KEGG   Equus asinus (ass): 106834253
Entry
106834253         CDS       T04645                                 
Symbol
SHC2
Name
(RefSeq) LOW QUALITY PROTEIN: SHC-transforming protein 2
  KO
K17447  SHC-transforming protein 2
Organism
eai  Equus asinus (ass)
Pathway
eai01521  EGFR tyrosine kinase inhibitor resistance
eai01522  Endocrine resistance
eai04012  ErbB signaling pathway
eai04014  Ras signaling pathway
eai04062  Chemokine signaling pathway
eai04072  Phospholipase D signaling pathway
eai04370  VEGF signaling pathway
eai04510  Focal adhesion
eai04650  Natural killer cell mediated cytotoxicity
eai04722  Neurotrophin signaling pathway
eai04910  Insulin signaling pathway
eai04915  Estrogen signaling pathway
eai04917  Prolactin signaling pathway
eai04926  Relaxin signaling pathway
eai04935  Growth hormone synthesis, secretion and action
eai05034  Alcoholism
eai05100  Bacterial invasion of epithelial cells
eai05214  Glioma
eai05220  Chronic myeloid leukemia
eai05224  Breast cancer
eai05225  Hepatocellular carcinoma
eai05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:eai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    106834253 (SHC2)
   04014 Ras signaling pathway
    106834253 (SHC2)
   04370 VEGF signaling pathway
    106834253 (SHC2)
   04072 Phospholipase D signaling pathway
    106834253 (SHC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    106834253 (SHC2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    106834253 (SHC2)
   04062 Chemokine signaling pathway
    106834253 (SHC2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    106834253 (SHC2)
   04915 Estrogen signaling pathway
    106834253 (SHC2)
   04917 Prolactin signaling pathway
    106834253 (SHC2)
   04926 Relaxin signaling pathway
    106834253 (SHC2)
   04935 Growth hormone synthesis, secretion and action
    106834253 (SHC2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    106834253 (SHC2)
 09160 Human Diseases
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    106834253 (SHC2)
   05226 Gastric cancer
    106834253 (SHC2)
   05214 Glioma
    106834253 (SHC2)
   05220 Chronic myeloid leukemia
    106834253 (SHC2)
   05224 Breast cancer
    106834253 (SHC2)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    106834253 (SHC2)
  09165 Substance dependence
   05034 Alcoholism
    106834253 (SHC2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    106834253 (SHC2)
   01522 Endocrine resistance
    106834253 (SHC2)
SSDB
Motif
Pfam: PID SH2 DUF7063 DUF7145
Other DBs
NCBI-GeneID: 106834253
NCBI-ProteinID: XP_044608960
LinkDB
Position
20:complement(123034..145895)
AA seq 578 aa
MTQGPGGRAPPEPPAAPEPEAPTTFCALLPRMPQWKFAAPXGFLGRGPAAARAAGGAGAA
DPQPEPAGPASVPALAAAVLGACEPRCAAPCPLLPALSRCRAPGSRGPRGARGAAGPPDA
AADEWIRKGSFIHKPAHGWLHPDARVLGPGVSYIVRYMGCIEVLRSMRSLDFNTRTQVTR
EAINRLHEVVPGVRGSWKKKAPNKALASILGKSNLRFAGMSIAVSISIDGLNLSVPATRQ
IIANHHMQSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSVISTVGQAFEL
RFKQYLHSPPTAVVPPERLTGPEESAWGDEEEAEHNYYNSIPGKEPPLGGLVDSRLALTQ
PCALGAPGQGAAPARRDARGLPWDLGPSAPPGDGYVQADARGPRDYEDHLYVNTQGLDAP
EPLQPEDSPKKDLFDMRPFEDALKLHECSVAAAPLPLEDQWPSPPTRRAPIAPTEEQLRQ
EPWYHGQMSRRAAEKLLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVRTK
DVLFESISHLIDYHLQNGQPIVAAESELHLRGVVKREP
NT seq 1737 nt   +upstreamnt  +downstreamnt
atgacgcagggtccgggcgggcgcgcgccccccgagccccccgcggcccccgagcccgag
gcgcccaccaccttctgcgcgctgctgccgcgcatgccgcagtggaagttcgcggccccc
nccggcttcctgggccgcggcccggcggcggcgcgggcggcggggggcgcgggggccgcc
gacccccagcccgagccggccggccccgcgagcgtcccggcgctggcggccgcagtcctg
ggcgcctgcgagccgcgctgcgccgcgccctgcccgctgctgcctgcgctcagccgctgc
cgggccccggggtcgcgcgggccgaggggcgcgcggggggcggccgggcccccagacgcc
gccgccgacgagtggatccgcaaaggcagcttcatccacaagccggcgcacggctggctg
cacccagacgccagggtcctgggccccggggtctcctacatcgtgcggtacatgggctgc
attgaagtcctccgctccatgcgctccctggatttcaacactcgcacccaggtcaccagg
gaagccatcaaccggctccacgaggtggtgcccggcgtccggggctcctggaagaagaag
gctcccaacaaggcgctggcctccatcctgggcaagagcaacctgcgctttgccggcatg
agcatcgccgtcagcatctccatcgacggcctcaacctctcggtgcccgccacgcgccag
atcatcgccaaccaccacatgcagtccatctcctttgcgtcgggtggtgacacggacatg
acagattatgtggcctacgtcgccaaggaccctatcaaccagagagcctgccacatcctg
gagtgctgcgaggggcttgcccagagcgtcatcagcaccgtgggccaggccttcgagctg
cgcttcaagcagtacctgcacagcccgcccacggcggtcgtcccccccgaaaggctgacg
gggcccgaggagtcggcctggggggacgaggaggaggcggagcacaattattacaacagc
atcccggggaaggagccacccctgggcgggctggtggactccaggctcgccctcacgcag
ccctgcgccctcggggccccgggccagggagcagcgcctgctcgaagagacgcccgtggc
ctcccgtgggacctgggcccctcagccccgcccggggacggctacgtgcaagcagacgcc
cggggcccccgagactacgaggaccacctctacgtcaacacgcagggtctggatgccccg
gagcccctgcagccggaggacagccccaagaaggacctgttcgacatgcgacccttcgag
gacgccctgaagctgcacgagtgctctgtggccgcagcccccctccccttggaggaccag
tggcccagccccccgacccgccgggcccccatcgcccccacggaggagcagctgcggcag
gagccctggtaccacggccagatgagccggcgggcggccgagaagctgcttcgagccgac
ggcgacttcctcgtgcgcgacagcgtcaccaaccccgggcagtacgtcctcacgggcatg
cacgcggggcagcccaagcacctgctgctcgtggaccccgagggcgtggtgcggacgaag
gatgtcttgttcgagagcatcagccacctgatcgactaccacctgcagaacgggcagccc
atcgtggccgccgagagtgagctgcacctgcgcggagtggtcaagcgggagccctga

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