Equus caballus (horse): 100033834 Help Entry 100033834         CDS       T01058                                  Symbol TNF Name (RefSeq) tumor necrosis factor   KO K03156   tumor necrosis factor superfamily, member 2 Organism ecb  Equus caballus (horse) Pathway ecb01523   Antifolate resistance ecb04010   MAPK signaling pathway ecb04060   Cytokine-cytokine receptor interaction ecb04061   Viral protein interaction with cytokine and cytokine receptor ecb04064   NF-kappa B signaling pathway ecb04071   Sphingolipid signaling pathway ecb04150   mTOR signaling pathway ecb04210   Apoptosis ecb04217   Necroptosis ecb04350   TGF-beta signaling pathway ecb04380   Osteoclast differentiation ecb04612   Antigen processing and presentation ecb04620   Toll-like receptor signaling pathway ecb04621   NOD-like receptor signaling pathway ecb04622   RIG-I-like receptor signaling pathway ecb04625   C-type lectin receptor signaling pathway ecb04640   Hematopoietic cell lineage ecb04650   Natural killer cell mediated cytotoxicity ecb04657   IL-17 signaling pathway ecb04660   T cell receptor signaling pathway ecb04664   Fc epsilon RI signaling pathway ecb04668   TNF signaling pathway ecb04920   Adipocytokine signaling pathway ecb04930   Type II diabetes mellitus ecb04931   Insulin resistance ecb04932   Non-alcoholic fatty liver disease ecb04933   AGE-RAGE signaling pathway in diabetic complications ecb04936   Alcoholic liver disease ecb04940   Type I diabetes mellitus ecb05010   Alzheimer disease ecb05014   Amyotrophic lateral sclerosis ecb05020   Prion disease ecb05022   Pathways of neurodegeneration - multiple diseases ecb05132   Salmonella infection ecb05133   Pertussis ecb05134   Legionellosis ecb05135   Yersinia infection ecb05140   Leishmaniasis ecb05142   Chagas disease ecb05143   African trypanosomiasis ecb05144   Malaria ecb05145   Toxoplasmosis ecb05146   Amoebiasis ecb05152   Tuberculosis ecb05160   Hepatitis C ecb05161   Hepatitis B ecb05163   Human cytomegalovirus infection ecb05164   Influenza A ecb05165   Human papillomavirus infection ecb05166   Human T-cell leukemia virus 1 infection ecb05168   Herpes simplex virus 1 infection ecb05169   Epstein-Barr virus infection ecb05170   Human immunodeficiency virus 1 infection ecb05171   Coronavirus disease - COVID-19 ecb05205   Proteoglycans in cancer ecb05310   Asthma ecb05321   Inflammatory bowel disease ecb05322   Systemic lupus erythematosus ecb05323   Rheumatoid arthritis ecb05330   Allograft rejection ecb05332   Graft-versus-host disease ecb05410   Hypertrophic cardiomyopathy ecb05414   Dilated cardiomyopathy ecb05417   Lipid and atherosclerosis ecb05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:ecb00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100033834 (TNF)    04350 TGF-beta signaling pathway     100033834 (TNF)    04064 NF-kappa B signaling pathway     100033834 (TNF)    04668 TNF signaling pathway     100033834 (TNF)    04071 Sphingolipid signaling pathway     100033834 (TNF)    04150 mTOR signaling pathway     100033834 (TNF)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     100033834 (TNF)    04061 Viral protein interaction with cytokine and cytokine receptor     100033834 (TNF)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     100033834 (TNF)    04217 Necroptosis     100033834 (TNF)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     100033834 (TNF)    04620 Toll-like receptor signaling pathway     100033834 (TNF)    04621 NOD-like receptor signaling pathway     100033834 (TNF)    04622 RIG-I-like receptor signaling pathway     100033834 (TNF)    04625 C-type lectin receptor signaling pathway     100033834 (TNF)    04650 Natural killer cell mediated cytotoxicity     100033834 (TNF)    04612 Antigen processing and presentation     100033834 (TNF)    04660 T cell receptor signaling pathway     100033834 (TNF)    04657 IL-17 signaling pathway     100033834 (TNF)    04664 Fc epsilon RI signaling pathway     100033834 (TNF)   09152 Endocrine system    04920 Adipocytokine signaling pathway     100033834 (TNF)   09158 Development and regeneration    04380 Osteoclast differentiation     100033834 (TNF)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     100033834 (TNF)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100033834 (TNF)    05170 Human immunodeficiency virus 1 infection     100033834 (TNF)    05161 Hepatitis B     100033834 (TNF)    05160 Hepatitis C     100033834 (TNF)    05171 Coronavirus disease - COVID-19     100033834 (TNF)    05164 Influenza A     100033834 (TNF)    05168 Herpes simplex virus 1 infection     100033834 (TNF)    05163 Human cytomegalovirus infection     100033834 (TNF)    05169 Epstein-Barr virus infection     100033834 (TNF)    05165 Human papillomavirus infection     100033834 (TNF)   09171 Infectious disease: bacterial    05132 Salmonella infection     100033834 (TNF)    05135 Yersinia infection     100033834 (TNF)    05133 Pertussis     100033834 (TNF)    05134 Legionellosis     100033834 (TNF)    05152 Tuberculosis     100033834 (TNF)   09174 Infectious disease: parasitic    05146 Amoebiasis     100033834 (TNF)    05144 Malaria     100033834 (TNF)    05145 Toxoplasmosis     100033834 (TNF)    05140 Leishmaniasis     100033834 (TNF)    05142 Chagas disease     100033834 (TNF)    05143 African trypanosomiasis     100033834 (TNF)   09163 Immune disease    05310 Asthma     100033834 (TNF)    05322 Systemic lupus erythematosus     100033834 (TNF)    05323 Rheumatoid arthritis     100033834 (TNF)    05321 Inflammatory bowel disease     100033834 (TNF)    05330 Allograft rejection     100033834 (TNF)    05332 Graft-versus-host disease     100033834 (TNF)   09164 Neurodegenerative disease    05010 Alzheimer disease     100033834 (TNF)    05014 Amyotrophic lateral sclerosis     100033834 (TNF)    05020 Prion disease     100033834 (TNF)    05022 Pathways of neurodegeneration - multiple diseases     100033834 (TNF)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100033834 (TNF)    05418 Fluid shear stress and atherosclerosis     100033834 (TNF)    05410 Hypertrophic cardiomyopathy     100033834 (TNF)    05414 Dilated cardiomyopathy     100033834 (TNF)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100033834 (TNF)    04940 Type I diabetes mellitus     100033834 (TNF)    04936 Alcoholic liver disease     100033834 (TNF)    04932 Non-alcoholic fatty liver disease     100033834 (TNF)    04931 Insulin resistance     100033834 (TNF)    04933 AGE-RAGE signaling pathway in diabetic complications     100033834 (TNF)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     100033834 (TNF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:ecb04052]     100033834 (TNF)    00536 Glycosaminoglycan binding proteins [BR:ecb00536]     100033834 (TNF) Cytokines and neuropeptides [BR:ecb04052]  Cytokines   Tumor necrosis fators    100033834 (TNF) Glycosaminoglycan binding proteins [BR:ecb00536]  Heparan sulfate / Heparin   Cytokines    100033834 (TNF) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TNF Motif Other DBs NCBI-GeneID:  100033834 NCBI-ProteinID:  NP_001075288 Ensembl:  ENSECAG00000001174 VGNC:  24357 UniProt:  P29553 B1AB92 LinkDB All DBs Position 20:32223398..32226182 Genome browser AA seq 234 aa AA seqDB search MSTESMIRDVELAEEELAKKAGGPQGSRRCLCLSLFSFLLVAGATTLFCLLHFGVIGPQR EEQLPNAFQSINPLAQTLRSSSRTPSDKPVAHVVANPQAEGQLQWLSGRANALLANGVKL TDNQLVVPLDGLYLIYSQVLFKGQGCPSTHVLLTHTISRLAVSYPSKVNLLSAIKSPCHT ESPEQAEAKPWYEPIYLGGVFQLEKGDQLSAEINQPNYLDFAESGQVYFGIIAL NT seq 705 nt NT seq  +upstreamnt  +downstreamnt atgagcactgaaagcatgatccgagatgtggagctggcagaggaggagctcgccaagaag gcagggggcccccagggctccagacggtgcttgtgcctcagcctcttctccttcctcctt gtcgcaggagccaccacgctcttctgcctgctgcactttggggtgatcggcccccagagg gaagagcagttaccgaatgccttccagtcaatcaaccctctggcccagacactcagatca tcttctcgaaccccaagtgacaagcctgtagcccatgttgtagcaaacccccaagccgag gggcagctccagtggctgagtgggcgtgcaaatgccctcctggccaatggcgtgaagctg acagacaaccagctggtggtaccattggatgggctgtacctcatctactcccaggtcctc ttcaaaggccaaggctgcccttccacccatgtgctcctcacccacaccatcagccgctta gctgtctcctacccgtccaaggtcaacctcctctctgccatcaagagcccttgccacacg gagtccccagagcaggctgaagccaagccctggtatgagcccatctacctgggaggagtc ttccagctggagaagggtgatcaactcagcgctgagatcaatcagcccaactatctcgac tttgcggagtccgggcaggtctactttgggatcattgccctgtga

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