KEGG   PATHWAY: eas00740
Entry
eas00740                    Pathway                                
Name
Riboflavin metabolism - Enterobacter soli
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
eas00740  Riboflavin metabolism
eas00740

Module
eas_M00125  Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:eas00740]
Other DBs
GO: 0006771
Organism
Enterobacter soli [GN:eas]
Gene
Entas_2362  GTP cyclohydrolase-2 [KO:K01497] [EC:3.5.4.25]
Entas_0915  riboflavin biosynthesis protein RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
Entas_1330  Cof-like hydrolase [KO:K20861] [EC:3.1.3.102 3.1.3.104]
Entas_4263  HAD-superfamily hydrolase, subfamily IA, variant 1 [KO:K20862] [EC:3.1.3.102 3.1.3.104]
Entas_3724  3,4-dihydroxy-2-butanone 4-phosphate synthase [KO:K02858] [EC:4.1.99.12]
Entas_0916  6,7-dimethyl-8-ribityllumazine synthase [KO:K00794] [EC:2.5.1.78]
Entas_1806  riboflavin synthase, alpha subunit [KO:K00793] [EC:2.5.1.9]
Entas_0633  riboflavin biosynthesis protein RibF [KO:K11753] [EC:2.7.1.26 2.7.7.2]
Entas_0294  HAD superfamily (subfamily IIIB) phosphatase, TIGR01672 [KO:K03788] [EC:3.1.3.2]
Entas_0527  4-hydroxyphenylacetate 3-monooxygenase, reductase subunit [KO:K00484] [EC:1.5.1.36]
Entas_4234  oxidoreductase FAD/NAD(P)-binding domain protein [KO:K05368] [EC:1.5.1.41]
Entas_1449  FMN reductase [KO:K00299] [EC:1.5.1.38]
Entas_2871  Hydroxyethylthiazole kinase [KO:K00878] [EC:2.7.1.50]
Entas_3714  nucleoside diphosphate pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Entas_1668  NUDIX hydrolase [KO:K12152] [EC:3.6.1.-]
Entas_3565  3-octaprenyl-4-hydroxybenzoate carboxy-lyase [KO:K03186] [EC:2.5.1.129]
Entas_3032  3-octaprenyl-4-hydroxybenzoate carboxy-lyase [KO:K03186] [EC:2.5.1.129]
Entas_3457  3-octaprenyl-4-hydroxybenzoate carboxy-lyase [KO:K03186] [EC:2.5.1.129]
Entas_1524  3-octaprenyl-4-hydroxybenzoate carboxy-lyase [KO:K03186] [EC:2.5.1.129]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
eas00030  Pentose phosphate pathway
eas00040  Pentose and glucuronate interconversions
eas00230  Purine metabolism
eas00860  Porphyrin metabolism
eas00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   
LinkDB

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