Danio rerio (zebrafish): 793414
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Entry
793414 CDS
T01004
Symbol
top3b
Name
(RefSeq) DNA topoisomerase 3-beta-1 isoform X1
KO
K03165
DNA topoisomerase III [EC:
5.6.2.1
]
Organism
dre
Danio rerio (zebrafish)
Pathway
dre03440
Homologous recombination
dre03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
793414 (top3b)
03460 Fanconi anemia pathway
793414 (top3b)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
dre03032
]
793414 (top3b)
03400 DNA repair and recombination proteins [BR:
dre03400
]
793414 (top3b)
Enzymes [BR:
dre01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
793414 (top3b)
DNA replication proteins [BR:
dre03032
]
Eukaryotic type
DNA Topoisomerases
793414 (top3b)
DNA repair and recombination proteins [BR:
dre03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Bloom's syndrome complex (BTR)
793414 (top3b)
FA (Fanconi anemia) pathway
793414 (top3b)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_TOP3B
Toprim
Fer4_11
Motif
Other DBs
NCBI-GeneID:
793414
NCBI-ProteinID:
XP_003198651
ZFIN:
ZDB-GENE-070705-37
Ensembl:
ENSDARG00000027586
UniProt:
F1QNX4
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Position
5:complement(13212962..13251882)
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AA seq
861 aa
AA seq
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MRTVLMVAEKPSLAQSIAKILSKGSCSTRKGLNGACSVHEYMGSFTGQNVRFKMTSVCGH
VMSLDFIGKYNNWDKVDPAELFSKAPTEKKEANPKLNMVKFLQVEAKGCDYVVLWLDCDK
EGENICFEVLDAIQPVMNKPYGNERTVYRAKFSSITDTDICNAMNRLGEPNKNEALSVDA
RQELDLRIGCAFTRFQTKYFQGKYGNLDSSLISFGPCQTPTLGFCVERHDKIQSFKPEAY
WVVQAKVFKGKDSPLTLDWDRVRVFDRDIGQMFVNMAKTAKEARVDSVTKKEKAKQRPLA
LNTVEMLRVASSALGMGPQHTMQIAERLYTQGYISYPRTETTHYPENFDLKGTLKQQANS
TFWGETVKALLSEGINRPRKGADAGDHPPITPMRAASENELGSDGWRLYDYITRHFIATV
SPDCKYLQTTISFSIATEGFTCSGKTLISAGYTEVMPWQGIAQEEALPVCERGEMFTVDE
IKLLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRKLKPTNL
GIVLVHGYYKIDADLVLPTIRSAVEKQLTLIALGKANFQQVLQHTLDIFKRKFHYFVDSI
AGMDELMEVSFSPIAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYSLPQNGAIKL
YKELKCPLDEFELVLWTSGSRGKSYPVCPYCFSNPPFRDMKKGMGCNECTHPSCQHSLNS
LGIGQCVECETGVLVFDPTSGPKWRMACNKCNVVVHFFEQAHKVQVSQDSCDSCEASLVI
VDFNKTRSPLPDGETQHTGCVFCDSAFQDLVELKHATMRHPMHRAGGARRGRGKGRGRRP
MGRGNPKKPKDKMAALAAYFV
NT seq
2586 nt
NT seq
+upstream
nt +downstream
nt
atgaggactgtgttaatggtggctgagaagccctctctggctcagtccattgccaaaata
ctttctaaaggcagctgttcaacccgtaaaggcctgaatggagcctgctcggttcatgag
tacatgggaagcttcacgggacaaaatgtgaggtttaagatgacgtcagtgtgtggacac
gtcatgagtctggactttatcggaaagtataacaactgggataaagtcgatccagctgag
ctgtttagtaaagctccgactgaaaagaaggaagcaaaccccaaattaaacatggtcaaa
ttccttcaggttgaagcaaaaggatgtgattatgtcgttttgtggttggactgtgacaaa
gaaggagagaacatttgctttgaggtgttggatgccattcagcctgtaatgaataagcct
tatggtaacgagcgtacagtgtatcgggccaaattcagctccatcacagacactgatatc
tgtaacgccatgaaccgacttggagaacccaacaagaacgaggctctatctgtagatgct
cgtcaggaactggacctccggatcggttgtgctttcacacgtttccagactaaatacttc
caggggaaatatgggaatttggactcttccttgatctcatttggcccctgtcagactccc
acactgggcttttgtgtcgaaaggcatgacaagatccagtccttcaaacctgaagcttat
tgggtcgtacaagcaaaggtttttaaagggaaggacagtccgctcaccttggactgggac
cgtgtgcgagtttttgaccgagatattggtcagatgtttgttaacatggcaaagactgcc
aaggaggctagagttgactcggtgactaagaaagagaaagccaagcagagacctcttgca
ctgaacacagtggagatgttaagagtggccagctctgctttgggaatgggtccccagcat
accatgcagatagcggagcgtctctacacacagggttacatcagctaccctcgcacagag
accacacattatcctgaaaacttcgacctgaagggcaccctcaaacagcaggccaacagc
accttctggggtgaaacggtaaaagcactgctctctgagggaataaacaggcctaggaaa
ggagcagatgcaggagaccacccgccaatcactccaatgagagccgcttctgagaatgaa
ctgggcagtgatggctggcgtctgtatgattacatcacacggcacttcatagcgacggtg
agccccgactgcaaatacctgcagaccaccatttccttcagcatcgccacagagggcttc
acatgcagcgggaagacgctcatctctgctggttacacggaggtgatgccctggcagggt
attgcgcaggaggaggccttgccggtgtgtgagcgaggagaaatgtttactgtggacgag
attaaactgctggagaaacagaccaatcccccggattacctgactgaagccgaactcatc
acgctcatggagaagcatggcatcggcactgatgccagcatccccgtccacataaacaac
atctgccagaggaactatgtgacggttgaaagtggacgcaaactcaaacccaccaacctg
gggatagttctggttcacggttactataagattgatgcagatctggttctgcccacaatc
cgtagcgctgttgaaaagcagctgaccctgatagctttaggaaaagcaaactttcagcag
gtcttacagcacacactggacatcttcaagaggaagttccactactttgtggactcaatc
gcaggtatggatgagctgatggaggtgtccttctccccaatcgccgctactggaaaacct
ctttctcgctgcggcaagtgccatcgcttcatgaagtacatccaggctaaacccagtcgt
ctgcactgctctcactgtgacgagacctacagtttaccacagaacggagccattaagctc
tacaaagagctgaagtgtcctctggatgagtttgagctggttctctggacttcaggctct
cgtgggaaaagttatcctgtgtgtccgtactgcttcagcaaccctccgttcagagacatg
aagaaaggcatgggctgtaatgaatgcactcacccgtcctgtcagcactcgctcaactct
ctgggcattggtcagtgtgttgaatgtgagaccggcgtattggtgtttgatcccacctcg
ggcccaaagtggcgcatggcctgcaacaaatgcaacgtggtggtgcatttcttcgagcag
gcccataaagtgcaggtgtcccaggacagctgtgactcctgcgaagcctctctggtcatc
gtggactttaataagacgcgctcgccgctgcctgatggggagacacaacacactggctgc
gtgttctgcgattctgcatttcaggatctggtggagctgaaacacgccaccatgcgacac
cccatgcaccgggctgggggagcccgcagagggagagggaagggccgagggaggaggccc
atggggagaggaaatcccaaaaagcccaaagataaaatggcagccctggcagcgtatttc
gtatag
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