KEGG   Danio rerio (zebrafish): 561159
Entry
561159            CDS       T01004                                 
Symbol
wnk1b
Name
(RefSeq) serine/threonine-protein kinase WNK1 isoform X1
  KO
K08867  WNK lysine deficient protein kinase [EC:2.7.11.1]
Organism
dre  Danio rerio (zebrafish)
Brite
KEGG Orthology (KO) [BR:dre00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dre01001]
    561159 (wnk1b)
   01009 Protein phosphatases and associated proteins [BR:dre01009]
    561159 (wnk1b)
Enzymes [BR:dre01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     561159 (wnk1b)
Protein kinases [BR:dre01001]
 Serine/threonine kinases: Other
  Wnk family
   561159 (wnk1b)
Protein phosphatases and associated proteins [BR:dre01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     561159 (wnk1b)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr OSR1_C CCTL2_WNK
Other DBs
NCBI-GeneID: 561159
NCBI-ProteinID: XP_021327176
ZFIN: ZDB-GENE-030131-2656
Ensembl: ENSDARG00000039392
UniProt: A0A8M9PXY8
LinkDB
Position
4:complement(8534625..8642434)
AA seq 2463 aa
MSSENPNKVVTFLAPPPPKNVNGSGSDSLVGEKLDTEVRKRRHTMDKDLKTAEHRFFRRS
VICDSNATALDLPSKACILTSPPDCEQFVIPTVLSSTPDVTLDTQTVVSAAVVEERSEDE
RRAGVEGIVEVQSPSVQDAGSRQSEVLGKVETELSDVGDKEQESRVTDKQEEEERGVAKA
RAEAELREAVKKEQDEIEEVETKAVGTSPDGRFLKFDIEIGRGSFKTVYKGLDTETTVEV
AWCELQDRKLSRSERQRFKEEAGMLKGLQHPNIVRFYDSWESPSKGRKCIVLVTELMTSG
TLKTYLKRFKVMKIKVLRSWCRQILKGLHFLHTRAPPIIHRDLKCDNIFITGPTGSVKIG
DLGLATLKRSSFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQN
PAQIYRRVTSGVKPGSFDKVAIPEVKEIIEGCIRQNKDERYAIKDLLNHAFFQEETGVRV
ELAEEDDGEMIAIKLWLRIEDVKKLKGKYKDNEAIEFSFDLHRDVPDDVAQEMVESGYVC
EGDHKTMAKAIRDRVSLISRKREQRQQVRAEQEKRKQEEEQKLLSSESIKNVAGAQGTQG
SLQSQCSSQPPTPGLVQPECEEPDADPQHQYMQSGITLADGTFDSGQGSSVFSEPHLSQL
SMSYSSPGTSQQQQVPGQGTYTPSSQAPQQHTAYPQQPMPQSVSQPYGGGGSGLVEPPLF
FPTIPERPVSFSPPPSCPPKAFNVQRRKSTSILEAHTRHFQPAYHRSYGSSLHPFSGVEA
LGATVEPSMFMMPGMPAQRLADPLHLQPPTESLYGYKDVRAEQEETVRRLSLNQAALMDH
LEAMAYSGYPMTAHQLSHISFHQQMQAAAASLAYETQSQQPGPAYLHPHLQSHMRLTHSP
IPQLPPMSVPSSASAPQQATVADPSYQSHSFPHSAPPVLAHASEPNTAFEFHMHNLQADP
AMLASRLYRARRGSMDLNLEEAGGNPGLCSRLQPVTEELYSYVSPELPLPPGSLLLHGPK
ELSPEPSSDSMTSSDAGEFHSPPPHQLYQTQECSAAQSIPQAAYYKTDGGSNVSDGHPPS
QPTFLFVPHSESSTISSSHINAWARQPSLPPDLTFHEPALSHQGATLVQVPIPQSTSGMS
