Dipodomys spectabilis (banner-tailed kangaroo rat): 122125312
Help
Entry
122125312 CDS
T07891
Symbol
Ptk2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp01522
Endocrine resistance
dsp04012
ErbB signaling pathway
dsp04062
Chemokine signaling pathway
dsp04148
Efferocytosis
dsp04151
PI3K-Akt signaling pathway
dsp04360
Axon guidance
dsp04370
VEGF signaling pathway
dsp04510
Focal adhesion
dsp04670
Leukocyte transendothelial migration
dsp04810
Regulation of actin cytoskeleton
dsp04935
Growth hormone synthesis, secretion and action
dsp05100
Bacterial invasion of epithelial cells
dsp05135
Yersinia infection
dsp05146
Amoebiasis
dsp05163
Human cytomegalovirus infection
dsp05165
Human papillomavirus infection
dsp05170
Human immunodeficiency virus 1 infection
dsp05200
Pathways in cancer
dsp05202
Transcriptional misregulation in cancer
dsp05205
Proteoglycans in cancer
dsp05208
Chemical carcinogenesis - reactive oxygen species
dsp05222
Small cell lung cancer
dsp05417
Lipid and atherosclerosis
dsp05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
122125312 (Ptk2)
04370 VEGF signaling pathway
122125312 (Ptk2)
04151 PI3K-Akt signaling pathway
122125312 (Ptk2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
122125312 (Ptk2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
122125312 (Ptk2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
122125312 (Ptk2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
122125312 (Ptk2)
04062 Chemokine signaling pathway
122125312 (Ptk2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
122125312 (Ptk2)
09158 Development and regeneration
04360 Axon guidance
122125312 (Ptk2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122125312 (Ptk2)
05202 Transcriptional misregulation in cancer
122125312 (Ptk2)
05205 Proteoglycans in cancer
122125312 (Ptk2)
05208 Chemical carcinogenesis - reactive oxygen species
122125312 (Ptk2)
09162 Cancer: specific types
05222 Small cell lung cancer
122125312 (Ptk2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
122125312 (Ptk2)
05163 Human cytomegalovirus infection
122125312 (Ptk2)
05165 Human papillomavirus infection
122125312 (Ptk2)
09171 Infectious disease: bacterial
05135 Yersinia infection
122125312 (Ptk2)
05100 Bacterial invasion of epithelial cells
122125312 (Ptk2)
09174 Infectious disease: parasitic
05146 Amoebiasis
122125312 (Ptk2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122125312 (Ptk2)
05418 Fluid shear stress and atherosclerosis
122125312 (Ptk2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
122125312 (Ptk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dsp01001
]
122125312 (Ptk2)
01009 Protein phosphatases and associated proteins [BR:
dsp01009
]
122125312 (Ptk2)
Enzymes [BR:
dsp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
122125312 (Ptk2)
Protein kinases [BR:
dsp01001
]
Non-receptor tyrosine kinases
FAK family
122125312 (Ptk2)
Protein phosphatases and associated proteins [BR:
dsp01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
122125312 (Ptk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
122125312
NCBI-ProteinID:
XP_042555843
LinkDB
All DBs
Position
Unknown
AA seq
1099 aa
AA seq
DB search
MLLELAGQEALKPAGAICMEKSGCSPFPMCWAKEYDRYLASSKRMAAAYLDPNLNHTPSS
STKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRYDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGML
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL
GNSEKQGVRTHTVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDV
HQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVW
IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS
NDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEIL
MHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL
STILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHM
VQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTESWNHRPQEISMWQPNMEDSAVLDL
RGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPTG
NQHIYQPVGKPDPAAPPKKPPRPGAPSHLGSIASLSSPGDSYNEGVKPWRLQPQEISPPP
TANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIP
GLPASTHREIEMAQKLLNSDLGELIGKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKN
LLDVIDQARLKMLGQTRPH
NT seq
3300 nt
NT seq
+upstream
nt +downstream
nt
atgttgttggaactggcaggccaagaggccctgaaaccagcaggtgccatctgtatggag
aaaagcggctgtagtccatttccaatgtgttgggcaaaagaatatgacagatacctagca
tctagcaaaagaatggcagctgcttaccttgacccaaacttgaatcatacaccaagttca
agtactaagactcacctgggtactggtatggaacgttctcctggtgcgatggagcgagta
ttaaaggtctttcattattttgaaagcaatagtgagccaaccacctgggccagtattatt
agacatggagatgcaactgatgtgaggggcatcattcagaagatagtggacagtcacaag
gtaaagcatgtggcctgctatggattccgcctcagtcacctgcggtcggaggaggtacac
tggctccacgtggacatgggtgtctccagtgtgagggagaagtatgagctcgcccaccca
ccagaggagtggaagtatgaattaagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagacaagccaactctgaatttcttctaccaacaggtgaagagtgactacatg
ttagagatagctgatcaggtggaccaggagattgctttgaagttgggttgtctagaaata
cggcgatcatactgggagatgcgaggcaatgcgttagaaaagaagtctaactatgaagta
ttggaaaaagatgttggcttaaagcgattttttcctaagagtttactggattctgtcaag
gccaaaacattaagaaaactgatacaacaaacatttagacaatttgccaaccttaataga
gaagaaagtattctgaaattctttgaaatcctttctccagtgtatcgatatgacaaagaa
tgtttcaagtgtgctcttgggtcaagctggattatttcagtggaactggcaattggccca
gaagaagggatcagctacctgacagacaagggctgcaatcccacacatctggctgacttc
aaccaagtgcagacaattcagtattcaaacagtgaagacaaggacagaaaaggaatgctg
cagctcaaaatcgcaggtgcacctgagcctctgacagtgacggcaccatccctaactatc
gcagagaacatggctgacctgatagacggctactgtcggctggtgaacggagcaacgcaa
tcctttatcatcagaccccagaaagaaggtgaacgtgcattgccatcaataccaaagttg
ggcaacagcgaaaagcaaggagttcggacacacacagtctccgtgtcagagacagatgat
tatgctgagatcattgatgaagaagacacctacacaatgccctcaacgagggattatgag
atccaaagagaaagaatagaacttggacgatgtattggagaaggccagtttggagatgta
catcaaggagtgtatatgagtccggagaacccagctttggcggttgcaattaaaacatgt
aagaactgtacttcggacagcgtgagagagaaattccttcaagaagccttaacaatgcgt
cagtttgatcatcctcatattgtgaagctgattggagtcatcacagagaatcctgtctgg
ataatcatggagctgtgcaccctgggagagctgagatcatttttgcaagtaaggaagtac
agcttggatctggcatctttgatcctgtatgcttatcaacttagtacagcacttgcgtat
ctggagagcaaaagatttgtacacagggacattgctgctcggaatgttctggtatcctca
aatgattgtgtaaaattaggagactttggcttatcgcgatatatggaagacagtacttat
tacaaagcttccaaaggaaaattgcctataaaatggatggctccagagtcaatcaatttt
cgacggtttacctcagctagtgacgtatggatgtttggtgtatgtatgtgggagatactg
atgcatggtgtgaagccctttcaaggagtgaagaacaatgatgtgatcggtcgaattgaa
aatggggaaagattaccaatgcctccaaattgtcctcctaccctctacagccttatgacg
aaatgctgggcttatgaccccagcaggcggcccaggtttactgaacttaaagctcagctc
agcacaatcctggaagaggaaaaagctcagcaagaagaacgaatgaggatggaatccaga
agacaggccaccgtgtcttgggactctggagggtctgatgaagcaccgcccaagcccagt
aggcctggttatcctagtccaagatccagtgaaggattttaccccagccctcagcacatg
gtacagaccaatcattatcaggtctctggctaccctggttcacatggaatcacagccatg
gccggcagcatctacccaggccaagcatctcttctggaccagacagagtcatggaatcat
agacctcaagagatatccatgtggcagcccaacatggaggactcagcagtcttggacctg
cgaggcatcgggcaagtgctacccacccacctgatggaagagcggttgatccgacaacag
caggaaatggaagaagatcaacgctggctggaaaaagaggagagatttctgaaacctgac
gtgaggctctcccgaggcagtatcgaccgggaagacgggagtcttcagggcccaactgga
aaccaacacatctatcagcctgtgggtaaaccagatcctgcagctccaccaaagaaaccg
ccacgccccggagccccgagtcacctgggcagcattgccagcctcagcagcccaggggac
agctacaatgagggtgtcaagccatggaggcttcagccccaggaaatcagtccccctccc
actgccaacctggacaggtccaatgacaaggtatatgagaacgtgacgggcctggtgaaa
gccgtgattgagatgtccagcaaaatccagccagccccaccggaggagtacgtccccatg
gtgaaggaggttggcttggccctgcggacattactggccactgtggatgaaaccattcct
ggccttccagccagcacgcaccgagagatcgagatggcgcagaagctgctcaactccgac
ctgggcgagctcattggcaagatgaagctggcacagcaatatgtcatgaccagcctgcag
caggagtacaagaagcagatgctgactgctgcccatgccctggctgtggatgccaagaac
ctgctggatgtcattgaccaagcaagactgaaaatgctaggacagacgaggcctcactga
DBGET
integrated database retrieval system
