KEGG   Danio rerio (zebrafish): 565669
Entry
565669            CDS       T01004                                 
Symbol
plcd4a
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1
  KO
K05857  phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
Organism
dre  Danio rerio (zebrafish)
Pathway
dre00562  Inositol phosphate metabolism
dre01100  Metabolic pathways
dre04020  Calcium signaling pathway
dre04070  Phosphatidylinositol signaling system
Module
dre_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:dre00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    565669 (plcd4a)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    565669 (plcd4a)
   04070 Phosphatidylinositol signaling system
    565669 (plcd4a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dre04131]
    565669 (plcd4a)
Enzymes [BR:dre01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     565669 (plcd4a)
Membrane trafficking [BR:dre04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    565669 (plcd4a)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    565669 (plcd4a)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y EF-hand_like EF-hand_10 C2 PH EF-hand_1 EF-hand_6 EF-hand_7 PH_12 EF-hand_5 EF-hand_15 S_100 EF-hand_PLCG2 DUF4028
Other DBs
NCBI-GeneID: 565669
NCBI-ProteinID: XP_073793517
ZFIN: ZDB-GENE-050208-654
Ensembl: ENSDARG00000057975
LinkDB
Position
22:complement(12424110..12441680)
AA seq 768 aa
MTERQMASTERSLRKFHLNYGIQADDDLKSMIVGTVMRKIKSRTWKKQRYFRLQEDCMTI
WYQSKKAGNAHSTFSVGDVEAVREGHQSEVLLSIADEFPPDRCFTLVFRGRRGNLDLVAE
STKEAQSWIKGIRKLIDNLENMGQREKLDQWICDWFKKADKNRDGRMNFKEVRDLLKMMN
VDMNEHHALRLFTMADRSQSGTLEDDEFVLFYKMLTQREDILRVFQEYSADGQKLTLKDL
KDFLQEEQLHEDGVQQYALNLIERFEPSDTAKMLQAMTFDGFLMYLSSSEGSIFNPAMLE
LYQDMSQPLCHYFISSSHNTYLLEDQIRGLSSVEGYIRALKRGCRCVEVDCWDGPNGEPI
VYHGHTFTSKIFFKDVVTVLGNYSFKASEYPVILSIENHCSVEQQKIMAQHLTQILGDKL
LKSTLDGKIPLGLPSPEDLKGKILLKGKKIGGLEDGMNGVVDDPLMGEVSDEEEATEIED
ENHRNNSIRHRSKKSKQRLSKELSDCVVYCKSVHFSSFKHSRNHSKFYEISSFTESKARK
HIREAGAEFVLHNARQLSRVYPSGLRTDSSNFNPQDLWNAGCQIVALNFQTAGVEMDLND
GLFNQNGRCGYVLKPAFMRNFEEMFDPENPQNREDYKPLSLSIQVISGQQLPKVNIKEGS
IIDPFVRVEIHGVPLDQAKQETRYIDNNGFNPVWYDTLQFTIHAPELALVRFVVEDYDKT
SKNDFVGQFTLPFTCIQPGYRHIHLLSKDGTSIPPSSLFVHIRITNLT
NT seq 2307 nt   +upstreamnt  +downstreamnt
atgacagaacgacagatggcttctactgaaaggagcctacgtaagtttcatttaaactat
ggtatccaggctgatgatgacctgaagtccatgattgttggcacagtgatgagaaaaatc
aagtctcgcacatggaaaaagcagcgttacttcaggctacaagaagactgcatgactatc
tggtaccagagcaagaaagcaggaaatgcccactccaccttttctgtgggtgatgttgag
gctgtacgggaagggcaccaatcagaggttctactcagcattgccgacgagtttcctcct
gaccggtgcttcacccttgtgtttcgtggacgaagaggcaacttggacctagtggccgaa
tccacaaaggaggcacaatcatggataaaagggatacgcaaactcatcgataacctagag
aacatggggcagagagagaaactggaccaatggatctgtgactggtttaaaaaggcagac
aaaaaccgagacggacggatgaactttaaggaggtcagagatctgttgaagatgatgaac
gtggacatgaacgagcaccacgctctccgtctcttcacgatggcggatcggtctcagtcg
ggaacactcgaggatgatgagtttgtgttgttttataagatgctgactcagcgcgaggac
atcctgcgagtgtttcaggaatattcagccgatggacagaagctaacgctcaaagatctg
aaagatttcttgcaggaggaacagttacatgaggacggagttcaacaatacgcacttaat
ctcattgaacgctttgaaccatctgacacggcgaaaatgttacaagcaatgacgtttgat
ggtttcctaatgtacctgagctcatcagagggctccatcttcaaccctgcaatgctcgaa
ctctaccaagacatgtctcagcctctctgccattatttcatatcatcttctcataacaca
tacctactggaggaccaaatcagaggacttagcagtgtggaaggctatatacgagcactg
aaacgtggctgtcgatgtgtggaagtggactgttgggatggaccaaatggagagccaatt
gtctatcatgggcacacattcacatccaagatcttcttcaaggatgttgtcactgtgctg
ggcaactattcttttaaagcatcagagtaccctgtcatcctgtccattgagaaccactgc
agtgtagagcagcagaaaatcatggcccaacacctcacccagatcctgggagacaagctg
ctgaaaagcactttagatggaaagattcccctcggcctcccgtcccctgaggatctgaaa
gggaagattctgttgaaaggaaagaagataggtggattagaggatggcatgaatggagta
gtggatgaccctttgatgggagaggtgagcgacgaagaggaggccactgaaattgaggat
gaaaatcatcgcaacaacagcatacgacacagaagcaagaaatccaaacagcggctgtct
aaagagctgtccgactgtgtggtttactgcaagagtgtccactttagcagctttaaacat
tcacgaaatcactccaagttttacgagatctcctccttcacggagtctaaggcccggaag
cacataagggaggcaggagcagagtttgttcttcataatgcccgtcagttgagtcgggtt
taccctagtggtttgagaaccgactcctccaactttaacccacaggacttgtggaatgca
gggtgccaaattgttgctctaaactttcagacagcaggggttgagatggacctaaatgac
ggcttattcaatcaaaatggacgttgtggctacgtattaaaaccagcgttcatgcgcaac
tttgaagagatgtttgaccccgaaaaccctcaaaatcgagaagattacaagccacttagc
ctgtccatacaggtgatcagcggccaacagcttccaaaagtaaacatcaaggagggctca
atcattgaccccttcgttcgagtggagattcatggcgtaccactggatcaggccaagcag
gaaaccagatacattgacaacaacggttttaacccggtatggtacgacacccttcaattc
accattcacgctcctgaattggcactggtgcggtttgtcgtagaagactatgataaaacc
tcaaagaacgactttgtgggacagttcactctccctttcacctgtattcaaccaggatat
cgtcacattcatctgctttctaaggatggcaccagcatacctccttcctcgctttttgtt
catatccggattacaaacttaacctga

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