Danio rerio (zebrafish): 565697 Help Entry 565697            CDS       T01004                                  Symbol pkd1b Name (RefSeq) polycystin-1 isoform X1   KO K04985   polycystin 1 Organism dre  Danio rerio (zebrafish) Brite KEGG Orthology (KO) [BR:dre00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:dre03037]     565697 (pkd1b)    04812 Cytoskeleton proteins [BR:dre04812]     565697 (pkd1b)    04040 Ion channels [BR:dre04040]     565697 (pkd1b)    04091 Lectins [BR:dre04091]     565697 (pkd1b) Cilium and associated proteins [BR:dre03037]  Primary cilia and associated proteins   Other primary cilia associated proteins    565697 (pkd1b) Cytoskeleton proteins [BR:dre04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     565697 (pkd1b) Ion channels [BR:dre04040]  Voltage-gated cation channels   Transient receptor potential channel (TRP)    565697 (pkd1b) Lectins [BR:dre04091]  C-Type lectins   Others    565697 (pkd1b) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PKD REJ PKD_4 PKD_channel PLAT Polycystin_dom Ion_trans Y_Y_Y Lectin_C DUF2807 GPS DpnI Motif Other DBs NCBI-GeneID:  565697 NCBI-ProteinID:  XP_021335980 ZFIN:  ZDB-GENE-100707-2 Ensembl:  ENSDARG00000033029 UniProt:  A0A8M9QMX0 LinkDB All DBs Position 12:23451577..23507587 Genome browser AA seq 4007 aa AA seqDB search MANILHLPLIWILCVFTSCFSEKDCPKGAKIDRDGLRCYWMPSFTSTWLEARGICQRDER GGDLALVDSVTVQSFIQNSFRLEDPVGVWMREGMAEGLFGDLDAEDREKKCFSMALASGQ WMNEQCNKRNFVICEKTISVSLPSLESYVTGVPLMSGVYTVSQIQLLPSPPDPGPHLVEI MLFPGLWFSHEGRVLSLEMVTQPSDQMTFARMQILRPYCSPSHHLVPPGCSSLLNPFSCC SLMAMCNTTGGCSSGQYWCHLLEICLPVTSPCSPYNSFNAGHDFALPPRYPVTPPFFHLM ADMSLMLPPSSEHTHIRATVQDKHITVYPDDILALQHNRRAGEFLHCVASTSSAWRQSYL SLPGPEWGGWFEGSFSVQPGKGQWLDGVICDLQVIYEDPMPHYVISPTPNSPMNAESPVT GLQVLHPKLDKNNQMYVPVNVTTLIVIRIISGEHVTSSWSAPVSKSGVPFVSSCPVEMPE TEEGGWFSHVYMELSGQEEYILNIKASNSLSAQTLSVRVVSHIPVSGLSIMPEGFRRVLV DIQQVFTASVTTGSSVTYSWVIDDLVQFAHTGESYSVVFKNPAEYTLKVMAHNPVSSQLM KVKLIADVMTPLDDLIVISMPEAIAVNTSTRYTIQVKADISIGVTIRWDFGDNTASVSHT VSPSSEIEELQQRAKHVYLQDSIQHTFASPGDYTLKIKAYNKYDQIEKAETVKVRTPISN LLVSSSPAVCQVNYTVLFEVSLWPSSFGALYSWNFSDDCEKVKEVYNKVSHVFNKPGTYN VTIMANNTLSTLTNYTAVEVIEPVSGLQLNYNISIELNSAFKISGKVSSGTHLKWTFEFG DGTTVINHTGSSASHMYESPGNYTVQVSAYNSVSQEHQLVSIEVYCLIITQITPTDCVLS QTEIDFEVLVKGFIPALTFEWEFGDGTPLSVVKGATSVTHTFKTAGTYTVGVNAHSLVTS VYYESSICVEGQITDVSLSSPNSAVAVSEVICFDASVLPKVTEYQFWWHNNFSSDTNPVK GLSHHCFMFQEEGLCEISVLVYNKVSNGTAKTIILVQRAVSNLCIKYEGNHDAMTVNQSY HFWAELLGKMASFQWDFGDGSKTEGQNQLHIFGFPGQFHVTVTASNAVSSDSVTVEIEVQ APLSYVMVNTSRPFVEAGKEILITALTDVRENISFFWTVNPSTPPKIGTSTFTHVFPNAG