Desmodus rotundus (common vampire bat): 112309331
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Entry
112309331 CDS
T05907
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro04010
MAPK signaling pathway
dro04020
Calcium signaling pathway
dro04022
cGMP-PKG signaling pathway
dro04024
cAMP signaling pathway
dro04260
Cardiac muscle contraction
dro04261
Adrenergic signaling in cardiomyocytes
dro04270
Vascular smooth muscle contraction
dro04713
Circadian entrainment
dro04720
Long-term potentiation
dro04723
Retrograde endocannabinoid signaling
dro04724
Glutamatergic synapse
dro04725
Cholinergic synapse
dro04726
Serotonergic synapse
dro04727
GABAergic synapse
dro04728
Dopaminergic synapse
dro04742
Taste transduction
dro04911
Insulin secretion
dro04912
GnRH signaling pathway
dro04921
Oxytocin signaling pathway
dro04924
Renin secretion
dro04925
Aldosterone synthesis and secretion
dro04927
Cortisol synthesis and secretion
dro04929
GnRH secretion
dro04930
Type II diabetes mellitus
dro04934
Cushing syndrome
dro04935
Growth hormone synthesis, secretion and action
dro05010
Alzheimer disease
dro05020
Prion disease
dro05022
Pathways of neurodegeneration - multiple diseases
dro05031
Amphetamine addiction
dro05207
Chemical carcinogenesis - receptor activation
dro05410
Hypertrophic cardiomyopathy
dro05412
Arrhythmogenic right ventricular cardiomyopathy
dro05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112309331 (CACNA1C)
04020 Calcium signaling pathway
112309331 (CACNA1C)
04024 cAMP signaling pathway
112309331 (CACNA1C)
04022 cGMP-PKG signaling pathway
112309331 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
112309331 (CACNA1C)
04929 GnRH secretion
112309331 (CACNA1C)
04912 GnRH signaling pathway
112309331 (CACNA1C)
04921 Oxytocin signaling pathway
112309331 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
112309331 (CACNA1C)
04924 Renin secretion
112309331 (CACNA1C)
04925 Aldosterone synthesis and secretion
112309331 (CACNA1C)
04927 Cortisol synthesis and secretion
112309331 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
112309331 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
112309331 (CACNA1C)
04270 Vascular smooth muscle contraction
112309331 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
112309331 (CACNA1C)
04727 GABAergic synapse
112309331 (CACNA1C)
04725 Cholinergic synapse
112309331 (CACNA1C)
04728 Dopaminergic synapse
112309331 (CACNA1C)
04726 Serotonergic synapse
112309331 (CACNA1C)
04720 Long-term potentiation
112309331 (CACNA1C)
04723 Retrograde endocannabinoid signaling
112309331 (CACNA1C)
09157 Sensory system
04742 Taste transduction
112309331 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
112309331 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
112309331 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
112309331 (CACNA1C)
05020 Prion disease
112309331 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
112309331 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
112309331 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
112309331 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
