Equus asinus (ass): 106825034 Help Entry 106825034         CDS       T04645                                  Symbol TNF Name (RefSeq) tumor necrosis factor isoform X1   KO K03156   tumor necrosis factor superfamily, member 2 Organism eai  Equus asinus (ass) Pathway eai01523   Antifolate resistance eai04010   MAPK signaling pathway eai04060   Cytokine-cytokine receptor interaction eai04061   Viral protein interaction with cytokine and cytokine receptor eai04064   NF-kappa B signaling pathway eai04071   Sphingolipid signaling pathway eai04150   mTOR signaling pathway eai04210   Apoptosis eai04217   Necroptosis eai04350   TGF-beta signaling pathway eai04380   Osteoclast differentiation eai04612   Antigen processing and presentation eai04620   Toll-like receptor signaling pathway eai04621   NOD-like receptor signaling pathway eai04622   RIG-I-like receptor signaling pathway eai04625   C-type lectin receptor signaling pathway eai04640   Hematopoietic cell lineage eai04650   Natural killer cell mediated cytotoxicity eai04657   IL-17 signaling pathway eai04660   T cell receptor signaling pathway eai04664   Fc epsilon RI signaling pathway eai04668   TNF signaling pathway eai04920   Adipocytokine signaling pathway eai04930   Type II diabetes mellitus eai04931   Insulin resistance eai04932   Non-alcoholic fatty liver disease eai04933   AGE-RAGE signaling pathway in diabetic complications eai04936   Alcoholic liver disease eai04940   Type I diabetes mellitus eai05010   Alzheimer disease eai05014   Amyotrophic lateral sclerosis eai05020   Prion disease eai05022   Pathways of neurodegeneration - multiple diseases eai05132   Salmonella infection eai05133   Pertussis eai05134   Legionellosis eai05135   Yersinia infection eai05140   Leishmaniasis eai05142   Chagas disease eai05143   African trypanosomiasis eai05144   Malaria eai05145   Toxoplasmosis eai05146   Amoebiasis eai05152   Tuberculosis eai05160   Hepatitis C eai05161   Hepatitis B eai05163   Human cytomegalovirus infection eai05164   Influenza A eai05165   Human papillomavirus infection eai05166   Human T-cell leukemia virus 1 infection eai05168   Herpes simplex virus 1 infection eai05169   Epstein-Barr virus infection eai05170   Human immunodeficiency virus 1 infection eai05171   Coronavirus disease - COVID-19 eai05205   Proteoglycans in cancer eai05310   Asthma eai05321   Inflammatory bowel disease eai05322   Systemic lupus erythematosus eai05323   Rheumatoid arthritis eai05330   Allograft rejection eai05332   Graft-versus-host disease eai05410   Hypertrophic cardiomyopathy eai05414   Dilated cardiomyopathy eai05417   Lipid and atherosclerosis eai05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:eai00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     106825034 (TNF)    04350 TGF-beta signaling pathway     106825034 (TNF)    04064 NF-kappa B signaling pathway     106825034 (TNF)    04668 TNF signaling pathway     106825034 (TNF)    04071 Sphingolipid signaling pathway     106825034 (TNF)    04150 mTOR signaling pathway     106825034 (TNF)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     106825034 (TNF)    04061 Viral protein interaction with cytokine and cytokine receptor     106825034 (TNF)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     106825034 (TNF)    04217 Necroptosis     106825034 (TNF)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     106825034 (TNF)    04620 Toll-like receptor signaling pathway     106825034 (TNF)    04621 NOD-like receptor signaling pathway     106825034 (TNF)    04622 RIG-I-like receptor signaling pathway     106825034 (TNF)    04625 C-type lectin receptor signaling pathway     106825034 (TNF)    04650 Natural killer cell mediated cytotoxicity     106825034 (TNF)    04612 Antigen processing and presentation     106825034 (TNF)    04660 T cell receptor signaling pathway     106825034 (TNF)    04657 IL-17 signaling pathway     106825034 (TNF)    04664 Fc epsilon RI signaling pathway     106825034 (TNF)   09152 Endocrine system    04920 Adipocytokine signaling pathway     106825034 (TNF)   09158 Development and regeneration    04380 Osteoclast differentiation     106825034 (TNF)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     