KEGG   Enterobacter cancerogenus: CWI88_01320
Entry
CWI88_01320       CDS       T05545                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
ecan  Enterobacter cancerogenus
Pathway
ecan00270  Cysteine and methionine metabolism
ecan00450  Selenocompound metabolism
ecan00670  One carbon pool by folate
ecan01100  Metabolic pathways
ecan01110  Biosynthesis of secondary metabolites
ecan01230  Biosynthesis of amino acids
ecan04981  Folate transport and metabolism
Module
ecan_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:ecan00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    CWI88_01320
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    CWI88_01320
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    CWI88_01320
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    CWI88_01320
   04980 Cobalamin transport and metabolism
    CWI88_01320
Enzymes [BR:ecan01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     CWI88_01320
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AUJ79761
LinkDB
Position
267990..271673
AA seq 1227 aa
MSSKVEQLRAQLNERILVLDGGMGTMIQGYRLSEDDFRGERFADWPCDLKGNNDLLVLSK
PQVIADIHNAYFEAGADIVETNTFNSTTIAMADYQMESLSAEINFEAAKLARACADEWTA
RTPDKPRYVAGVLGPTNRTASISPDVNDPAFRNVTFDQLVVAYRESTKALVEGGSDLILI
ETVFDTLNAKAAIYAVKAEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHADA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAAQIREWAE
SGFLNIVGGCCGTTPAHIAAMSNAVAGLPPRKLPELPVACRLSGLEPLTIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWDVIEKGLKCIQGKGIVNSISMKEGVESFIHHAKQVRRYGAAV
VVMAFDEVGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDATERMLDLAEKYRGSKSDEAVNVQQAEWRAWDVK
KRLEYSLVKGITEFIEFDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPYIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIIDL
GVMVPADKILKTAREVNADLIGLSGLITPSLDEMVFVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVSALLSDTQRDEFVARTRKEYETVRIQHGRKKPR
TPPVSLEAARENDLAFDWSAYTPPVAHRLGVQDVTTSIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGEEAKRLFNDANDMLDRLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRT
HVLAVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALAEAFDAQH
DDYNKIMIKAIADRLAEAFAEYLHERVRKVHWGYAANENLSNEELIRENYQGIRPAPGYP
ACPEHTEKGTIWKLLDVEAHTGMKLTESFAMWPGASVSGWYFSHPDSKYFAVAQLQRDQV
EDYALRKGMSVSEVERWLAPNLGYDAD
NT seq 3684 nt   +upstreamnt  +downstreamnt
gtgagcagcaaagtagagcaactgcgtgcgcagttaaatgaacgaattctggtgctggac
ggcggcatgggcaccatgatccagggctatcgcctcagtgaagacgatttccgcggcgaa
cgctttgccgactggccatgcgatctcaaaggcaacaatgacctgctggtgttaagtaaa
ccgcaggtgattgccgatatccacaacgcctactttgaggcgggtgccgatatcgttgaa
accaacacctttaactcgacaaccatcgccatggcggattaccagatggaatccctgtcg
gcggagattaacttcgaggcggcaaaactggcgcgcgcctgcgccgatgaatggaccgcc
cgcacgccggacaaaccgcgctacgttgccggtgtgcttggcccgacgaaccgcaccgcg
tcgatctcaccggacgtgaacgatccggcgtttcgtaatgtcacctttgaccagctggtg
gtcgcctaccgggaatcgaccaaagcgctggtagaaggcgggtccgacctgatcctgatt
gaaacggtattcgacacccttaacgctaaggccgccatctacgcggtgaaagcggagttc
gaggcgctgggcgtggacctgccgatcatgatttccggcaccatcaccgacgcctccggg
cgcacgctctccggccagacgacggaggcgttttacaactctttgcgccacgccgacgcg
