Equus asinus (ass): 106838201 Help Entry 106838201         CDS       T04645                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism eai  Equus asinus (ass) Pathway eai04022   cGMP-PKG signaling pathway eai04068   FoxO signaling pathway eai04081   Hormone signaling eai04140   Autophagy - animal eai04152   AMPK signaling pathway eai04211   Longevity regulating pathway eai04213   Longevity regulating pathway - multiple species eai04910   Insulin signaling pathway eai04920   Adipocytokine signaling pathway eai04923   Regulation of lipolysis in adipocytes eai04930   Type II diabetes mellitus eai04931   Insulin resistance eai04932   Non-alcoholic fatty liver disease eai04935   Growth hormone synthesis, secretion and action eai05010   Alzheimer disease eai05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:eai00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     106838201 (IRS2)    04022 cGMP-PKG signaling pathway     106838201 (IRS2)    04152 AMPK signaling pathway     106838201 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     106838201 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     106838201 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     106838201 (IRS2)    04923 Regulation of lipolysis in adipocytes     106838201 (IRS2)    04920 Adipocytokine signaling pathway     106838201 (IRS2)    04935 Growth hormone synthesis, secretion and action     106838201 (IRS2)   09149 Aging    04211 Longevity regulating pathway     106838201 (IRS2)    04213 Longevity regulating pathway - multiple species     106838201 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     106838201 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     106838201 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     106838201 (IRS2)    04932 Non-alcoholic fatty liver disease     106838201 (IRS2)    04931 Insulin resistance     106838201 (IRS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  106838201 NCBI-ProteinID:  XP_044635645 UniProt:  A0A9L0IJD4 LinkDB All DBs Position 11:3637883..3668448 Genome browser AA seq 1337 aa AA seqDB search MASPPLHGPPGPAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGGDEA TATAGGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTK DEYFAVAAENEQEQEGWYRALTDLVSEGRAGAGDAPPAAATAASCSASLPGALGGSAGAA AADDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSV TLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELF EFRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSS CRVRTASEGDGGAAAGTGAAGGRPVSVSGSPLSPGPVRAPLSRSHTLSGGCGGRAGKVTL APAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPHLQHPLHLPAG QRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGGEL YGYMTMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYT LMRATFSGSSGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGTDDGYMPMTPG VALMGGGSGSCKSDDYMPMSPTSVSAPKQILQPRAAAAALPPTGAAAPAPASAAGRAFPV NGGSYKASSPAESSPEDSGYMRMWCGSKLSMENADSKLLPNGDYLNMSPSDAGPSGTPPD FFSAALHSSGETLRGVPGYCYSSLPRSYKAPYTCDGDHDQYVLMSSPVGRILEEERLEPQ ASPGTTPSASAFATGAGGGGHTQPPHPVVPSPGRPSGGGSGRPEGFLNQRCRAVRPTRLS LEGLPTLPSMHEYPLPPEPKSPGEYINIDFGESGARLSPPAPPLLASAASSSSLLSASSP ASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGTQSGDPVGSLDALLSPEVSSPY PPLPPRPVAPSSSLQPLAPPPPPPGELYRLPPASTSQGPGAASSSSSETGDNGDYTEMAF GVAATPPQPIAAPPKPEGARVTSPTSGVKRLSLMDQVSGVEAFLQASQPPDPHRGAKVIR ADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGGGSILGGG DEPPASPRQLQPPVPQQARPWTPSQPGGLVGCPGGTGSPMRRETSAGFQNGLNYIAIDVR DEPPPQQHPQHPQHPQPGDKSAWGRTRSLGGLISAVGGSSTGGVCGGPGPGALPSANTYA SIDFLSHHLKEATVVKE NT seq 4014 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgctgcacgggccccccgggccagcgggcggcgacggccccaacctc aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcaa aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcgcgggcggcgacgaggcg acggcgacagcgggcggggggccggcgccgcagccgccgcggctcgagtactacgagagc gagaagaagtggcggagcaaggcgggcgccccgaagcgggtcatcgcgctcgactgctgc