112309331 (CACNA1C)
05414 Dilated cardiomyopathy
112309331 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
112309331 (CACNA1C)
04934 Cushing syndrome
112309331 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
dro04040
]
112309331 (CACNA1C)
Ion channels [BR:
dro04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
112309331 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
112309331
NCBI-ProteinID:
XP_024421338
LinkDB
All DBs
Position
Unknown
AA seq
2168 aa
AA seq
DB search
MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLVPEHIPTPGAALSWQAAIDAAR
QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
VEWKYPLPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLK
VIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKT
CYNQEGIADAPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPRHGITNFDNFAFAMLTVF
QCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKA
RGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNRGAPAGLLDQKKGK
FAWFSHSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRF
CRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEML
LKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKVMSPLGISVLRCVRLLRIFKITR
YWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNF
PQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIA
VDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEETKEEKIELKSITAD
GESPPTTKINMDNLQPNENEDKSVYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAV
PMPEASAFFIFSPNNRFRLQCHRIVNDSIFTNLILFFILLSSISLAAEDPVQHTSFRNHI
LFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAIN
VVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFK
GKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVS
TFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQ
GEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLN
TICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVV
GSIVDIAITEVNPAEHTQCSPFMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI
WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ
AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS
DGRSAFPQTFTTQRPLHINKTGNSPGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN
TALGRFPRPTGYPSVVSTVEGHGPPLSPAIRVQEASWKLSSKRCHSRESQIAMVCPEEFS
QEETYEAKVREDTEYCSEPSLASTERLAYQDDENRQLTLPEEDKRDTRQSPKRGFLRSAS
LGRRASFHLECLKRQKNQGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPC
ATPPATPGSRGWLPQPIPTLRLEGTESSEKLNSSFPSIHCGSWSGEPMPCGENSSTTRRA
RPVSLTVPSQAGAWGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTI
EEMESAADNILSGGTQQSPNGTLLPFVNCRDRGQDRAGGEEDGPCGPSQECRKSEEELQD
SRAYVSSL
NT seq
6507 nt
NT seq
+upstream
nt +downstream
nt
atggttaatgaaaacacgaggatgtacatcccagaggaaaaccaccaaggttccaactat
gggagcccacgcccagctcatgccaacatgaatgccaatgcagcagcagggcttgtcccc
gagcacatccccaccccaggggcagccctgtcctggcaggcagccattgatgcggcccgg
caggccaagctgatgggaagtgctggcaatgccaccatctccacggtcagctccacacag
cggaagcggcagcagtatgggaaacccaagaagcagggcagcaccactgccacacgcccg
cctcgtgccctgctctgcctcactctaaagaaccccatccggagggcatgcatcagcatt
gtcgaatggaaatatcctttaccatttgaaatcattattttactgactatttttgccaat
tgtgtggccttagcgatctatattccctttccagaagatgactccaacgccaccaattcc
