Equus asinus (ass): 106826352
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Entry
106826352 CDS
T04645
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
eai
Equus asinus (ass)
Pathway
eai01524
Platinum drug resistance
eai03440
Homologous recombination
eai03460
Fanconi anemia pathway
eai04120
Ubiquitin mediated proteolysis
eai04151
PI3K-Akt signaling pathway
eai05206
MicroRNAs in cancer
eai05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
eai00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
106826352 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
106826352 (BRCA1)
03460 Fanconi anemia pathway
106826352 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
106826352 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
106826352 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
106826352 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
106826352 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
eai01009
]
106826352 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
eai04121
]
106826352 (BRCA1)
03036 Chromosome and associated proteins [BR:
eai03036
]
106826352 (BRCA1)
03400 DNA repair and recombination proteins [BR:
eai03400
]
106826352 (BRCA1)
Enzymes [BR:
eai01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
106826352 (BRCA1)
Protein phosphatases and associated proteins [BR:
eai01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
106826352 (BRCA1)
Ubiquitin system [BR:
eai04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
106826352 (BRCA1)
Multi subunit type E3
BRCC complex
106826352 (BRCA1)
Chromosome and associated proteins [BR:
eai03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
106826352 (BRCA1)
DNA repair and recombination proteins [BR:
eai03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
106826352 (BRCA1)
BRCA1-A complex
106826352 (BRCA1)
BRCA1-B complex
106826352 (BRCA1)
BRCA1-C complex
106826352 (BRCA1)
BRCA complex
106826352 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
106826352 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_3
zf-C3HC4_4
zf-RING_2
zf-RING_5
RING_XB3-XBAT31
BRCT_2
zf-RING_6
zf-Nse
zf-ANAPC11
zf-RING_10
zf-rbx1
Prok-RING_4
Baculo_IE-1
Motif
Other DBs
NCBI-GeneID:
106826352
NCBI-ProteinID:
XP_014689130
UniProt:
A0A8C4LUL8
LinkDB
All DBs
Position
13:complement(44593779..44648984)
Genome browser
AA seq
1856 aa
AA seq
DB search
MDVSADRVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNDITKRSLQESTRFSQLVEELLRIIHAFELDTGLQFAHSYSFSKKENDSPERLKE
EVSIIQSMGYRNRAKRHRQSEPENPTLQETSLSVHLSNLGIVRSLRTKQQIQPQNKSIYI
ELGSDSSEDTVNKASYCSLGDHELLQITPQGARAEASLNPTKKAACEFSEKAITNIEHHQ
SSNKDLTTTEKHAAEKHPEKYQGISVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE
KAEFCNKSKQPGLAKSQQSRWAESKETCNDRQAPNSEEKLVLNADPLYGREELNKQKPPR
SDSPRDSQDVPWITLNSSIQKVNEWFSRSEEMLTSDDSCDRGPESNTEVAGAVEVPNEVR
GYSGSSEKIDLMAGDPSSALICESERVRSKPVENNIEDRIFGKTYRRKASFPNLSHITED
LIIGASAIEPQITQERPLTNRLKHKRRTSSGLHPEDFIKKVDLAVVQKTPEKIIEGTDQI
EQNSHVMHITPNGHGNETKGDYVQNEKNANLTESLETESAFRTKAEPISSSIGNLELELN
IHSSKAPKKNRLRRKSCTKQIHALELVVSKNPSPPNHTELQIDSCSSSEEMKKKNSDQMP
VRHSKKLQLMEDKEPATGAEKSNKPNEQINKRLASDAFPELKLTNIPGFFTNCSSSNKLH
EFVNPSLQREEIEQNLGANQLSNSAKDPKDLILSGGKCLQAERSVESSGISLVPDTDYGT
QDSISLLEADTLGKAKTAPNQCANLCAAIENPKELTHDCSKDTRNDTQGVKDPLRREVNH
TQETSIEMEESEFDTQYLQNMFKVSKRQSFALFSNPGSPEKKCATVSAHSRSLRKRSPKV
TLKCGQKEGKEGKKESKIKNVQSVHTTVGFPVICQKDKKPGDYVKCSTKEASRLCQSSQF
