Klebsiella aerogenes KCTC 2190: EAE_11380
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Entry
EAE_11380 CDS
T01529
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
eae
Klebsiella aerogenes KCTC 2190
Pathway
eae00010
Glycolysis / Gluconeogenesis
eae00020
Citrate cycle (TCA cycle)
eae00620
Pyruvate metabolism
eae00785
Lipoic acid metabolism
eae01100
Metabolic pathways
eae01110
Biosynthesis of secondary metabolites
eae01120
Microbial metabolism in diverse environments
eae01200
Carbon metabolism
eae01210
2-Oxocarboxylic acid metabolism
Module
eae_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
eae00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
EAE_11380 (aceE)
00020 Citrate cycle (TCA cycle)
EAE_11380 (aceE)
00620 Pyruvate metabolism
EAE_11380 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
EAE_11380 (aceE)
Enzymes [BR:
eae01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
EAE_11380 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
PFO_beta_C
Motif
Other DBs
NCBI-ProteinID:
AEG97190
UniProt:
A0A0H3FP07
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Position
2438457..2441120
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AA seq
887 aa
AA seq
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MSERFQNDVDPIETRDWQQAIESVIREEGVERAQYLIDQLLSEARKGGVKVAAGAAAHNY
VNTIAVEDEPEYPGNLELERRIRSAIRWNAIMTVLRASKKDLELGGHMASYQSSATFYEV
CFNHFFRARTEKDGGDLVYFQGHISPGVYARAFLEGRLTEEQMNNFRQEVHGNGLSSYPH
PKLMPEFWQFPTVSMGLGPLGAIYQAKFLKYLEHRGLKDTSAQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFGGAGWNVIKVIWGGRWD
ELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWAL
NRGGHDPKKVYAALKKAQETKGQPTVILAHTIKGYGMGDTAEGKNIAHQVKKMNMDGVRY
VRDRFNVPVADADIEKLPYVTFPEGSEEHTYLHAQREKLNGYLPTRQPKFTEKLELPTLA
DFSALLEEQNKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNDLPMIPFYIYY
SMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PSYAYEVAVIMHDGLVRMYGEAQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETL
EGSKGKVQLLGSGSILRHVREAAQILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHP
LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIDKKVVADAIAKFDIDAEKVNPRLA
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaacgtttccagaatgacgtggatccgatcgaaactcgcgactggcaacaggcg
atcgaatcggtcatccgtgaagaaggtgttgagcgtgctcagtatctgatcgaccagctt
ctttctgaggcccgcaaaggcggcgtgaaagtagcggccggtgcggcagcgcataattac
gtcaacactattgccgttgaagatgaaccggaatacccgggcaatctggagctggaacgc
cgtattcgttcagcgatccgttggaacgccatcatgaccgttctgcgcgcatcgaagaaa
gatctggagctgggtggccacatggcatcctaccagtcttccgctaccttctacgaagtt
tgcttcaaccacttcttccgtgcgcgcactgagaaagacggcggcgatctggtttacttc
cagggccacatctctccgggcgtatatgcacgtgccttcctggaaggtcgtctgactgaa
gagcagatgaacaacttccgtcaggaagttcacggtaatggtctgtcctcttatccgcac
ccgaaactgatgccggaattctggcagttcccgaccgtatcaatggggctggggccgttg
ggcgcaatctatcaggctaaattcctgaaatatctggaacaccgtggtctgaaagacacc
tctgcgcaaaccgtttacgccttcctgggcgatggcgagatggatgagccggaatctaaa
ggcgctatcaccatcgcgacccgtgaaaaactggataacctggtcttcgtcatcaactgc
aacctgcagcgtctggacggcccggtcaccggtaacggtaaaatcattaacgaactggaa
ggcatcttcggtggtgctggctggaacgttatcaaggttatctggggcggtcgttgggat
gagctgctgcgtaaagacaccagcggtaagctgattcagctgatgaacgaaaccgttgac
ggcgactaccagaccttcaaatccaaagacggcgcctacgttcgtgagcacttcttcggt
aaatatccggaaaccgccgcgctggttgccgactggactgacgagcagatctgggccctg
aaccgtggcggtcacgatccgaagaaagtctacgctgcactgaaaaaagcgcaggaaacc
aaaggccagccgaccgtgattctggcgcataccattaaaggttatggtatgggcgacacc
gcggaaggtaaaaacatcgcgcaccaggttaagaaaatgaacatggacggcgttcgctac
gtccgcgatcgtttcaacgtgccggtggctgatgccgatatcgaaaaactgccgtacgtg
accttcccggaaggttctgaagagcacacttacctgcacgctcaacgtgaaaagctgaac
ggctacctgccgactcgtcagccgaaattcactgagaaactggagctgccgaccctggcc
gacttcagcgcgctgctggaagagcaaaacaaagaaatctctaccactatcgctttcgtt
cgtgccctgaacgtgatgctgaagaacaagtcgatcaaagatcgtctggtgccgatcatc
gccgatgaagcgcgtactttcggtatggaaggtctgttccgtcagatcggtatctacagc
ccgaacggccagcagtacaccccgcaggaccgtgagcaggttgcatactacaaagaagac
gagaaaggccagattctgcaggaaggtattaacgagctgggcgcaggcgcatcctggctg
gctgctgcgacctcctacagcaccaacgacctgccgatgattccgttctacatctactac
tcgatgttcggcttccagcgtatcggcgatctgtgctgggcggctggcgatcagcaggct
cgcggcttcctgattggcggtacttccggtcgtactacgctgaacggcgaaggtctgcag
cacgaagatggtcacagccacattcagtcgctgactatcccgaactgtatctcctacgac
ccgtcttacgcgtacgaagtcgctgtcatcatgcatgacggtctggtacgtatgtacggc
gaagcgcaagagaacgtttactactacatcactacactgaacgaaaactaccacatgccg
gccatgccggaaggcgccgaggaaggtatccgtaaaggtatctacaaactcgaaaccctc
gaaggtagcaaaggtaaagttcagctgctgggctccggttctatcctgcgtcacgttcgt
gaagcagcgcagatcctggcgaaagattacggcgtaggttctgacgtgtatagcgtcacc
tccttcaccgaactggcgcgtgatggccaggattgcgaacgctggaacatgctgcacccg
ctggaaactccgcgcgtaccgtacatcgctcaggtgatgaacgacgctccggctgtagca
tccactgactatatgaaactgttcgccgagcaggttcgtacttacgtaccggctgatgat
taccgcgtactgggtaccgatggcttcggtcgttccgacagccgtgaaaacctgcgtcac
cacttcgaagttgatgcttcctacgtggtcgttgcggcgctgggcgaactggctaaacgt
ggtgaaatcgataagaaagttgtggctgacgccattgctaaattcgacatcgatgcagaa
aaagttaacccgcgtctggcgtaa
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