KEGG   Escherichia coli BL21(DE3): ECD_00052
Entry
ECD_00052         CDS       T00931                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ebl  Escherichia coli BL21(DE3)
Pathway
ebl00670  One carbon pool by folate
ebl00790  Folate biosynthesis
ebl01100  Metabolic pathways
ebl01240  Biosynthesis of cofactors
ebl04981  Folate transport and metabolism
Module
ebl_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:ebl00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    ECD_00052 (folA)
   00670 One carbon pool by folate
    ECD_00052 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    ECD_00052 (folA)
Enzymes [BR:ebl01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     ECD_00052 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: ACT41953
LinkDB
Position
54019..54498
AA seq 159 aa
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNI
ILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE
GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
NT seq 480 nt   +upstreamnt  +downstreamnt
atgatcagtctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatg
ccgtggaacctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccgtg
attatgggccgccatacctgggaatcaatcggtcgtccgttgccaggacgcaaaaatatt
atcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaa
gccatcgcggcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttat
gaacagttcttgccaaaagcgcaaaaactgtatctgacgcatatcgacgcagaagtggaa
ggcgacacccatttcccggattacgagccggatgactgggaatcggtattcagcgaattc
cacgatgctgatgcgcagaactctcacagctattgctttgagattctggagcggcggtaa

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