Equus asinus (ass): 106824941
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Entry
106824941 CDS
T04645
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
eai
Equus asinus (ass)
Pathway
eai04120
Ubiquitin mediated proteolysis
eai04144
Endocytosis
eai04330
Notch signaling pathway
eai04668
TNF signaling pathway
eai04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
eai00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
106824941 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
106824941 (ITCH)
04668 TNF signaling pathway
106824941 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
106824941 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
106824941 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
eai04131
]
106824941 (ITCH)
04121 Ubiquitin system [BR:
eai04121
]
106824941 (ITCH)
Enzymes [BR:
eai01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
106824941 (ITCH)
Membrane trafficking [BR:
eai04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
106824941 (ITCH)
Ubiquitin system [BR:
eai04121
]
Ubiquitin ligases (E3)
HECT type E3
106824941 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
106824941
NCBI-ProteinID:
XP_014686965
UniProt:
A0A8C4PKA6
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All DBs
Position
15:25538297..25660787
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AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
SSPKWKQPLTLIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLESEVVTNGETTCSESASQNDDSSRLKDETRASTNGS
DDPEDVGSVENRRVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPLTNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLTMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccgagt
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaataca
agtagtcccaaatggaagcaaccccttacacttatcgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacgctgaaatctgacgttttgttgggaactgctgcatta
gatatctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagagccgacagagacaattggagacttgtcagtttgtcttgat
gggctgcagttagagtctgaagttgttaccaatggtgaaactacgtgttcagaaagtgct
tcacagaatgatgatagctccagactcaaggacgaaacaagagcaagcacaaatggatca
gatgaccctgaggacgtagggtctgttgaaaataggagggtcaatgggaataattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccatcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgat
ggatctagcacaggctctctgccactaacgaatacaaattcaaatacatctgaaggagca
acgtctggattaataattcctcttactatatctggaggctcaggccctaggccattaaat
cctgtacctcaagctcccctaccacctggttgggagcagagagtggaccagcatgggcga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccaacattggaatccgtccggaactatgaacagtggcag
ctccaacgtagccaacttcaaggagcaatgcagcagtttaatcagagattcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatccccttggtcccctgcca
cctggatgggagaagagaacggacagcaatggtagagtatattttgtcaaccacaatact
cgtattacacaatgggaagatcccagaagtcaaggtcaactaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagtggatggaattccatattttgtggaccacaataga
agaacaaccacctatatagatccccgcactggaaaatctgccctagacaatggaccccag
atagcctatgtacgagacttcaaggcaaaggttcagtatttccggttctggtgtcagcaa
ctgaccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaggattcc
tttcagcagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaacccagcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgccatggctctgttccatgggaaattcattgacacaggtttttctttg
ccattctataagcgtatcttgaacaaaccagttggactaaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctctgttgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cccaatggcggcaatattcttgtaacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttttttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggaattagaggtccta
ttatgtggaatgcaagagattgatctgaatgactggcaaagacatgcaatctaccgtcat
tacactaggacaagcaagcaaatcatgtggttttggcagtttgttaaagaaatcgataat
gagaagagaatgagacttctgcagtttgttactggaacctgccgattgcccgttggagga
tttgctgacctcatggggagcaatggaccacagaaattctgcattgaaaaagttgggaaa
gaaaattggttacccagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgccattgaagaaactgaaggatttgga
caagagtaa
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