Danio rerio (zebrafish): 569877 Help Entry 569877            CDS       T01004                                  Symbol top2b Name (RefSeq) DNA topoisomerase 2-beta   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism dre  Danio rerio (zebrafish) Brite KEGG Orthology (KO) [BR:dre00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:dre03032]     569877 (top2b)    03036 Chromosome and associated proteins [BR:dre03036]     569877 (top2b) Enzymes [BR:dre01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      569877 (top2b) DNA replication proteins [BR:dre03032]  Eukaryotic type   DNA Topoisomerases    569877 (top2b) Chromosome and associated proteins [BR:dre03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     569877 (top2b)   Centrosome formation proteins    Centriole proteins     569877 (top2b) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim HATPase_c_3 Motif Other DBs NCBI-GeneID:  569877 NCBI-ProteinID:  NP_001038656 ZFIN:  ZDB-GENE-041008-136 Ensembl:  ENSDARG00000034195 UniProt:  Q1LUT2 LinkDB All DBs Position 19:complement(18850084..18947226) Genome browser AA seq 1618 aa AA seqDB search MSNGAAGSGGLTWVTLFDKNNGAKKEEMNGRGDAGKSEVVKKESSKKMSVERIYQKKTQL EHILLRPDTYIGSVEPVTQQMWVFDEEIGMNLREISFVPGLYKIFDEILVNAADNKQRDK NMTTIKITIDPESNTISVWNNGKGIPVVEHKDEKMYVPALIFGHLLTSSNYDDNEKKVTG GRNGYGAKLCNIFSLKFTVETACKEYKRSFKQTWTENMGKSNEAKIKYFDGEDFTCVTFQ PDLAKFNMEKLDKDIVALLTRRAYDVAGSCRGVKVILNGKKLPVNSFRSYVDFYVKDKLD ETGVALKVVNETVNERWEVCLTMSEKGFQQISFVNSIATTKGGRHIDYIVDQIVGKLIEV VKKKNKAGVSVKPFQVKNHLWVFVNALIENPTFDSQTKENMTLQTKSFGSKCALSEKFIR AATNCGIVESILNWVKFKAQTQLNKKCSSVKHSKIKGIPKLDDANDAGGKHSSECTLILT EGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREATHKQIMENAEINNIIKILGLQYKK SYDDPESLKSLRYGRIMIMTDQDQDGSHIKGLLINFFHHNWPSLLKHTFLEEFITPIVKA SKNKQEVSFYSIPEFEEWKKHTESYKTWHIKYYKGLGTSTSKEAKEYFSDMERHRIMFKY NGTEDDAAITLAFSKKKTDDRKEWLTNFMEDRRQRRMHGLPEQYLYGTSTRHLSYNDFIN KELILFSNSDNERSIPSLVDGLKPGQRKVLFTCVKRNDKREVKVAQLAGSVAEMSAYHHG EQALMMTIVNLAQNFVGSNNVNILQPLGQFGTRINGGKDAASPRYIFTMLSPLAKLLFPA VDSSLLKFLYDDNQKVEPEWYIPIIPMVLVNGAEGIGTGWACKIPNYDPREIVNNINRML NHQDPLPMLPSYKNFKGTIHELGQNQYLVSGEVSVLDKNTIEISELPVRTWTQAYKESVL EPMLQGTDKTPPLISDYKEYHTDTTVKFVVRMTEEKLAQAEAAGLHKVFKLQSSLTCNSM VLFDHMGCMKRYESVQEILKEFFELRLHYYKLRKDWLVGSLGAESAKLSNQARFVLEKIE GKLSIENKSKRDLIRMLVQRGYESDPVAAWNKAQEKSLEEEDGGGNDSDSSVDSGSFSGP NFNYILNMPLWCLTKEKVEELLKQRDLKKAELNELQSKTSENLWREDLAVFIEELDRVEE QEKESVNLGKAVKLVKGKVGKPKVKKMQLEETLPSPFGRRVEPQITLAMKADASKKLTKK KKGEIDAAVKLEIDDDSALGSNGGENSLISPSGLPNPGAKPKAPRVKREKKEPGTPRQRK PAGAKGPAKKVKKRNPWSDDDEGGDDDRSDIELDECEPVIPRDSTSRRASAVKAKYTFDF SEEEEEEEDGDEEQENDASASPVHSFKNTEQHDDEVDDDDDIFPPKTTFTLPTSTAKKKN