aacctggaacgagtggaatatctctttctcatcatttttactgtggaagcatttttaaaa
gtaatagcctatggacttctctttcaccctaatgcttacctccgcaatggttggaattta
ctagattttataattgtggttgtagggctttttagtgcaattttagaacaagcaaccaaa
gctgacggggcaaatgctctaggagggaaaggggctggatttgatgtgaaggcgctgagg
gcattccgcgtgctgcgccccttgcggctggtgtctggagtcccgagtctccaggtggtt
ctgaattccatcatcaaggccatggtccccctgctgcatattgccctgctagtgctgttt
gtcatcatcatctatgctatcattggcctggagctcttcatggggaagatgcataagacc
tgctacaaccaggaaggcatagcagatgctccagcagaagacgacccctccccttgtgct
ctggagacaggccacggacggcagtgtcagaacggcaccgtgtgcaagcccgggtgggac
gggcccaggcacggcatcaccaactttgacaacttcgccttcgccatgctgacagtgttc
cagtgcatcaccatggagggctggacagatgtgctgtactgggtcaatgatgccgtagga
agggactggccctggatctattttgttacactaatcatcatagggtcattttttgtactt
aacttggttctcggtgtccttagcggagagttctccaaagagagggagaaggccaaggct
cgaggagatttccagaagctgcgagagaagcagcagctggaagaggacctgaaaggctac
ctggactggatcacacaggcggaagacattgaccccgagaatgaggatgaaggcatggat
gaggaaaagccccgaaacagaggagctccagcaggcttgcttgatcagaagaaagggaag
tttgcttggtttagtcactccacagaaacccatgtgagcatgcccacaagtgagacggag
tctgtcaacactgagaacgtggctggcggtgacatcgaaggagaaaactgtggggccagg
ctggcccaccggatctccaagtcgaagttcagtcgctactggcgtcggtggaatcggttc
tgcagaagaaagtgtcgtgccgcggtcaagtccaatgtcttctactggctcgtgatcttc
ctcgtgttcctcaacacgctcaccattgcctcagaacattacaaccagccccactggctc
acagaagtgcaagacacagccaacaaggccctcctggcccttttcaccgcggagatgctg
ctgaagatgtacagcctgggcctgcaggcctacttcgtgtcgctcttcaaccgctttgac
tgcttcattgtgtgcgggggcatcctggagaccatcctggtggagaccaaggtcatgtct
cccttgggcatctctgtgctcagatgtgttcggcttctgcggatattcaaaatcaccagg
tactggaactccttaagcaacctggtggcatccttgctgaactccgtgcgctccatcgcc
tccctcctgctcctcctcttcctcttcatcatcatcttctccctgctggggatgcagctc
tttggaggaaagttcaactttgatgagatgcagacccgaaggagcacatttgataacttt
ccccagtccctcctcactgtgtttcagatcctgaccggggaggactggaattcggtgatg
tatgatgggatcatggcttatggcggcccctcttttccagggatgttagtctgtatttac
ttcatcatcctcttcatctgtggaaactatatcctactgaatgtattcttggccattgct
gtggacaacctggctgatgccgagagcctcacatctgcccaaaaagaggaagaagaagag
aaggaaagaaagaagctggccaggactgccagcccagagaagaaacaggaggtgatggag
aagccagcagtggaggagaccaaggaggagaaaattgagctgaaatccatcacagctgat
ggagagtcccctcccaccaccaagatcaacatggacaacctccagcccaatgaaaatgaa
gataaaagtgtctaccccaacccagaaactacaggagaagaggatgaggaggagcctgag
atgcccgtgggcccacgcccacgcccactctctgagctgcacctcaaggaaaaggcagtg
cccatgcctgaagccagtgcatttttcatctttagtcccaacaacaggtttcgcctccaa
tgccaccgtatcgtcaatgactcaatcttcaccaacctgatcctcttcttcattctgctc
agcagcatttccctggctgctgaggaccctgtccagcacacctccttccggaaccatatt
ctgttttattttgatattgtttttactaccattttcaccattgaaattgctctgaagatg
actgcttacggggctttcttgcacaagggctccttctgcaggaactacttcaacatcttg
gacctgctagtggtcagcgtgtccctcatctcctttggcatccagtccagtgcaatcaat
gttgtaaagatcttgcgagttctgcgagtcctcaggcccttgagagctatcaacagagcc
aagggactaaagcacgtggttcagtgcgtgttcgtcgccatccggaccatcgggaacatc
gtgatcgtcaccacgctgcttcagttcatgttcgcctgcattggggtgcagctcttcaag
ggaaagctgtacacctgttcagatagctccaagcagacggaggcagaatgcaagggtaac
tacatcacatacaaggatggggaggttgaccaccccatcatccagccccgcagctgggag
aacagcaagtttgactttgacaatgttctggcagccatgatggctctcttcactgtctcc
acctttgaggggtggccggagctgctgtaccgctccatcgactcccacacagaagacaag
ggccccatctacaactaccgagtagagatctccatcttcttcatcatctacatcatcatc
