Transporters [BR:
dre02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
559080 (cftr)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ABC_membrane
CFTR_R
ABC_tran
SMC_N
AAA_21
AAA_29
AAA_16
RsgA_GTPase
nSTAND1
MMR_HSR1
DUF87
FtsK_SpoIIIE
AAA_23
Dynamin_N
MeaB
T2SSE
DUF5805
Motif
Other DBs
NCBI-GeneID:
559080
NCBI-ProteinID:
NP_001038348
ZFIN:
ZDB-GENE-050517-20
Ensembl:
ENSDARG00000041107
UniProt:
Q1LX78
Structure
PDB
PDBj
LinkDB
All DBs
Position
18:20677184..20722548
Genome browser
AA seq
1485 aa
AA seq
DB search
MQRSPVEDANCLSRYFFWWTNPIMRKGFKEKLRPSDVYQAPSQDAADILAERLEKEWDRE
VASGKKKPSLLRAMARCYIKPFLLFGFLLYIGEATKTVQPQLLGRIIASFDPAHEPERAN
GYFLAFGLGLLFTARFLLLQPAMFGLHHLGMQIRIALFSIIYKKTLKLSSRVLDKISTGQ
LVSLMSANLGKFDQSLGMAHFIWISPLQCILCTGLIWELIDVNSFCALAAISLLGVLQAF
LSHKMGPYKAQKVLLTNKRLALTSEIMENLHSVKAYGWEEIMETLIKNIRQDEVKLTRKI
GSLRYFYSSAYFFSAIFVIVAAVVPHALSRGINLRRIFTTLSYCMVLRMTVTRQLPGSIQ
MWYDTMRLIWKIEEFLSKEEYKLMEYDLSITELELQDVTASWDEGPGELLERIKQENKAN
GHHNGDAGLFFTNLYVAPVLKDISLKLKKGEMLAVTGSMGSGKSSLLMTILGELVPSSGK
IRHSGRISYSSQTAWIMPGTIRDNILFGLTYDEYRYKSVVKACQLEEDLAALPEKDKTPM
AEGGLNLSGGQKARVALARAVYRDADLYLLDAPFTHLDIATEKEIFDKCLCKLMASKTRI
LVTNKIEHLKRADKILLLHNGESFFYGTFPELQSERPDFSSLLLGLEAYDNISAERRCSI
LTETLHRVSVDESAGMQPERSAFRQVPPTKPMYIDERKASVIVNPLGVARKASFIQVPEE
EVRRTLPDRKFSLVPENELVDESFMGSDVYHNHGVHMAGQRRQSVLAFMTNAQGQGRREH
LQSSFRRRLSVVPQSELASELDIYTRRLSDSTYDMTGILEEENIEACLTDEIDEIEETFE
TTKWNTYVRYVSNNKSLLYVLIFILFIAAIEIAGSVAGIFLITDELWREEHQRSEPNMTK
HSNASSSGQTYAITVTPTSSYYILYIYVATSESLLAMGFFRGLPFVHTTITISKKLHQKM
LHAVLSAPMSVLNTMKTGRIMNRFTKDMATIDDMLPLLMFDFVQLTVVVVGCILVVSIVR
PYIFLAATPLAIIFIVMRKYFLRTGQQLKQLETEARSPIFSHLIMSLKGLWTIRAFERQA
YFEALFHKTLNTHTATWFLYLSTLRWFLFRADILFVFFFTLAAWIAVGTNQDKPGEIGII
ICLAMLILGTFQWCVATSIAVDGMMRSVDRVFKFIDLPSETPKPDKGKDSDLIIENVDAQ
ADSSWPHRGQIEVRNLTVKYTEAGHAVLKNLSFSAEGRQRVGILGRTGSGKSSLFNALLK
LVYTDGEISIDGVNWNKMPLQKWRKAFGVVPQKVFIFTGPLRMNLDPYGCHSDEELWRVA
EEVGLKTVIEQFPDKLDFQLEYGGYVLSNGHKQLICLARSILSGARILLLDEPSAHLDPV
TIKVLKKTLRQSFSTCTILLSEHKVEPLLECQSFLMMDKGQVKTYDSIQKLLNETSHLKQ
AISPAERLKLFPRRNSSMRTPQSKLSSVTQTLQEEAEDNIQDTRL
NT seq
4458 nt
NT seq
+upstream
nt +downstream
nt
atgcagagatcacctgtggaggatgccaactgcctctccagatacttcttttggtggaca
aaccctattatgagaaagggttttaaggagaaactgaggccatccgatgtttatcaagca
