Desmodus rotundus (common vampire bat): 112302067 Help Entry 112302067         CDS       T05907                                  Symbol TNF Name (RefSeq) tumor necrosis factor isoform X1   KO K03156   tumor necrosis factor superfamily, member 2 Organism dro  Desmodus rotundus (common vampire bat) Pathway dro01523   Antifolate resistance dro04010   MAPK signaling pathway dro04060   Cytokine-cytokine receptor interaction dro04061   Viral protein interaction with cytokine and cytokine receptor dro04064   NF-kappa B signaling pathway dro04071   Sphingolipid signaling pathway dro04150   mTOR signaling pathway dro04210   Apoptosis dro04217   Necroptosis dro04350   TGF-beta signaling pathway dro04380   Osteoclast differentiation dro04612   Antigen processing and presentation dro04620   Toll-like receptor signaling pathway dro04621   NOD-like receptor signaling pathway dro04622   RIG-I-like receptor signaling pathway dro04625   C-type lectin receptor signaling pathway dro04640   Hematopoietic cell lineage dro04650   Natural killer cell mediated cytotoxicity dro04657   IL-17 signaling pathway dro04660   T cell receptor signaling pathway dro04664   Fc epsilon RI signaling pathway dro04668   TNF signaling pathway dro04920   Adipocytokine signaling pathway dro04930   Type II diabetes mellitus dro04931   Insulin resistance dro04932   Non-alcoholic fatty liver disease dro04933   AGE-RAGE signaling pathway in diabetic complications dro04936   Alcoholic liver disease dro04940   Type I diabetes mellitus dro05010   Alzheimer disease dro05014   Amyotrophic lateral sclerosis dro05020   Prion disease dro05022   Pathways of neurodegeneration - multiple diseases dro05132   Salmonella infection dro05133   Pertussis dro05134   Legionellosis dro05135   Yersinia infection dro05140   Leishmaniasis dro05142   Chagas disease dro05143   African trypanosomiasis dro05144   Malaria dro05145   Toxoplasmosis dro05146   Amoebiasis dro05152   Tuberculosis dro05160   Hepatitis C dro05161   Hepatitis B dro05163   Human cytomegalovirus infection dro05164   Influenza A dro05165   Human papillomavirus infection dro05166   Human T-cell leukemia virus 1 infection dro05168   Herpes simplex virus 1 infection dro05169   Epstein-Barr virus infection dro05170   Human immunodeficiency virus 1 infection dro05171   Coronavirus disease - COVID-19 dro05205   Proteoglycans in cancer dro05310   Asthma dro05321   Inflammatory bowel disease dro05322   Systemic lupus erythematosus dro05323   Rheumatoid arthritis dro05330   Allograft rejection dro05332   Graft-versus-host disease dro05410   Hypertrophic cardiomyopathy dro05414   Dilated cardiomyopathy dro05417   Lipid and atherosclerosis dro05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:dro00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     112302067 (TNF)    04350 TGF-beta signaling pathway     112302067 (TNF)    04064 NF-kappa B signaling pathway     112302067 (TNF)    04668 TNF signaling pathway     112302067 (TNF)    04071 Sphingolipid signaling pathway     112302067 (TNF)    04150 mTOR signaling pathway     112302067 (TNF)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     112302067 (TNF)    04061 Viral protein interaction with cytokine and cytokine receptor     112302067 (TNF)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     112302067 (TNF)    04217 Necroptosis     112302067 (TNF)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     112302067 (TNF)    04620 Toll-like receptor signaling pathway     112302067 (TNF)    04621 NOD-like receptor signaling pathway     112302067 (TNF)    04622 RIG-I-like receptor signaling pathway     112302067 (TNF)    04625 C-type lectin receptor signaling pathway     112302067 (TNF)    04650 Natural killer cell mediated cytotoxicity     112302067 (TNF)    04612 Antigen processing and presentation     112302067 (TNF)    04660 T cell receptor signaling pathway     112302067 (TNF)    04657 IL-17 signaling pathway     112302067 (TNF)    04664 Fc epsilon RI signaling pathway     112302067 (TNF)   09152 Endocrine system    04920 Adipocytokine signaling pathway     112302067 (TNF)   09158 Development and