ctgaacatcaacaagcgcgccgacgccaaacacaagtacctgatcgccctctacaccaag gacgagtacttcgccgtggcggccgagaacgagcaggagcaggagggctggtaccgcgcg ctcaccgacctggtcagcgagggccgcgcgggcgccggcgacgcgccccccgccgccgcc accgccgcgtcctgcagcgcctccctgcccggcgccctgggcggctcggccggcgccgcc gcggccgatgacagctacgggctggtggcgcccgccacggccgcctaccgcgaggtgtgg caggtgaacctcaagcccaagggcttgggccagagcaagaacctgacgggcgtgtaccgc ctgtgcctgtcggcgcgcactatcggcttcgtgaagctcaactgcgagcagccgtcggtg acgctgcagctcatgaacatccgccgctgcggccactcggacagcttcttcttcatcgag gtgggccgctcggccgtcacgggccccggcgagctgtggatgcaggccgacgactcggtg gtggcgcagaacatccacgagaccatcctggaggccatgaaggcgctcaaggagctcttc gagttccggccgcgcagcaagagccagtcgtcgggctcgtcggccacgcaccccatcagc gtccccggagcgcgccgccaccaccacctggtcaacctgccccccagccagacgggcctg gtgcgccgctcgcgcaccgacagcctggccgccaccccgccggccgccaagtgcagttcc tgtcgggtgcgcacagccagcgagggcgacggcggcgcggcggcggggaccggggcggcg ggcggcaggcccgtgtcggtgtcggggagccccctgagccccgggccggtgcgcgcgccg ctgagccgctcgcacaccctgagcggcggctgcggcggccgcgcgggcaaggtgacgctg gcgccggcagggggcgccctgcaacacagccgctccatgtccatgcccgtggcgcactcg cccccggccgccaccagccccggcagcctgtcgtccagcagcgggcacggctctggctcc tacccgccgcctccgggcccgcacccgcacctgcagcaccccctgcatctccccgcgggc cagagaccctccagcggcagcgcctcggcttcgggctcccccagcgaccccggcttcatg tccctggacgagtacggctccagccctggggacctgagagccttctgcagccaccggagc aacacgccggagtccatcgccgagacccccccggccagggacggcagcgggggggagctg tacgggtacatgaccatggacaggcccctgagccactgtggtcgtccctaccgccgagtc tcaggggacggggcccaggacttggacagagggctgaggaagaggacttactccctgacg acacctgctcggcagcggccggtgccccagccctcctccgcgtccctggatgaatacacc cttatgcgggccaccttctccggcagctccggccgactctgcccgtcctgccccgcgtcc tctcccaaagtggcttaccacccctatcccgaggactatggcgacatcgaaattgggtcc cataggagctccagcagtaacctgggcacggacgatggctacatgcccatgacccctggc gtggctctcatggggggtggcagtggtagctgcaagagtgacgactacatgcccatgagc cccaccagcgtgtctgcccccaagcagatcctgcagcctcgcgctgccgccgccgccttg ccccccacgggagctgcggcgcctgcgcccgcctccgcggccggcagggcctttccagtg aacggtggcagctacaaggccagctccccggccgagagctcccccgaggacagtgggtac atgcgcatgtggtgtggctccaagctgtccatggagaacgccgacagcaagctgcttccc aacggggactacctcaacatgtcccccagcgacgcgggcccctcggggaccccgcccgac ttcttctccgcagccttgcacagcagcggggagacgctcaggggcgtccctggctactgc tacagctccctgcctcgctcctacaaggctccctacacctgcgacggggaccacgaccag tacgtgctcatgagctcccccgtggggcgcatcctggaagaggagcgactggagccgcag gccagcccggggaccacgccgtcggccagcgccttcgccaccggggccggtgggggcggc cacacgcagcctcctcacccagtagtgccttcgcccgggaggccgagtggcggcggcagt ggccgcccggagggcttcctgaaccagcgctgccgggcagtgcggcccacgcgcctgtcc ctggagggccttccgaccctgcccagcatgcacgagtaccctctgccgcccgagcccaag agccccggcgagtacatcaacatcgacttcggcgagtcaggagcgcgcctgtcgccgccg gcccctccgctgctcgcctcggcggcctcgtcctcctcgctgctgtccgccagcagccca gcctcgtccctgggctcgggcaccccgggcacgagcagcgacagccggcagcgctccccg ctctccgactacatgaacctcgacttcagctcgcccaagtctcccaagccgggtacccag agcggggaccctgtgggctccttggatgccctcctgtcccccgaggtctcgtccccgtac ccaccgctgcccccgcgccctgtcgccccctcctcctccctgcagccgctggccccccct ccgccacccccaggggagctgtaccgcctgcctccagcatccacctcccagggccccggc gccgcctcctcatcgtcctcggagactggggacaatggtgactacaccgagatggccttt ggcgtggctgccaccccgccacaacccatcgcggccccccccaagccagaaggtgcccgc gtgaccagccccacgtccggcgtgaagaggctgagtctcatggatcaggtgtcgggggtc gaggccttccttcaggccagccagcccccagacccgcaccgaggggccaaggtcatccgc gcagacccgcaggggggccgccgccgccacagctccgagaccttctcctcgaccaccact gtgacccccgtgtccccgtccttcgcccacaacccgaagcgccataactcggcctctgtg gaaaatgtttctctcaggaaaagcagtgaagggggcggcggcagcatcctcggtggggga gatgagccccctgcgtccccccgccagttgcagccaccggtcccccagcaggcgcggccg tggacaccgagtcagcctggtggcttggttggctgccccggcggcactggctctccaatg cgcagggagacctctgccggcttccagaacggcctcaactacatcgccatcgacgtgagg gacgagccgcccccgcagcagcatccgcagcatccacagcatccgcagccgggagacaaa agcgcctggggccggacccggagccttgggggtctcatcagcgccgtggggggcagcagc acgggcggggtgtgtggggggccgggccctggtgccctgccatccgccaacacctatgcc agcattgacttcttgtcgcatcacctgaaggaggccacggttgtgaaagagtga

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