Desmodus rotundus (common vampire bat): 112298036
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Entry
112298036 CDS
T05907
Symbol
ALK
Name
(RefSeq) ALK tyrosine kinase receptor
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro05200
Pathways in cancer
dro05223
Non-small cell lung cancer
dro05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112298036 (ALK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
112298036 (ALK)
09162 Cancer: specific types
05223 Non-small cell lung cancer
112298036 (ALK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dro01001
]
112298036 (ALK)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
dro04090
]
112298036 (ALK)
Enzymes [BR:
dro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
112298036 (ALK)
Protein kinases [BR:
dro01001
]
Receptor tyrosine kinases (RTK)
ALK family
112298036 (ALK)
CD molecules [BR:
dro04090
]
Proteins
112298036 (ALK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
MAM
Pkinase
ALK_LTK_GRD
Ldl_recept_a
FXa_inhibition
Motif
Other DBs
NCBI-GeneID:
112298036
NCBI-ProteinID:
XP_024408718
LinkDB
All DBs
Position
Unknown
AA seq
1621 aa
AA seq
DB search
MAAIGLLWLLPPLYSAAALGPGTETRTGTDQRVGSPAAGPALQPREPLSYSRLQRKSLAV
DFVVPSLFRVYARELLLPPPSPSQARDGRPEARGSLALDCAPLLRLVGPPPRVSWTGSTS
SPDPARALSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPEEAAAGLLQFNLSELFS
WWIRHGEGRLRIRLMPEKKASEVGREGKLSAAIRASQPRLFFQIFGTWGHSSLESPTNLS
SLPSDSFAWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHDLGNQSWSWRRVP
SEEASQMDLLDGPEAEHSKEMPRGSFLLLNTSANSKHTILSPWMRSSSEHCRLAVSVHRH
LQPSGRYAAQLLPHNEAGREILLVPTPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSL
SAVDFFALKNCSEGTPPGSKMALQSSFTCWNGTVLQLGQACDFHRDCAQGEDEGQLCSKL
PAGFYCNFEDGFCGWSQGLLSPHTPQWQVKTLKEAQFQDQQDHALLLNTTGVPTSASAAV
TSTTFPAPMKNSPCELRMAWLIHGALRGNVSLVLVENKTGNEQSRVIWHVAATEGLSLWQ
WTVLPLLDVADRFWLQIVAWWGQGSRATVAFDNISISLDCYLTISGEDKMLQNTAPKSRN
LFERNSNKEMKFWENTPREAPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYRNTNLSVVV
GSEGPLKGIQTWKVPATDTYSISGYGAAGGKGGRNTMMRSHGVSVLGIFNLEKGDTLYIL
VGQQGEDACPSTNQLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMKDGV
PVPLIIAAGGGGRAYGAKTDTFHPERLENNSSVLGLNGYSGAAGGGGGWNDNTSLLWSGK
SLLEGATGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEMDGED
GVSFISPLGVLYTPALKVMEGHGEVNIKHYLNCSHCEVDECHMDPDSHKVICFCEHGTVL
AEDGVSCIVSPTPEPHLPLSLVLSIVTSALVAALVLAFSGIMVVYRRKHQELQAMQMELQ
SPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLLRGLGHGAFGEVYEGQ
VSGMPSDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFI
LLELMAGGDLKSFLRETRPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARN
CLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWS
FGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRP
