KEGG   Equus asinus (ass): 106830292
Entry
106830292         CDS       T04645                                 
Symbol
GRB2
Name
(RefSeq) growth factor receptor-bound protein 2 isoform X1
  KO
K04364  growth factor receptor-bound protein 2
Organism
eai  Equus asinus (ass)
Pathway
eai01521  EGFR tyrosine kinase inhibitor resistance
eai01522  Endocrine resistance
eai04010  MAPK signaling pathway
eai04012  ErbB signaling pathway
eai04014  Ras signaling pathway
eai04062  Chemokine signaling pathway
eai04068  FoxO signaling pathway
eai04072  Phospholipase D signaling pathway
eai04150  mTOR signaling pathway
eai04151  PI3K-Akt signaling pathway
eai04380  Osteoclast differentiation
eai04510  Focal adhesion
eai04517  IgSF CAM signaling
eai04540  Gap junction
eai04550  Signaling pathways regulating pluripotency of stem cells
eai04630  JAK-STAT signaling pathway
eai04650  Natural killer cell mediated cytotoxicity
eai04660  T cell receptor signaling pathway
eai04662  B cell receptor signaling pathway
eai04664  Fc epsilon RI signaling pathway
eai04714  Thermogenesis
eai04722  Neurotrophin signaling pathway
eai04910  Insulin signaling pathway
eai04912  GnRH signaling pathway
eai04915  Estrogen signaling pathway
eai04917  Prolactin signaling pathway
eai04926  Relaxin signaling pathway
eai04935  Growth hormone synthesis, secretion and action
eai05034  Alcoholism
eai05160  Hepatitis C
eai05161  Hepatitis B
eai05163  Human cytomegalovirus infection
eai05165  Human papillomavirus infection
eai05200  Pathways in cancer
eai05203  Viral carcinogenesis
eai05205  Proteoglycans in cancer
eai05206  MicroRNAs in cancer
eai05207  Chemical carcinogenesis - receptor activation
eai05208  Chemical carcinogenesis - reactive oxygen species
eai05210  Colorectal cancer
eai05211  Renal cell carcinoma
eai05213  Endometrial cancer
eai05214  Glioma
eai05215  Prostate cancer
eai05220  Chronic myeloid leukemia
eai05221  Acute myeloid leukemia
eai05223  Non-small cell lung cancer
eai05224  Breast cancer
eai05225  Hepatocellular carcinoma
eai05226  Gastric cancer
eai05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:eai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    106830292 (GRB2)
   04012 ErbB signaling pathway
    106830292 (GRB2)
   04014 Ras signaling pathway
    106830292 (GRB2)
   04630 JAK-STAT signaling pathway
    106830292 (GRB2)
   04068 FoxO signaling pathway
    106830292 (GRB2)
   04072 Phospholipase D signaling pathway
    106830292 (GRB2)
   04151 PI3K-Akt signaling pathway
    106830292 (GRB2)
   04150 mTOR signaling pathway
    106830292 (GRB2)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    106830292 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    106830292 (GRB2)
   04540 Gap junction
    106830292 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    106830292 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    106830292 (GRB2)
   04660 T cell receptor signaling pathway
    106830292 (GRB2)
   04662 B cell receptor signaling pathway
    106830292 (GRB2)
   04664 Fc epsilon RI signaling pathway
    106830292 (GRB2)
   04062 Chemokine signaling pathway
    106830292 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    106830292 (GRB2)
   04912 GnRH signaling pathway
    106830292 (GRB2)
   04915 Estrogen signaling pathway
    106830292 (GRB2)
   04917 Prolactin signaling pathway
    106830292 (GRB2)
   04926 Relaxin signaling pathway
    106830292 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    106830292 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    106830292 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    106830292 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    106830292 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    106830292 (GRB2)
   05206 MicroRNAs in cancer
    106830292 (GRB2)
   05205 Proteoglycans in cancer
    106830292 (GRB2)
   05207 Chemical carcinogenesis - receptor activation
    106830292 (GRB2)
   05208 Chemical carcinogenesis - reactive oxygen species
    106830292 (GRB2)
   05203 Viral carcinogenesis
    106830292 (GRB2)
   05231 Choline metabolism in cancer
    106830292 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    106830292 (GRB2)
   05225 Hepatocellular carcinoma
    106830292 (GRB2)
   05226 Gastric cancer
    106830292 (GRB2)
   05214 Glioma
    106830292 (GRB2)
   05221 Acute myeloid leukemia
    106830292 (GRB2)
   05220 Chronic myeloid leukemia
    106830292 (GRB2)
   05211 Renal cell carcinoma
    106830292 (GRB2)
   05215 Prostate cancer
    106830292 (GRB2)
   05213 Endometrial cancer
    106830292 (GRB2)
   05224 Breast cancer
    106830292 (GRB2)
   05223 Non-small cell lung cancer
    106830292 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    106830292 (GRB2)
   05160 Hepatitis C
    106830292 (GRB2)
   05163 Human cytomegalovirus infection
    106830292 (GRB2)
   05165 Human papillomavirus infection
    106830292 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    106830292 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    106830292 (GRB2)
   01522 Endocrine resistance
    106830292 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:eai04131]
    106830292 (GRB2)
Membrane trafficking [BR:eai04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    106830292 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 SH2_2 DUF5093 DUF7145 hSH3 SH3_4
Other DBs
NCBI-GeneID: 106830292
NCBI-ProteinID: XP_014695303
LinkDB
Position
13:complement(58128199..58190220)
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctactgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagaa
ctcaatgggaaagatggcttcattcccaagaattacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcatgat
ggggcctttcttatccgagagagtgagagtgctcctggggatttctccctctctgtcaag
tttggaaacgacgtgcagcacttcaaggtgctccgagatggagctgggaagtatttcctt
tgggtggtgaagttcaattctttgaatgagctggtagattatcacagatccacatctgtc
tccagaaaccagcagatatttctccgggacatagaacaggtgccacagcagccgacgtat
gtccaagccctctttgactttgatccccaggaggatggagagctgggattccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcttgccacggg
cagaccggcatgtttccccgcaattatgtcacccctgtgaaccggaacgtctaa

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