cccagtcaagatgcagcagacatcctcgcagagcgcttggaaaaggaatgggacagagaa
gttgcatctggaaagaaaaaacccagtctcctgagagcgatggcacgatgctacataaaa
ccttttctgttgtttggcttcctgctgtatattggtgaagctacaaaaacagtgcaaccg
cagcttttaggacggatcattgcatcatttgacccggcccatgagccggagcgagccaat
ggatactttcttgcctttggtcttggtttgttgtttactgcccgcttcctcctgctccag
cctgccatgtttgggctgcaccacctgggcatgcaaatcaggattgcactctttagcata
atatataaaaagaccttgaaactttccagccgtgtcttggacaagatcagcacaggtcag
ctggtcagtctgatgtcggccaacctgggcaagtttgatcagagcctgggtatggcccat
tttatatggatatcaccactgcaatgcatcctgtgtacagggcttatctgggaactcatt
gatgtcaatagcttctgtgcacttgccgccatctctttactgggtgttttgcaggccttc
ctttcacataaaatgggtccttacaaagcacagaaggtgctgttgaccaacaaacggctg
gctctgacctcagagatcatggagaacctgcattcggtaaaggcgtatggctgggaggag
ataatggagacactcatcaagaacatcagacaggatgaggtgaagctgaccaggaagatc
ggctcgctgcgctacttctacagctcggcgtactttttctcggccatctttgtgattgtg
gctgcagtggtgcctcatgctctgagtcggggaatcaacctgcgccgcattttcaccact
ctctcctactgtatggtgctgcggatgacagtcacccgacagctgcccggctccatccag
atgtggtacgacaccatgcggctcatctggaagattgaagaatttcttagtaaagaagaa
tacaagttaatggagtacgatctcagcatcacagagctggagcttcaagatgtgactgct
tcatgggatgagggtcccggtgaacttttggaaaggataaaacaggagaacaaagctaat
gggcatcacaatggagacgcaggcctcttcttcactaacctgtatgtggctcctgtactg
aaggacatcagtctgaagctgaagaaaggagagatgttggctgttactggttctatggga
tctgggaaaagctcattgttgatgaccatcctcggggagctggttccctcctcagggaag
atccgacacagcggtcgaatctcttactcctcccaaacagcctggatcatgcctggaacc
atccgagacaacatcctctttggcctgacctacgacgagtatcgctacaagagtgtggtg
aaagcgtgccagcttgaggaggatctggctgctcttccagagaaggataagacacctatg
gctgagggcggtttaaacttgagcgggggtcagaaggcacgcgtggctctggccagggct
gtttacagagatgctgatctttacctacttgacgcaccattcactcatctggatattgca
acagaaaaggaaatatttgacaaatgcctctgtaaactgatggcctcaaagacacgcatc
ttggtcacaaataagattgaacatttgaagcgggctgataagatcctactgctccacaac
ggtgaaagctttttctacggcacctttcctgagcttcagtcagagcggccggatttcagc
tctttgcttctaggtttggaggcctacgacaatatcagtgccgaacgtcgctgctccatc
cttaccgagaccctccatcgcgtctcagtagatgaaagcgccggcatgcaacctgaacgc
tcggcttttcgtcaggtgcctccaaccaagcccatgtacatcgacgaaagaaaagcttca
gtaatcgtcaaccctcttggggtggctcgtaaggcatcttttattcaggtcccagaggaa
gaggtgcggaggacattacctgacagaaagttctccctggtgcctgagaacgagttagtg
gatgagtccttcatggggagcgatgtgtatcataaccatggagtgcatatggctggtcag
aggaggcagtcggtgttagcctttatgaccaatgcacagggccagggtcgtcgcgagcac