HFAIILERIEYCTQDPDVINTALPVEYGPLVEEEEKVPMRPKDPEGIPPLLVAPPPAKGE
DRQDPAAPPPPPSTSSGKAVKRPTAPEAPVGVPRGPAVGGGHVNMAFSQSNPPPELHKVQ
RSRNKPTSLWNPTYGSWFAEKPARKNEPPAKKDEPASGLPGRQGGRAVPPNTAAGAAPNA
ALLLEPSSLTARVKEVPLFRLRHFPCGNVNYGYQQQGLPLEAAAPATRHYGDTVLKSPPG
P
NT seq
4866 nt
NT seq
+upstream
nt +downstream
nt
atggcagccataggactcctatggctgctgccgcctctgtattcagcagcagccttgggc
cccgggactgagaccaggaccgggaccgaccagcgcgtgggctcgccggcagctgggccg
gcgctgcagccccgagagccgcttagctactcacgcctgcagaggaagagcctggcagtg
gactttgtggtgccctcgctcttccgtgtctacgctcgggagctgctgctgccgccgcct
tccccctcgcaggcaagggatggccggccggaggcgcgcggctcgctggctctggattgc
gccccactgcttaggctggtggggccaccaccgagagtctcctggacaggcagcaccagc
tcaccggacccggcgcgggcgctgtccagggttctgaagggcggctcagtccgcaagctc
cgaagggccaagcagctggtgctagagttgggagaggaggctatccttgagggctgcgtc
gggcccccagaggaggcggctgcagggctgctccagttcaaccttagtgagctgttcagc
tggtggattcgccacggcgagggtcggctgaggatccgcctgatgcctgagaagaaggcg
tcggaagtaggcagagagggaaagctgtcagcagcgatccgtgcctcccagccccgcctt
ttcttccagatctttgggacctggggtcacagctccttagagtcaccgacaaatctgtcc
tctcttccttctgattcttttgcatggaatttgacctggataatgaaagactccttccct
ttcctgtctcatcgcagccgatacggtctggagtgcagcttcgacttcccctgcgagcta
gagtactcccctccactgcatgaccttgggaaccagagctggtcctggcgccgtgtcccc
tccgaggaggcctcccagatggacctgttggacggacccgaggcagagcattccaaggag
atgcccagaggctccttcctcctcctgaacacctcagcgaactccaaacacaccatcctg
agcccgtggatgaggagcagcagcgagcactgcaggctggctgtctccgtgcacaggcac
ctgcagccttccgggaggtacgccgcccagctgctgccccacaacgaggctggaagagag
atcctcctggtacccactccggggaagcatggctggacagtgctgcagggaaggattggg
cgcccagagaacccgttccgagtggccctggagtacatctcaagtggaaaccggagcctg
tctgcagtggacttcttcgccctgaagaactgcagtgaaggaacacccccgggctccaag
atggccttacagagttccttcacttgctggaacgggacagtcctccagctcgggcaggcc
tgcgacttccaccgggactgcgcccagggagaagatgagggccagctatgcagtaaactc
cctgctggtttttactgcaatttcgaggatggcttctgtggctggtcccaaggcttgctc
tcgccccacacgccccagtggcaggtcaagaccctaaaggaggcccagttccaggaccag
caagaccacgccctgctgctcaacaccactggagtccccacttctgcgagcgctgcagtg
accagcacgacgtttcccgcaccgatgaagaactctccatgcgagctccgaatggcctgg
ctcatccatggggccttgaggggaaatgtctccttggtgctggtggagaacaaaaccggg
aatgagcaaagcagggtgatctggcacgttgccgccactgaaggcttgagcctgtggcag
tggacagtgctgcctctcctcgacgtcgctgacaggttctggctgcagattgtcgcttgg
tggggacaaggatccagagccaccgtggcttttgacaatatctccatcagcctggactgc
tacctcaccatcagtggggaggacaagatgctgcagaacacagcacccaaatcaagaaat
ctgtttgagagaaactcaaacaaggagatgaaattctgggaaaatacaccaagagaggcc
cccatctttgaccctacagttcactggctgttcaccacgtgcggggccagcgggccccat
ggccccacgcaggcccagtgcaacaacgcctaccggaacaccaacctgagcgtagtggtg
gggagcgagggcccactgaagggcatccagacctggaaggtgccagccaccgacacctac
agcatctcgggctacggagccgctggcgggaaaggcgggaggaacaccatgatgcggtcc