gtcgctttcttcatgatgaacatcttcgtgggtttcgtcatcgtcaccttccaggagcag
ggagagcaggagtacaagaactgtgagctggacaagaaccagcgacagtgtgtggaatat
gccctcaaagcccggcccctgcggaggtacatacccaagaaccagcaccagtacaaagtg
tggtacgtggtcaactccacctactttgagtacctgatgtttgtcctcatcctgctcaac
accatctgcttggccatgcagcactacggtcagagctgcctgtttaaaattgccatgaac
atcctcaacatgctcttcactggcctcttcactgtggagatgattctgaagctcattgcc
tttaaacccaagcactatttctgtgatgcatggaatacgtttgacgccttgattgttgtg
ggtagcattgttgatatagcaatcaccgaggtaaacccagctgaacatacccaatgctct
ccctttatgaacgcagaggagaactcccgcatctccatcaccttcttccgcctcttccgg
gtcatgcgcctggtcaagctgctgagccgtggagagggcatccggaccctgctgtggacc
ttcatcaagtccttccaggccctgccctacgtggctctgctgatagtgatgctgttcttc
atctatgctgtgatcggaatgcaggtatttgggaaaattgccctgaatgacaccacagag
atcaaccgcaacaacaactttcagaccttcccccaagctgtgctgcttctcttcaggtgt
gccactggggaggcgtggcaggacatcatgctggcctgcatgccagggaagaagtgtgcc
ccagagtctgagcccagcaacagcacggaaggagagacgccctgtggcagcagcttcgct
gtcttctacttcatcagcttctacatgctctgtgccttcctgatcatcaacctctttgta
gctgtcatcatggacaactttgactacctgacaagggactggtccatccttggtccccac
catctggacgaatttaaaagaatctgggcagagtatgacccagaagccaagggtcgtatc
aaacacctggatgtggtgaccctgcttcggcggattcagcccccactgggttttgggaag
ctgtgccctcaccgtgtggcttgcaaacgtctggtctccatgaacatgcctctgaacagt
gatgggacggtcatgttcaatgccaccctgtttgccctggtccggacagctctgagaatc
aaaacagaagggaacctggaacaagccaatgaggagttgcgggccatcatcaagaagatc
tggaagcggaccagcatgaagctgctggaccaagtggtgcctcccgcaggagatgatgaa
gtcacggttggcaagttttatgctactttcttgatccaagagtacttccggaaattcaag
aagcgcaaagagcaaggcctcgtgggcaagccctcccagaggaacgccttgtcgctgcag
gctggcttgcgcacgctgcacgacattggccctgagatccgcagggccatctcgggagac
ctgacggctgaggaggagctggacaaggccatgaaggaggctgtgtctgctgcctctgag
gatgacatcttcaggagagccggaggcctgtttggtaaccatgtcagctactaccaaagc
gatggccggagcgccttcccccagaccttcaccacccagcgcccgctgcatatcaacaag
acgggtaacagtcctggcgacaccgaatcaccgtcccacgaaaagctggtggactccact
ttcacccccagcagctactcctctactggctccaatgccaacatcaacaatgccaacaac
acagccctgggccgctttccccgccccaccggctaccccagcgtggtcagcactgtggag
ggccatggcccacccctgtctcctgctatccgggtgcaggaggcatcgtggaagctcagc
tccaagaggtgccactcccgggagagccagatagccatggtgtgtccggaggagttctct
caggaggagacctatgaggcaaaggtgcgcgaggacacggagtactgcagtgagcccagc
ctggcctccacggagaggctcgcctatcaggatgacgaaaaccgacaactgacactccca
gaggaggacaagagggacacccggcaatctccaaagaggggttttctccgctctgcctcc
ctaggtcggagggcctccttccacctagaatgtctgaagcgacagaagaatcaaggggga
gacatctctcagaagactgtcctgcccttgcatctggttcatcatcaggcactggcagtg
gcaggcctgagccccctcctccagagaagccattctcccaccacgttccccaggccatgt
gccacgccccctgccacgcccggcagccgaggctggctccctcagcccatccccacactt
cggctggaaggaaccgagtccagcgagaaactcaacagcagcttcccgtccatccactgt
ggctcctggtctggggagcccatgccctgtggggagaacagcagcaccacgcggagagcc
cggcctgtgtccctcactgtgcccagccaggccggggcctggggcaggcagttccatggc
agtgccagcagtctggtggaagcggtcttgatttcggaaggactggggcagtttgcccaa
gatcccaagtttatcgaggtcacgacccaggagctggccgacgcctgcgacatgaccata
gaggagatggagagcgctgctgacaacatcctcagtgggggcacccagcagagccccaac
ggcaccctattaccttttgttaactgcagggaccgggggcaggacagagcagggggcgaa
gaggacgggccctgtgggcccagccaggagtgtcggaagagtgaggaggagctgcaggac
agcagagcctacgtcagcagcctgtag
DBGET
integrated database retrieval system