VFEIQVAAQNLVSRVEAITHIEVVEKIYGVWIQGQGLRSEKYFLTNQTILLEASVTHGSN LTYKWTANNSMAGNTKQFPLFTKNSGDIHVRLVVSNALGLVDSELSLRSVELVSGLSIVS PVKTVTKGKPVNISAILASGTDIKYSWFLDCEHCPVISDVPFILHAFKICGVVKIRVSAS NVFGSEEATKLLTIEENISKVDFQINGQSRPFFVKSNHLLMLFGSAGPGNVLHWEWVLTL HNRTVVVLTDNQTVSYSFVDAADHRLSLNASNDISWQTVSYTITVQDAIQGLSLTSSSSV VCEDDSVTFLTSVSKGSEVSVSLEFVNASYSVDIGRDFTTYSLAVGNHLVRATAKNKVSS QTATATVRVVERIRDLRLIGCCSAVLEASKNISFQASAFSQANYHWTFLLNGVQSSREIG QHVHFTPFANGSLSVTVEAENGFCSQSLTSTATIQKHLKKVTLLTSHDGAFIDYPVTFVA ITDGGSDLKFIWDFGDASEGLLVTDYNKQVHKYNVAGEFLVKVTAFNNISEVSVQIAIEV QNLVCTQPHIYTVKEEYNVLKSRPSFFEARVDFNGCVTHKASYIWEIFRGPDCPGMNKVN LNHSVDVTTPLLSLPKHTLKVGNYCLTFTARLKGTPLQQNKTIKLNVVHSRLIPVIKGGS LRLWSCLCDLTLDATESFDPDSEKNDIDLFKFQWSYTIENTTALSLAISTLHGHISGNSS MLILPRSVLLPDRVYRFTLTLFKSGRQPASISQSVRVYNATLLTVTVKCVSCNNQLFHMN HNDHVSLAGYCSSCQDTIQYRWTAENQRGEALTLNEVTTLTGSLRREIVIKPGVLMEGQE YTFTLNVSDPASGLWGSASITLVSNHPPYGGFCTLSPDDSLYFLETKVSYSCSGWMDDDG DSAQLIFSLQVAQCEDFGPLCPLITLYRGTQSTLSSLVPLGIKNTVENASVIHVLVHIED SMGATVVAVKKKLTVLPCDQCTVTWLKKRSQSEFWALIQQGNPQDIMQYSFALTSQLNQL TSISAQELEDKIHIRTRVIQVLASLPVSSLQDVALISSALAQSTVVPSEVQCSGCYAKVL QVTKKMIKVIREQTGEGNINPTDTGRNILTVLSNTMTADLRQRSTPDTSEHIRAVSALGQ VFELMRSLMLSRMRGGTALFLAIPKISAVGIQGDPTEDLRCKDVLTHCQFHIPPALSSQL KEEKQEVLQILLQMENEENPFIPGAEPPISTMLAAMEFATPQGNPISIANLTLDSAIQVT LHKQAQEMKDESLLWKNITLKHNGSVNFTVKAMDAEPHTGLYVALNFSLIPGSAEKASGL VWISINDQPVDLQSGRIHHQELTIFLSAQTPLLQHIIFLTPLLNGSAKELFVKVNSSIGG VDVTVSVCVFSVLCRFFDVKELRWSSDGLSPLSTSSPHSAHCLTQHLTMFGASLFIHPEA LLLLPPSEEPVRNVVVGIICGVLLLIHLLVGLMAHKLDHLENLRLCWVPLCGQKGRYQYR VLVKTGWKRGSGTTAHVGISLYGLNKSGSRHLQRQGAFQRNSMDDFQVETDANLGEIWKI RIWHDNTGLDPSWYLQHVIVWDIQTENMFFFLVEDWLSVENEKNSGRVEKVILASCPQEL HQFKRILHSQLLFGLQEHHLWISLWERPTHSRFSRAQRVTCCALLLHLYLAAGAVWYGAV GRKGSSGRVSTQMVMNAETVLVGMTVAALTFPFQAILKFLFQRTKSKVTLEVSAPPSPVS HTVEMDVFLSHPDLTCSSFLSLPTCPKSSIYDGPSPFTNSLQSKKLDSEFWNSPDPRNGR VDQLPSCDSIFGLPELTGTTHLLKRKKALLQLHLSTPTSDHDNGELAKSSASEEDLRTIS PDMDLTNTLSSDPEASDSGNFTPNDTIPTDTQDSFCSEWSDLSVDTPTYEPGFHRSSSSL SVLSEASTFLPSLPPDSISTVSTTRIGVVRGVPGFYLPSWVLRMVHLLVAVLLGTCLAVV GLYGSSFTSSVVLMWLVSTLSAVLTSALLLEPLAICIQALYLATVVRPVDPEVEERLAQE TEVRRSEEDFRDKVHPLCGYGLLQAKEEARKLRTLRALMRSCLVYMLFLLVVLMVNYQEH VQMADSRRLHSAIKHTLISASAGKPGLMKLSGWMNAEQWINEKLTSHLYENPSLLLTGPA RLQKVYFQDFCSQGIRDQFQSGRLSLMPTAHVSSHANPGQQTSTAHSKNTPALSTWQKRA LCAFSQTEELVLGNNTEYTRQILSDLQKEKWMTTGTKAVLIEFTQYHKQTSILAPVSILL DQTQTGRILAFISIQPFHISPLSGPDLHVTLTVVLLLFALCFLSTEVRALIRKPSQYLRQ AWCWFQTLLALLALAAAVLRLYFLYTTTVCISRYRSIPSSFADFHSAATVARKSNQLSAI LLTLLALKMVGILQFVRRWLVMGRVIWQVFPQICGVVFLLLLLLLLFSHIGMMLFSGSVE