cacggtgtgtctgtgctgggcatcttcaacctggagaagggtgacacgctgtacatcctg
gtcgggcagcagggggaagacgcctgccctagcacaaaccaattaatccagaaagtctgc
attggagagaacaacgtgatcgaagaagaaatccgcgtgaacaggagcgtgcacgagtgg
gcaggagggggtggaggagggggcggagccacctacgtatttaagatgaaggacggcgtg
ccggtgcccctgatcattgcggctggcggtggtggcagggcctacggggccaagacagac
acgttccaccccgagagactggagaataactcctcagttctaggactcaacggctattcc
ggagccgcaggtggtggaggtggctggaatgataacacttccttgctctggtctggaaaa
tctttgctggagggtgccaccggaggacattcctgcccccaggccatgaagaagtggggg
tgggagaccagagggggtttcggagggggtggaggggggtgctcctcaggtggaggaggc
ggaggatatataggcggcaacgcagcctcaaacaatgaccctgagatggacggggaggac
ggggtgtccttcatcagtcccctgggcgtcctgtataccccggctttgaaagtgatggaa
ggccacggggaggtgaatattaagcactacctgaactgcagccactgcgaggtagacgag
tgccacatggaccctgacagccacaaggtcatctgcttctgtgagcacgggacggtgctg
gctgaggacggtgtgtcttgcattgtgtcgcccaccccagagccccacctgccgctctcg
ctggtcctctccattgtgacctcggcactcgtggccgccctcgtcctggcgttctctggc
atcatggtcgtgtaccgccggaagcaccaggagctgcaagcaatgcagatggagctgcag
agccctgagtacaagctgagcaagctccgcacctcgaccatcatgacggactacaacccc
aactactgctttgccggcaagacctcctccatcagcgacctgaaggaggtacctcggaaa
aacatcaccctccttcggggtctgggccatggtgcgtttggggaggtgtatgaaggtcag
gtgtctggaatgcccagcgacccgagccccctgcaagtggctgtaaagacgctgcctgag
gtgtgctccgagcaggacgagctggacttcctcatggaggccctgatcatcagcaaattc
aatcaccagaacatcgtgcgctgtattggagtgagtcttcaagccctgccccggtttatc
ctgctggagctcatggcaggaggggacctcaagtcgttcctccgggagactcgccctcgc
ccgaaccagccctcctccctggccatgctggaccttctgcacgtggctcgggacattgcc
tgtggctgccagtacttagaggaaaaccacttcatccaccgggacattgctgccaggaac
tgcctcctaacctgtccaggccctggaagagtggccaagatcggagacttcgggatggcc
cgagacatctacagagccagctactaccggaaggggggctgtgccatgctgccggtgaag
tggatgccaccagaggccttcatggaaggaatatttacatctaaaacagacacgtggtcc
tttggagtgctgctgtgggaaatattctcccttggatacatgccataccctagcaaaagc
aaccaggaagttctggagttcgtcaccagcggaggacggatggacccccctaagaactgc
cctgggcctgtatacaggataatgacccagtgctggcaacatcagcccgaagacaggccc
cacttcgccatcattttggagaggatcgaatactgcactcaggatccagacgtgatcaac
accgccctgcccgtggaatatggcccactcgtggaagaggaggagaaagtgcccatgagg
cccaaagaccccgagggaatccctcctctcctcgtggctcccccaccagctaaaggggag
gaccggcaggaccccgccgccccgccgcctccgccttccacgtcctccggcaaagccgtg
aagaggcccacagccccggaggcccccgttggagtccctcgggggccggctgtgggaggg
ggccacgttaacatggcattctcgcagtccaacccgccgccggagctgcacaaagtgcag
agatccaggaacaagccaaccagcctgtggaacccaacctacggctcgtggttcgcagag
aaacctgcgaggaagaacgagcctcccgcaaagaaggacgagcccgcgagcgggctcccg
gggcggcagggcggccgtgcggtgcccccgaacactgcggccggcgcggcccccaatgct
gccctgctgctggagccctcctcgctgaccgcgcgcgtgaaggaggtgcccctgttcagg
ctgcgccacttcccgtgtgggaacgtcaactacggctaccagcagcagggcttgcccctg
gaggccgccgcccccgcgacccggcactacggggacacggttctgaaaagcccacccggg
ccctga
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