Desmodus rotundus (common vampire bat): 112298867
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Entry
112298867 CDS
T05907
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro01524
Platinum drug resistance
dro03440
Homologous recombination
dro03460
Fanconi anemia pathway
dro04120
Ubiquitin mediated proteolysis
dro04151
PI3K-Akt signaling pathway
dro05206
MicroRNAs in cancer
dro05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
112298867 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
112298867 (BRCA1)
03460 Fanconi anemia pathway
112298867 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
112298867 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
112298867 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
112298867 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
112298867 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
dro01009
]
112298867 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
dro04121
]
112298867 (BRCA1)
03036 Chromosome and associated proteins [BR:
dro03036
]
112298867 (BRCA1)
03400 DNA repair and recombination proteins [BR:
dro03400
]
112298867 (BRCA1)
Enzymes [BR:
dro01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
112298867 (BRCA1)
Protein phosphatases and associated proteins [BR:
dro01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
112298867 (BRCA1)
Ubiquitin system [BR:
dro04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
112298867 (BRCA1)
Multi subunit type E3
BRCC complex
112298867 (BRCA1)
Chromosome and associated proteins [BR:
dro03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
112298867 (BRCA1)
DNA repair and recombination proteins [BR:
dro03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
112298867 (BRCA1)
BRCA1-A complex
112298867 (BRCA1)
BRCA1-B complex
112298867 (BRCA1)
BRCA1-C complex
112298867 (BRCA1)
BRCA complex
112298867 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
112298867 (BRCA1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_3
zf-C3HC4_4
zf-RING_2
zf-RING_5
RING_XB3-XBAT31
BRCT_2
zf-RING_6
zf-Nse
zf-ANAPC11
zf-RING_10
zf-rbx1
Phage_T4_Y06P
Prok-RING_4
Baculo_IE-1
Motif
Other DBs
NCBI-GeneID:
112298867
NCBI-ProteinID:
XP_024409752
LinkDB
All DBs
Position
Unknown
AA seq
758 aa
AA seq
DB search
MDLCVDRVEEVQKVLSAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKSDITKRSLQESTRFSQLVEELLKVIHAFELDTGLQFANSYNFSKKGNNSPEHLKE
EVSIIQSLGYRNRALRLRQSEPENPTLQETSLGVPLSNLEVVRSLRTKQQVQPQNKSVYI
ELGSDSSEDTVNKASYYSVGDHGLLEITPQGDRAEARLSSAKKAAYEFSEDITTIEHCQS
SNKDLTTTEKKHAPEKLPEKYQDEAASEYESETVLSEDSSGPSSQNDILSTQQRDTMQDN
LIKIKQAMDQLEAVLEQQESQTSKKSPLLIADSCASKDLLTLERHTSGKVLMSEKSSECP
VSQNPENLSADKVQEYLGSSSSKSKETRVERSSSSKSQLLDDMGYVHSNSQSLQNRNCPS
QKELIKGIDMEEQQPTESEAQDLMEPSYLSRQDLEGTPALESGTRLFDDPESDPYEDRAP
EPAPVCSLPTSTSARTLPQFQVEESAQSPATAQTTNTAGHHVKGESVSGEKPEVVSSTKT
VNKRISMVASGLTQNELMLVHKFGRKHQITVTDLITEETTHVIMKTDADFVCERTLKYFL
GIAGGKWVVSYFWVTQSVKERKILDECDFEVRGDVINGRNHQGPKRARESQDRKIFRGLE
ICCYGPFINMPTDQLERMVRLCGAAVVKEPSAFTIGEGSHPVVVMQPDAWTEDSGSHVIG
QMCKAPVVTREWVLDSVALYQCQELDAYLVPKPAQSGC
NT seq
2277 nt
NT seq
+upstream
nt +downstream
nt
atggatttatgtgtggatcgcgttgaagaggtacaaaaggtcctcagtgctatgcagaaa
atcttagagtgtccaatctgtctggagttaatcaaagagcctgtttctacaaaatgtgac
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccgtcacag
tgtcctttgtgtaagagcgatataaccaaaagaagcctacaagaaagtacaagatttagt
caacttgttgaagagctattgaaagtcattcatgcctttgagctggacacaggattgcag
tttgcaaatagttataacttttcgaaaaagggaaataactctcctgagcatctaaaggag
gaagtttctatcatccagagtttgggttaccgaaaccgtgccctaagacttcgacaaagt
gaacctgagaaccctaccttgcaggaaaccagtcttggtgtcccactctctaaccttgaa
gttgtgagatcgctgaggacaaagcagcaggtacaacctcagaataagtctgtctacatt
gaattgggatccgattcttctgaagatacagttaataaggcaagttattacagcgtggga
gatcacggtctgttagagatcactcctcaaggagacagggctgaagcccgcttgagttct
gcaaaaaaggctgcttatgagttttctgaggatataacaactattgaacattgtcagtcc
agtaataaagatttgaccaccactgagaagaagcatgcacctgagaagcttccagaaaag
tatcaggatgaagcagcatctgagtacgagagtgaaacagtcctctctgaagactcttca
gggccgtcctctcagaacgatattttatccactcagcagagagacaccatgcaggataac
ctgataaaaatcaagcaggcgatggaccagctagaggctgtgttagagcagcaggagagc
cagacttccaaaaagtcccccctcctcatcgccgattcttgtgcctccaaggacctgctg
actctggagcgacatacatcaggaaaagtattaatgtcagagaaaagtagtgaatgtcct
gtgagtcagaatccggaaaacctttctgcagacaaggttcaagagtatctgggtagttcc
tccagtaaaagtaaagaaacgagagtggaaaggtcttcctcttctaaatcccagttgttg
gatgacatggggtatgtgcatagcaactcacagagtcttcagaacagaaactgcccgtct
caaaaggagctcattaagggtattgatatggaggagcaacaaccaaccgagtctgaggcc
caagatttaatggagccgtcatatttgtcaagacaagatctcgagggaacccctgcccta
gaatctggaaccagactcttcgatgacccagagtctgatccctatgaagacagagccccc
gagccagctcctgtttgcagcctgccgacttcaacctctgcacggacgttaccccaattc
caagttgaagaatctgcccagagtccagctactgctcaaactactaacactgctgggcat
catgtgaagggagaaagtgtgagcggggagaagccagaagtggtatcttcaacaaaaaca
gtcaacaaaagaatatcaatggtggcgtcaggcttgacccaaaacgaattaatgctcgtg
cacaagtttggcagaaaacaccagatcactgtaactgatctgattactgaagagaccact
cacgtcattatgaaaacagatgctgattttgtctgtgaacggacactgaaatattttctg
ggaattgcaggaggaaaatgggtagttagctatttctgggtgacccagtctgttaaagaa
agaaagattctagatgagtgtgattttgaagtcagaggagacgttatcaatggaaggaac
caccaaggtccaaagcgagcaagagaatcccaggacagaaagatcttcaggggcctagaa
atctgttgctatgggccctttatcaacatgcccacagatcaactagagcggatggtgcgg
ctttgtggggctgccgtggtgaaggagccttcagcgttcaccatcggcgagggctctcac
ccagttgtggtcatgcagccggatgcctggacagaggacagtggctcccacgtgattggg
cagatgtgtaaggctcctgtggtgacccgagagtgggtattggacagcgtggccctctac
cagtgccaggagctggacgcctacctggtccccaagcctgcacagagcggctgctga
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integrated database retrieval system
