Danio rerio (zebrafish): 570437
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Entry
570437 CDS
T01004
Symbol
pfaS
Name
(RefSeq) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
dre
Danio rerio (zebrafish)
Pathway
dre00230
Purine metabolism
dre01100
Metabolic pathways
Module
dre_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
570437 (pfaS)
Enzymes [BR:
dre01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
570437 (pfaS)
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Paralog
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Tegument_dsDNA
Motif
Other DBs
NCBI-GeneID:
570437
NCBI-ProteinID:
NP_001038667
ZFIN:
ZDB-GENE-030131-4420
Ensembl:
ENSDARG00000003750
UniProt:
Q5TZ72
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Position
20:28121571..28148581
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AA seq
1314 aa
AA seq
DB search
MPVVRFYRTEETGEARAIRRIAQLYPDVIITTELCYNVELDGPDSLSVAQKDILRWLFSP
PYSVSLLEEPTLKAEHGARLVEIGPRLNFSTAWSTNAVSICQSAGLSQVTRVELSRRHLI
KPQEGCKVGMKDGEMESLISCLYDSMTECIYAQPITSFAVDIRPQDVFEVDILGKGRAAL
EKANDELGLAFDSWDLDYYTALFQKVKRNPTSVECFDLAQSNSEHSRHWFFRGRMVIDGK
EQKETLFSLIMGTQQHSNQNNVIKFCDNSSGIKGMELRCMYPTNPAQASPYESRDTTRHV
IFTAETHNFPTGVAPFSGATTGTGGRIRDVQSAGKGGHVIAGTAGYCFGNLHIPGFVLPW
EEEGWEYPSSFAPPLQVAIEASDGASDYGNKFGEPVLAGFARSFGMRLANGERREWIKPI
MFSGGLGSIEDPHVRKDQAEPGMEVVKIGGPVYRIGVGGGAASSVQVQGDNSSARDLGAV
QRGDAEMEQKMNRALRACLERVEGNPICSIHDQGAGGNGNVLKELSEPAGAVIYTEKFKR
GDPTLSVLELWGAEYQESNALLLRPSDRSFLERVCQREKCPVDFVGKITGDGKIVLVDGL
RKQNDVLEGARNPVDLELDWVLGKMPQKEFILEHRSVSLQPLTLPAGLSVLPALERVLRL
PAVASKRYLTNKVDRSVTGLVAQQQCVGPLHTPLADVAVVALSPFSLQGAATAIGEQPIK
GLLSPAAGARMAVGEALTNLVFARVSALKDVKCSGNWMWAAKLPGEGACLWDACQAMCEV
MGQLGVAVDGGKDSLSMAARVSGETVKAPGSLVISVYAVCPDITATVTPDLDNPEGKGVL
LYVPVSAGKYRLGGSALAQCFGQLGDCSPDMDQPDKLSACFNTTQTLIQDRLLTAGHDVS
DGGLISCLLEMAFAGNYGIEVDLPLEGVDVMEALFSEELSLVLEVCERNASSVCQRYTDA
GLLCHRIGTTSGFGPDAKVRVSLCGREVLNERLPTLRAIWESTSFELERLQANPLCVQEE
EQGLASRTQPYLKLTFDPSQTPIIKELATGKARVAVVREEGSNGDREMSASLFMAGFEVW
DVTMQDLCSGSTTLDPFRAVVFVGGFSYADVLGSAKGWAATVTFNNRAREEFERFRKRED
TLSLGVCNGCQLLALLGWVGEREDGGSDVTLTHNKSGRFESRFVSVGILPSPAIMLKGME
GSALGVWVAHGEGLMQFRSPEAQQKLIGSSLAPLRYVDDSGNPTEIYPINPNGSAQGVAG
ICSADGRHLAMMPHPERAVLSWQWAWAPQHLRGSLEPSPWLSMFRNAAAWCQNS
NT seq
3945 nt
NT seq
+upstream
nt +downstream
nt
atgcctgtcgtgcgcttctacaggacagaggagactggagaggctcgggccataagaagg
attgcacagctgtatccagatgtcattataacaacagagctttgctacaatgtagagctg
gatggtcctgattctttaagtgtagcacaaaaagacattttgcgctggttgtttagtcca
ccatattctgtcagtttgttagaggagcccactctaaaagcagaacatggagcaagactg
gtggagattggacccaggttgaacttctccactgcttggtccaccaatgctgtatccatc
tgccaaagtgcaggtctgagtcaggtgacgagagtcgagctctcccgcagacatctcatc
aagccccaggaaggatgtaaagttggcatgaaggacggagagatggagagtctgatttca
tgcttgtatgacagtatgactgaatgtatttacgctcagccaatcacatcgttcgcagtt
gatattcggccacaggatgtgtttgaggtggacattctgggaaaagggcgtgctgctttg
gaaaaggccaatgatgaacttgggttggcatttgactcctgggatctggactactacact
gcacttttccagaaagtgaaaagaaatcccacaagtgtagaatgctttgatctggcccag
tccaacagtgagcacagccgtcactggttcttcagagggagaatggtcattgatggaaaa
gagcagaaggagacgctcttcagcctcattatgggcactcagcagcacagcaaccagaat
aatgtcatcaaattctgtgacaacagcagtggtattaaaggcatggagctgaggtgcatg
tatcccacaaaccctgcacaggccagtccatatgaaagcagagatactaccagacacgta