RGNETELITANKHGISQNPYYIPSLSPIRSSVKTVCQKNLPEGKLEEQSLSPERAMGNES
IVQSTVSTISQNNIRESTLKEVSSSSINEVGSSINEVGSSGEHIQAELGRNRGPKLNAIL
RLGLMQPEVYKQSLPISNCKHPEIKRQGENEVVQAVNADFSPCLISDNLEQPMGSSCASQ
VCSETPDDLLNDDEIKENISFAESGVKERSAVFSKSVQKGKFRRSPSPIGRTCLAQGHQR
RARKLESSEENTSSEDEELPCFQHLLFGKVTNLPSQSTSHAAATEGLSKKTEESLVSLQN
SLDDCSHQVALAEACQEHHLSEEARCSGSLFSSQCSALEDLPANTNTQEPVLMFDPPSKQ
VREQSENHEVVSDKELVSDDDEREPGLEEDSHHEEQSVDSILDEVASGYVSETNLSEDCS
GLSSQSDILTTQQRDTMQDNLIKLQQKMAELEAVLEQHGSQPSNRSPSLIADSCASEDLL
NPEQNTSERAVLTSEKSSEYPISQNPENLSADKFQISLDSSTSKNREPEMERSSPSKSQL
LDNRWCVHSHSRSLQNRNCPSQKELIKVVDAEEQQLTKSEAQDLMEQSYLPRQDLEATPY
LESGISLFSHEPESDPSEERALEAAHVCSMPASTSAMKSLQFRVEESAKSPAAAHTTNIV
GSNVKEDSVSREKPEMISSTKRVIRRISMVASGLTPKEFMLVHKFARKHHITLTNLVTEE
TTHVIMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKVLDEHDFEVRGDVVNG
RNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVRLCGASVVKEPSSFTFSEG
THPVVVVQPDAWTEDSGFHMTGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQVP
NT seq
5571 nt
NT seq
+upstream
nt +downstream
nt
atggatgtatctgcggatcgcgttgaagaagtacaaaatgttctcaatgctatgcagaaa
atcttagagtgtccgatctgtctggagttgatcaaagagcccgtttccacaaaatgtgac
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacag
tgtcctttgtgtaagaatgatataaccaaaagaagcctccaagaaagtacaagatttagt
caacttgttgaagagctgttgagaatcattcatgcttttgaacttgacacaggactgcag
tttgcacatagttatagcttttcaaaaaaggaaaatgactctcctgagcgtctaaaggag
gaagtttctatcatccaaagtatgggctaccgaaaccgtgccaaaagacatcgacagagt
gaacctgaaaatcctaccttgcaggaaaccagtcttagtgtccacctctctaaccttgga
attgtgagatctctgaggacaaagcaacagatacaacctcagaataagtctatctacatt
gaattgggatctgattcttctgaagatacagttaataaggcaagttattgcagtttggga
gaccacgaattgttacaaatcactcctcaaggagccagggctgaagccagtttgaatcct
acaaaaaaggctgcttgtgagttttctgagaaggccataacaaatattgaacatcatcaa
tccagtaataaagatttgaccaccactgagaagcatgcagctgagaagcatccagaaaag
tatcagggtatttctgtttcaaacttgcatgtggagccatgtggcacaaatactcatgcc
agctcattgcagcatgagaacagcagtttattactcactaaagacagaatgaatgtagaa
aaggctgaattctgtaataaaagcaaacagcctggcttagcaaagagccaacagagcaga
tgggctgaaagtaaggaaacatgtaatgataggcaggcccccaactcagaggaaaagcta
gttctgaatgctgatccgctgtatgggagagaagaactgaataagcagaaacctccacgc
tctgacagtcctagagactcccaagatgttccttggataacactgaatagtagcatacag
aaagttaatgagtggttttccagaagtgaggaaatgttaacttctgatgactcatgtgac
agagggcctgaatcaaatacagaagtagctggtgcagtagaagttccaaatgaagtacgt
ggatattctggttcttcagagaaaatagacttaatggccggtgatccttctagtgcttta
atatgtgaaagtgaaagagtccgctccaaaccggtagagaataatattgaagatagaata
tttgggaaaacctatcggaggaaggcaagcttccctaacttgagccacataactgaagat
ctaattataggggcatctgctatagaacctcagattacacaagagcgtccactcacaaat
agactgaagcataaaaggagaacgtcatcaggccttcatcctgaggattttatcaagaaa
gtagatttggcagttgtccaaaagactcctgaaaagataattgagggaactgaccaaata
gagcagaacagtcatgtgatgcatattactcctaatggtcatgggaatgaaacaaaaggc
gattatgttcagaacgagaaaaacgctaacctaacagaatcattggagacagaatctgct
ttcagaactaaagctgaacctataagcagcagcataggcaatctggaactggaattaaat
atccacagttcaaaagcacctaagaagaataggctgaggaggaagtcttgtaccaagcag
attcatgcacttgaactagtagtcagtaaaaatccaagcccacctaatcatactgaacta
caaatcgatagttgttctagtagtgaagagatgaagaaaaaaaattctgaccaaatgccg
gtcagacacagcaaaaagcttcaactcatggaagataaagaacctgccactggagccgaa
aagagtaacaagccaaatgaacaaataaataaaagacttgccagtgatgcttttccagag
ctaaaattaacaaacatacctggtttttttactaactgttcaagttctaataaacttcat
gagtttgtcaatcctagccttcaaagagaagaaatagaacagaacctaggagcaaatcaa
ctgtctaatagtgccaaagaccccaaagatctgatattaagtggaggaaaatgtttgcaa