106825034 (TNF)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     106825034 (TNF)    05170 Human immunodeficiency virus 1 infection     106825034 (TNF)    05161 Hepatitis B     106825034 (TNF)    05160 Hepatitis C     106825034 (TNF)    05171 Coronavirus disease - COVID-19     106825034 (TNF)    05164 Influenza A     106825034 (TNF)    05168 Herpes simplex virus 1 infection     106825034 (TNF)    05163 Human cytomegalovirus infection     106825034 (TNF)    05169 Epstein-Barr virus infection     106825034 (TNF)    05165 Human papillomavirus infection     106825034 (TNF)   09171 Infectious disease: bacterial    05132 Salmonella infection     106825034 (TNF)    05135 Yersinia infection     106825034 (TNF)    05133 Pertussis     106825034 (TNF)    05134 Legionellosis     106825034 (TNF)    05152 Tuberculosis     106825034 (TNF)   09174 Infectious disease: parasitic    05146 Amoebiasis     106825034 (TNF)    05144 Malaria     106825034 (TNF)    05145 Toxoplasmosis     106825034 (TNF)    05140 Leishmaniasis     106825034 (TNF)    05142 Chagas disease     106825034 (TNF)    05143 African trypanosomiasis     106825034 (TNF)   09163 Immune disease    05310 Asthma     106825034 (TNF)    05322 Systemic lupus erythematosus     106825034 (TNF)    05323 Rheumatoid arthritis     106825034 (TNF)    05321 Inflammatory bowel disease     106825034 (TNF)    05330 Allograft rejection     106825034 (TNF)    05332 Graft-versus-host disease     106825034 (TNF)   09164 Neurodegenerative disease    05010 Alzheimer disease     106825034 (TNF)    05014 Amyotrophic lateral sclerosis     106825034 (TNF)    05020 Prion disease     106825034 (TNF)    05022 Pathways of neurodegeneration - multiple diseases     106825034 (TNF)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     106825034 (TNF)    05418 Fluid shear stress and atherosclerosis     106825034 (TNF)    05410 Hypertrophic cardiomyopathy     106825034 (TNF)    05414 Dilated cardiomyopathy     106825034 (TNF)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     106825034 (TNF)    04940 Type I diabetes mellitus     106825034 (TNF)    04936 Alcoholic liver disease     106825034 (TNF)    04932 Non-alcoholic fatty liver disease     106825034 (TNF)    04931 Insulin resistance     106825034 (TNF)    04933 AGE-RAGE signaling pathway in diabetic complications     106825034 (TNF)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     106825034 (TNF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:eai04052]     106825034 (TNF)    00536 Glycosaminoglycan binding proteins [BR:eai00536]     106825034 (TNF) Cytokines and neuropeptides [BR:eai04052]  Cytokines   Tumor necrosis fators    106825034 (TNF) Glycosaminoglycan binding proteins [BR:eai00536]  Heparan sulfate / Heparin   Cytokines    106825034 (TNF) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TNF Motif Other DBs NCBI-GeneID:  106825034 NCBI-ProteinID:  XP_014687090 UniProt:  A0A9L0JZG0 LinkDB All DBs Position 8:60174074..60176849 Genome browser AA seq 253 aa AA seqDB search MPQGSTISQLDLSPSGKDIMSTESMIRDVELAEEELAKKAGGPQGSRRCLCLSLFSFLLV AGATTLFCLLHFGVIGPQREEQLPNAFQSINPLAQTLRSSSRTPSDKPVAHVVANPQAEG QLQWLSGRANALLANGVKLTDNQLVVPLDGLYLIYSQVLFKGQGCPSTHVLLTHTISRLA VSYPSKVNLLSAIKSPCHTETPEQAEAKPWYEPIYLGGVFQLEKGDRLSAEINLPNYLDF AESGQVYFGIIAL NT seq 762 nt NT seq  +upstreamnt  +downstreamnt atgccccagggctcgaccatctcccagctggacttgagcccctctggaaaggacatcatg agcactgaaagcatgatccgagatgtggagctggcagaggaggagctcgccaagaaggca gggggcccccagggctccagacggtgcttgtgcctcagcctcttctccttcctccttgtc gcaggagccaccacactcttctgcctgctgcactttggggtgatcggcccccagagggaa gagcagttaccgaatgccttccagtcaatcaaccctctggcccagacactcagatcatct tctcgaaccccaagtgacaagcctgtagcccatgttgtagcaaacccccaagccgagggg cagctccagtggctgagtgggcgtgcaaatgccctcctggccaatggcgtgaagctgaca gacaaccagctggtggtaccattggatgggctgtacctcatctactcccaggtcctcttc aaaggccaaggctgcccttccacccatgtgctcctcacccacaccatcagccgcttagct gtctcctacccgtccaaggtcaacctcctctctgccatcaagagcccttgccacacggag accccagagcaggctgaagccaagccctggtatgagcccatctacctgggaggagtcttc cagctggagaagggtgatcgactcagcgctgagatcaatctgcccaactatctcgacttt gcggagtccgggcaggtctactttgggatcattgccctgtga

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