LASCSTPAASASQQYGVYYVQALPTQAPVQQPASLGPTSQPCASLPQQQTPQQPSSTVAQ
SISQTQITPTQLCSPALCVPTIAVTPFQQQPVPEALTSLKTAPATSPSMLPPHVPLLVTT
PVPTIHVATVPSPTEHPCLPADALAQTSHSASQTLTTELSQLQTPAVESSHSDVASGLSD
GNEGVTGGRHEGRPAKRHQRRSVRSRSRNEKTSKVKLSVLNISSMGDRVAECQLETHNRK
MVTFKFDLDGDNPEEIAQIMVQSEFILESERESFIDRIREVIETADEKGVERERSQMASD
HEQLMPTTSAPLEHGRTYNLSVPPSSAAQVVHSAGRRFIVSPVPESRLKDQFFSPSQPTI
PLHEEPAPVPVALPALGLSVSASAVSLQQAFTEMRQAHFDPGPSTAPPMLHNSMPPLLPA
TTPLPSSATPVVSPPVSSEVTSSPSLPSINPPVSSSPPPTVPVNSVTSPPAQLTLPQSQV
APAVISVIPTPSTLPMPAVPTATSLPQTSVTVPSSTPIAPMGSVSGGSGEQPSIPATSSP
TSATIQTPQLAPSTIPTTTAQSQVPPLQPVTTTMPVVQPTPVHSQPQTTTVPNQSHAHSV
ECDSDQQGKVDDIQALDKKLRSLFMDLGSGPPSAQSDVTSDPTATPSVPGTSSPTTCATP
SGTPLPPSSLPLNSSTQSAGSPMTSMGNASTPVGYSQTTPSKAPLTRLPVLPVGPDQAGT
PPTEHLPPFPGPGLIQSQQPLEDLDAQLRRALSPETVPISSVTHQSSLTGMPPGGQPVPF
SLDDEQAAAPAAGGYKLGRFQVSVATDENTTQTPTSSSSSTSSSSTTSSSSSSCSLSSPE
NTLHRTSSPLIDTGADVVDGLPALPNQTTTQPQPTTIGRFQVTTKTDTQVGRFSVSKAQD
EVTTSTSQPQPTPQTHSAVGNGPAQSPGSLNNSISSYFSSDNDSEFEDEDFKREVSRLRD
KHMIESQALYSRQKAEIEALFARLGKVPPAMVNPPVVNPAGRRRRPTKSKSSKSSRGSSQ
ASKSPVQPATSTLSAQSAPSVYPAQQAFLAPGGMMDGGSSPLLQSFKPSPSNDNLCSTFT
SDATLSAPSLCVTSQGCVKFSCGSERVTFKPGGRRTRFLSTPCLALWKMVKKVCPCNQLC
RTSSTNTVAGPGQNQSQPPVSQSQSCKGMFTDELHKLVDNWARDAMNLSQGKRGSKHQQQ
VVPQGHSYEMVPPVNMGRKYSAPGQLCPSIASTLSGHPPMPNTPATSLGARKGSLCPTPQ
YGYPSAPYSAQWAGAATHTQAGLLATSQPLGQYPQVPTPLQTFHISTLQKSVSHPGGPNL
KST
NT seq 7392 nt   +upstreamnt  +downstreamnt
atgtcatcggaaaatcccaacaaggtggtgaccttcttggccccgccacctccaaagaat
gtgaatggctccggttcagactcgctggttggtgagaagctagacacggaggtcagaaag
cgacgccacaccatggataaagatctgaagacggccgagcatagatttttcagacgtagc
gtcatctgtgactccaatgccacagcccttgacttgcccagcaaggcctgcatcctcacc
tcacctccagactgcgagcagtttgttatacccacggtgctgagttcgacccctgatgta
actcttgacacccaaacagtagtttcggcggccgtagtggaagaacgttcagaggatgaa
agacgtgctggggttgaagggattgtggaggtacagagtccttctgtgcaggatgcaggc
tcaaggcagagtgaagtccttgggaaggtggagaccgagctcagtgatgttggtgacaaa
gagcaagagagtcgagtgacagacaagcaggaggaggaggagagaggggtggcgaaggcc
cgtgctgaagctgagctgagggaggctgtgaaaaaggagcaggacgaaattgaagaagtc
gagaccaaagctgtgggcacctctcctgatggccgcttcctcaaatttgacatcgaaatt
ggacgtggatcattcaaaacggtctacaagggcttggacacagagacaacagtggaggtg
gcgtggtgtgaacttcaggatcggaagctgtccagatcagagcgccagagattcaaggaa
gaggccggcatgctgaaaggcctgcagcacccaaacattgtgcgtttttacgattcatgg