ctccagtcatctttccgcagacgtctttctgtcgtgcctcagagtgaactggcatctgag
ctggacatctacactcgccgactatcggacagcacgtatgacatgactggcatcctggag
gaagaaaacattgaggcatgcttaactgatgaaattgatgaaatagaagaaacattcgag
acgacaaagtggaacacatacgtcagatatgtgtcaaataataaaagccttctttatgtt
ctgatcttcatcctctttattgctgcaattgagattgcaggatctgtagcagggattttt
ctgataaccgatgaactttggagagaggaacatcaacgatctgagccaaacatgacaaag
cactccaacgcgtcttcatctggacaaacatatgccatcactgtgactcccacaagcagc
tattacattctctacatatatgtggccacgtcagagagcctcctcgcgatgggatttttc
agaggtcttccgtttgtacacacaaccatcaccatctccaaaaaactgcaccagaagatg
ctacatgctgttctcagtgctcccatgtctgtactcaacactatgaagacaggccgaatc
atgaatagattcaccaaagatatggccacaatagacgacatgcttcctctcctcatgttt
gactttgtccagctgacagtagtggtggttggatgtattcttgtggtgtccattgtgcgg
ccgtatatattcctcgctgctactcccctggccattattttcattgtgatgaggaagtac
tttctccgcacgggtcaacagcttaaacagctggagacagaagcccggagccccattttc
tcgcacctcatcatgtctctgaagggtttgtggaccatcagggctttcgagcgacaggcc
tacttcgaggcccttttccacaagacactcaacacccacacggccacctggttcctctac
ttgtccactctccgatggttcctcttccgcgccgacatcctcttcgtcttctttttcacg
ctggccgcctggatagcggtaggaaccaaccaggataaaccgggcgagattggtatcatc
atatgcctggcaatgctcattctcggcacctttcagtggtgtgttgccaccagcattgca
gtggatggaatgatgcgttcggttgaccgggtgtttaagttcattgaccttccatctgag
acgcccaaaccagacaaaggcaaagactcagatctgattattgagaacgtcgatgcacag
gctgactcgagctggccacaccgcggtcagatcgaagtgaggaatttaacagtcaaatac
acagaagcgggtcacgctgtcctcaaaaacctgtccttcagtgcggaggggagacagagg
gtgggcatcttgggccgaacaggttcagggaagagttctctgttcaatgccctcctgaag
ctggtttatactgatggcgaaatctccatcgacggggtcaactggaacaaaatgccgctt
cagaaatggaggaaagcctttggtgtagtgcctcagaaagtgttcatctttacgggaccg
ttacgcatgaacctggacccttatggctgtcacagtgatgaagagctgtggcgggtcgct
gaggaggtgggtctgaagacagtgattgagcagtttccagacaaactggacttccagctg
gagtacggcggttatgtgctgagtaacggccacaaacagctcatatgcctggctcgctct
atcctcagcggagcccggatcctcctcctggatgagcccagcgctcacctcgaccctgta
acaataaaggtgctgaagaagacactgagacagtctttctccacatgcactatattactg
tctgaacacaaagtggagccgctgctcgagtgccagtctttcctgatgatggacaagggt
caggtgaagacctacgactccatccaaaagcttctgaatgagaccagtcacctaaagcag
gccatcagtccagccgagcggcttaaactcttccctcgccgaaactccagcatgaggacg
cctcaatccaaactgagctcagtcacgcagaccctgcaagaggaggcagaggacaacatc
caggacactcgcctctga
DBGET
integrated database retrieval system
