Danio rerio (zebrafish): 797132
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Entry
797132 CDS
T01004
Symbol
sirt1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
dre
Danio rerio (zebrafish)
Pathway
dre00760
Nicotinate and nicotinamide metabolism
dre01100
Metabolic pathways
dre04068
FoxO signaling pathway
dre04148
Efferocytosis
dre04218
Cellular senescence
dre04310
Wnt signaling pathway
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
797132 (sirt1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
797132 (sirt1)
04068 FoxO signaling pathway
797132 (sirt1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
797132 (sirt1)
09143 Cell growth and death
04218 Cellular senescence
797132 (sirt1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
dre03036
]
797132 (sirt1)
03029 Mitochondrial biogenesis [BR:
dre03029
]
797132 (sirt1)
Enzymes [BR:
dre01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
797132 (sirt1)
Chromosome and associated proteins [BR:
dre03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
797132 (sirt1)
Mitochondrial biogenesis [BR:
dre03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
797132 (sirt1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
797132
NCBI-ProteinID:
XP_001334440
ZFIN:
ZDB-GENE-070801-2
Ensembl:
ENSDARG00000068064
UniProt:
A0AA52K8U1
LinkDB
All DBs
Position
13:complement(54149929..54167615)
Genome browser
AA seq
742 aa
AA seq
DB search
MADGENKRAESAEPDEPLPKKPRLLELSGDSEHSATAGADTLDEKPARMDESQQALSINN
NNNTRPTEPGQPADPEPEISELTDEGVHSNGFTSPDLLRDDDDCSSRASSSDWTPQPQIG
SYRFIQQHIMRGTDPRAILKDLLPETVLPPDLDDMTLWQIIINISEPPKRKKRKDINTLE
DVVRLLNERKKILVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIDYFRR
DPRPFFKFAKEIYPGQFQPSPCHRFISMLDKKGRLLRNYTQNIDTLEQVAGIQKIIQCHG
SFATASCLICKHKVDCEAIREDIFNQVVPHCPRCPSDVPYAIMKPDIVFFGENLPEFFHR
AMKQDKDEVDLLIVIGSSLKVRPVALIPSSIPHDVPQVLINREPLPHLNFDVELLGDCDV
IVNELCHRLNGDFQQLCYNSSRLSEITEKPAAPEHTENTSADHSHADAEHIENTSADRDD
ADAEHIENTSADHSHADAEHIENTSADRDDADAEHIENTSADHSHADAEHIENTSADRDD
AEHTENTPTDHANAEHTEHTSAGHVNAEHIEHMSTDHANAKDDQSSLSVNEEELASPAAE
THALDSTEISAHTERSKEADAVNTDDAACVKDEENTDRLRVEMRRRCWRSRICQSPISKR
LGASQYLFQAPNRYVFHGAEVYSSSEDESSSSCSSESDGSFQHEDSEVEENGAAMTDKET
DTETVQDSEHRRLQTHCTQHTQ
NT seq
2229 nt
NT seq
+upstream
nt +downstream
nt
atggcggacggcgaaaataaacgggccgaatccgccgagccggacgagccgctaccgaag
aaaccaaggcttctggagctgtccggtgattcggagcacagcgcgaccgccggtgccgat
acattggacgagaaaccggcgcggatggacgagtcacagcaggccttatcgatcaacaac
aacaacaacactagaccgactgaacccgggcagccagccgacccggagcccgagatctcc
gagttaactgatgaaggtgttcattccaatggttttacatcccctgatcttcttcgggac
gatgatgactgctcatcccgtgccagctctagcgactggacgcctcagccacagattggg
tcctatcggttcattcagcagcacatcatgagaggaactgatcccagagccattctgaaa
gatttgcttcctgaaacggtgcttcctccagatctggatgacatgacgctgtggcagatc
atcatcaacatctctgagccgcccaaacgaaagaaacgcaaagacatcaacacgttagag
gacgtggtgcggctcctgaacgagaggaagaagattctggtgctcaccggtgctggggtg
tctgtttcctgtgggattcctgactttcgctctagagatggtatttatgctcgactcgct
gtagatttcccagaccttcctgatcctcaagccatgtttgacatcgactacttcaggaga
gatcccaggccttttttcaagtttgccaaggaaatctaccccggacagttccagccatct
ccatgtcaccgatttatatcaatgctggacaagaagggaaggttattgagaaactacacg
cagaatatcgacacactggagcaggtggctggaatacagaagatcattcagtgccacggg
tcttttgcgactgcctcctgtcttatctgtaagcataaggtggactgtgaagccataaga
gaagatatattcaaccaggttgttcctcattgtcccaggtgtccgtctgatgtcccgtac
gccatcatgaagccagacatcgtcttttttggagaaaaccttccagagtttttccacaga
gccatgaagcaggataaagatgaggtggacctcctcatcgtgatcggctcctcgctgaaa
gtgcggccagtggctcttatacccagctcgattcctcatgacgtgcctcaagtgctgatc
aaccgtgagccgctgccgcatctgaacttcgacgtggagctcctgggcgactgtgacgtg
atcgtgaacgaactctgccatcgcctgaacggagacttccagcagctctgctacaattca
tcacgtctcagcgagatcacagagaaaccggcagctcctgaacacacggagaacacgtct
gcagatcactctcatgctgatgctgaacatatagagaacacgtctgcagatcgcgatgat
gctgatgctgaacatatagagaacacgtctgcagatcactctcatgctgatgctgaacat
atcgagaacacgtctgcagatcgcgatgatgctgatgctgaacatatagagaacacgtct
gcagatcactctcatgccgatgctgaacatatcgagaacacgtctgcagatcgcgatgat
gctgaacatacagaaaatacacctacagatcacgctaatgctgaacatacagagcacaca
tctgcaggtcacgttaatgctgaacatatagagcacatgtctacagatcatgctaatgct
aaagacgatcagagctcactatcagttaatgaagaggaattagcgtctccagcagcagaa
acacacgcgctggactctacagagatttcagcacacacagagaggagtaaagaggccgat
gctgtgaacactgatgatgcagcgtgtgtaaaagatgaagaaaacacagatcgactgcgc
gtggaaatgcgcagacgctgctggaggagccgaatctgtcagagtccaatcagcaaacga
cttggagcgtcgcagtatttatttcaagcaccgaaccgttatgttttccacggggcggag
gtttactcgagctcagaggacgagagctccagttcgtgcagcagtgaaagcgacggatct
ttccagcatgaagacagcgaggtggaggaaaacggtgcagcaatgacggataaggaaacg
gacacagaaacagtacaggacagtgaacacagacgccttcagacacactgcacacaacac
acacaataa
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