gagtctccttccaaagggaggaagtgcatagtgctggtgacggagctcatgacatcagga
accctgaaaacatatctgaaacgcttcaaggtgatgaagataaaggtgttgcgaagctgg
tgccgacaaatcctgaagggcctgcacttcctgcacaccagggctccaccaatcatccac
cgggacctgaagtgtgacaacatcttcatcaccggacccaccggctcagtaaagatcggt
gatctgggcctggccaccctcaagcgttcttcgttcgctaaaagcgtcataggtacccct
gagttcatggcgcctgagatgtacgaggaaaaatacgacgagtcggtggacgtgtacgcc
ttcgggatgtgcatgctggagatggctacctcagagtacccgtactccgagtgtcaaaac
cctgctcaaatctatcgcagagtcaccagcggagttaaacctggcagtttcgacaaggta
gccattccagaagtgaaagagatcatcgagggatgtattcggcaaaacaaagatgaaaga
tacgccattaaagaccttctgaaccatgccttcttccaagaggagaccggggtgcgggtg
gaactggctgaggaggatgatggggagatgatcgccatcaagctctggttgcgcattgaa
gacgtcaagaaactgaaaggcaaatacaaagacaacgaagccatcgagttctccttcgac
ctccatcgggacgtgccagacgatgtggctcaggaaatggtcgagtcgggttatgtttgc
gagggtgaccacaaaaccatggccaaggccatcagggaccgtgtgtcgctgatctcccgc
aaacgagaacaacgacaacaggtgcgagccgagcaagaaaaacgcaagcaggaggaagag
cagaaactgttatccagtgagtctattaagaacgtggccggagctcaaggaacgcaaggt
tctctacagagtcagtgtagctcccaacctccaactcccggccttgtgcagcccgagtgt
gaggagcctgatgcagatccgcaacatcaatacatgcaaagtggaataaccttggcggac
gggacatttgacagtggtcagggttcatcagtgttctcagaacctcacctcagccagcta
agcatgtcgtatagttctcctggaacatcccaacaacagcaggtcccaggacagggcacc
tacactcccagctctcaagctccccaacagcacaccgcatatccccagcagcccatgccg
caatcagtgagtcagccgtacggcggaggaggctcaggtctggtcgagcccccactcttt
ttccccaccatcccggaacggcccgtctcattctcccctccaccatcttgcccacctaaa
gctttcaacgtgcagcgccgcaagagcacctccatcctggaggcccacacgcgtcacttc
cagcccgcctaccaccggagctatggtagcagcctgcacccattctctggcgtggaggca
cttggtgccacagtcgaaccttctatgtttatgatgcccgggatgccggctcaaagattg
gcggatccacttcacctacagcctccaacagaatcactatatggatataaagatgtaaga
gcagagcaagaagaaacagtacgcaggctcagcctcaaccaggctgcattaatggaccat
cttgaagccatggcctacagcggctaccctatgactgcgcatcagctaagccacatcagc
ttccatcagcaaatgcaagccgctgctgctagcttagcctatgagactcagtctcagcaa
cctgggccagcctacctacaccctcacctacagagccacatgcgcttgacccacagccca
atcccccaactacctccaatgagtgtccctagctctgcttctgcaccgcagcaagccaca
gttgcagatccaagctatcagtcccactcgtttccccattctgcaccacctgtgttggcc
catgcatcagagccgaacacagcctttgaattccacatgcacaatctccaggcagaccca
gccatgttggcatctagactctaccgagcccgtcggggctccatggaccttaacctggag
gaagcaggtggcaacccgggattgtgtagccgactccagccagtcacagaagaactgtat
agttatgtgagcccagagctccctcttccaccaggcagcctgcttcttcatggacctaaa