GFRTLGQASSSLLCLLRGRTGLQRLCEHHPVVGPLYCLSAVGIGFWVLGRLCAAVLIRTY QMVQADIYRPSMEPQDYEMVQFLIKRLKLWMGLSKTKEFRHRVKFEGMRPPPSRSSQVSA SSNCWTPLSPIGSRQTLLSSASSLASDTSVISDSCDVHPYVERLVPCVDSLLAGFERVNQ VTEEVYNFELQLQQIQSRISQIRKLPLPVTFTECDLTPKPPLLPRHPSSSVLESKPSPSC LLNTLPYRRAAHSESSLMGPAVQLGRRILSALDGGRMNSPNPRKRVVPRQRAWNSVTCHS ADTAQWIAGFHNTDGPLVRPQSQDEDRQRGCEGMPIKRRAWQTEKEL NT seq 12024 nt NT seq  +upstreamnt  +downstreamnt atggcaaatattctccacctgcctctcatttggattctctgtgtttttacaagctgcttc agcgaaaaagattgcccaaagggagcaaaaattgaccgtgatggtttgcgctgttactgg atgccctcatttacgtcaacatggctggaagcaagaggcatctgtcagagagacgagaga ggaggagaccttgctttggtggacagtgtgactgttcagagcttcatacaaaattcattc cgtctcgaagatccagttggggtctggatgagggaaggcatggcagagggtttgtttggt gatttagatgctgaagaccgtgagaaaaaatgtttttcaatggctctggcctctggacag tggatgaacgaacagtgtaataaaaggaattttgttatctgtgaaaaaacaatatcagtg tctttgccgtcgctggagagttatgtgactggtgtaccactaatgtctggcgtatacaca gtgtcgcaaatacaactgctaccctctccaccagacccaggaccacacttggttgagatt atgctgttcccaggtctgtggttcagtcacgagggtcgagtgctgtctttggaaatggta actcagcccagtgatcagatgacctttgccagaatgcagatcttacggccatactgcagc ccaagtcatcaccttgttccacctggttgcagttctctcctcaaccctttcagctgctgt tccctgatggccatgtgtaacaccactggcggctgttctagtgggcaatactggtgccat ctgctggagatctgtctgcccgtcaccagtccatgcagcccttacaactcttttaacgct ggacatgatttcgctttgcctccccgctatcctgtgacgccaccattcttccacttgatg gcagacatgtcactgatgctgccaccaagcagtgaacacacacatatcagagctacagta caagacaaacacatcactgtttatcctgatgacatcctggctctgcaacacaatagaaga gcaggtgaatttctccactgtgttgccagtaccagctcagcctggcgccagagttacctc tcccttcctgggcctgaatggggtggctggtttgagggtagtttctctgttcaaccagga aaaggacaatggctagatggagtcatctgtgacctccaggtcatttatgaggacccaatg ccacactatgtaatttcaccaacacccaacagtcctatgaatgcagaaagtcctgtgacg ggcttacaggttttgcatccaaagcttgacaagaacaaccaaatgtatgttcctgtcaat gttacaaccctcattgtcatccggatcatttcaggagaacatgtaaccagctcctggtcg gcaccagtatcaaaaagtggtgtaccatttgtgtcttcatgcccggttgaaatgcccgag actgaagaaggtggatggttttcacatgtgtacatggagctttctggccaagaggaatat atattaaatattaaggcttcaaacagcttgagtgctcagactctgagtgtgagggtcgtg tctcatattcctgtttctggactgagcatcatgccggagggcttcagaagagttttagtg gacatacagcaggtgtttacagcttcagtaaccactgggtcatcagtgacgtattcttgg gttattgatgacctggttcagtttgcacacacaggggagtcttatagtgtggtttttaaa aacccagcagaatacacgcttaaggtaatggcgcataaccccgtgagctctcagttaatg aaggtgaagctcatagccgatgtaatgaccccattagacgacctaatagtcatttccatg ccagaggctattgctgtaaacacctcaactcgctatacaattcaagtcaaagctgacatc tctataggcgttacaatcagatgggattttggtgataatacggcatctgtcagtcatact gtttcaccttcttcagagattgaagagcttcagcaaagagccaaacacgtatatctgcaa gactctattcagcatacattcgcttctccaggtgactacacactaaaaataaaggcgtac