KEGG   Equus caballus (horse): 100033900
Entry
100033900         CDS       T01058                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 precursor
  KO
K13375  transforming growth factor beta-1
Organism
ecb  Equus caballus (horse)
Pathway
ecb04010  MAPK signaling pathway
ecb04060  Cytokine-cytokine receptor interaction
ecb04068  FoxO signaling pathway
ecb04110  Cell cycle
ecb04148  Efferocytosis
ecb04218  Cellular senescence
ecb04350  TGF-beta signaling pathway
ecb04380  Osteoclast differentiation
ecb04390  Hippo signaling pathway
ecb04518  Integrin signaling
ecb04659  Th17 cell differentiation
ecb04672  Intestinal immune network for IgA production
ecb04926  Relaxin signaling pathway
ecb04932  Non-alcoholic fatty liver disease
ecb04933  AGE-RAGE signaling pathway in diabetic complications
ecb05140  Leishmaniasis
ecb05142  Chagas disease
ecb05144  Malaria
ecb05145  Toxoplasmosis
ecb05146  Amoebiasis
ecb05152  Tuberculosis
ecb05161  Hepatitis B
ecb05166  Human T-cell leukemia virus 1 infection
ecb05200  Pathways in cancer
ecb05205  Proteoglycans in cancer
ecb05210  Colorectal cancer
ecb05211  Renal cell carcinoma
ecb05212  Pancreatic cancer
ecb05220  Chronic myeloid leukemia
ecb05225  Hepatocellular carcinoma
ecb05226  Gastric cancer
ecb05321  Inflammatory bowel disease
ecb05323  Rheumatoid arthritis
ecb05410  Hypertrophic cardiomyopathy
ecb05414  Dilated cardiomyopathy
ecb05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100033900 (TGFB1)
   04350 TGF-beta signaling pathway
    100033900 (TGFB1)
   04390 Hippo signaling pathway
    100033900 (TGFB1)
   04068 FoxO signaling pathway
    100033900 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100033900 (TGFB1)
   04518 Integrin signaling
    100033900 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100033900 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    100033900 (TGFB1)
   04218 Cellular senescence
    100033900 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100033900 (TGFB1)
   04672 Intestinal immune network for IgA production
    100033900 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    100033900 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100033900 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100033900 (TGFB1)
   05205 Proteoglycans in cancer
    100033900 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100033900 (TGFB1)
   05212 Pancreatic cancer
    100033900 (TGFB1)
   05225 Hepatocellular carcinoma
    100033900 (TGFB1)
   05226 Gastric cancer
    100033900 (TGFB1)
   05220 Chronic myeloid leukemia
    100033900 (TGFB1)
   05211 Renal cell carcinoma
    100033900 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100033900 (TGFB1)
   05161 Hepatitis B
    100033900 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100033900 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100033900 (TGFB1)
   05144 Malaria
    100033900 (TGFB1)
   05145 Toxoplasmosis
    100033900 (TGFB1)
   05140 Leishmaniasis
    100033900 (TGFB1)
   05142 Chagas disease
    100033900 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    100033900 (TGFB1)
   05321 Inflammatory bowel disease
    100033900 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100033900 (TGFB1)
   05414 Dilated cardiomyopathy
    100033900 (TGFB1)
   05415 Diabetic cardiomyopathy
    100033900 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100033900 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100033900 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:ecb03110]
    100033900 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ecb04052]
    100033900 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:ecb00536]
    100033900 (TGFB1)
Chaperones and folding catalysts [BR:ecb03110]
 Intramolecular chaperones
  Others
   100033900 (TGFB1)
Cytokines and neuropeptides [BR:ecb04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   100033900 (TGFB1)
Glycosaminoglycan binding proteins [BR:ecb00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100033900 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 100033900
NCBI-ProteinID: NP_001075318
Ensembl: ENSECAG00000011671
VGNC: 24051
UniProt: O19011
LinkDB
Position
10:complement(12022520..12036411)
AA seq 390 aa
MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRAQVAGESAETEPEPEADYYAKEVTRVLMVEKENEI
YKTVETGSHSIYMFFNASELRAAVPDPMLLSRAELRLLRLKLSVEQHVELYQKYSNNSWR
YLSNRLLTPSDSPEWLSFDVTGVVRQWLSQGGAMEGLRLSAHCPCDSKDNTLRVGINGFS
SSRRGDLATIDGMNRPFLLLMATPLERAQQLHSSRHRRALDTNYCSSSTEKNCCVRQLYI
DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQV
LEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgccgccctccggcctgcggctgctgccgctgctgctgccactgctgtggctactagtg
ctgacgcctggccggccagccgccggactgtccacctgcaagaccatcgacatggagctg
gtgaagcggaagcgcatcgaggccatccgcggccagatcctgtccaagttgcggctcgcc
agccccccgagccagggggaggttccgcccggcccgctgcccgaggccgtgctggccctt
tacaacagtacccgcgcccaggtggccggagagagcgctgagacggagcccgagcctgag
gcggactactacgccaaggaggtcacccgcgtgctaatggtggaaaaggaaaacgaaatc
tataagactgtggagaccggctcacacagcatatatatgttcttcaatgcgtcggagctc
cgggcagcagtgcccgatcccatgctgctctcccgggcagagctgcgcctcctaaggctc
aagttaagcgtggagcagcatgtggagctgtaccagaaatacagcaataattcctggcgc
tacctcagtaaccggctgctgacccccagcgactcgccggaatggctgtcctttgatgtc
accggagtcgtgcggcagtggctgagccagggaggggcaatggagggccttcgcctcagt
gcccactgcccctgtgacagcaaagataacacactccgcgtgggcatcaacgggttcagt
tccagccgccggggtgatctggccaccattgatggcatgaaccggcccttcctgctcctc
atggccaccccactggagagggcccagcagctgcacagctcccggcaccgccgagctctg
gacaccaactactgttccagctccacagagaagaactgctgcgtacggcagctgtacatt
gactttcgcaaggatctgggctggaagtggatccacgagcccaagggctaccacgccaac
ttctgcctggggccctgcccctacatttggagcctggacacgcagtacagcaaggtcctg
gccctgtacaaccagcacaacccgggcgcgtcggcggcgccgtgctgcgtgccgcaggtg
ctggagccgctgcccatcgtgtactacgtgggtcgcaagcccaaggtggagcagctgtcc
aacatgatcgtgcgctcctgcaagtgcagctga

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