Desmodus rotundus (common vampire bat): 112321408 Help Entry 112321408         CDS       T05907                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism dro  Desmodus rotundus (common vampire bat) Pathway dro04022   cGMP-PKG signaling pathway dro04068   FoxO signaling pathway dro04081   Hormone signaling dro04140   Autophagy - animal dro04152   AMPK signaling pathway dro04211   Longevity regulating pathway dro04213   Longevity regulating pathway - multiple species dro04910   Insulin signaling pathway dro04920   Adipocytokine signaling pathway dro04923   Regulation of lipolysis in adipocytes dro04930   Type II diabetes mellitus dro04931   Insulin resistance dro04932   Non-alcoholic fatty liver disease dro04935   Growth hormone synthesis, secretion and action dro05010   Alzheimer disease dro05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:dro00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     112321408 (IRS2)    04022 cGMP-PKG signaling pathway     112321408 (IRS2)    04152 AMPK signaling pathway     112321408 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     112321408 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     112321408 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     112321408 (IRS2)    04923 Regulation of lipolysis in adipocytes     112321408 (IRS2)    04920 Adipocytokine signaling pathway     112321408 (IRS2)    04935 Growth hormone synthesis, secretion and action     112321408 (IRS2)   09149 Aging    04211 Longevity regulating pathway     112321408 (IRS2)    04213 Longevity regulating pathway - multiple species     112321408 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     112321408 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     112321408 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     112321408 (IRS2)    04932 Non-alcoholic fatty liver disease     112321408 (IRS2)    04931 Insulin resistance     112321408 (IRS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Mcp5_PH Motif Other DBs NCBI-GeneID:  112321408 NCBI-ProteinID:  XP_024434575 LinkDB All DBs Position Unknown AA seq 1405 aa AA seqDB search MVSPPLHSPPGPAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGGSGDEA TAGGGPAPQPPRLEYYESEKKWRSKAGAPKRVISLDCCLNINKRADAKHKYLIALYTKDE YFAVAAENEQEQEGWYRALTDLVSEGRAGAGDSTPSAVTAGSCSASLPGALGGSAGADDS YGLVAPATAAYRGVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLM NIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPR SKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPATKCSSCRVRT ASEGDGGAAAGTGAVGGRPVSVAGSPLSPGPVRVPLSRSHTLSXXXXXXASKVTLPPAGG ALQHSRSMSMPMAHSPPAATSPGSLSSSSGHGSGSYPLPPGPHTHLQHPLHHHTSQRPSS GSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGSELYGYMT MDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRAT FSGSSGRLCPSCPTSSPKVAYHPYPEDYGDIEIGSHRSSSSNLGTDDGYMPMTPGVALMG GGSGSCKSDDYMPMSPTSVSAPKQILQPRAAAAALPPTGPAVPAPANAAVRAFPENGASY KASSPAESSPEDSGYMRMWCGSKLSMENTDSKLLPNGDYLNMSPSDAGTLETPPDFFSAA LHGGEMLRGVPGYCYSSLPRSYKAPYTCNGDNDQYVLMSSPVGRILEEERQEPQASVATT QSASVLVAGVGGVGHTQPPHSVVPSPGRLGSSSSSRAEGFLNQRCRAVRPTRLSLEGLQT LPSMHEYPLPPEPKSPGEYINIDFGEAGARLSPPAPPLLASAASSSSLLSASSPASSLGS GTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGTQTGDPVASLDALLSPEASSRYPPLPPR PAAPSSLKSQPPPPPSPGELYRLPPASTSQGPSAASSSSSETGDNGDYTEMAFGVAATPP QPIVAPPKPEGARVTSPTSGMKRLSLMDQVSGVEAFLQAGQPPDPHRGAKVIRADPQGGR RRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGGSGVLGGGDEPLPSP HQLQPQLPQQARPWTPSQPGGLVGCPGGSGSPMRRETSAGFQNGLNYIAIDVRDEPGPSP SQQQHPQMHPQQHPHPQPGDKSTWGRTRSLGGLISTVGAGSAGGVCGGPGPGPLPSNTYA SIDFLSHHLKEATIVKDIHDLTRKAPFSSCAEEASWPPAAPSTHNASCSENLPLLDALPS TTAATVVGGGQSHLAGQLCVTNPSG NT seq 4218 nt NT seq  +upstreamnt  +downstreamnt atggtgagcccgccgctgcacagcccccctgggccggcgggcggcgacggccccaacctc aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaaacag aagcacggccacaagcgctttttcgtgctgcgcgggcccggcgggagcggcgatgaggcg acagcgggtgggggtccagcgccgcagccgccgcggctcgagtactacgagagcgagaag aagtggcggagcaaggcgggcgccccgaagcgggtcatctcactcgactgctgcctgaac atcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaaggacgag tacttcgctgtggcggccgagaacgagcaggagcaggaggggtggtaccgcgcgctcacc gacctggtcagtgagggccgcgctggtgccggcgactcgaccccctccgctgtcaccgcc gggtcctgcagtgcctctttgcccggcgccctgggtggctcggcgggtgctgatgacagc tacgggctggtggcgcccgccacggcagcctaccgaggggtatggcaggtgaacctgaag cccaagggtctgggccagagcaagaacctgacaggcgtctaccgcctgtgtctgtccgca cgcactatcggcttcgtaaagctgaactgtgagcagccgtcggtgacactgcagctcatg aacatccgccgctgcggccactcggacagcttcttcttcatcgaggtgggccgctcagct gtaaccggccctggcgagctgtggatgcaggccgacgactcggtggtggcccagaacatc catgagaccatcttggaggctatgaaagcgctcaaggagcttttcgagttccggccgcgc agcaagagccagtcctcgggctcctccgccacgcatcccattagtgtccccggcgctcgt cggcaccaccacctggtcaacctgccccccagccagactggcctggtgcgtcgctcgcgc accgacagcctagctgctaccccgccggctaccaaatgcagctcatgccgtgtgcgcacg gccagcgagggcgatggcggtgcggcggcgggaactggggcggtaggtggaaggcccgtg tcggtggctgggagtcccctgagcccggggccggtgcgcgtgcccctgagtcgctcacac accctgagcnnnnnnnnnnnnnnnnnngcgagcaaggtgacgctgccgccggcagggggc gccctgcaacatagccgctccatgtccatgcccatggcgcactcgcccccggcagccacc agcccaggcagcctttcgtccagcagcgggcatggctcgggttcctacccactgcctccg ggcccgcacacgcacctgcagcatcccctgcaccaccatacgagccagcggccctccagc ggcagcgcctcagcctctggctcccccagcgatcccggcttcatgtccttggatgagtat ggctccagccctggggatctgagagccttctgcagccacaggagcaacacacctgagtcc attgccgagacacccccggcaagggatggcagtgggagcgagctatatgggtacatgacc atggacaggcccctgagccactgtggccgcccctaccgtcgggtctcaggggatggagct caggacttggacagagggctgagaaagaggacttactccctgactacacctgctcggcag cggccagtgccccaaccctcctctgcatccttggatgaatacactctgatgcgggccacc ttctctggcagctcaggccgactctgcccgtcctgcccgacatcttctcccaaagtggcc taccacccttatcctgaagactatggcgacattgagattgggtcccataggagctctagc agtaacttgggcacagacgatggttacatgcccatgacccctggcgtggccctcatgggt ggtggcagtggcagctgcaagagcgacgactacatgcccatgagccccaccagcgtgtct gcccccaagcagatcctgcagccacgggctgctgctgcagccttgccccccaccggacct gcagtgccggcacccgccaatgcagcagtcagggcctttccagagaatggggccagctac aaagctagctccccggccgaaagctcccccgaggacagtggatacatgcgcatgtggtgt ggctccaagctgtccatggagaacaccgacagcaagctgcttcccaacggggactacctc aacatgtcccccagcgatgcaggcactttggagaccccacctgacttcttctcagcagcc ttgcatggcggagagatgctcaggggcgtccctggctactgttacagctctttgccccgc tcctacaaggctccctacacgtgcaatggggacaatgaccagtatgtgctcatgagctcc cccgtggggcgcatcctggaagaggagaggcaggagcctcaggccagtgtggcaaccaca cagtcggccagcgtcttggtggctggggtcggtggggttgggcacacccagccgcctcac tccgtggtgccttctccagggaggctaggtagcagcagcagtagccgcgcagagggcttc ctgaaccagcgttgccgggcagtgaggcccacgcgcctatccctggaggggcttcagacc ctacccagcatgcacgagtaccctttaccacccgagcccaagagtccgggcgagtatatc aatattgactttggggaggcgggagcacgcttgtcgccacctgcccctccgctgctggct tcggcagcctcgtcctcctctctgctgtctgctagcagcccagcctcttccctgggctca ggcaccccaggcactagcagcgacagccggcagcgctccccgctctctgactacatgaac cttgacttcagttctcccaagtcacctaagcctggtacccagactggtgacccggtggcc tccttggatgccctcctatctcccgaggcctcttcccggtacccgccattgcccccacgc cctgctgccccctcttccttgaagtcacagccacctcccccaccctccccaggagagttg taccgcctgcctcctgcatccacatcccagggccccagcgctgcctcctcttcgtcctca gagactggggacaatggtgactacaccgagatggcctttggcgtggctgccaccccgcca caacccatcgtcgccccccccaaaccagaaggtgcccgcgtgaccagccccacatctggc atgaagaggctgagtctcatggatcaggtgtctggagttgaggcctttctgcaggctggc cagcctccagacccacaccggggggccaaggtcatccgtgcagacccgcaggggggccgc cgccgccacagctctgagactttttcctcaaccaccactgtgactcccgtgtctccatcc tttgcccacaacccgaagcgccacaactcggcctctgtggaaaatgtctctctcaggaaa agcagcgaagggggtggcagcggtgtccttggtgggggcgatgagccccttccatccccc caccagttgcaaccacagctcccccagcaggctcggccatggacaccaagtcagcctggg ggcctggttggctgccctgggggcagtggctctccaatgcgcagggagacatctgctggc ttccagaatggcctcaactacattgccatcgatgtgagggacgagccagggccctcgccg tcccagcagcaacacccacaaatgcatccacagcagcatccacatccccagccaggcgac aagagcacctggggccggacccgtagccttgggggtctcatcagcactgtgggggctggc agtgctggtggggtgtgtggggggccaggccctggacccctgccctccaacacctatgcc agcatcgacttcttgtcccatcacctgaaggaggccaccattgtgaaagatatccatgac ctgaccaggaaagcccccttctcctcctgtgcagaggaggcctcctggccgccagcagcc ccctccactcataacgcctcctgttctgaaaacctgccgctgctagatgccctgccctcc accacagcggccactgtagttggaggtgggcagtcccatttggcggggcagctctgtgtt accaacccttcaggctga

DBGET integrated database retrieval system