aacaagtatgatcaaattgaaaaggctgaaacagttaaagtaaggactccaatctcaaac ctgctggtgtcttcatcgcctgctgtctgtcaagtcaactacactgtcctctttgaggtc tctctctggccgtcttcatttggagcactttattcatggaattttagtgacgactgtgaa aaagtgaaggaagtttacaacaaagtcagtcatgtttttaataagcctggcacatacaat gtcaccatcatggctaacaacaccctatccaccttgactaactatacagcagtagaggtt attgagcctgtttcaggtctccagttaaactacaacatctccattgaactcaactcagcc tttaaaatcagtggaaaagtctcttcgggtacccatctaaaatggacctttgaatttgga gatggtactactgtaataaatcatactggaagttcagcctctcacatgtatgagtctcct ggaaattacacagttcaggtttccgcttataattcagtaagtcaagaacaccaattagtc agtattgaagtttattgcttaataattactcaaataacacccacagactgcgttttgagt caaacagagatcgattttgaggtgttggtcaaaggctttattccagctttgacttttgaa tgggagtttggagatggcacaccattgtctgttgtcaaaggagctacatctgtaactcat acttttaaaacagcaggaacgtacacagttggtgtaaatgcgcacagcttggtgacttca gtctattatgaaagcagcatatgtgtggagggccaaataacagatgtttctctgagttca cccaatagcgcagtagcggtgagcgaggtaatatgctttgatgcttctgtgcttcccaaa gtaacagaatatcagttttggtggcataataacttttctagtgacacgaaccctgttaaa ggtctgtcacaccattgctttatgtttcaagaggagggtttgtgtgaaatttcagtgctg gtatataacaaggtgagcaacggaacagcaaaaacaatcattttagttcaaagggctgta tctaatctgtgcataaaatatgaaggcaaccatgatgcaatgactgtgaatcagtcctat catttctgggctgagcttcttggtaaaatggcatcatttcagtgggactttggtgatggc tctaaaacagaggggcaaaatcaattacacatttttggttttcctggacagtttcatgtg acagtcaccgcatctaatgcagtaagctcagattcagtgactgtcgagattgaggtgcag gcacctctgtcatatgtaatggttaataccagtcggccattcgtggaggcaggaaaggag atactgataacagctctgacggacgtgagagaaaatatttcatttttctggactgtgaat ccttcaacgcctccaaagatcgggacgtccacattcacgcatgtgtttcccaacgcaggg gtgtttgagattcaagttgcagcacagaatcttgtcagtcgtgtggaagcaataacacac attgaagttgtagaaaaaatatatggagtttggattcaaggccaggggctgcggtctgaa aaatatttcctgacaaatcaaacaatactgttggaagcatcagtgacacacggttctaac ttgacatataagtggactgcaaacaatagtatggcaggcaataccaaacaatttccactt ttcacaaaaaattctggtgacatacatgtcaggctggttgtgtccaacgcactcggatta gtagatagtgaactttcactcagatcagtagagcttgtgtctggcctgagtattgtatcg ccagttaagactgtaacaaaaggaaaaccagtgaacatatctgcaattttagcatctgga acggacattaagtactcatggttcttggactgtgagcattgtcctgttatatcagatgta cctttcattctacatgcttttaaaatctgcggagtggtcaagattagagtatcagcctca aatgtgtttgggtctgaagaagcgactaagctgctaacaattgaggaaaacatctctaaa gtggactttcagataaatggccaatccagaccattttttgtaaaatcaaaccacctactg atgctctttggctcggcgggaccaggaaatgtcctgcattgggaatgggttttaacattg cacaatagaactgttgtggttcttaccgacaatcaaactgttagctattcttttgtggat gctgcagatcatcgtctctcactcaatgcttcaaacgacattagctggcaaactgtttca tatactatcacggttcaggatgccatccaaggactttctcttacatctagcagcagtgtg gtctgtgaggatgattctgtgactttcctaacatctgtctccaagggaagtgaagtttca gtttctttggagtttgttaatgcaagttattctgtggacattgggcgggattttaccacc