atcttcactgcagagacgcacaacttccctaccggtgttgctccattcagcggagccaca
actggaactggcgggcgaatcagagatgtgcagagtgctggaaagggtggtcatgtgatt
gcaggcactgctggctactgctttggtaacctgcacattccaggttttgtgctcccatgg
gaggaggaaggctgggaatacccatcaagctttgctcctccacttcaggtggccattgag
gccagtgacggagcctctgactatggcaataagtttggggagccagttctcgcaggcttt
gctcgttcctttggaatgcggttggctaatggtgaacggcgggagtggattaagccaatc
atgttcagcggtgggttgggatctattgaggatccacatgtgaggaaagatcaagctgag
ccaggtatggaagtggtgaaaattggaggtcctgtgtacaggattggtgttggtggaggt
gctgcttcttctgtacaggttcaaggagataactccagtgccagagaccttggagcagtt
caaagaggagatgctgaaatggagcaaaagatgaaccgcgctctcagggcctgcctggag
cgtgtggaaggaaacccaatctgcagcattcatgatcagggtgctggtggcaatggtaac
gtgttaaaggaactaagtgaacctgctggtgccgttatctacactgaaaagtttaagaga
ggagaccccaccctcagtgttttggagctttggggggcggagtatcaggagagtaatgct
ctgttgctccgcccctctgaccggagcttcctagagagggtctgtcagagggaaaagtgt
cctgtcgactttgtgggcaagataactggtgatggcaagatcgtgctggttgatggcttg
cgtaaacagaatgatgtacttgaaggtgcacgaaaccctgtggatctggagctggactgg
gtcctaggaaagatgccacaaaaggagttcatattggagcacaggtctgtttctctgcag
cctctcactcttcctgcaggtctttctgttcttccagctctggaaagagttctccggctg
cctgcagtggccagcaaacgctacctaaccaataaggttgatcgatctgtgactggtctg
gtggctcagcagcagtgtgttggccctctccatactcctctggctgatgtggctgttgtt
gctctttctccgttcagcctccagggggcagccacagcgataggagagcagcccattaaa
ggcctgctctctccagcagctggagcccgaatggctgtaggagaagctctcactaacttg
gtttttgcaagagtgtctgctctcaaggatgtaaagtgcagtggtaactggatgtgggct
gctaaactgccaggagagggagcttgtctgtgggacgcatgtcaggccatgtgtgaggtt
atgggtcagctgggagtggcagtggacggaggaaaagattcacttagcatggctgcacgc
gtcagtggagaaactgtcaaagctccaggctctcttgttatctcagtgtatgctgtgtgt
cctgatattacggccactgtgacccccgacctggacaaccctgaaggcaaaggtgtgctt
ctgtacgtgcctgtgagtgcaggtaaatacaggctgggcggctctgctttagctcagtgt
tttgggcagctgggagactgtagtccagatatggatcagccagacaagctctccgcttgc
ttcaacaccacacagacattgattcaggatcgactgctgactgctggacatgatgtcagt
gatgggggacttatttcttgtctgctggagatggcctttgcagggaattatgggatagaa
gtggacttgccgttagagggcgttgatgtgatggaggctctgttttcagaggagcttagt
cttgttctggaggtttgtgagcgtaatgcatccagtgtctgtcagagatacacagatgct
ggcctcttgtgtcacagaattggcacaacatctggttttggacccgatgccaaggtcaga
gtgagtctgtgtggacgggaagtgctgaacgagcgtttgcccacattaagggccatctgg
gaaagcactagttttgagctggagagactgcaggctaatccactgtgtgttcaagaggaa
gaacaaggacttgcttctcgcacacagccgtacctgaagctcacctttgacccctctcaa
acgccgatcattaaagagctcgctacagggaaagctcgtgttgctgttgtgagagaggaa
ggcagtaatggagacagagagatgtccgcttctctctttatggccggatttgaggtgtgg
gacgtcacaatgcaggacctgtgctccggctccacgacccttgaccctttccgagcagtg
gtgtttgtgggtggtttcagctatgcagatgtgttgggttcggctaaaggatgggctgcc
acagtgacctttaacaatagggctcgtgaggagtttgagcgtttccgcaagcgtgaggat
acactgagtttaggagtttgcaacggatgtcagctgctggctttactcggctgggtgggt
gaaagagaggatggaggttctgatgttactctgacccataacaagtctggtcggtttgaa
tcgaggtttgtgagtgtgggtatcctgccctctccagccatcatgctcaagggaatggaa
ggctctgctctgggtgtctgggtcgcacatggagaaggtctgatgcagtttcgttctcct
gaggctcaacagaagctaattggctcctctctggctcctctgcgttatgtggatgactcg
ggcaatccgactgaaatctatcccattaaccccaatggctctgcgcaaggtgttgcagga
atctgctcggcagatggacgccacctggccatgatgccccacccagagcgggcagtgctg
agttggcagtgggcttgggctcctcagcacctcaggggctcattggagccatcaccgtgg
cttagcatgttccgaaacgcagcagcctggtgccagaattcatag
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