ctcaccttcggcctgaactgcgcgctggggccagacgaactgcgccagtatgtgcaggag
ttgtcccgcatcgcggagtgctacgtgaccgcgcacccgaacgccgggctgccaaacgcc
tttggcgaatacgatctggatgccgacaccatggcggcgcaaatccgcgagtgggccgag
tctggcttcctgaacatcgttggcggctgctgcggcaccacgccggcgcacatcgccgcc
atgagtaacgcggtggcagggctaccgccgcgtaagctgcctgagcttccggttgcctgc
cgtctctccggtcttgagccgttaaccatcggcgacgacagcctgtttgtgaacgtgggc
gagcgtactaacgtgaccggttctgcaaagttcaagcggctgattaaagaagagaaatac
agcgaagcgctggacgtggcgcgtcagcaggtggagagcggcgcgcagattatcgatatc
aacatggatgaggggatgctcgacgccgaagcggcgatggtgcgtttcctgaacctgatc
gccggtgagccggacatcgcccgcgtgccgatcatgatcgactcctccaaatgggacgtc
atcgaaaaagggctgaagtgtattcagggcaaaggcatcgttaactcgatttcgatgaaa
gagggcgtcgagagttttatccatcatgcgaagcaggtgcgtcgctacggcgccgccgtg
gtggtgatggcctttgacgaagtcggccaggccgatacccgcgagcgcaaaattgagatc
tgccgccgcgcgtacaaaattttgaccgaagaggtgggcttcccgccggaagacatcatc
ttcgacccgaacattttcgccgtggcaaccggcattgaagaacacaataactacgcgcag
gactttatcggcgcgtgcgaagacatcaaacgcgagctgccgcacgcgctgatctccggc
ggcgtctccaacgtctcgttctcgtttcgcggtaacgacccggtacgcgaggcgatccac
gccgtgttcctttactacgccatccgtaacggaatggacatgggcatcgtcaacgccggg
caactggccatttatgacgacctgcccgccgaactgcgcgacgcggtagaggatgtgatc
cttaaccgtcgcgacgacgctaccgaacgcatgctggatctggccgagaaataccgtggc
agtaaatccgatgaggcggtaaacgttcagcaggccgagtggcgcgcctgggacgtgaaa
aagcgcctggaatattcgctggttaaaggcatcaccgaatttattgaattcgacaccgaa
gaggcccgccagcaggcagcgcgcccgatagaagtgattgagggcccgctgatggacggc
atgaacgtggtcggcgacctgtttggcgaaggcaaaatgttcctgccgcaggtggtgaag
tccgcacgcgtgatgaaacaggcggtggcctaccttgagccgtacatcgaagccagcaaa
gagaaaggctccagcaacggcaagatggtgatcgccaccgtcaagggcgacgtgcacgac
atcggcaagaatatcgtcggcgtggttttgcagtgcaacaactacgagattatcgacctc
ggcgtgatggtcccggcggataaaatcctcaaaaccgcgcgggaagtgaacgccgacctg
attggcctctccgggctgattaccccgtcgctggacgagatggtctttgttgccaaagag
atggagcgtcagggctttactattccgctgctgatcggcggggcgaccacctcaaaagcg
cacacggcggtgaaaatcgaacagaactacagcgggccgacggtgtatgtgcagaacgcc
tcgcgcaccgtgggcgtggtgtccgcgctgctgtccgacacccagcgcgatgagttcgtg
gcgcgtacccgaaaagagtacgaaaccgtgcgcatccagcacgggcgcaagaaaccgcgc
acgccgccagtctcgcttgaggcggcgcgtgaaaacgatctggcattcgactggtcagcc
tatacgccgccggtggcgcatcgtctgggcgtgcaggacgtcactaccagcattgaaacg
ctgcgcaactacatcgactggacgccgttctttatgacctggtcgctggcaggcaaatac
ccgcgcatcctggaagatgaggtggtgggcgaagaggcaaaacgcctgtttaacgatgcc
aacgacatgctcgacaggctgagcgcggagaaaacgctcaacccgcgcggcgtggtgggc
ctgttcccggcgaaccgcgtgggggacgatatcgaaatttatcgcgatgaaacccgcacc
cacgtgctggcggtgagccatcacctgcgccagcaaacggagaaagtgggctttgccaac
tactgcctggcggatttcgtcgcaccgaagttaagcggtaaagccgactatatcggcgcg
tttgccgtgaccggtgggctggaagaggatgcgctggcagaggcgttcgacgcgcagcat
gatgattataataaaatcatgatcaaagcgattgccgaccgtctggcggaagccttcgcc
gaatatctgcacgagcgcgtgcgcaaggtgcactggggctacgcggcgaatgaaaacctc
agcaacgaagagctgatccgcgaaaactatcagggcattcgtccggcaccaggctatcct
gcctgcccggagcacaccgagaaggggacgatctggaaactgctggacgtggaggcgcat
accgggatgaagctcaccgagtccttcgccatgtggccgggcgcgtctgtctccggctgg
tacttcagccatccggacagcaaatactttgcggtggcacagcttcagcgcgatcaggta
gaagactacgccctgcgcaaagggatgagcgtgtcggaagtggagcgctggttagcccct
aatctgggctacgacgcagactga

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