PEPVLPSKTTYDDKISDDDMKSDSDGDRGPVFSSYSSSSAFEKPAKKTAKKPVDTPPKPK KAPVKAKKPDTSVWDSDSDTGTKKPPASKGSGKGRSKKRKQSSLEEDEYSPMKKHGKSAT SRKPKKAASDDEDDDDDDETGFNSFSHLDSGRDRSGRAKKEVKYFAESDNDDDDDMFD NT seq 4857 nt NT seq  +upstreamnt  +downstreamnt atgtctaacggtgctgcggggagcgggggcttaacatgggtgaccctctttgacaagaac aatggtgcgaagaaagaggaaatgaatggccggggagatgcaggaaaaagtgaggtggtg aagaaggagagttctaagaagatgtcagtggagaggatctaccagaagaagacccaacta gaacacatccttctccgcccagatacatatattggctctgtggaacctgtcactcagcaa atgtgggtttttgatgaagaaattggaatgaacttgagagagatttcgttcgtccctgga ttatataaaatctttgatgagatccttgtcaatgcagctgataacaaacagagagacaag aacatgacaaccatcaaaatcactattgacccagagtccaacactatctctgtgtggaat aatggaaaaggaattcccgtggttgaacacaaagatgagaagatgtatgttcctgcactg atctttggacacctgctcacctcgagcaactacgatgataatgagaaaaaagtcacaggt ggcagaaatggatatggcgctaaactatgtaatatatttagcctaaaatttacagtggag acagcctgcaaggagtacaaacgcagtttcaaacagacatggacagaaaacatggggaag tcaaatgaggcgaagattaagtactttgatggggaagacttcacatgtgtcactttccag cctgatctggctaaattcaacatggagaaactagacaaggacattgtggctcttcttaca cgcagggcatatgatgtggctggctcttgtaggggtgttaaagtcattctcaatggaaag aagctacccgtgaatagtttccgcagttatgtggatttctacgtaaaggacaaactggat gagacaggtgttgctctgaaggtggtaaatgagactgttaatgaacgctgggaagtgtgt ctcaccatgagtgaaaagggcttccagcaaatcagctttgtcaacagcattgccaccact aagggaggaagacatatcgattatatagtggaccaaatagtggggaaattgattgaagtt gtgaagaagaagaacaaagccggagtatctgtaaaaccattccaggttaaaaaccatcta tgggtatttgtaaatgcccttatcgagaacccaacctttgattctcagaccaaggagaac atgactctacagaccaaaagcttcggttccaaatgtgctctctcggagaaattcatcaga gctgccacaaactgtggtatcgtggaaagcattcttaactgggtgaagtttaaagctcag acacagctgaacaagaaatgctcctctgtcaaacacagtaaaattaaaggtattcccaaa ctagatgacgccaatgatgcagggggcaaacactcttcagagtgcacactgatccttaca gagggagattcagccaagtccctggctgtatctggtttaggtgtaattggtcgggaccga tatggagtgtttccccttaggggaaaaatcctcaacgtgagggaggccacacataaacag atcatggagaatgcggaaatcaacaacatcatcaaaattttgggtcttcagtacaagaag agctatgatgatccagagtccctgaagagcttacgctatggaaggattatgatcatgaca gatcaggatcaagatggttctcacataaagggtcttctgattaacttcttccatcataac tggccatccctgctgaagcatacctttctggaggagttcatcacacctattgtgaaggcc agtaagaataaacaggaagtatcattctacagcataccagagtttgaagaatggaagaag catacagaaagttataaaacttggcacataaagtactacaaaggtttgggtaccagcaca agcaaagaagcgaaggaatatttttcagacatggaaagacatcgcattatgttcaagtac aatggtactgaagatgatgcggccattacactggctttcagcaagaagaaaacggatgac aggaaagagtggctgactaatttcatggaggacagacgacaaaggaggatgcatggactt cctgagcaatacttgtatggcacatcaacacgacacctgtcctacaatgacttcatcaat aaagaactcatcctcttctccaattctgacaatgagcgttcaattccatcacttgttgat ggtctaaagccaggccagaggaaggtgttgtttacctgtgtaaaaaggaacgataaaaga gaagtcaaagtggcccagctggccggatctgtggctgagatgtctgcatatcatcatggc