Equus caballus (horse): 100033957
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Entry
100033957 CDS
T01058
Symbol
FLT1
Name
(RefSeq) vascular endothelial growth factor receptor 1 precursor
KO
K05096
FMS-like tyrosine kinase 1 [EC:
2.7.10.1
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb04010
MAPK signaling pathway
ecb04014
Ras signaling pathway
ecb04015
Rap1 signaling pathway
ecb04020
Calcium signaling pathway
ecb04066
HIF-1 signaling pathway
ecb04151
PI3K-Akt signaling pathway
ecb04510
Focal adhesion
ecb05202
Transcriptional misregulation in cancer
ecb05323
Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100033957 (FLT1)
04014 Ras signaling pathway
100033957 (FLT1)
04015 Rap1 signaling pathway
100033957 (FLT1)
04066 HIF-1 signaling pathway
100033957 (FLT1)
04020 Calcium signaling pathway
100033957 (FLT1)
04151 PI3K-Akt signaling pathway
100033957 (FLT1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100033957 (FLT1)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
100033957 (FLT1)
09163 Immune disease
05323 Rheumatoid arthritis
100033957 (FLT1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100033957 (FLT1)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100033957 (FLT1)
Protein kinases [BR:
ecb01001
]
Receptor tyrosine kinases (RTK)
VEGFR family [OT]
100033957 (FLT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ig_3
I-set
Pkinase
ig
Ig_2
VEGFR-1-like_Ig-like
V-set
Ig_VEGFR-1-like_5th
VEGFR-2_TMD
VEGFR1-3_N_Ig-like
C1-set
Ig_4
Ig_5
Haspin_kinase
Herpes_gE
Motif
Other DBs
NCBI-GeneID:
100033957
NCBI-ProteinID:
NP_001296400
Ensembl:
ENSECAG00000021700
VGNC:
18067
LinkDB
All DBs
Position
17:complement(8029298..8201369)
Genome browser
AA seq
1336 aa
AA seq
DB search
MISCWDAGVLLCALLGGLLLTGSSSGSKLKGPELSLKGTQHVMQAGQTLYLKCRGEAAHS
WSLPETVTKESKRLSISKSACGRNGKQFCSTLTLTTAQANHTGFYSCKYLSMPASKKKKT
ESRIYIFINDTGRPFLEMHSEIPEIIYMTEGREIVIPCRVTSPNITVTLKKFPLDTLIPD
GKRIIWDSRKGFIISNATYKEIGLLTCETTVNGHLFKTNYLTYRETNTITDVQIRTPSPV
KLLRGHTLTLNCTATTPLNTRVQMTWSYPGETNKRASIRQRIDQRNSHNNVFYSVLIIDK
VQNKDKGLYTCHVKSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK
AFPSPEVVWLKDGLLATEKSARYLVHGYSLIIKDVTAEDAGDYTILLGIKQSNMFKNLTA
TLIVNVKPQIYEKAVSSLPDPTLYPLGSRQILTCTIYGIPQPAVKWFWHPCNHNHSKARY
DFCSKNEESFILDPDSNIGNRIESITQRTAIIEGKNKTASTLVVADSRISGIYSCMASNK
VGTVERNMNFYVTDVPNGFHVNLEKMPTEGEDLKLSCTVNKFLYRDITWILLRTVNNRTM
HHSISKQKMAITKEYSITLHLIIKNVSLEDSGTYACRARNIYTGEEILQKKEVTIRDQEA
PYLLRNLSDHTVPISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILGPGSSTLFIER
VTEEDEGIYHCKATNQKGSVESSAYLTVQGTSDKSNLELITLTCTCVAATLFWLLLTLFI
RKLKRSSSEIKTDYLSIIMDPDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFGK
VVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGACTK
QGGPLMVIVEYCKYGNLSNYLKSKRDSFFLNKDAALHMELKKENMEPDLEQGKKQRLDSV
TSSESFASSGFQEDKSLSDVEEEEDSDDFCKQPITMEDLISYSFQVARGMEFLSSRKCIH
RDLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKS
DVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRAPEYATPEIYQIMLDCWHKD
PKERPRFAELVEKLGDLLQANVQQDGKDYIPLNAILTRNSGFTYSTPAFSEDFFKEDISA
PKFNSASSDNVRYVNAFNFMSLERIKTFEELSPDAPSMLDDYQVDSSTLLASPLLKRFTW
TESKPKASLKIDLRVTSKSKESGLSDLARPTFCHSSCGHLNSKRRFTYDNSELEKISCCS
PPPDYNSVVLYSTPPV
NT seq
4011 nt
NT seq
+upstream
nt +downstream
nt
atgatcagctgctgggacgccggggtcctgctgtgcgcgctgctcggcggtctgcttcta
acaggatctagttcaggttcaaaattaaaaggtcctgaactgagtttaaaaggcacccag
cacgtcatgcaagcaggccagacgctgtatctgaaatgcaggggggaagcagcccattcc
tggtctttgcctgaaacggtgactaaggaaagcaaaaggctgagcataagtaagtctgcc
tgtggaaggaacggcaaacagttctgcagcactttgaccttgaccacggctcaggcaaat
cacactggcttctacagctgcaaatatctgtccatgcctgcttcaaagaagaagaaaaca
gagtctagaatctatatatttattaatgatacaggtagacctttcttagagatgcacagt
gaaatacctgaaattatatatatgactgaaggaagggagatcgtcattccctgccgggtc
