KEGG   Equus asinus (ass): 106841189
Entry
106841189         CDS       T04645                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
eai  Equus asinus (ass)
Pathway
eai00670  One carbon pool by folate
eai00790  Folate biosynthesis
eai01100  Metabolic pathways
eai01240  Biosynthesis of cofactors
eai01523  Antifolate resistance
eai04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:eai00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    106841189 (DHFR)
   00670 One carbon pool by folate
    106841189 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    106841189 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    106841189 (DHFR)
Enzymes [BR:eai01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     106841189 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 106841189
NCBI-ProteinID: XP_014712505
UniProt: A0A8C4L660
LinkDB
Position
9:55895901..55926441
AA seq 187 aa
MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTASSVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINLVLSRELKEPPQGAHFLAKSLDDALSLLEQPELANKVDMVWIVGGSS
VYKEAMNKPGHLRLFVTRIMQEFESDTFFPEIDFEKYKLLPEYPGVLSDIQEEKGIKYKF
EVYEKND
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgtccgctaaattgcatcgtcgccgtgtcgcagaatatgggcatcggcaagaac
ggggacctgccgtggcccccactcaggaatgaattcaagtatttccaaagaatgaccaca
gcctcttcagtagaaggtaagcagaatttggtgattatgggtaggaagacctggttctcc
atccctgagaagaatcggccgttaaaggacagaattaatttagttctcagtagagaactc
aaggaacctccacaaggagctcattttcttgccaaaagtttggatgatgccttatcactt
cttgagcaaccagaattagcaaataaagtggacatggtttggatagtgggaggcagttct
gtttataaggaagccatgaacaagccaggccatcttagactgtttgtgacaaggatcatg
caggaatttgaaagtgacacattttttccagaaattgattttgaaaaatataaacttctc
ccagaatacccaggtgttctttctgatatccaggaggaaaaaggcattaagtacaaattt
gaagtatatgaaaagaatgattaa

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