regeneration    04380 Osteoclast differentiation     112302067 (TNF)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     112302067 (TNF)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     112302067 (TNF)    05170 Human immunodeficiency virus 1 infection     112302067 (TNF)    05161 Hepatitis B     112302067 (TNF)    05160 Hepatitis C     112302067 (TNF)    05171 Coronavirus disease - COVID-19     112302067 (TNF)    05164 Influenza A     112302067 (TNF)    05168 Herpes simplex virus 1 infection     112302067 (TNF)    05163 Human cytomegalovirus infection     112302067 (TNF)    05169 Epstein-Barr virus infection     112302067 (TNF)    05165 Human papillomavirus infection     112302067 (TNF)   09171 Infectious disease: bacterial    05132 Salmonella infection     112302067 (TNF)    05135 Yersinia infection     112302067 (TNF)    05133 Pertussis     112302067 (TNF)    05134 Legionellosis     112302067 (TNF)    05152 Tuberculosis     112302067 (TNF)   09174 Infectious disease: parasitic    05146 Amoebiasis     112302067 (TNF)    05144 Malaria     112302067 (TNF)    05145 Toxoplasmosis     112302067 (TNF)    05140 Leishmaniasis     112302067 (TNF)    05142 Chagas disease     112302067 (TNF)    05143 African trypanosomiasis     112302067 (TNF)   09163 Immune disease    05310 Asthma     112302067 (TNF)    05322 Systemic lupus erythematosus     112302067 (TNF)    05323 Rheumatoid arthritis     112302067 (TNF)    05321 Inflammatory bowel disease     112302067 (TNF)    05330 Allograft rejection     112302067 (TNF)    05332 Graft-versus-host disease     112302067 (TNF)   09164 Neurodegenerative disease    05010 Alzheimer disease     112302067 (TNF)    05014 Amyotrophic lateral sclerosis     112302067 (TNF)    05020 Prion disease     112302067 (TNF)    05022 Pathways of neurodegeneration - multiple diseases     112302067 (TNF)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     112302067 (TNF)    05418 Fluid shear stress and atherosclerosis     112302067 (TNF)    05410 Hypertrophic cardiomyopathy     112302067 (TNF)    05414 Dilated cardiomyopathy     112302067 (TNF)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     112302067 (TNF)    04940 Type I diabetes mellitus     112302067 (TNF)    04936 Alcoholic liver disease     112302067 (TNF)    04932 Non-alcoholic fatty liver disease     112302067 (TNF)    04931 Insulin resistance     112302067 (TNF)    04933 AGE-RAGE signaling pathway in diabetic complications     112302067 (TNF)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     112302067 (TNF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:dro04052]     112302067 (TNF)    00536 Glycosaminoglycan binding proteins [BR:dro00536]     112302067 (TNF) Cytokines and neuropeptides [BR:dro04052]  Cytokines   Tumor necrosis fators    112302067 (TNF) Glycosaminoglycan binding proteins [BR:dro00536]  Heparan sulfate / Heparin   Cytokines    112302067 (TNF) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TNF Motif Other DBs NCBI-GeneID:  112302067 NCBI-ProteinID:  XP_024413369 LinkDB All DBs Position Unknown AA seq 230 aa AA seqDB search MSTESMIRDVELAETVLPKKAGGLQGSRRCLCLSLFSFLLVAGATTLFCLLHFGVIGPQR EEQFLIGPSLAQTLGLSSRTPSDKPVAHVVANQQTVGKLQWKSQVANALLANGVRLTDNQ LVVPSDGLYLIYSQVLFKGQGCPPTHLLLTHTISRFAVSYPRKVSLLSAIKSPCQRETPE GTEAKPWYEPIYLGGVFQLEKGDQLSAEINLPDYLDFAESGQVYFGIIAL NT seq 693 nt NT seq  +upstreamnt  +downstreamnt atgagcactgagagcatgatccgggacgtggagctggctgagacggtgctccccaagaag gcagggggtctccagggctccagacggtgcttgtgcctcagcctcttctccttcctcctt gtggcaggagccaccacactcttctgcctgttgcacttcggggtgatcggcccccagagg gaagagcagttcctaattggcccctcactggcccagacccttggattatcttctcgaacc ccaagtgacaagcctgttgcccatgttgtagcaaaccagcaaactgtggggaagctgcag tggaagagccaggttgccaacgctctcctggccaatggcgtgcgactgacagacaaccag ttggttgtgccctcggacgggctgtacctcatctactcccaggtcctcttcaagggccaa ggctgccctccaacccacttgctcctcacccacaccatcagccgctttgctgtctcttac ccccgaaaggtcagcctcctctctgccatcaagagcccttgccagagggagaccccagag gggactgaggccaagccctggtatgaacccatctacctgggaggggtcttccagctggag aaaggggatcaactcagcgccgagatcaacctgcccgactatctcgattttgccgaatcc gggcaggtctactttgggatcattgccctgtga

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