KEGG   Dipodomys spectabilis (banner-tailed kangaroo rat): 122115583
Entry
122115583         CDS       T07891                                 
Symbol
Pak1
Name
(RefSeq) serine/threonine-protein kinase PAK 1
  KO
K04409  p21-activated kinase 1 [EC:2.7.11.1]
Organism
dsp  Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp04010  MAPK signaling pathway
dsp04012  ErbB signaling pathway
dsp04014  Ras signaling pathway
dsp04024  cAMP signaling pathway
dsp04062  Chemokine signaling pathway
dsp04360  Axon guidance
dsp04392  Hippo signaling pathway - multiple species
dsp04510  Focal adhesion
dsp04625  C-type lectin receptor signaling pathway
dsp04650  Natural killer cell mediated cytotoxicity
dsp04660  T cell receptor signaling pathway
dsp04666  Fc gamma R-mediated phagocytosis
dsp04810  Regulation of actin cytoskeleton
dsp05132  Salmonella infection
dsp05170  Human immunodeficiency virus 1 infection
dsp05205  Proteoglycans in cancer
dsp05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:dsp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122115583 (Pak1)
   04012 ErbB signaling pathway
    122115583 (Pak1)
   04014 Ras signaling pathway
    122115583 (Pak1)
   04392 Hippo signaling pathway - multiple species
    122115583 (Pak1)
   04024 cAMP signaling pathway
    122115583 (Pak1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    122115583 (Pak1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    122115583 (Pak1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    122115583 (Pak1)
   04650 Natural killer cell mediated cytotoxicity
    122115583 (Pak1)
   04660 T cell receptor signaling pathway
    122115583 (Pak1)
   04666 Fc gamma R-mediated phagocytosis
    122115583 (Pak1)
   04062 Chemokine signaling pathway
    122115583 (Pak1)
  09158 Development and regeneration
   04360 Axon guidance
    122115583 (Pak1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    122115583 (Pak1)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    122115583 (Pak1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    122115583 (Pak1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    122115583 (Pak1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dsp01001]
    122115583 (Pak1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dsp04131]
    122115583 (Pak1)
   03036 Chromosome and associated proteins [BR:dsp03036]
    122115583 (Pak1)
Enzymes [BR:dsp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     122115583 (Pak1)
Protein kinases [BR:dsp01001]
 Serine/threonine kinases: STE group
  STE20 family
   122115583 (Pak1)
Membrane trafficking [BR:dsp04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    122115583 (Pak1)
 Endocytosis
  Macropinocytosis
   Kinases
    122115583 (Pak1)
Chromosome and associated proteins [BR:dsp03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     122115583 (Pak1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT
Other DBs
NCBI-GeneID: 122115583
NCBI-ProteinID: XP_042544975
LinkDB
Position
Unknown
AA seq 544 aa
MSSNGLDTQDKPPAPPMRNTSTMIGAGGKDTATLNHGSKPLPPNPEEKKKKDRFYRSILP
GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN
PQAVLDVLEFYNSKKTTNSQKYMSFTDKSAEDYNSSNTLNVKTVSETPAVPPVSEDEDDD
DDATSPPVIAPRPEHTKSVYTRSVIEPLPITPTRDVATSPISPTENNTTPPDALTRNIEK
QKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQM
NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCM
DEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKR
STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGT
PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT
KNNH
NT seq 1635 nt   +upstreamnt  +downstreamnt
atgtcaagtaacggcctagatactcaggacaaacccccagcccctccgatgagaaacacc
agcactatgattggagctggcggcaaagacactgcaaccctaaaccatggttccaaacct
ctgcctccaaacccagaggagaagaaaaagaaggatcgattttaccgatccatcttacct
ggagataaaacaaataagaagaaggagaaggagcggccagagatttctcttccttcagat
tttgagcacacaattcatgtcggttttgatgctgtcacaggggagtttacaggcatgcca
gagcagtgggcccgcttgcttcaaacatcaaatatcactaaatcagagcaaaagaaaaac
ccacaggctgttctggatgtgttagaattttacaactctaagaagaccaccaacagtcag
aagtacatgagctttacagataagtcagccgaagattataattcttccaacactttgaat
gtgaagactgtgtctgagacccctgcggtgccaccagtttccgaagatgaagatgacgat
gatgatgctacttcccctccagtgattgctccacgcccggagcacacaaagtctgtatat
acaaggtctgtgattgaaccacttcctatcactccaactcgggatgtggctacatctccc
atttcacctactgagaataacaccactccaccagatgcgttgacccggaatattgagaag
cagaagaagaaacccaaaatgtctgatgaggagatcttagagaaattacggagcatagtg
agtgtgggcgatcctaagaagaagtatactcggtttgagaagattggacaaggtgcttca
ggaactgtgtacactgcgatggatgtagccacaggacaggaggtggccattaagcagatg
aatcttcagcagcagccgaagaaagagctgattattaatgagatcctggtcatgagggaa
aacaagaacccaaatattgtgaactacttggacagttaccttgtaggagatgagctatgg
gttgtcatggaatacttggctggaggctccttgacagatgtggtgacagaaacctgtatg
gatgaaggccagattgctgctgtgtgccgtgagtgtctgcaggccctagagttcctacat
tcaaaccaggtcattcacagagacatcaagagcgacaatattctgttgggaatggatggt
tctgtcaagttaaccgattttggattctgtgcacagataactccagaacagagcaaaagg
agcactatggtgggaactccatattggatggcacctgaggttgtaacgcggaaggcctat
ggacccaaggttgacatctggtccctgggcatcatggctattgaaatgattgaaggggag
cccccatacctcaatgaaaaccctctgagagccttgtacctcattgccaccaatgggact
ccagaacttcagaacccagagaagctgtctgctatcttccgggactttttaaaccgctgt
ctggagatggatgtagaaaagagaggatcagctaaagagctcctgcagcatcagttcctc
aagattgccaagcccctctccagcctcactccattgattgctgcagcaaaggaggcaacc
aagaacaatcactaa

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