gctgaaagatctgtagagagttccggtatttcattggtacctgatactgattatgggact
caggatagtatctcactgctggaagctgacaccctagggaaggcaaaaacagcaccaaat
caatgtgcaaatctatgcgcagcaattgaaaaccccaaggaacttacccatgattgttct
aaggatactagaaatgatacacagggcgttaaggatccattgagacgtgaagttaaccac
actcaggagacaagcatagaaatggaagagagtgaatttgatacgcagtatctacagaat
atgttcaaggtttcaaagcgtcagtcatttgctctgttttcaaatccaggaagtccagaa
aagaagtgtgcaacagtcagtgcccactccaggtccttaaggaaacgaagtccaaaagtc
actcttaaatgtggacaaaaagaaggaaaggagggaaagaaagagtctaaaatcaagaat
gtgcagtcagttcacacaactgtgggctttcctgtgatttgtcagaaagataagaagcca
ggtgactatgtcaaatgtagcacaaaagaagcctctaggctttgtcagtcatctcagttc
agaggcaacgaaactgaacttattactgcaaataaacatggaatttcacaaaacccatat
tatataccatcactttctcccatcaggtcatctgttaaaactgtatgtcagaaaaacctg
ccagagggaaagcttgaggaacagtcactgtcacctgaaagagcaatgggaaatgagagc
attgttcaaagtacagtgagcacaattagccaaaataacattagagaaagcacattgaaa
gaagtcagctcaagcagtattaatgaagtaggctctagtattaatgaagtaggttccagt
ggtgaacacattcaagcagaactaggcagaaacagaggacctaaattaaatgctattctc
agattaggtcttatgcaacctgaagtctataagcaaagtcttcctataagtaattgtaaa
catccggaaataaaaaggcaaggagaaaatgaagtagttcaggctgttaacgcagacttt
tctccgtgtctaatttcagataacctagaacaacctatgggaagtagttgtgcttctcag
gtttgttctgagacacctgatgacctgttaaatgatgacgaaataaaggaaaatatcagc
tttgctgaaagtggcgttaaggaaagatctgccgtttttagcaaaagcgtccagaaagga
aagttcagaaggagtcctagccctataggccgtacgtgtttggctcagggtcaccaaaga
cgggccaggaaattagagtcctcagaagagaacacgtctagtgaggatgaagagcttccc
tgcttccaacacttactatttggtaaagtaaccaatctaccttctcaatctaccagccat
gctgctgccacggaaggtctgtctaagaaaacagaggagagcctagtatcattgcagaat
agcttagatgactgcagtcaccaggtggcgttggcagaggcatgccaggaacatcacctg
agtgaggaagcgagatgttccggtagcttattttcttcccagtgcagtgcgttggaagac
ttgcccgctaatacgaacacccaggagcctgtcttgatgtttgatcctccttccaaacaa
gtgagggaacaatctgaaaaccacgaagttgtgagtgacaaggaattggtttcagatgat
gatgaacgggaacctggcctggaagaggatagtcaccacgaagagcagagtgtggattca
atcttagatgaagtagcgtccgggtatgtgagtgaaacaaatctctcggaagactgttca
gggctctcctctcagagtgatattttaaccactcagcagagggataccatgcaagataac
ctgataaagcttcagcagaagatggccgagctggaagctgtgttagagcagcacgggagc
cagccttctaaccgctccccttccctcatagctgattcttgtgcctctgaggacctgcta
aatccagaacaaaacacatcagaaagagcagtattaacttcagagaaaagtagtgaatat
cctataagccagaatccagaaaacctttctgctgacaagtttcaaatatctctggatagt
tccaccagtaaaaatagagaaccagaaatggaaaggtcttccccttctaaatcccagttg
ttagataataggtggtgtgtgcacagtcactcaaggagtcttcagaacagaaactgccca
tctcaaaaggagctcattaaggttgttgatgcggaggagcagcaactgacaaaatctgag
gcccaagatttaatggagcagtcttatttgccaagacaagatctagaggcaaccccttac
ctggaatctggaattagcctgttctctcatgagcctgagtctgatccctctgaagagaga
gctctagaggcagctcatgtttgcagcatgccggcttcaacctctgcgatgaaatcactc
caatttcgagttgaagaatctgccaagagtccagctgctgctcatactactaatattgtt
gggtctaatgtgaaggaagacagtgtgagcagggagaagccagaaatgatatcttcgacc
aaaagagtcatcagaagaatatccatggtggcctcaggcttgaccccaaaagaatttatg
cttgtgcacaagtttgccagaaaacaccacatcactttaactaatctagttactgaagag
actactcatgtcattatgaaaacagatgctgaatttgtgtgtgaacggacactgaaatat
tttctgggaattgcaggaggaaaatgggtagttagctatttctgggtgacccagtctatt
aaagaaagaaaggtgctggatgagcatgattttgaagtcagaggagatgttgtgaatgga
agaaaccaccaagggccaaagcgagcaagagaatcccaggacagaaagatcttcaggggc
ctagaaatctgttgctatgggccatttaccaacatgcccacagatcaactagagtggatg
gtgcgcctctgtggggcttctgtggtgaaggagccttcatcgttcaccttcagtgagggt
actcacccagttgtggtcgtgcaaccggacgcctggacagaggacagtggcttccatatg
actgggcagatgtgtgaggcacctgtggtgacccgagagtgggtgttggacagcgtagcc
ctctaccagtgccaggagctggacacctacctcataccccaggttccctag
DBGET
integrated database retrieval system