tactctcttgcagttggaaaccatctggtaagagcaacagcgaaaaataaagtcagtagc caaactgcaacagcgactgtgagagtcgtggaaagaattcgagatctgcgtttgattgga tgctgctctgccgtcttagaggcatccaaaaacatcagcttccaagcatcggctttctcg caagccaattaccactggaccttcctattaaatggagtccagtcctctcgggaaattggg cagcatgttcacttcacaccttttgctaatggatccctgtctgttacagtggaagctgaa aatggattctgctcacagtccctgaccagtacagcaacaattcagaaacatctgaagaaa gtgactcttttgacctcccatgatggagcttttattgactatccggtcacttttgttgcc atcacagatggaggcagcgaccttaaattcatttgggatttcggtgatgccagcgaagga ctcctggttacagattacaataaacaagtccacaaatacaacgttgctggtgagtttttg gtgaaagtgacagctttcaataacataagcgaggtctccgttcaaattgcaatagaagta caaaatctggtgtgtacccagccacatatctatactgtaaaagaagaatataatgtttta aaatccagaccaagtttctttgaagcaagagtggacttcaacggttgtgttacacacaaa gcatcttatatctgggagatcttcagaggtccagattgcccaggaatgaacaaggtgaat ttaaatcattcagtggacgttacaacacctctactctctctgccgaagcacactctgaaa gtgggaaactactgtctgacatttactgccaggcttaagggaactcctctacagcagaac aagaccataaagctgaacgtggtccacagtcggctgatacctgtgattaaaggtggttca ctaaggctttggtcttgtctgtgtgatctgacactggatgcaacagagtcttttgatcca gattcagagaagaacgatattgacttgtttaagttccagtggagttacacaatagagaac acaacagcactttctttagccatttccacccttcatggccatatttcaggaaatagcagt atgctgattcttcccagaagtgttctgctgccagacagagtgtaccgctttactctaacc cttttcaaaagtggacgacaacctgcctctatatctcagtcggttagagtgtacaatgcc acattactaactgtgactgtgaagtgtgtttcttgtaataaccaattgtttcacatgaat cacaacgaccatgtttccttggctggctattgttcttcatgtcaggacaccatacagtac agatggactgcagagaatcagagaggtgaagctcttacactgaatgaggtcactaccttg acaggaagcctccggagagaaatagtcattaaaccaggggtgctaatggagggccaagaa tacacctttactctcaacgtgtctgatcctgcctctgggctttgggggtcggcaagcatc accttagtttccaaccatcctccctacgggggtttttgcactctgtcacccgatgactcg ctttatttcctggaaaccaaggtttcttacagttgctctgggtggatggatgatgacggt gactcagctcagctcatattttcactgcaggtggcacagtgtgaagatttcggaccatta tgtcctttgattaccctttacagaggcactcagagcacgttgagctccctggtgccactg ggtattaagaacacagtggaaaatgcatctgttattcatgtgctggttcatatagaggat agtatgggggctacggttgtcgcagtaaaaaagaaactgacagtgttgccttgtgaccag tgcacagtgacatggttgaagaaaaggagtcaatcagagttttgggccttgatccaacaa ggcaaccctcaggacattatgcaatattcttttgccctgaccagtcaactcaaccagcta acatccataagtgctcaggaactggaggacaagattcatatacgtacaagggtgatccaa gtcctggcctctcttccagtctcctcactccaggacgtggctcttatcagctcagctttg gcccagtctacagtggttccctctgaagtgcagtgcagcggctgctatgcaaaggtcctg caggtcacgaagaagatgatcaaagttataagagaacaaactggagagggcaacatcaac cccacagacaccggcaggaacatcctgactgttttaagcaacacaatgactgcagatctg aggcaaaggagcactccggacacatcagagcacatcagagccgtatcagcactgggacag gtttttgaacttatgcgttcattaatgttgtcacgaatgagagggggaacagcacttttt