gagctcagtcctgaaccatcaagtgactccatgacctcctcagatgcgggggagtttcac
tcacctccgccacatcaattgtaccaaactcaagagtgttctgctgctcaatccatccca
caagcagcttactacaaaacagatggagggagtaatgtcagcgatggacacccacccagt
caacctacgtttctgttcgttcctcactctgaatcatccacaatttcgtcttcacacatc
aatgcctgggcccgtcaaccatcccttccaccggacctcacattccacgagcctgccttg
tcccatcagggcgctactttggttcaagtccccattcctcagtctacaagtggcatgtct
ctggcttcctgcagcaccccagccgcctctgcctcccaacagtatggagtttactacgtc
caagcactccctacgcaggctcctgttcagcagccggcctctctaggtcccacttcccaa
ccctgtgcctcgctaccccaacaacaaacaccccaacagccttccagcactgtagctcag
agcatctcccaaacgcaaatcacgccaacacagctttgcagtccggctctctgcgttcca
actatagcagtcaccccgtttcagcagcaacctgtgcctgaagcgctgacgtccctgaaa
actgcgccagccacctccccttcaatgctgccgccccatgtacccctattggtaacaaca
cctgtgccaaccatccatgtggccacagtcccttcccccaccgaacatccgtgtttgcca
gcagacgccttggcgcagacgtctcacagcgcatcgcagactttgacaacagagctgtca
caactccaaactcctgctgtggagagcagtcattctgatgtagcttctgggctcagtgat
ggcaatgagggcgtaacaggtggtagacatgagggtcgtcctgccaaaagacaccagcgc
agatcggtgcgcagccgttcacgcaatgaaaagacctcgaaggtcaagctcagtgtgctt
aatatctccagcatgggtgacagagttgcagagtgtcaattagaaacacacaacaggaaa
atggtgactttcaagttcgatcttgatggtgataacccagaggaaattgcacagataatg
gtacaaagtgaattcattcttgaaagcgagcgtgaatcgttcatcgatcggatccgagaa
gtgatcgaaacagctgatgagaagggggtggagagagagcgcagtcagatggccagtgat
catgagcagcttatgcccacaacatctgcgcctcttgaacatggtagaacttacaatctc
agtgtaccacctagttcagctgcacaggtggttcattctgcaggccgcaggtttatcgtg
agtccagtgcctgaatccagactgaaggatcagttctttagcccatcccaacctacaatc
ccacttcatgaagaacctgcccctgtgccagttgcattgcctgccttggggctctctgtg
tctgcgtctgctgtcagcctgcagcaggcgttcactgagatgcgtcaagcccactttgac
ccaggtcccagcactgcaccccctatgctccacaactccatgccccctctgcttcctgcc
acaacacccttgccctctagtgccaccccagtggtctctcccccagtgtcttcagaagtg
acctcttcgccatctctaccttctataaaccctccagtgtcatcatctcctcctccaacc
gtcccggtcaattccgtaacctcccctccagcacaactcaccctgcctcaaagtcaagtt
gcgcctgccgtcatcagtgttattcccaccccttccactctgccaatgccagcggtgcca
actgccacatcccttccacaaacttcagtcaccgtaccttccagcacaccaatcgctcca
atgggatcagtgtccggaggcagtggagaacaaccatccatccctgctacttcttcgccc
actagcgctacaatccaaacgccacagctggcaccatccaccatccccaccaccacggct
cagtcacaagtgccccctctccagccggtgaccacaaccatgccagtcgtgcagcccaca
ccagtgcacagccaaccacagaccaccaccgtgcccaatcagagccatgcgcatagtgtt
