KEGG   Enterobacteriaceae bacterium ENNIH2: C2U52_06560
Entry
C2U52_06560       CDS       T05417                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
ebc  Enterobacteriaceae bacterium ENNIH2
Pathway
ebc00270  Cysteine and methionine metabolism
ebc00450  Selenocompound metabolism
ebc00670  One carbon pool by folate
ebc01100  Metabolic pathways
ebc01110  Biosynthesis of secondary metabolites
ebc01230  Biosynthesis of amino acids
ebc04980  Cobalamin transport and metabolism
ebc04981  Folate transport and metabolism
Module
ebc_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:ebc00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    C2U52_06560
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    C2U52_06560
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    C2U52_06560
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    C2U52_06560
   04980 Cobalamin transport and metabolism
    C2U52_06560
Enzymes [BR:ebc01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     C2U52_06560
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AUV05975
LinkDB
Position
complement(945872..949555)
AA seq 1227 aa
MSSKVEQLQQQLKERILVLDGGMGTMIQNQRLSEQDFRGERFADWPCDLKGNNDLLVITK
PEVIAAIHSAYFEAGADIIETNTFNSTTIAMADYQMESLSAEINFAAAKLARACADEWTA
RTPDKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVTAYRESTKALVEGGSDLILI
ETVFDTLNAKAAIFAVKEELEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHADA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAAQIREWAE
SGFLNVVGGCCGTTPEHIKAMSDAVAGLPPRKLPDIPVACRLAGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYNEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVDAFIHHAKKVRRYGAAV
VVMAFDEVGQADTRERKIEICRRAYNILTNEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDSTERLLDLAEKYRGSKTDDTANAQQAEWRSWDVK
KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPTDKILKTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVASLLSDSQRDEFVARTRKEYETVRIQHGRKKPR
TPPVTLEAARENDLAFDWESYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEIVGEEAKRLFQDANDMLDMLSREKSLNPRGVVGLFPANRVGDDVEIYRDETRT
QVLAVSRHLRQQTEKVGFANYCLADFVAPKLSGKEDYIGAFAVTGGLEEDALAEAYDAQH
DDYNKIMIKAVADRLAEAFAEYLHERVRKVYWGYAANENLSNEELIRENYQGIRPAPGYP
ACPEHTEKGTIWQLLDVETHTGMKLTESFAMWPGASVSGWYFSHPDSKYFAVAQIQRDQV
ADYALRKGMSVAEVERWLAPNLGYDAD
NT seq 3684 nt   +upstreamnt  +downstreamnt
gtgagcagcaaagttgagcaactgcagcagcagttaaaagaacgaattttggttctggac
gggggcatgggcaccatgatccagaatcagcgtctcagtgagcaggatttccgcggcgag
cgattcgccgactggccctgcgacctcaagggtaacaatgatctgctggtgattacaaag
ccagaggtgattgccgctatccattccgcctattttgaagcgggtgcggatatcattgag
accaacacctttaactccaccactatcgcgatggcggattaccagatggaatccctgtcg
gcggagatcaactttgcggcggccaaactcgcccgcgcgtgtgccgatgaatggactgcc
cgcacgccggacaaaccgcgttatgttgccggtgttcttggcccaaccaatcgcaccgcc
tctatctcgccggacgttaacgaccccgcgtttcgtaatatcactttcgaccaactggtg
accgcctatcgcgagtcgaccaaagcgctggtggaagggggtagcgacctgatcctgatc
gaaacggtgttcgacaccctgaacgccaaagccgccattttcgcggtgaaagaagagctg
gaggcgctgggcgtcgatctgccgatcatgatttctggcaccattaccgatgcttccggg
cgtacgctttccgggcaaactacagaagccttctataactcattgcgccacgccgatgcg
