Escherichia coli BL21(DE3): B21_00112
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Entry
B21_00112 CDS
T02096
Symbol
aceE
Name
(GenBank) E1p component of pyruvate dehydrogenase complex, subunit of pyruvate dehydrogenase and pyruvate dehydrogenase multienzyme complex
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
ebe
Escherichia coli BL21(DE3)
Pathway
ebe00010
Glycolysis / Gluconeogenesis
ebe00020
Citrate cycle (TCA cycle)
ebe00620
Pyruvate metabolism
ebe00785
Lipoic acid metabolism
ebe01100
Metabolic pathways
ebe01110
Biosynthesis of secondary metabolites
ebe01120
Microbial metabolism in diverse environments
ebe01200
Carbon metabolism
ebe01210
2-Oxocarboxylic acid metabolism
Module
ebe_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ebe00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
B21_00112 (aceE)
00020 Citrate cycle (TCA cycle)
B21_00112 (aceE)
00620 Pyruvate metabolism
B21_00112 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
B21_00112 (aceE)
Enzymes [BR:
ebe01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
B21_00112 (aceE)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
PFO_beta_C
Motif
Other DBs
NCBI-ProteinID:
CAQ30629
UniProt:
A0A140NDL0
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Position
125822..128485
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AA seq
887 aa
AA seq
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MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVNVAAGTGISNY
INTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYDV
CFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQEQLDNFRQEVHGNGLSSYPH
PKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFEGAGWNVIKVMWGSRWD
ELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWAL
NRGGHDPKKIYAAFKKAQETKGKATVILAHTIKGYGMGDAAEGKNIAHQVKKMNMDGVRH
IRDRFNVPVSDTDIEKLPYITFPEGSEEHTYLHAQRQKLHGYLPSRQPNFTEKLELPSLQ
DFGALLEEQSKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGCSWLAAATSYSTNNLPMIPFYIYY
SMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PAYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETI
EGSKGKVQLLGSGSILRHVREAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHP
LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIDKKVVADAIAKFNIDADKVNPRLA
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaacgtttcccaaatgacgtggatccgatcgaaactcgcgactggctccaggcg
atcgaatcggtcatccgtgaagaaggtgttgagcgtgctcagtatctgatcgaccaactg
cttgctgaagcccgcaaaggcggtgtaaacgtagccgcaggcacaggtatcagcaactac
atcaacaccatccccgttgaagaacaaccggagtatccgggtaatctggaactggaacgc
cgtattcgttcagctatccgctggaacgccatcatgacggtgctgcgtgcgtcgaaaaaa
gacctcgaactgggcggccatatggcgtccttccagtcttccgcaaccatttatgatgtg
tgctttaaccacttcttccgtgcacgcaacgagcaggatggcggcgacctggtttacttc
cagggccacatctccccgggcgtgtacgctcgtgctttcctggaaggtcgtctgactcag
gagcagctggataacttccgtcaggaagttcacggcaatggcctctcttcctatccgcac
ccgaaactgatgccggaattctggcagttcccgaccgtatctatgggtctggggccgatt
ggtgctatttaccaggctaaattcctgaaatatctggaacaccgtggcctgaaagatacc
tctaaacagaccgtttacgcgttcctcggcgacggtgaaatggacgaaccggaatccaaa
ggtgcgatcaccatcgctacccgtgaaaaactggataacctggtcttcgttatcaactgt
aacctgcagcgtcttgacggcccggtcaccggtaacggcaagatcatcaacgaactggaa
ggcatcttcgaaggtgctggctggaacgtgatcaaagtgatgtggggtagccgttgggat
gaactgctgcgtaaagataccagcggtaaactgatccagctgatgaacgaaaccgttgac
ggcgactaccagaccttcaaatcgaaagatggtgcgtacgttcgtgaacacttcttcggt
aaatatcctgaaaccgcagcactggttgcagactggactgacgagcagatctgggcactg
aaccgtggtggtcacgatccgaagaaaatctacgctgcattcaagaaagcgcaggaaacc
aaaggcaaagcgacagtaatccttgctcataccattaaaggttacggcatgggcgacgcg
gctgaaggtaaaaacatcgcgcaccaggttaagaaaatgaacatggacggcgtgcgtcac
atccgcgaccgtttcaatgtgccggtgtctgatacagatatcgaaaaactgccgtacatc
accttcccggaaggttctgaagagcatacctatctgcacgctcagcgtcagaaactgcac
ggttatctgccaagccgtcagccgaacttcaccgagaagcttgagctgccgagcctgcaa
gacttcggcgcgctgttggaagagcagagcaaagagatctctaccactatcgctttcgtt
cgtgctctgaacgtgatgctgaagaacaagtcgatcaaagatcgtctggtaccgatcatc
gccgacgaagcgcgtactttcggtatggaaggtctgttccgtcagattggtatttacagc
ccgaacggtcagcagtacaccccgcaggaccgcgagcaggttgcttactataaagaagac
gagaaaggtcagattctgcaggaagggatcaacgagctgggcgcaggttgttcctggctg
gcagcggcgacctcttacagcaccaacaatctgccgatgatcccgttctacatctattac
tcgatgttcggcttccagcgtattggcgatctgtgctgggcggctggcgaccagcaagcg
cgtggcttcctgatcggcggtacttccggtcgtaccaccctgaacggcgaaggtctgcag
cacgaagatggtcacagccacattcagtcgctgactatcccgaactgtatctcttacgac
ccggcttacgcttacgaagttgctgtcatcatgcatgacggtctggagcgtatgtacggt
gaaaaacaagagaacgtttactactacatcactacgctgaacgaaaactaccacatgccg
gcaatgccggaaggtgctgaggaaggtatccgtaaaggtatctacaaactcgaaactatt
gaaggtagcaaaggtaaagttcagctgctcggctccggttctatcctgcgtcacgtccgt
gaagcagctgagatcctggcgaaagattacggcgtaggttctgacgtttatagcgtgacc
tccttcaccgagctggcgcgtgatggtcaggattgtgaacgctggaacatgctgcacccg
ctggaaactccgcgcgttccgtatatcgctcaggtgatgaacgacgctccggcagtggca
tctaccgactatatgaaactgttcgctgagcaggtccgtacttacgtaccggctgacgac
taccgcgtactgggtactgatggcttcggtcgttccgacagccgtgagaacctgcgtcac
cacttcgaagttgatgcttcttatgtcgtggttgcggcgctgggcgaactggctaaacgt
ggcgaaatcgataagaaagtggttgctgacgcaatcgccaaattcaacatcgatgcagat
aaagttaacccgcgtctggcgtaa
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