cttgccatcccaaagatcagtgcagtgggcattcagggtgaccctactgaagacctccgg tgcaaagatgtcctcactcactgtcagtttcacataccaccagcactgagctctcaactg aaggaagaaaaacaagaggtcctgcagatcctgctgcagatggagaatgaagaaaatcca ttcattccaggtgccgaacctcctatatccaccatgctggcagccatggagtttgctaca ccacaggggaaccccatttccattgccaacctgacactagattctgccatacaagtcaca ttacacaaacaagcacaagagatgaaagatgagagcttactgtggaagaatattactctg aagcataatggaagtgtaaatttcacagttaaagcaatggatgcagaacctcacactgga ctctatgttgccctaaacttcagtctcattccaggatctgctgagaaagcctctggacta gtatggatctccattaatgaccaacctgtagatttacagtctggacgcatacatcatcaa gaactcaccatttttctctcagctcagactccgctactgcagcacatcatcttcctcaca ccactcttgaatggctctgcgaaagagctgtttgtgaaggtgaacagcagcatcggcggt gtggatgtgactgtgtcggtgtgtgtgttcagcgtgttgtgccgattcttcgatgttaaa gagctccgctggagcagtgatggtctgagtcctctgagcaccagcagtcctcactctgcc cactgcctcacacagcacctcaccatgtttggagccagtctcttcatccatcctgaggct ctgctgcttctgccaccgtcagaagagccagtgagaaatgtggtagtgggcatcatttgt ggagtcctgctgttgattcaccttctggttggtcttatggctcacaaacttgaccacctg gaaaatttgcgtctttgttgggttcctctgtgtgggcagaaaggtcgctaccagtaccgg gttcttgtcaaaacaggctggaaaagaggctctggtaccactgcacatgttggcataagc ctgtatggtctgaataaaagtggctcacggcaccttcaaagacaaggagctttccaaagg aacagcatggatgacttccaagttgaaacagatgccaatcttggagagatctggaaaata cgcatctggcatgacaacacaggtctagacccatcttggtatctacaacatgtaatagtt tgggacatccagacagaaaacatgttcttcttcttggtggaagactggctctcagtggag aatgagaaaaactctggaagggtggagaaagttatattagcatcttgccctcaggagctg catcagtttaagagaatcctacattcccagttgctgtttggacttcaagagcaccatctg tggatttcattatgggaacggccaacacatagccgctttagccgagcccagagggtcacc tgctgcgccctcttattacatctctatctggcagctggggcagtatggtatggagcagtg ggcagaaagggcagcagcggtcgagtttctacccagatggtgatgaatgcagagactgtt ctggttgggatgacagttgcagctttgacattcccttttcaagccattctcaaatttctc tttcaaagaaccaagagcaaggtgacactggaggtgtctgcgcctccttctcctgtgtct cataccgtggagatggatgttttcctcagtcacccagatctcacctgctcatcttttctg tccctgccaacatgccccaaatcttctatttatgatggaccatctcctttcacaaattca ctgcagagcaagaaactagattcagagttttggaactctccagatcctaggaatggccgt gtggatcaattgccgtcatgcgacagtatctttgggctgcctgagctgacaggaaccaca caccttctaaagagaaaaaaagcccttctacaattacatttgtctactccaacatctgat catgacaatggagaactagccaagtcttcagcttcagaggaagatttgaggactatctcg ccagacatggatctgacaaacacgctttcctcagatccagaagcatccgacagtggcaat tttacacctaatgacaccattccaactgacacccaggatagcttctgtagcgagtggtct gatctgagtgtggatacacctacatatgaaccaggatttcacaggtcctcctcctcactt tcagtgctcagtgaggctagcacatttctccctagtctcccacccgactccataagcacc gtctccaccacacgcattggtgtagttcgtggtgtacctggcttttatctgccctcatgg gttctgcgcatggttcacctgctggtggctgttctgctgggaacgtgtctggctgtggtg gggctgtacgggagcagcttcaccagctctgtggttctcatgtggctggtgtccacacta