Erwinia billingiae: EbC_02880
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Entry
EbC_02880 CDS
T01270
Symbol
metH
Name
(GenBank) Methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
ebi
Erwinia billingiae
Pathway
ebi00270
Cysteine and methionine metabolism
ebi00450
Selenocompound metabolism
ebi00670
One carbon pool by folate
ebi01100
Metabolic pathways
ebi01110
Biosynthesis of secondary metabolites
ebi01230
Biosynthesis of amino acids
ebi04981
Folate transport and metabolism
Module
ebi_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
ebi00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
EbC_02880 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
EbC_02880 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
EbC_02880 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
EbC_02880 (metH)
04980 Cobalamin transport and metabolism
EbC_02880 (metH)
Enzymes [BR:
ebi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
EbC_02880 (metH)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
CAX57819
UniProt:
D8MLT5
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Position
342977..346660
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AA seq
1227 aa
AA seq
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MSNRIEALQQQLAKRIMLLDGGMGTMIQSYKLDEADFRGQRFADWQSDLKGNNDLLVLTR
PDIISEIHHAYLEAGADILETNTFNSTTIAMADYHMASLSAEINFAAAKLARAAADEWTA
RTPDRPRYVAGVLGPTNRTCSISPDVNDPAFRNVTFIQLVDAYRESTRALVEGGCDIIMI
ETVFDTLNAKAAIFAVESEFEALGITLPLMISGTITDASGRTLSGQTTEAFYNSLRHARP
LSFGLNCALGPDELRQYVAELSRIAEGYVTAHPNAGLPNAFGEYDLDAKIMAEQIGEWAQ
SGFLNIVGGCCGTTPEHIAAMAKVIEGVAPRALPELPVACRLAGLEPLTISADSLFVNVG
ERTNVTGSAKFKRLIKEDKYNEALEVALQQVQSGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWEVIEKGLQCIQGKGIVNSISMKEGVDAFKHHARLVRRYGAAM
VVMAFDEIGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAM
DFIGACEDIKRELPHAMISGGVSNVSFSFRGNEPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLDEDLRHAVEDVVLNRTDQGTERLLEIAEKYRGTKSDEGSTKPQAEWRNWEVE
KRLEYSLVKGITEFIEEDTEAARQNASRPIEVIEGPLMAGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPYIEASKEKGSTNGKIVLATVKGDVHDIGKNIVGVVLQCNNYEIIDL
GVMVPSDKILKTAREHNADIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGATTSKA
HTAVKIEQNYSGPVVYVQNASRTVGVVSALLSAAQRDDFVARTRKEYDTVRIQHGRKKPR
TPPVSLQVARDNDLPFDWATYTPPVAHRLGVSEVSANIETLRHYIDWTPFFMTWSLAGKY
PRILEDEVVGEEARRLLADANAMLDDLSANKSLNPRGVVGIFPANRVDDDIEIYEDESRS
HVLQVSHHLRQQTEKTGFPNYCLADFVAPKSSGKADYLGAFAVTGGLEEDALADAFDAQH
DDYNKIMVKALSDRLAEGFAEYLHERVRKVIWGFAATENLSNEELIRENYQGIRPAPGYP
ACPEHTEKETIWKLLDVEKHTGMKLTESFAMWPGAAVSGWYFSHPDSKYFAVAQLQRDQI
EDYARRKGMAVSEVERWLAPNLGYDAD
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcaacagaattgaagcactgcagcagcagctggcgaaacgtatcatgctgcttgat
ggcggcatgggcaccatgatccagagttataagctggacgaggccgattttcgcggtcag
cgttttgccgactggcaaagcgatcttaaaggaaacaatgacctgctggtgctgacccgt
ccggacattatcagcgagatccaccacgcttatctggaagcgggtgccgatattctggaa
accaacaccttcaactccaccaccatcgccatggcggattaccatatggcgtcgctgtcg
gcagaaattaactttgccgccgccaaactggcacgcgccgccgccgatgaatggaccgcg
cgcacgccggatcgcccgcgctacgtggcgggcgtgctcggcccgaccaaccgcacctgc
tcaatatcgcccgacgtcaacgatcctgctttccgcaacgtgaccttcattcagctggtg
gacgcctaccgcgaatccacccgcgcgctggtggaaggcggttgcgacatcatcatgatc
gaaaccgttttcgacaccctgaatgccaaagccgccatctttgccgtcgaaagcgaattt