ctcaccttcggcctgaactgcgcactggggccagatgaattgcgccagtatgtgcaggaa
ctctcgcgcattgccgaatgctacgtgaccgcgcacccgaacgccgggttgccaaacgcc
tttggcgaatacgatctcgacgccgacaccatggcggcacaaattcgcgaatgggcagag
tccggcttcctgaacgtggtcggcgggtgttgcggcaccacgccggaacacattaaagcg
atgagcgatgccgtcgccggtctgccaccgcgcaaactgccggacattcccgtcgcctgc
cgtctggcgggcctggagccgctgaatattggcgatgacagcctgtttgtgaacgtgggt
gaacgcaccaacgtcaccggttcggcgaaattcaaacgcctgatcaaagaagagaagtac
aacgaagcgctggacgtggcgcgtcagcaggtggaaagcggcgcgcaaatcatcgatatc
aatatggatgaggggatgctcgacgccgaagcggcgatggtgcgtttcctcaacctgatt
gccggtgaaccggacatcgcccgcgtaccgattatgatcgactcctcaaaatgggaggtg
atcgagaaagggctgaaatgcattcagggtaaaggcatcgttaactccatctcaatgaaa
gagggcgttgacgcgtttatccatcatgcgaaaaaggtacgccgttacggtgccgccgta
gtggtgatggcctttgatgaagtagggcaggcggatacccgcgagcgcaaaatcgaaatt
tgccgccgggcgtacaacatcctgaccaacgaagtgggcttcccgccggaagacattatt
ttcgacccgaatatctttgcggtcgccaccgggatcgaagagcacaacaactatgcgcag
gactttatcggcgcctgcgaagacatcaaacgcgaactaccccatgcgctgatctccggc
ggcgtctccaacgtctcgttctcgtttcgcggtaatgacccggtacgtgaggcgatccac
gcggtcttcctctattacgctatccgtaatggcatggatatggggatcgtcaacgccggg
caactggcgatttacgacgacctgccggcagaactgcgtgatgcggtggaagatgtgatt
ctgaaccgccgcgatgacagcacagaacgcttgctggatctggcagaaaaataccgtggc
agcaaaaccgatgataccgccaacgcccagcaggcggaatggcggagctgggacgtgaaa
aagcgtctggaatattcgctggttaaaggtattactgagtttatcgaacaggacaccgaa
gaggcccgccagcaggccgctcgcccgattgaggtgattgaagggccgctaatggatggc
atgaacgtggtcggcgacctgttcggcgaaggcaaaatgttcctgccgcaggtggtgaaa
tccgcccgtgttatgaaacaggctgtggcctaccttgagccgtttatcgaagccagcaaa
gagaaaggctccagcaacggcaaaatggtcatcgccaccgtgaaaggcgacgtccacgac
atcggcaaaaatattgtcggcgtggtattgcagtgtaacaactacgaaatcgtcgatctc
ggcgtgatggtgccgacggacaaaattctcaaaactgcccgtgaagtgaacgccgacctg
attggcctgtctggccttatcaccccgtcgctggatgaaatggtcaacgtagcgaaagaa
atggagcgccagggcttcacgatcccgctgctgattggcggcgcgaccacctcaaaagcg
catacggcggtgaaaatcgagcagaactacagcggcccgacggtctatgtgcaaaacgcc
tcgcgcaccgtaggtgtggtggcctcgctgctgtctgatagccagcgcgatgagtttgtg
gcccgcacccgtaaagagtacgaaaccgtgcgtattcagcatggccgtaagaagccacgt
acgccacccgtgacgctggaggccgcccgtgaaaacgatctggccttcgactgggagagc
tacaccccgccggtggcccatcgcctgggcgtacaggaagtggaagccagcatcgaaacc
ctgcgtaactacatcgactggacgccgttctttatgacctggtcgctggctggcaagtat
ccgcgcattctcgaagatgaaatcgtcggggaagaggctaagcgcctgttccaggacgcc
aacgatatgctggatatgttaagccgtgagaagagcctgaacccacgtggtgtggtgggt
ttgttcccggcgaaccgcgtaggcgacgatgttgagatctatcgcgatgaaacccgcact
caggtgctcgcggtaagccgtcatctgcgtcagcaaaccgagaaagtgggtttcgctaac
tactgtctggccgattttgtcgcgccgaagttgagcggcaaagaagattacatcggcgcg
tttgccgttaccggtggtcttgaggaagacgcgctggcagaggcgtacgacgcgcagcat
gatgattacaacaaaatcatgataaaagccgtggcagaccgtctggcggaagccttcgcc
gaatatctgcatgagcgcgtacgtaaggtctattggggctatgcggccaacgagaacctc
agtaacgaagagctgatccgcgaaaattatcaggggatccgcccggcaccgggatacccg
gcctgcccggagcatacggaaaaaggcacgatctggcagctactggatgtggaaacccac
accggtatgaaactgacggaatccttcgccatgtggccgggcgcctcggtctccggctgg
tactttagccaccctgacagcaagtatttcgccgtggcgcagattcagcgcgaccaggtg
gcggactacgcattgcgtaagggaatgagcgtggcggaagtggaacgctggctggcgccg
aatctgggctatgacgcggactaa

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