acatcacctaacatcactgttactttaaaaaagtttccacttgatactctgatccctgat
ggaaaaagaataatctgggacagtaggaagggttttataatatcaaatgcaacatacaaa
gaaatagggcttctgacctgtgaaacaacagtcaacggacatttgttcaagacaaactat
ctcacatatcgagaaaccaatacaatcacagatgtccaaatccgcacaccaagccccgtc
aagttactcagaggccatactctcaccctcaactgcactgctaccacgcccttaaacacg
agagttcaaatgacctggagttaccctggtgaaacaaataagagagcctctataaggcaa
cgaattgaccaacgcaattcccataacaacgtattctacagtgttctaattattgacaaa
gtgcagaacaaagacaaaggactttatacttgtcatgtaaagagtggcccatcattcaaa
tctgttaacacctcagtgcatatatatgataaagcattcatcactgtgaaacaccgaaaa
cagcaggtgctggaaactgtagctggcaagcggtcttaccggctatctatgaaagtgaag
gcatttccctcaccagaagttgtatggttaaaagatgggttacttgcgactgagaaatct
gctcgctatttggttcatggctattcattaattatcaaagacgtaactgcagaagacgca
ggggattatacaatcttgctgggcataaagcagtcaaatatgtttaaaaacctcaccgca
actctaattgtaaatgtgaaaccccagatttacgaaaaggctgtgtcatcgcttccagac
ccaactctctacccactgggcagcagacaaatcctgacctgtaccatttatggtatccct
caacctgcagtcaagtggttctggcatccctgtaaccacaatcattccaaagcaaggtat
gacttttgctccaaaaatgaagagtcctttatcctggatcctgacagcaacataggaaac
agaattgagagcatcactcagcgcacagcaataatagaaggaaagaataagacggctagc
accctggttgtggctgactctaggatttctggaatctacagttgcatggcttccaataaa
gtagggactgtggaaagaaacatgaacttttatgtcacagatgtgcccaatggatttcat
gttaacttggaaaaaatgcctacggaaggagaggacctgaaactgtcttgcacggttaac
aagttcttatacagagacattacttggattttgctgcggacagttaataaccgaacaatg
caccacagtattagcaagcaaaaaatggccatcaccaaagagtactccattactcttcat
ctaatcatcaagaatgtttccctggaagattcaggcacctatgcctgcagagccaggaac
atatatacaggggaagaaatccttcagaagaaagaagttacaattagagatcaggaagca
ccttacctcctgcgaaacctcagtgatcacacagtgcctatcagcagctctaccacttta
gactgtcacgctaacggcgtcccagagcctcagataacctggtttaaaaacaaccacaaa
atacaacaagaacctggaattattttaggaccaggaagcagcacgctgtttattgaaaga
gtcacagaagaggatgaaggcatctatcactgcaaagccaccaaccagaaggggtctgtg
gaaagttcagcatacctcactgttcaaggaacctcggacaagtctaatctggagctaatc
actctgacgtgtacgtgtgtggctgcaaccctcttctggctcctattaactctctttatc
cgaaaactaaaaaggtcttcttctgaaataaagactgactacctatcaattataatggac
ccagatgaagttcccctggatgagcagtgtgagcggctcccttatgatgccagcaagtgg
gagtttgcccgggagagacttaaactgggcaaatcacttggaagaggggcctttggaaaa
gtggttcaagcatctgcatttggcattaagaaatcacccacatgccggaccgtggctgta
aaaatgctgaaagagggggctacggccagtgaatacaaagctctgatgactgagctcaag
atcttgactcacattggccatcacctgaacgtagtcaacctgctgggagcctgcaccaag
caaggagggcctctgatggtgattgttgaatattgcaaatatggaaatctatccaactac
ctcaagagtaaacgagactcattctttctcaacaaggatgcagcattacacatggagctg
aagaaagaaaacatggagccagacctggaacaaggcaagaaacaaagactagatagtgtc
accagcagtgagagctttgcaagctccgggtttcaggaagataaaagtctgagtgatgtt
gaggaagaggaggactctgacgatttctgcaagcagcccatcactatggaggacctgatt
tcttacagttttcaagtggccagaggcatggagtttctgtcttccagaaagtgcattcat
cgggacctggcagcacgaaatattcttttatctgagaacaatgtggtgaagatttgcgat
tttggccttgcccgggatatttataagaaccccgattatgtgagaaaaggagatactcga
cttcctctgaaatggatggctcctgaatctatctttgacaaaatctacagcaccaagagt
gatgtgtggtcttatggagttctgctatgggaaatcttctccttaggtgggtctccatac
ccaggagtacaaatggatgaggacttctgcagtcgcctgaaggaaggcatgaggatgagg
gctcccgaatacgcaactcctgaaatctatcagatcatgttggactgctggcacaaagac
ccaaaagaaaggccaagatttgcagaacttgtggaaaaactaggcgatttgcttcaagca
aatgtacaacaggatggtaaagattatatcccactaaatgccatactgacaagaaatagt
gggtttacatactcaactcctgccttctctgaggacttcttcaaggaagatatttctgct
ccgaagtttaattcagcaagttctgataatgtcagatacgtaaatgctttcaatttcatg
agcttggaaagaatcaaaacctttgaagaactttcaccagatgccccttccatgcttgat
gattaccaggtggacagcagcactctgctggcctccccgctgctgaagcgcttcacctgg
actgagagcaaacccaaggcctcactaaagattgacctgagagtaaccagtaaaagcaag
gagtcggggctttctgacctcgccaggcctaccttctgccattccagctgtgggcacctc
aacagcaagcgcagattcacctacgacaactcggagctggagaagatctcgtgctgctct
cctcccccagactacaactcggtggtcttgtattccactccacctgtctaa
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