gaatgcgacagtgaccagcagggcaaggttgatgacatccaggctctagataagaagctg
cgctcgctctttatggacttgggctccggtcccccatctgcccagtctgatgtcacatcc
gacccgacggcgactccaagcgttcctggcacctcgtctccaaccacatgtgccaccccc
agcgggactccactccctccctctagtttacccctgaactcctccactcagtctgcgggg
tctcccatgacctccatgggcaatgcctccaccccggtcggctacagtcagaccactcca
tccaaagctcccttaacacgattaccggtgttgcctgtcggcccagatcaggctggcacg
ccgcccacagagcaccttccacccttcccaggacctggtttaattcagtcccagcagccc
ctggaggatctggatgcccagctgagacgggcactgagtccggagaccgtcccaatcagc
agtgtcacgcaccagtcatctctaaccgggatgccacctggaggacagccagttccgttt
tctctggatgatgagcaagcagccgcacctgcagctggaggatacaaactggggcgattc
caggtgtcggtggccactgatgagaacaccacacagactccaaccagctcatcctcttcc
acatcatcttcctccaccacctcctcttcctcctcctcctgtagtctgtccagccctgaa
aacacactgcacagaacctcctctcccctcatagacacaggcgcagatgtggtcgatggt
ctccctgctctccccaaccagacaacgacccagcctcagcccaccaccatcggccgcttc
caggtcacgaccaaaacagacacgcaggtgggacgcttctctgttagcaaagcacaggac
gaggtgactacatccacctcacaacctcagcccacacctcaaacccattctgctgtgggc
aacggtccagcacagagtcccgggagcttaaacaactccatcagctcctatttcagcagc
gataatgactcggagtttgaagacgaggactttaagagagaagtcagcaggctgagagac
aagcacatgatagagagtcaggctctatattctcgtcagaaagcagagattgaggctctg
tttgcccgtttggggaaagttccacctgctatggttaacccacctgtggtgaacccagcc
ggccgcaggagacgccccaccaagagcaaaagcagcaaatccagccgcgggagctcgcag
gctagcaagagtcccgtacagccagcaaccagcactttatcagcacagagcgccccttct
gtgtacccagcccagcaggccttcctggcccccggggggatgatggatggggggagcagc
cctctgctgcagtctttcaaaccctcgccctccaatgacaacctgtgctccactttcacc
agtgacgccacgctctctgcgcccagtctctgtgtaacctcgcaaggctgtgtaaagttc
agctgtggctcggagagagtgaccttcaaaccaggtggcaggaggacgcgttttctgagt
acgccctgcttggctctttggaagatggtgaaaaaagtctgcccctgcaaccaactctgt
aggacgagcagcaccaacacggtggcaggacccggtcagaaccaaagccagccacccgtc
tctcagtctcagagctgcaagggcatgttcacagacgagctgcacaaactggtggacaac
tgggcccgggacgccatgaacctatcacagggcaagagaggctccaaacaccaacagcaa
gtggttcctcagggccacagctacgaaatggttcctccagtaaacatgggccgtaagtac
tcagctccgggtcagctgtgcccaagcatcgcttcaactctgagcggccatccaccaatg
cccaacactcccgctacctctctaggagctcggaagggctccttgtgtcccacgccgcag
tacggctacccctccgcaccttacagcgcccagtgggctggagcggccacgcacacccag
gccggtctgctggccacctcacaacccctgggccaatatccccaggtgcccaccccttta
cagaccttccacatcagcactttgcaaaagtcagtcagccacccgggcggacccaatctg
aagagcacgtag

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