tcagccgtcctcacttctgccctgctgctggaaccactagcaatatgcattcaggcacta tacctggctactgtggtgcgaccagtggatcccgaggtggaggagcgtttggctcaggag actgaggtcagaaggtctgaggaggacttcagggataaggtgcaccctctctgtggatac ggcctactgcaggctaaagaggaagcacgaaaactgaggacacttagagccttaatgagg agctgtttagtgtatatgctcttcctgttggtggttctgatggtgaactatcaggaacat gtgcagatggctgacagtagacggcttcactccgccattaaacatacactgatctcagct tcagcagggaagcctggtctcatgaagttatcaggatggatgaatgcagaacagtggata aatgagaaattaacatcacacttatatgaaaacccttctcttcttttaactggccctgca agactacagaaagtttattttcaagacttttgcagtcaaggcatcagagaccagttccag tctggccgactttctttgatgccgactgctcatgtttcatcacatgccaaccctggacag cagacctccacagcccacagcaaaaacactccagcgctgtcaacatggcaaaagagagca ttatgtgcattcagtcagacagaagaactagtgcttgggaacaatactgaatatacacgg cagatcctgtcagacctgcagaaagagaagtggatgacaaccggtacaaaggctgtattg atcgagttcactcagtatcataaacagacaagcatcttggcaccagtctctattctcctg gatcaaacacagacaggcagaatccttgctttcatctccatccagccctttcacatctct ccactatctggtccagacttgcatgttactctgacggttgtgctactgctattcgccctg tgctttctgagtactgaagtgcgagccttgatcaggaagccaagtcaatacctgaggcag gcctggtgctggtttcagacactgttggcacttctggctttggcagctgctgttctacgt ctgtatttcctctacacgactacagtctgcatttccagatatcgttcaataccctcctca tttgctgacttccatagcgctgccacagtggccagaaagtccaatcagctctcagcaata ttattaaccctcttggctctaaagatggtgggaatcctgcagtttgttaggcgatggttg gtcatgggacgggttatttggcaggtatttcctcaaatctgtggtgtggtgttcctgctg ctcctcctgttgctcttgttttctcacataggcatgatgctcttctcaggatcagtggag ggctttaggacactgggacaggcgagctcctctctgctgtgtctgttaaggggtcgcaca gggttgcaacgactgtgtgagcatcatccggtggtgggacctttatactgcttgtctgct gtgggtattggattctgggtactgggacgcctatgtgctgctgtattgattcgaacttac caaatggtacaagcagacatttaccgaccctccatggagccacaggactacgagatggtt cagtttcttattaaacggctcaagctgtggatggggctcagcaaaaccaaagagttcaga cacagagtgaagtttgagggaatgcgtcctccaccctccagatcctctcaggtctctgca agctctaactgctggaccccactaagccccatcgggtcccgccagacactattatcatct gcctcctctctggcctccgacacatccgtcatttcagacagctgtgatgtccacccttac gtggagcgcctggtgccctgtgttgacagccttttggcgggtttcgagcgtgtcaaccag gtgacggaagaagtatataactttgagcttcaacttcagcagattcagagcaggatctct caaataagaaagctgcctttgccagtgacctttacggaatgtgatctaacaccaaaacct ccattgctccctcgacacccatcatcctctgttttggaaagtaagccctctccatcttgt ctactgaatactcttccatatcggcgagctgctcactcagagtcctcgctgatggggcct gctgttcagctgggaaggagaatactatctgcactggatggaggaagaatgaacagtcca aaccctagaaaaagggtcgtcccaagacagagagcctggaattcagttacctgccattct gctgacacagctcagtggatagctggatttcacaacactgacggccctctagtgagaccc cagagccaagacgaagacagacagcgtggatgtgaaggaatgccgatcaagagacgagca tggcagactgaaaaagagctttaa

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