gaagcgctgggcattacgctgccgctgatgatttccggcaccattaccgatgcgtctggt
cgtacgctgtctggccagacgacggaagcgttctataactcactgcgccatgccaggccg
ctctcctttggcctgaactgcgcgctgggcccggacgagctgcgccagtacgtggctgaa
ctttcgcgcatagccgaaggctacgtcactgcccaccctaacgccggtttgccaaatgcc
ttcggtgaatacgatctggatgcgaagattatggcggagcagatcggcgaatgggcgcag
tcaggcttcctgaacattgtcggcggctgctgtggcaccacgcctgagcatattgcggcg
atggcgaaagtgattgaaggcgttgcgccgcgtgcgctgcctgagctgccggtcgcctgt
cgcctggcgggccttgagccgctgaccatcagcgccgactcgctgtttgtgaacgtcggc
gaacgcaccaacgtcaccggctcagccaaattcaagcgtctgattaaagaagataaatat
aacgaagcgctggaagttgcgctgcagcaggtacaaagcggcgcgcagattatcgatatc
aatatggacgaagggatgctggatgcggaagcggcgatggtgcgcttcctcaatctgatc
gccggcgagccggatattgcccgcgtgccgatcatgatcgactcctcaaaatgggaggtg
attgaaaaaggcctgcagtgcatccagggcaagggcatcgttaactcgatctcgatgaaa
gagggcgtcgacgcctttaagcatcacgccaggctggtacgccgttacggtgccgcgatg
gtggtgatggcctttgatgaaatcggtcaggcagacacccgtgaacgtaaaatcgagatc
tgccgtcgggcctacaaaatcctgaccgaagaggtcggattcccgccagaagacatcatt
ttcgacccaaatatcttcgcggtagcgaccgggattgaagagcataacaactacgcgatg
gactttattggcgcctgtgaagacatcaaacgcgaactgccgcacgcgatgatttccggc
ggcgtctcgaacgtttccttctccttccgcggcaacgaaccggtgcgtgaagccatccac
gcggtgttcctgtattacgccatccgtaacggtatggatatgggcatcgttaacgccggt
cagctagcgatatacgacgacctggacgaagacctgcgtcatgcggtggaagatgtggtg
ctgaaccgcaccgatcagggaaccgagcgtctgctggagattgccgaaaaataccgtggc
accaaatccgacgaaggcagcaccaaaccgcaggccgaatggcgcaactgggaggttgaa
aaacgccttgagtactcgctggttaagggcatcaccgaatttatcgaagaagataccgaa
gccgcccgccagaatgccagccgcccgatcgaagtgattgaagggccgttaatggccggg
atgaacgtggtcggcgatctgtttggcgaaggcaaaatgttcctgccgcaggtggtgaaa
tcggcccgcgtgatgaagcaggcggtggcctatctcgaaccctatattgaagccagcaaa
gagaagggcagcaccaacggcaagatcgtgctggcgacggtgaagggcgatgtgcatgac
atcggcaaaaacattgtcggcgtggttttgcagtgtaataactatgaaatcatcgacctg
ggcgtaatggtaccgagcgataaaatccttaaaactgcccgcgaacataacgccgacatc
attggcctgtccggtctgatcacgccatcgctggatgaaatggtcaacgtggcgaaagag
atggagcgccagggctttacgctgccgctgctgatcggtggggcgaccacctcgaaagcg
cataccgcggtgaagattgaacagaattacagtggtccggttgtctatgtacaaaatgcc
tcgcgtaccgttggcgtggtgtcggccctgctttccgccgcccagcgcgatgactttgtt
gcgcgcacgcgcaaagagtacgacacggtgcggatccagcatggccgtaagaagccgcgc
acgccgccggtcagcctgcaggttgccagggacaacgatctgccatttgactgggcaacc
tacacgccacccgtagcccacaggctgggtgtaagcgaagtaagtgctaacatcgaaacc
ctgcgacattacatcgactggacgccattctttatgacctggtcgctggcgggtaaatat
ccgcgcattctggaagatgaagtggtcggtgaagaggccagacgcctgttagcggatgcc
aacgcgatgctggatgacctgagcgccaataaatccttaaatccgcgtggcgtggtgggg
attttcccggctaaccgcgtggatgacgatattgaaatctatgaggacgagtcgcgcagc
catgttttgcaagtgagtcatcacttacgtcagcagacagaaaagacgggcttcccgaac
tattgcctcgccgattttgtcgcgccgaagtccagcggtaaggccgattacctgggggcc
tttgccgtcaccggcgggttggaggaagatgcgctggccgacgcgtttgacgcgcaacat
gatgactacaacaaaatcatggtgaaggcgttgtcagaccgtctggccgaagggtttgct
gaatacctgcatgagcgggtgcgtaaggtgatttggggctttgccgccacggaaaacctg
agtaatgaagagctgatccgcgagaactatcagggcatccgtccggcgccgggttatccg
gcctgcccggaacacaccgagaaagagactatctggaagctactggacgtggagaagcat
accggaatgaagctgaccgaatccttcgccatgtggccaggcgcggcggtatcaggctgg
tacttcagccatccggacagtaagtacttcgcggtagcacagctgcagcgcgatcagatt
gaagactacgcccgccgcaaaggcatggcggtcagcgaggttgaacgctggctggcaccg
aatttgggctacgacgcagactaa
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