gagcaagccctgatgatgactatcgtgaatttggcccagaactttgtcggcagcaacaat gtcaacatccttcagcctctcggacagttcggtacccgtattaatgggggtaaagatgct gccagtcctcgttacatctttactatgcttagtccattggccaaactgctgtttcctgct gtggactccagtctgctaaagtttctatatgatgacaaccagaaggtggagccagaatgg tacatacccataattcccatggtactggtaaatggagctgagggtattgggactgggtgg gcatgcaagattcccaattatgacccacgagagattgtcaacaacatcaaccgtatgctc aaccatcaggatcctctacccatgcttcccagctacaagaactttaaaggtaccattcat gaactgggacaaaaccagtatttggtcagtggagaagtgtccgtgctagacaaaaatacc atcgagattagtgaacttcctgttcgtacatggactcaggcttacaaagagtcagttctg gagcccatgctccaaggaacagataaaacccctcctctgatcagcgactataaggaatac cacactgacactactgtgaagtttgtggtgcgcatgacagaggagaaactggcacaggca gaggcagccggtcttcacaaggtcttcaaattacagtcatcactcacctgtaactccatg gtgctgtttgatcacatgggctgtatgaagcgatacgagtctgtacaggagatcttgaaa gagttttttgagttgcgcctacattattataaattgaggaaagactggctggtgggtagt ttgggtgctgaatctgccaaactgtcaaaccaggcacgatttgttctagagaagattgaa ggaaaactatcgattgagaacaaatcaaaaagagatttgatccgcatgctggtgcaaaga ggatatgagtctgacccagttgcagcctggaacaaagctcaagagaagtctttggaggaa gaggatggtggtggtaatgacagtgacagctcagtggactctggctctttctctggacca aattttaactacattctcaacatgcctctgtggtgtctgacaaaggagaaggttgaggaa cttctcaagcagagagaccttaagaaagcagagctgaatgaactccagagcaagacttca gaaaatctgtggagggaagatctggccgtttttatcgaggaactggatcgtgtagaggag caggaaaaagagagtgtgaacttgggcaaggctgtaaaactggttaaaggtaaagtgggc aaacctaaagtgaagaagatgcagttggaggaaactctgccctctccatttggccgaagg gttgagccacagattacactggctatgaaagcagatgcctccaagaaactcaccaaaaag aagaagggtgagatagatgcggctgtgaagctggagattgatgatgacagtgctctaggt tccaatggaggagagaattccctaatttctccatctggccttcccaacccaggagccaaa cccaaagctccaagggtcaagagagagaaaaaagaacccggtacaccaagacaaagaaaa ccagctggtgctaaaggtccagctaagaaagtgaagaaaagaaatccatggtccgatgat gatgaaggtggtgatgatgatcgatctgatattgagctagatgaatgtgaacctgttatt cctagagacagtacatccaggagagcttcagctgtaaaagccaagtacacatttgacttc tctgaggaggaagaggaagaggaggatggtgatgaagaacaggagaacgatgcttcagca tcaccagtacactccttcaaaaacacagagcaacatgatgatgaagttgatgatgatgac gatatttttcctccaaaaacaacatttactttgcccacttcaacagcaaaaaaaaagaat ccagagcctgttttgccatctaaaaccacctatgatgacaagatcagtgatgatgatatg aagtcagacagtgacggtgacagaggtccagtgttctcatcgtactctagcagttctgct tttgagaaacctgctaaaaaaacagctaagaaacctgtagatacaccacctaagccgaag aaagctccggttaaagccaagaaacctgatacatccgtctgggactcagactcagataca ggcactaagaaaccaccagcatcaaaagggagtgggaaaggcagaagcaagaagcgaaag cagtcaagcttagaagaggatgagtatagccctatgaagaagcatggaaagtctgccaca agcagaaaaccaaagaaggcagcatctgatgatgaagacgatgatgatgatgatgaaacg ggctttaacagctttagccacctggactcaggaagagatcgttctggtcgagccaagaaa gaagtaaaatactttgcagaatctgataatgatgatgacgatgacatgtttgactaa

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