KEGG   Klebsiella aerogenes KCTC 2190: EAE_00345
Entry
EAE_00345         CDS       T01529                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
eae  Klebsiella aerogenes KCTC 2190
Pathway
eae03030  DNA replication
eae03410  Base excision repair
eae03420  Nucleotide excision repair
eae03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:eae00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    EAE_00345 (ligA)
   03410 Base excision repair
    EAE_00345 (ligA)
   03420 Nucleotide excision repair
    EAE_00345 (ligA)
   03430 Mismatch repair
    EAE_00345 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:eae03032]
    EAE_00345 (ligA)
   03400 DNA repair and recombination proteins [BR:eae03400]
    EAE_00345 (ligA)
Enzymes [BR:eae01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     EAE_00345 (ligA)
DNA replication proteins [BR:eae03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     EAE_00345 (ligA)
DNA repair and recombination proteins [BR:eae03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     EAE_00345 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     EAE_00345 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     EAE_00345 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      EAE_00345 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 Nlig-Ia DNA_ligase_ZBD PTCB-BRCT HHH RNA_ligase DUF2229 Prok-E2_C DZR_2
Other DBs
NCBI-ProteinID: AEG95007
UniProt: A0A0H3FQ42
LinkDB
Position
complement(67208..69223)
AA seq 671 aa
MEPIEQKLTELRTTLRHHEYLYHVMDTPEIPDAEYDRLMRELRELEAQHPELITPDSPTQ
RVGAAPLASFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLSDTADLTWCCELKLDGLA
VSILYENGVLMQAATRGDGTTGEDITSNVRTIRAIPLKLRGDNIPARLEVRGEVFLPQAG
FEKINEEARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPASHS
ARLQQFKQWGLPVSDRVKLCHSPEEVLTYYRQVEEDRPKLGFDIDGVVIKVDSLALQEQL
GFVARAPRWAVAFKFPAQEQMTFVNDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHN
ADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEHTREIIFPTHCPVCHSDVERVEG
EAVARCTGGLICGAQRKEALKHFVSRRALDVDGMGDKIIDQLVEKEYVHTPADLFRLSAG
KLTGLDRMGPKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAHFGTIEALEQ
ASIEELQKVPDVGIVVATHTFNFFAEESNREVIAQLRAEGVRWPAPVVVKAEEIDSPFAG
KTVVLTGSLSQLSRDDAKARLVALGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVI
DEAEMMRLLGE
NT seq 2016 nt   +upstreamnt  +downstreamnt
atggaaccaatcgaacaaaaactgactgaactgcgaaccacccttcgccatcatgaatat
ctgtatcatgttatggacaccccggagattcccgatgcggaatatgaccggctgatgcgc
gaactgcgcgaactcgaagcgcaacatcctgagctgattacccctgactcgccgacccaa
cgcgttggcgcggcgccgttggcctctttcagccagattcgccatgaagtgcccatgctg
tcgctggataacgtctttgatgaagagagtttcctcgcctttaacaaacgcgtgcaggac
cgtttaagcgatacggcggatctgacctggtgctgcgagctcaagctcgatggcctggcg
gtcagtatcctctatgaaaacggcgtgctgatgcaggcggcgacccgtggcgatggcacc
accggcgaggatattacctccaacgtgcgaaccattcgcgctattccgctgaagctacgc
ggcgacaatatcccggcgcggctggaagtgcgcggagaagtgttcctgccgcaggccgga
tttgaaaaaatcaatgaagaagcgcgccgcaccggcggcaaagtatttgctaacccgcgc
aatgccgccgcgggttcgttgcgccagttggatccgcgtattaccgcgaagcgaccgctt
actttcttctgctacggtgttggcgtgctggaaggcggtgaactaccggccagccactcc
gcgcgtttgcagcagtttaagcagtggggattgccggtgagcgaccgcgtgaagctgtgt
cattctccagaggaagtgcttacttactatcgccaggttgaagaagaccgtccgaaactt
ggttttgatattgacggcgtggtgattaaagtcgattcgctggcgctgcaggagcagctt
ggtttcgtcgcccgcgctccgcgctgggcggtggcctttaaattcccggcccaggagcag
atgacttttgtcaacgatgtggaattccaggttggccgtaccggagcgattacgccggta
gcgcgccttgaaccggtgcacgtggccggggtactggtcagtaacgccaccctgcataac
gccgacgaaatcgaacgtttaggtctgcgtattggcgacaaagtggtgattcgccgcgcg
ggggacgtgatcccgcaggtcgtcaacgtggtgctttctgaacgcccggaacatacgcgt
gaaatcatcttccccacacattgtccggtatgtcattccgatgttgaacgggtggaaggg
gaagcggtggcgcgctgtaccggcgggcttatctgcggcgcacagcgtaaagaagcgctg
aagcactttgtctcccgacgggcgctggatgtcgacggtatgggcgataaaatcatcgat
cagctggttgagaaagagtacgtccatacgccagccgatctgttccggctcagcgccggt
aagcttaccgggctggatcgcatgggaccgaaatcggcgcaaaatgtggtcaacgcgctg
gagaaagcgaaagagacgaccttcgcccgcttcctgtatgcgttaggtattcgcgaagtc
ggtgaggcgacagcagcgggactggcagcgcattttggcactattgaagcgctggaacag
gcttcgattgaggagctgcagaaggtgcctgacgtcgggattgtcgtcgccacacatact
tttaacttcttcgccgaagagagcaaccgcgaggtcatcgcgcaactgcgcgctgaaggc
gttcgctggccggcgccggtggtggtgaaggcggaagaaattgacagtccgtttgctggt
aaaaccgtggtattaaccggtagcctgagccagctgtcgcgcgatgatgccaaagcgcgg
ctggtcgcgctgggggcgaaagtcgccggcagcgtgtcgaagaaaaccgatctggtgatt
gccggcgaagcggcgggctctaagcttgcgaaggcgcaggagttaggcattgaggttatc
gacgaagccgaaatgatgcgcctgctgggagaataa

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